Dr Ewa Bromek
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Chronic treatment with asenapine affects cytochrome P450 2D (CYP2D) in rat brain and liver. Pharmacological aspects.
Przemysław J Danek, Ewa Bromek, Anna Haduch, Władysława A Daniel
Neurochemistry international, S0197-0186(21)00255-2 10.1016/j.neuint.2021.105209
PMID:34666077
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The Selective NMDA Receptor GluN2B Subunit Antagonist CP-101,606 with Antidepressant Properties Modulates Cytochrome P450 Expression in the Liver.
Ewa Bromek, Anna Haduch, Marta Rysz, Joanna Jastrzębska, Renata Pukło, Olga Wójcikowska, Przemysław Jan Danek, Władysława Anna Daniel
Pharmaceutics, 1643 10.3390/pharmaceutics13101643
PMID:34683936
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The Influence of Long-Term Treatment with Asenapine on Liver Cytochrome P450 Expression and Activity in the Rat. The Involvement of Different Mechanisms.
Przemysław J Danek, Ewa Bromek, Władysława A Daniel
Pharmaceuticals (Basel, Switzerland), 629 10.3390/ph14070629
PMID:34209648
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The regulation of liver cytochrome P450 expression and activity by the brain serotonergic system in different experimental models.
Ewa Bromek, Władysława Anna Daniel
Expert opinion on drug metabolism & toxicology, 10.1080/17425255.2021.1872543
PMID:33400885
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The effects of agomelatine and imipramine on liver cytochrome P450 during chronic mild stress (CMS) in the rat.
Anna Haduch, Ewa Bromek, Marta Rysz, Renata Pukło, Mariusz Papp, Piotr Gruca, Magdalena Łasoń, Monika Niemczyk, Władysława A Daniel
Pharmacological reports : PR, 10.1007/s43440-020-00151-w
PMID:32748256
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Ewa Bromek, Marta Rysz, Anna Haduch, Władysława A Daniel
Pharmacological reports : PR, S1734-1140(19)30210-5 10.1016/j.pharep.2019.05.010
PMID:31671379
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Ewa Bromek, Marta Rysz, Anna Haduch, Władysława A Daniel
Drug metabolism and disposition: the biological fate of chemicals, 10.1124/dmd.118.083808
PMID:30518657
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Ewa Bromek, Marta Rysz, Anna Haduch, Jacek Wójcikowski, Władysława A Daniel
Drug metabolism and disposition: the biological fate of chemicals, 10.1124/dmd.117.079632
PMID:29555828
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Melatonin Supports CYP2D-Mediated Serotonin Synthesis in the Brain.
Anna Haduch, Ewa Bromek, Jacek Wójcikowski, Krystyna Gołembiowska, Władysława A Daniel
Drug metabolism and disposition: the biological fate of chemicals, 10.1124/dmd.115.067413
PMID:26884482
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The reverse role of the hypothalamic paraventricular (PVN) and arcuate (ARC) nuclei in the central serotonergic regulation of the liver cytochrome P450 isoform CYP2C11.
Marta Rysz, Ewa Bromek, Anna Haduch, Barbora Liskova, Jacek Wójcikowski, Władysława A Daniel
Biochemical pharmacology, 10.1016/j.bcp.2016.04.017 S0006-2952(16)30071-5
PMID:27137992
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Activation of brain serotonergic system by repeated intracerebral administration of 5-hydroxytryptophan (5-HTP) decreases the expression and activity of liver cytochrome P450.
Marta Rysz, Ewa Bromek, Władysława A Daniel
Biochemical pharmacology, 10.1016/j.bcp.2015.11.014 S0006-2952(15)00723-6
PMID:26581122
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Damage to the Brain Serotonergic System Increases the Expression of Liver Cytochrome P450.
