CONTENTS (PDF format)

Review - Melatonin in experimental seizures and epilepsy. Monika Banach, Elwira Gurdziel, Marian Jędrych, Kinga K. Borowicz (p. 1) Abstract / Article (PDF format) Review - Caffeine and the anticonvulsant potency of antiepileptic drugs: experimental and clinical data. Magdalena Chrościńska-Krawczyk, Małgorzata Jargiełło-Baszak, Magdalena Wałek, Bożydar Tylus, Stanisław J. Czuczwar (p. 12) Abstract / Article (PDF format) Review - Protein kinase Cepsilon as a cancer marker and target for anticancer therapy. Ewa Totoń, Ewa Ignatowicz, Karolina Skrzeczkowska, Maria Rybczyńska (p. 19) Abstract / Article (PDF format) Review - IL-17-expressing cells as a potential therapeutic target for treatment of immunological disorders. Anna Strzępa, Marian Szczepanik (p. 30) Abstract / Article (PDF format) Differences between human wild-type and C23S variant 5-HT2C receptors in inverse agonist-induced resensitization. Jutta Walstab, Folkert Steinhagen, Michael Brüss, Manfred Göthert, Heinz Bönisch (p. 45) Abstract / Article (PDF format) Ameliorative potential of sodium cromoglycate and diethyldithiocarbamid acid in restraint stress-induced behavioral alterations in rats. Rajneet K. Manchanda, Amteshwar S. Jaggi, Nirmal Singh (p. 54) Abstract / Article (PDF format) Magnesium sulfate and sodium valproate block methylphenidate-induced hyperlocomotion, an animal model of mania. Francisco J. Barbosa, Bernardete Hesse, Rodrigo B. de Almeida, Irinéia P. Baretta, Roseli Boerngen-Lacerda, Roberto Andreatini (p. 64) Abstract / Article (PDF format) Antidepressant-like activity of the phenylpiperazine pyrrolidin-2-one derivatives in mice. Jacek Sapa, Barbara Filipek, Katarzyna Kulig, Barbara Malawska (p. 71) Abstract / Article (PDF format) Acquisition and expression of ethanol-induced conditioned place preference in mice is inhibited by naloxone. Małgorzata Wróbel (p. 79) Abstract / Article (PDF format) Effects of carbamazepine and metabolites on IL-2, IL-5, IL-6, IL-10 and IFN-gamma secretion in epileptic patients: the influence of co-medication. Olivier Mathieu, Marie-Christine Picot, Philippe Gelisse, Hélene Breton, Pascal Demoly, Dominique Hillaire-Buys (p. 86) Abstract / Article (PDF format) Lymphocyte-suppressing effect of simvastatin in mixed dyslipidemic patients but not impaired glucose tolerance patients. Robert Krysiak, Bogusław Okopień (p. 95) Abstract / Article (PDF format) Noradrenaline release in rodent tissues is inhibited by interleukin-1beta but is not affected by urotensin II, MCH, NPW and NPFF. Kirsten Schulte, Manush Kumar, Jean-Marie Zajac, Eberhard Schlicker (p. 102) Abstract / Article (PDF format) Heme oxygenase/carbon monoxide-biliverdin pathway may be involved in the antinociceptive activity of etoricoxib, a selective COX-2 inhibitor. Niedja M. G. Grangeiro, Jordana A. Aguiar, Hellíada V. Chaves, Antonio A. R. Silva, Vilma Lima, Norma M. B. Benevides, Gerly A. C. Brito, José R. V. da Graça, Mirna M. Bezerra (p. 112) Abstract / Article (PDF format) Evaluation of the irritating influence of carane derivatives and their antioxidant properties in a deoxyrybose degradation test. Andrzej Moniczewski, Tadeusz Librowski, Stanisław Lochyński, Daniel Strub (p. 120) Abstract / Article (PDF format) Ejaculatory dysfunction in streptozotocin-induced diabetic rats: the role of testosterone. Davi A. Pontes, Glaura S. A. Fernandes, Renata C. Piffer, Daniela C. C. Gerardin, Oduvaldo C. M. Pereira, Wilma G. Kempinas (p. 130) Abstract / Article (PDF format) Enhanced TRAIL-mediated apoptosis in prostate cancer cells by the bioactive compounds neobavaisoflavone and psoralidin isolated from Psoralea corylifolia. Ewelina Szliszka, Zenon P. Czuba, Łukasz Sędek, Andrzej Paradysz, Wojciech Król (p. 139) Abstract / Article (PDF format) Influence of anticancer therapy on oxidation phenotype and acetylation phenotype in patients with acute myeloblastic leukemia. Łukasz Łapiński, Krystyna Orzechowska-Juzwenko, Anna Wiela-Hojeńska, Dariusz Wołowiec, Grzegorz Ganczarski, Krystyna Głowacka, Henryk Czarnik-Matusewicz, Kazimierz Kuliczkowski, Jacek Gąsiorowski (p. 149) Abstract / Article (PDF format) Induction of P450 3A1/2 and 2C6 by gemfibrozil in Sprague-Dawley rats. Aiming Liu, Julin Yang, Xin Zhao, Xiaolan Jiao, Weihong Zhao, Qing Ma, Zhiyuan Tang, Renke Dai (p. 157) Abstract / Article (PDF format) SHORT COMMUNICATIONS Endocannabinoid system protects against cryptogenic seizures. Clementina M. van Rijn, Martin F. J. Perescis, Lyudmila Vinogradova, Gilles van Luijtelaar (p. 165) Abstract / Article (PDF format) 7-Nitroindazole, but not NG-nitro-L-arginine, enhances the anticonvulsant activity of pregabalin in the mouse maximal electroshock-induced seizure model. Jarogniew J. Łuszczki, Anna Jaskólska, Wojciech Dworzański, Dorota Żółkowska (p. 169) Abstract / Article (PDF format) Cytoprotective action of the potassium channel opener NS1619 under conditions of disrupted calcium homeostasis. Ludwika Chmielewska, Dominika Malińska (p. 176) Abstract / Article (PDF format) Atorvastatin affects the tissue concentration of hydrogen sulfide in mouse kidneys and other organs. Bogdan Wiliński, Jerzy Wiliński, Eugeniusz Somogyi, Joanna Piotrowska, Marta Góralska (p. 184) Abstract / Article (PDF format) Combinatory effects of PBDEs and 17beta-estradiol on MCF-7 cell proliferation and apoptosis. Patrycja Kwiecińska, Anna Wróbel, Ewa Ł. Gregoraszczuk (p. 189) Abstract / Article (PDF format) Cell-penetrating peptides modulate the vascular action of phenylephrine. Ivan Kocić, Jarosław Ruczyński, Renata Szczepańska, Mariola Olkowicz, Brygida Parfianowicz, Izabela Rusiecka, Piotr Rekowski (p. 195) Abstract / Article (PDF format) Abstracts of the EUROPEAN OPIOID CONFERENCE, 2011, Kraków, Poland Programme (p. 201) Plenary lectures (p. 205) Symposia (p. 207) Posters (p. 226)

CONTENTS (PDF format)

Review - Basic mechanisms of antiepileptic drugs and their pharmacokinetic/pharmacodynamic interactions: an update. Władysław Lasoń, Monika Dudra-Jastrzębska, Konrad Rejdak, Stanisław J. Czuczwar (p. 271) Abstract / Article (PDF format) Review - Pharmacoepigenetics: a new approach to predicting individual drug responses and targeting new drugs. Wanda Baer-Dubowska, Aleksandra Majchrzak-Celińska, Michał Cichocki (p. 293) Abstract / Article (PDF format) Review - Natural and synthetic acridines/acridones as antitumor agents: their biological activities and methods of synthesis. Grzegorz Cholewiński, Krystyna Dzierzbicka, Aleksander M. Kołodziejczyk (p. 305) Abstract / Article (PDF format) Review - Therapeutic potential of the biscoclaurine alkaloid, cepharanthine, for a range of clinical conditions. Moshe Rogosnitzky, Rachel Danks (p. 337) Abstract / Article (PDF format) Functional changes in transcriptomes of the prefrontal cortex and hippocampus in a mouse model of anxiety. Dezsom P. Virok, Zoltán Kis, Viktor Szegedi, Gábor Juhász, Ágnes Zvara, Jr., Géza Müller, György Lévay, László G. Hársing, Róbert Rajkó, Botond Penke, Zoltán Janka, Tamás Janáky, László G. Puskás (p. 348) Abstract / Article (PDF format) Effects of bupropion on the reinstatement of nicotine-induced conditioned place preference by drug priming in rats. Barbara Budzyńska, Grażyna Biała (p. 362) Abstract / Article (PDF format) Concomitant use of carbamazepine and olanzapine and the effect on some behavioral functions in rats. Elżbieta Nowakowska, Krzysztof Kus, Adam Polański, Kinga Burda, Anna Nowakowska, Czesław Sadowski (p. 372) Abstract / Article (PDF format) Increases in beta-amyloid protein in the hippocampus caused by diabetic metabolic disorder are blocked by minocycline through inhibition of NF-kappaB pathway activation. Zhiyou Cai, Yu Zhao, Shengtao Yao, Bin Zhao (p. 381) Abstract / Article (PDF format) Immunosuppressant cytoprotection correlates with HMGB1 suppression in primary asctrocyte cultures exposed to combined oxygen-glucose deprivation. Bożena Gabryel, Anna Bielecka, Jacek Bernacki, Krzysztof Łabuzek, Zbigniew S. Herman (p. 392) Abstract / Article (PDF format) Kinetic studies of the effects of Temodal and quercetin on astrocytoma cells. Joanna Jakubowicz-Gil, Ewa Langner, Wojciech Rzeski (p. 403) Abstract / Article (PDF format) Effects of