Dr hab. Anna Haduch
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Cytochrome P450 2D (CYP2D) enzyme dysfunction associated with aging and serotonin deficiency in the brain and liver of female Dark Agouti rats.
Anna Haduch, Przemysław J Danek, Wojciech Kuban, Renata Pukło, Natalia Alenina, Joanna Gołębiowska, Piotr Popik, Michael Bader, Władysława A Daniel
Neurochemistry international, S0197-0186(21)00269-2 10.1016/j.neuint.2021.105223
PMID:34780807 -
The effect of ageing and cerebral serotonin deficit on the activity of cytochrome P450 2D (CYP2D) in the brain and liver of male rats.
Anna Haduch, Renata Pukło, Natalia Alenina, Agnieszka Nikiforuk, Piotr Popik, Michael Bader, Władysława A Daniel
Neurochemistry international, S0197-0186(20)30275-8 10.1016/j.neuint.2020.104884
PMID:33091481 -
The engagement of brain cytochrome P450 in the metabolism of endogenous neuroactive substrates: a possible role in mental disorders.
Anna Haduch, Władysława Anna Daniel
Drug metabolism reviews, 10.1080/03602532.2018.1554674
PMID:30501426 -
The activity of brain and liver cytochrome P450 2D (CYP2D) is differently affected by antidepressants in the chronic mild stress (CMS) model of depression in the rat.
Anna Haduch, Marta Rysz, Mariusz Papp, Władysława A Daniel
Biochemical pharmacology, S0006-2952(18)30387-3 10.1016/j.bcp.2018.09.005
PMID:30195732 -
Melatonin Supports CYP2D-Mediated Serotonin Synthesis in the Brain.
Anna Haduch, Ewa Bromek, Jacek Wójcikowski, Krystyna Gołembiowska, Władysława A Daniel
Drug metabolism and disposition: the biological fate of chemicals, 10.1124/dmd.115.067413
PMID:26884482