Marta Rysz, Ewa Bromek, Anna Haduch, Anna Sadakierska-Chudy, Władysława A Daniel
Drug metabolism and disposition: the biological fate of chemicals, 10.1124/dmd.115.064980
PMID:26059263
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The role of the dorsal noradrenergic pathway of the brain (locus coeruleus) in the regulation of liver cytochrome P450 activity.
Marta Kot, Anna Sadakierska-Chudy, Anna Haduch, Marta Rysz, Ewa Bromek, Krystyna Gołembiowska, Wladyslawa A Daniel
European journal of pharmacology, 10.1016/j.ejphar.2015.01.014 S0014-2999(15)00036-9
PMID:25637782
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The cytochrome P450 2D-mediated formation of serotonin from 5-methoxytryptamine in the brain in vivo: a microdialysis study.
Anna Haduch, Ewa Bromek, Marta Kot, Katarzyna Kamińska, Krystyna Gołembiowska, Wladyslawa A Daniel
Journal of neurochemistry, 10.1111/jnc.13031
PMID:25581337
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Role of brain cytochrome P450 (CYP2D) in the metabolism of monoaminergic neurotransmitters.
Anna Anna Haduch, Ewa Bromek, Władysława A Daniel
Pharmacological reports : PR,
PMID:24553000
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Involvement of the paraventricular (PVN) and arcuate (ARC) nuclei of the hypothalamus in the central noradrenergic regulation of liver cytochrome P450.
Ewa Bromek, Jacek Wójcikowski, Władysława A Daniel
Biochemical pharmacology, 10.1016/j.bcp.2013.09.006 S0006-2952(13)00578-9
PMID:24051135
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The catalytic competence of cytochrome P450 in the synthesis of serotonin from 5-methoxytryptamine in the brain: an in vitro study.
Anna Haduch, Ewa Bromek, Anna Sadakierska-Chudy, Jacek Wójcikowski, Władysława A Daniel
Pharmacological research, 10.1016/j.phrs.2012.10.009 S1043-6618(12)00196-X
PMID:23098818
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Cytochrome P450 mediates dopamine formation in the brain in vivo.
Ewa Bromek, Anna Haduch, Krystyna Gołembiowska, Władysława A Daniel
Journal of neurochemistry, 10.1111/j.1471-4159.2011.07339.x
PMID:21651557
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The effect of psychotropic drugs on cytochrome P450 2D (CYP2D) in rat brain.
Anna Haduch, Ewa Bromek, Władysława A Daniel
European journal of pharmacology, 10.1016/j.ejphar.2010.10.077
PMID:21115002
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The ability of cytochrome P450 2D isoforms to synthesize dopamine in the brain: An in vitro study.
Ewa Bromek, Anna Haduch, Władysława A Daniel
European journal of pharmacology, 10.1016/j.ejphar.2009.09.062
PMID:19818757
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Effect of mirtazapine on the CYP2D activity in the primary culture of rat hepatocytes.
Anna Haduch, Ewa Bromek, Marta Kot, Katalin Jemnitz, Zsuzsa Veres, László Vereczkey, Władysława A Daniel
Pharmacological reports : PR,
PMID:17220559
Wszystkie publikacje
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Czy neuroprzekaźniki mózgowe mogą sterować pracą enzymów wątrobowych?
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„Udział mózgowych receptorów serotoninergicznych 5-HT6 i 5-HT7 w regulacji wątrobowego cytochromu P450”.
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• Stypendium konferencyjne na 15th International Conference on Cytochromes P450. Biochemistry, Biophysics, Functional Genomics. Bled, Slovenia, 17-21.06.2007
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• Stypendium konferencyjne na 11th World Congress of Biological Psychiatry 23.06-27.06.2013
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• Stypendium konferencyjne PROM2 - ISSX/MDO 2022: the 24th International Symposium on Microsomes and Drug Oxidations (MDO) and 13th International Meeting of the International Society for the Study of Xenobiotics (ISSX), 11 – 14 September 2022 Seattle, USA.
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Międzynarodowa
- Department of Pharmacology, Faculty of Medicine, Masaryk University, Brno