norepinephrine on the electrical activities of pain-related neurons in the rat nucleus accumbens. Duo Zhang, Dong-Xiao Yang, Chun-Xiao Yang, Guang-Wen Zhang, He-Ren Gao, Ye Zhai, Run-Sheng Jiao, Ying Zhang, Hui Zhang, Yu Liang, Man-Ying Xu (p. 417) Abstract / Article (PDF format) Interaction between histamine and morphine at the level of the hippocampus in the formalin-induced orofacial pain in rats. Esmaeal Tamaddonfard, Amir Erfanparast, Amir Abbas Farshid, Emad Khalilzahdeh (p. 423) Abstract / Article (PDF format) Synergism between dexketoprofen and meloxicam in an orofacial formalin test was not modified by opioid antagonists. Claudia Gonzalez, Carlos Zegpi, Viviana Noriega, Juan C. Prieto, Hugo F. Miranda (p. 433) Abstract / Article (PDF format) Impact of fluoxetine on liver damage in rats. Iwona Inkielewicz-Stępniak (p. 441) Abstract / Article (PDF format) Vasopressor and heart rate responses to systemic administration of bombesin in anesthetized rats. Katarzyna Kaczyńska, Małgorzata Szereda-Przestaszewska (p. 448) Abstract / Article (PDF format) Antiarrhythmic and hypotensive activities of 1-[2-hydroxy-3-(4-phenyl-1-piperazinyl)propyl]-pyrrolidin-2-one (MG-1(R,S)) and its enantiomers. Jacek Sapa, Barbara Filipek, Leszek Nowiński (p. 455) Abstract / Article (PDF format) Modified C-reactive protein interacts with platelet glycoprotein Ibalpha. Magdalena Boncler, Joanna Rywaniak, Jacek Szymański, Lawrence A. Potempa, Błażej Rychlik, Cezary Watała (p. 464) Abstract / Article (PDF format) Structure-cardiovascular activity relationships in a group of new 8-alkylamino-1,3-dimethyl-7-(2-hydroxy-3-aminopropyl)-3,7-dihydro-1H-purine-2,6-diones. Grażyna Chłoń-Rzepa, Paweł Żmudzki, Maciej Pawłowski, Małgorzata Zygmunt, Barbara Filipek (p. 476) Abstract / Article (PDF format) Insulin suppresses the expression and function of breast cancer resistance protein in primary cultures of rat brain microvessel endothelial cells. Xiang Liu, Xin-yue Jing, Shi Jin, Yang Li, Li Liu, Yun-li Yu, Xiao-dong Liu, Lin Xie (p. 487) Abstract / Article (PDF format) Protective effects of endothelin-A receptor antagonist BQ123 against LPS-induced oxidative stress in lungs. Aleksandra Piechota, Andrzej Polańczyk, Anna Goraca (p. 494) Abstract / Article (PDF format) Estimation of the action of three different mechlorethamine doses on biochemical parameters during experimentally induced pleuritis in rats. Ireneusz Całkosiński, Joanna Rosińczuk-Tonderys, Katarzyna Dzierzba, Agnieszka Bronowicka-Szydełko, Ewa Seweryn, Jacek Majda, Monika Całkosińska, Andrzej Gamian (p. 501) Abstract / Article (PDF format) Antiulcerative effect of dexmedetomidine on indomethacin-induced gastric ulcer in rats. Beyzagul Polat, Yavuz Albayrak, Bahadir Suleyman, Hakan Dursun, Fahmi Odabasoglu, Murat Yigiter, Zekai Halici, Halis Suleyman (p. 518) Abstract / Article (PDF format) Epigallocatechin gallate accelerates healing of indomethacin-induced stomach ulcers in mice. Biplab Adhikary, Sudhir K. Yadav, Sandip K. Bandyopadhyay, Subrata Chattopadhyay (p. 527) Abstract / Article (PDF format) SHORT COMMUNICATIONS Chronic unpredictable stree-induced reduction in the hippocampal brain-derived neurotrophic factor (BDNF) gene expression is antagonized by zinc treatment. Katarzyna Cieślik, Magdalena Sowa-Kućma, Grażyna Ossowska, Beata Legutko, Małgorzata Wolak, Włodzimierz Opoka, Gabriel Nowak (p. 537) Abstract / Article (PDF format) Sphingosine-1-phosphate augments agonist-mediated contraction in the bronchial smooth muscles of mice. Yoshihiko Chiba, Hiroki Takeuchi, Hiroyasu Sakai, Miwa Misawa (p. 544) Abstract / Article (PDF format) Effect of kynurenic acid on the viability of probiotics in vitro. Jadwiga Dolecka, Teresa Urbanik-Sypniewska, Barbara Skrzydło-Radomańska, Jolanta Parada-Turska (p. 548) Abstract / Article (PDF format) Abstracts of the THE TWENTIETH DAYS OF NEUROPSYCHOPHARMACOLOGY (p. 553) (Title page) Plenary lectures (p. 555) Oral presentations (p. 560) Posters (p. 589)

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Review - Therapeutic potential of adenosine analogues and conjugates. Monika Samsel, Krystyna Dzierzbicka (p. 601) Abstract / Article (PDF format) Review - Role of vinpocetine in cerebrovascular diseases. Sazal Patyar, Ajay Prakash, Manish Modi, Bikash Medhi (p. 618) Abstract / Article (PDF format) Review - Treatment of inflammatory bowel disease (IBD). Anand B. Pithadia, Sunita Jain (p. 629) Abstract / Article (PDF format) Review - Activity of essential phospholipids (EPL) from soybean in liver diseases. Karl-Josef Gundermann, Ann Kuenker, Erwin Kuntz, Marek Droździk (p. 643) Abstract / Article (PDF format) Thymoquinone produced antianxiety-like effects in mice through modulation of GABA and NO levels. Neeraj Gilhotra, Dinesh Dhingra (p. 660) Abstract / Article (PDF format) AM251, cannabinoids receptors ligand, improves recognition memory in rats. Izabela Bialuk, Maria M. Winnicka (p. 670) Abstract / Article (PDF format) Effect of nitric oxide synthase inhibitors on benzodiazepine withdrawal in mice and rats. Sylwia Talarek, Joanna Listos, Sylwia Fidecka (p. 680) Abstract / Article (PDF format) Nefopam enhances the protective activity of antiepileptics against maximal electroshock-induced convulsions in mice. Mirosław Czuczwar, Katarzyna Czuczwar, Jacek Cięszczyk, Jacek Kiś, Tomasz Saran, Jarogniew J. Łuszczki, Waldemar A. Turski (p. 690) Abstract / Article (PDF format) Riluzole prevents morphine-induced apoptosis in rat cerebral cortex. Kambiz Hassanzadeh, Leila Roshangar, Bohlool Habibi-asl, Safar Farajnia, Esmael Izadpanah, Mahboob Nemati, Modabber Arasteh, Sadollah Mohammadi (p. 697) Abstract / Article (PDF format) Anti-apoptotic effect of phloretin on cisplatin-induced apoptosis in HEI-OC1 auditory cells. Byung-Min Choi, Xiao Yan Chen, Shang Shang Gao, Rizhe Zhu, Bok-Ryang Kim (p. 708) Abstract / Article (PDF format) Activation of orexin/hypocretin type 1 receptors stimulates cAMP synthesis in primary cultures of rat astrocytes. Agata Woldan-Tambor, Kaja Biegańska, Anna Wiktorowska-Owczarek, Jolanta B. Zawilska (p. 717) Abstract / Article (PDF format) No protective effect of curcumin on hydrogen peroxide-induced cytotoxicity in HepG2 cells. Xiuping Chen, Zhangfeng Zhong, Zengtao Xu, Lidian Chen, Yitao Wang (p. 724) Abstract / Article (PDF format) Prevention of the wortmannin-induced inhibition of phosphoinositide 3-kinase by sulfhydryl reducing agents. Minoru Isosaki, Hitoshi Nakayama, Yoji Kyotani, Jing Zhao, Sayuko Tomita, Hiroyasu Satoh, Masanori Yoshizumi (p. 733) Abstract / Article (PDF format) Effects of angiotensin-converting enzyme inhibitors beyond lowering blood pressure - are they important for doctors? Michał Holecki, Jan Szewieczek, Jerzy Chudek (p. 740) Abstract / Article (PDF format) Administration of L-carnitine and mildronate improves endothelial function and decreases mortality in hypertensive Dahl rats. Reinis Vilskersts, Janis Kuka, Baiba Svalbe, Helena Cirule, Edgars Liepinsh, Solveiga Grinberga, Ivars Kalvinsh, Maija Dambrova (p. 752) Abstract / Article (PDF format) Hemostatic effects of bezafibrate and omega-3 fatty acids in isolated hypertriglyceridemic patients. Robert Krysiak, Anna Gdula-Dymek, Bogusław Okopień (p. 763) Abstract / Article (PDF format) N-phenylmaleimide derivatives as mimetic agents of the pro-inflammatory process: myeloperoxidasee activation. Vânia F. Noldin, Silvana V.G. Vigil, Rafael De Liz, Valdir Cechinel-Filho, Taniâ S. Fröde, Tânia B. Creczynski-Pasa (p. 772) Abstract / Article (PDF format) Puerarin inhibits iNOS, COX-2 and CRP expression via suppression of NF-kappaB activation in LPS-induced RAW264.7 macrophage cells. Wenzhi Hu, Xiangjun Yang, Cao Zhe, Qin Zhang, Lie Sun, Kejiang Cao (p. 781) Abstract / Article (PDF format) Naturally appearing N-feruloylserotonin isomers suppress oxidative burst of human neutrophils at the protein kinase C level. Rado Nosáľ, Tomáš Perečko, Viera Jančinová, Katarína Drábiková, Juraj Harmatha, Klara Sviteková (p. 790) Abstract / Article (PDF format) Primary and secondary clarithromycin, metronidazole, amoxicillin and levofloxaxin resistance to Helicobacter pylori in southern Poland. Elżbieta Karczewska, Izabela Wojtas-Bonior, Edward Sito, Małgorzata Zwolińska-Wcisło, Alicja Budak (p. 799) Abstract / Article (PDF format) Frequency of the C1236T, G2677T/A and C3435T MDR1 gene polymorphisms in the Serbian population. Maja Milojkovic, Slavica Stojnev, Ivan Jovanovic, Srdjan Ljubisavljevic, Vladisav Stefanovic, Raute Sunder-Plassman (p. 808) Abstract / Article (PDF format) Influence of ABCB1, CYP3A4*18B and CYP3A5*3 polymorphisms on cyclosporine A pharmacokinetics in bone marrow transplant recipients. Feng Qiu, Xiao-Jing He, Ya-Xin Sun, Jesse Li-Ling, Li-Mei Zhao (p. 815) Abstract / Article (PDF format) Association of transcription factor 7-like 2 (TCF7L2) gene polymorphism with posttransplant diabetes mellitus in kidney transplant patients medicated with tacrolimus. Mateusz Kurzawski, Krzysztof Dziewanowski, Karolina Kędzierska, Anna Wajda, Joanna Lapczuk, Marek Droździk (p. 826) Abstract / Article (PDF format) SHORT COMMUNICATIONS N-palmitoylethanolamide, an endocannabinoid, exhibits antidepressant effects in the forced swim test and the tail suspension test in mice. Hai-Ling Yu, Xian-Qing Deng, Ying-Jun Li, Ying-Chun Li, Zhe-Shan Quan, Xian-Yu Sun (p. 834) Abstract / Article (PDF format) Effect of neuraminidase treatment on persistent epileptiform activity in the rat hippocampus. Elena Isaeva, Irina Lushnikova, Alina Savrasova, Galina Skibo, Gregory L. Holmes, Dmytro Isaev (p. 840) Abstract / Article (PDF format) Erratum for: Pharmacol. Rep., 2011, 63, no. 2 (p. 845) PDF format

CONTENTS (PDF format)

Review - Lipoic acid - biological activity and therapeutic potential. Anna Gorąca, Halina Huk-Kolega, Aleksandra Piechota, Paulina Kleniewska, Elżbieta Ciejka, Beata Skibska (p. 849) Abstract / Article (PDF format) Review - Statin-induced myopathies. Michał Tomaszewski, Karolina M. Stępień, Joanna Tomaszewska, Stanisław J. Czuczwar (p. 859) Abstract / Article (PDF format) Review - Novel mechanistic and clinical implications concerning the safety of statin discontinuation. Magdalena Jasińska-Stroschein, Jacek Owczarek, Irena Wejman, Daria Orszulak-Michalak (p. 867) Abstract / Article (PDF format) Anxiolytic-like activity of MGS0039, a selective group II mGlu receptor antagonist, is serotonin- and GABA-dependent. Katarzyna Stachowicz, Joanna Wierońska, Helena Domin, Shigeyuki Chaki, Andrzej Pilc (p. 880) Abstract / Article (PDF format) Behavioral deficits and exaggerated feedback control over raphe-hippocampal serotonin neurotransmission in restrained rats. Darakhshan J. Haleem (p. 888) Abstract / Article (PDF format) Influence of aripiprazole on the antidepressant, anxiolytic and cognitive functions of rats. Kinga Burda, Anna Czubak, Krzysztof Kus, Elżbieta Nowakowska, Piotr Ratajczak, Jennifer Zin (p. 898) Abstract / Article (PDF format) Buspirone improves the anti-cataleptic effect of levodopa in 6-hydroxydopamine-lesioned rats. Javad Mahmoudi, Alireza Mohajjel Nayebi, Morteza Samini, Siamak Reyhani-Rad, Vahab Babapour (p. 908) Abstract / Article (PDF format) Neuroprotective effect of carvedilol against aluminium induced toxicity: possible behavioral and biochemical alterations in rats. Anil Kumar, Atish Prakash, Samrita Dogra (p. 915) Abstract / Article (PDF format) Non-neutral nonsynonymous single nucleotide polymorphisms in human ABC transporters: the first comparison of six prediction methods. Da Cheng Hao, Yao Feng, Rongrong Xiao, Pei Gen Xiao (p. 924) Abstract / Article (PDF format) Transdermal buprenorphine in the treatment of cancer and non-cancer pain - the results of multicenter studies in Poland. Anna Przeklasa-Muszyńska, Jan Dobrogowski (p. 935) Abstract / Article (PDF format) Involvement of kainate receptors in the analgesic but not hypnotic effects induced by inhalation anesthetics. Li-Hua Hang, Dong-Hua Shao, Yue-Ping Gu, Ti-Jun Dai (p. 949) Abstract / Article (PDF format) Beneficial role of telmisartan on cardiovascular complications associated with STZ-induced type 2 diabetes in rats. Bhoomika R. Goyal, Kaushal Parmar, Ramesh K. Goyal, Anita A. Mehta (p. 956) Abstract / Article (PDF format) Protective effect of novel pyridoindole derivatives on ischemia/reperfusion injury of the isolated rat heart. Zuzana Broskova, Vladimir Knezl (p. 967) Abstract / Article (PDF format) Long-term use of low-dose spironolactone in spontaneously hypertensive rats: Effects on left ventricular hypertrophy and stiffness. Marcelo P. Baldo, Ludimila Forechi, Elis A.S. Morra, Divanei Zaniqueli, Rebeca C. Machado, Wellington Lunz, Sérgio L. Rodrigues, José Geraldo Mill (p. 975) Abstract / Article (PDF format) Can vitamins C and E restore androgen level and hypersensivity of the vas deferens in hyperglycemic rats? Glaura S.A. Fernandes, Daniela C.C. Gerardin, Thaiane A. Assumpçao, Kleber E. Campos, Débora C. Damasceno, Oduvaldo C. M. Pereira, Wilma D.G. Kempinas (p. 983) Abstract / Article (PDF format) C3435T polymorphism of the ABCB1 gene: impact on genetic susceptibility to peptic ulcers. Aleksandra Sałagacka, Malwina Bartczak, Marta Żebrowska, Marcin Jażdżyk, Mariusz Balcerczak, Robert Janiuk, Marek Mirowski, Ewa Balcerczak (p. 992) Abstract / Article (PDF format) Association between remote organ injury and tissue polyamine homeostasis in acute experimental pancreatitis - treatment with a polyamine analogue bismethylspermine. Hai-Tao Jin, Teemu Lämsä, Panu H. Nordback, Mervi T. Hyvönen, Nikolay Grigorenko, Alex R. Khomutov, Isto Nordback, Sari Räty, Ilkka Pörsti, Leena Alhonen, Juhani Sand (p. 999) Abstract / Article (PDF format) Antiatherogenic effect of quercetin is mediated by proteasome inhibition in the aorta and circulating leukocytes. Denis A. Pashevin, Lesya V. Tumanovska, Victor E. Dosenko, Vasyl S. Nagibin, Veronika L. Gurianova, Alexey A. Moibenko (p. 1009) Abstract / Article (PDF format) Effect of indometacin pretreatment on protamine sulfate-mediated relaxation of the isolated rat uterus: the role of the antioxidative defense system. Jelena Kordić-Bojinović, Zorana Oreščanin-Dušić, Marija Slavić, Ratko Radojičić, Mihajlo Spasić, Slobodan R. Milovanović, Duško Blagojević (p. 1019) Abstract / Article (PDF format) Anti-inflammatory effects of LASSBio-998, a new drug candidate designed to be a p38 MAPK inhibitor, in an experimental model of acute lung inflammation. Aline C. Brando Lima, Alexandre L. Machado, Patrícia Simon, Moisés M. Cavalcante, Daniele C. Rezende, Gilberto M. Sperandio da Silva, Paulo Gustavo B.D. Nascimento, Luis E.M. Quintas, Fernando Q. Cunha, Eliezer J. Barreiro, Lídia M. Lima, Vera L.G. Koatz (p. 1029) Abstract / Article (PDF format) Effects of propranolol on the development of glucocorticoid-induced osteoporosis in male rats. Joanna Folwarczna, Maria Pytlik, Leszek Śliwiński, Urszula Cegieła, Barbara Nowińska, Monika Rajda (p. 1040) Abstract / Article (PDF format) SHORT COMMUNICATIONS Anxiolytic-like activity of zinc in rodent tests. Anna Partyka, Magdalena Jastrzębska-Więsek, Bernadeta Szewczyk, Katarzyna Stachowicz, Anna Sławińska, Ewa Poleszak, Urszula Doboszewska, Andrzej Pilc, Gabriel Nowak (p. 1050) Abstract / Article (PDF format) Dopaminergic drug-induced modulation of the expression of the dopamine transporter in peripheral blood lymphocytes in Parkinson's disease. Alessandra Fanciulli, Roberta Misasi, Dario Campanelli, Francesca R. Buttarelli, Francesco E. Pontieri (p. 1056) Abstract / Article (PDF format) Neuropeptide FF receptor modulates potassium currents in a dorsal root ganglion cell line. Catherine Mollereau, Michel Roumy, Jean-Marie Zajac (p. 1061) Abstract / Article (PDF format) Effects of the antioxidant baicalein on the pharmacokinetics of nimodipine in rats: a possible role of P-glycoprotein and CYP3A4 inhibition by baicalein. Young-Ah Cho, Jun-Shik Choi, Jin-Pil Burm (p. 1066) Abstract / Article (PDF format)

CONTENTS (PDF format)

Neonatal serotonin (5-HT) depletion does not disrupt prepulse inhibition of the startle response in rats. Paulina Kołomańska, Edyta Wyszogrodzka, Paulina Rok-Bujko, Paweł Krząścik, Wojciech Kostowski, Magdalena Zaniewska, Małgorzata Filip, Roman Stefański (p. 1077) Abstract / Article (PDF format) Locomotor activity changes in female adolescent and adult rat during repeated treatment with a cannabinoid or club drug. Jenny L. Wiley, Rhys L. Evans, Darren B. Grainger, Katherine L. Nicholson (p. 1085) Abstract / Article (PDF format) Elimination kinetics of the novel prodrug cinazepam possessing psychotropic activity in mice. Sergei I. Schukin, Vladymyr G. Zinkovsky, Olga V. Zhuk (p. 1093) Abstract / Article (PDF format) Curcumin mediates presenilin-1 activity to reduce beta-amyloid production in a model of Alzheimer's disease. Zhang Xiong, Zhang Hongmei, Si Lu, Li Yu (p. 1101) Abstract / Article (PDF format) Betulin, betulinic acid nd butein are inhibitors of acetaldehyde-induced activation of liver stellate cells. Agnieszka Szuster-Ciesielska, Krzysztof Plewka, Martyna Kandefer-Szerszeń (p. 1109) Abstract / Article (PDF format) Atorvastatin and fenofibric acid differentially affect the release of adipokines in the visceral and subcutaneous cultures of adipocytes that were obtained from patients with and without mixed dyslipidemia. Krzysztof Łabuzek, Łukasz Bułdak, Anna Duława-Bułdak, Anna Bielecka, Robert Krysiak, Andrzej Madej, Bogusław Okopień (p. 1124) Abstract / Article (PDF format) IFN-gamma suppresses the high glucose-induced increase in TGF-beta1 and CTGF synthesis in mesangial cells. Juan Du, Lining Wang, Linlin Liu, Qiuling Fan, Li Yao, Yan Cui, Ping Kang, Hong Zhao, Xin Feng, Hui Gao (p. 1137) Abstract / Article (PDF format) Anti-hypertensive effects of probenecid via inhibition of the alpha-adrenergic receptor. Jin Baek Park, Sung-Jin Kim (p. 1145) Abstract / Article (PDF format) Lymphocyte-suppressing action of angiotensin-converting enzyme inhibitors in coronary artery disease patients with normal blood pressure. Robert Krysiak, Bogusław Okopień (p. 1151) Abstract / Article (PDF format) Potentiation of neuronal insulin signaling and glucose uptake by resveratrol: the involvement of AMPK. Mayur I. Patel, Amit Gupta, Chinmoy S. Dey (p. 1162) Abstract / Article (PDF format) New derivative of staphylokinase SAK-RGD-K2-Hirul exerts thrombolytic effects in the arterial thrombosis model in rats. Janusz Szemraj, Agnieszka Zakrzeska, George Brown, Adrian Stankiewicz, Anna Gromotowicz, Tomasz Grędziński, Ewa Chabielska (p. 1169) Abstract / Article (PDF format) Protective effect of alpha-lipoic acid on oxidized low density lipoprotein-induced human umbilical vein endothelial cell injury. Yan-Xia Liu, Guo-Zhu Han, Tao Wu, Pang Liu, Qin Zhou, Ke-Xin Liu, Hui-Jun Sun (p. 1180) Abstract / Article (PDF format) Nitric oxide scavenging modulates mitochondrial dysfunction induced by hypoxia/reoxygenation. Emmanuel Robin, Alexandre Derichard, Benoit Vallet, Sidi Mohamed Hassoun, Remi Neviere (p. 1189) Abstract / Article (PDF format) Effects of valproic acid (VPA) and levetiracetam (LEV) on proliferation, apoptosis and hormone secretion of the human choriocarcinoma BeWo cell line. Patrycja Kwiecińska, Justyna Wiśniewska, Ewa Ł. Gregoraszczuk (p. 1195) Abstract / Article (PDF format) Role of IL-6 and neopterin in the pathogenesis of herpetic encephalitis. Monika Bociąga-Jasik, Andrzej Cieśla, Anna Kalinowska-Nowak, Paweł Skwara, Aleksander Garlicki, Tomasz Mach (p. 1203) Abstract / Article (PDF format) Chemopreventive effects of NSAIDs on cytokines and transcription factors during the early stages of colorectal cancer. Vivek Vaish, Sankar N. Sanyal (p. 1210) Abstract / Article (PDF format) Dual effects of heparin on BMP-2-induced osteogenic activity in MC3T3-E1 cells. Shin Kanzaki, Wataru Ariyoshi, Tetsu Takahashi, Toshinori Okinaga, Takeshi Kaneuji, Sho Mitsugi, Keisuke Nakashima, Toshiyuki Tsujisawa, Tatsuji Nishihara (p. 1222) Abstract / Article (PDF format) SHORT COMMUNICATIONS Differential effects of glycine on the anticonvulsant activity of D-cycloserine and L-701,324 in mice. Piotr Wlaź, Ewa Poleszak (p. 1231) Abstract / Article (PDF format) Delta opiod receptor contribute to the cardiorespiratory effects of biphalin in anesthetized rats. Piotr Wojciechowski, Małgorzata Szereda-Przestaszewska, Andrzej W. Lipkowski (p. 1235) Abstract / Article (PDF format) Digoxin increases hydrogen sulfide concentrations in brain, heart and kidney tissues in mice. Bogdan Wiliński, Jerzy Wiliński, Eugeniusz Somogyi, Joanna Piotrowska, Marta Góralska (p. 1243) Abstract / Article (PDF format) Influence of ezetimibe monotherapy on ischemia-modified albumin levels in hypercholesterolemic patients. Kazuhiko Kotani, Russell Caccavello, Naoki Sakane, Michiaki Miyamoto, Alejandro Gugliucci (p. 1248) Abstract / Article (PDF format) Comparative effects of short-term and long-term insulin-indiced hypoglycemia on glucose production in the perfused livers of weaned rats. Romir Rodrigues, Kassia P.S. Feitosa, Antonio M. Felisberto-Junior, Helenton C. Barrena, Rui Curi, Roberto B. Bazotte (p. 1252) Abstract / Article (PDF format) Omeprazole does not change the oral bioavailability or pharmacokinetics of vinpocetine in rats. Tomasz Sozański, Jan Magdalan, Małgorzata Trocha, Antoni Szumny, Anna Merwid-Ląd, Wojciech Słupski, Marta Karaźniewicz-Łada, Grzegorz Kiełbowicz, Dorota Ksiądzyna, Adam Szeląg (p. 1258) Abstract / Article (PDF format) Novel variant of CYP2D6*6 is undeleted by a commonly used genotyping procedure. Henrik Berg Rasmussen, Thomas Werge (p. 1264) Abstract / Article (PDF format) Abstracts of the Neurochemical Conference 2011. THE DAYS OF NEUROCHEMISTRY "GENETIC AND MOLECULAR MECHANISMS OF NEUROLOGICAL DISEASES. PROGRESS IN DIAGNOSIS AND THERAPY". (p. 1268) (Title page) Oral communications (p. 1269) Posters (p. 1285)

CONTENTS (PDF format)

Review - Pharmacological activity of Salvinorin A, the major component of Salvia divinorum. Joanna Listos, Alicja Merska, Sylwia Fidecka (p. 1305) Abstract / Article (PDF format) Review - Role of serotonin (5-HT)1B receptors in psychostimulant addiction. Joanna Miszkiel, Małgorzata Filip, Edmund Przegaliński (p. 1310) Abstract / Article (PDF format) Review - Neurogenesis in the epileptic brain: a brief overview from temporal lobe epilepsy. Marta Andres-Mach, John R. Fike, Jarogniew J. Łuszczki (p. 1316) Abstract / Article (PDF format) Review - Kynurenic acid and kynurenine aminotransferases in retinal aging and neurodegeneration. Robert Rejdak, Anselm Junemann, Paweł Grieb, Sebastian Thaler, Frank Schuettauf, Tomasz Chorągiewicz, Tomasz Żarnowski, Waldemar A. Turski, Eberhart Zrenner (p. 1324) Abstract / Article (PDF format) Review - Ezetimibe - A new approach in hypercholesterolemia management. Dariusz Suchy, Krzysztof Łabuzek, Antoni Stadnicki, Bogusław Okopień (p. 1335) Abstract / Article (PDF format) Effects of the noradrenergic neurotoxin DSP-4 on the expression of alpha1-adrenoceptor subtypes after antidepressant treatment. Grzegorz Kreiner, Agnieszka Zelek-Molik, Marta Kowalska, Adam Bielawski, Lucyna Antkiewicz-Michaluk, Irena Nalepa (p. 1349) Abstract / Article (PDF format) GET73 modulates rat hippocampal glutamate transmission: evidence for a functional interaction with mGluR5. Luca Ferraro, Sarah Beggiato, Maria Cristina Tomasini, Tiziana Antonelli, Antonella Loche, Sergio Tanganelli (p. 1359) Abstract / Article (PDF format) Memory-related effects of cholinergic receptor ligands in mice as measured by the elevated plus maze test. Marta Kruk, Kinga Tendera, Grażyna Biała (p. 1372) Abstract / Article (PDF format) Partial lesion of the dopaminergic innervation of the ventral striatum induces "depressive-like" behavior of rats. Katarzyna Kuter, Wacław Kolasiewicz, Krystyna Gołembiowska, Anna Dziubina, Gert Schulze, Klemencja Berghauzen, Jadwiga Wardas, Krystyna Ossowska (p. 1383) Abstract / Article (PDF format) Effect of prior stress on interleukin-1beta and HPA axis responses to acute stress. Anna Gądek-Michalska, Joanna Tadeusz, Paulina Rachwalska, Jadwiga Spyrka, Jan Bugajski (p. 1393) Abstract / Article (PDF format) Imipramine counteracts corticosterone-induced enhancement of glutamatergic transmission and impairment of long-term potentiation in the rat frontal cortex. Bartosz Bobula, Joanna Wabno, Grzegorz Hess (p. 1404) Abstract / Article (PDF format) Investigations on gastroprotective effect of citalopram, an antidepressant drug against stress and pyloric ligation induced ulcers. Bhagawati Saxena, Sanjay Singh (p. 1413) Abstract / Article (PDF format) Modification of local anesthetic-induced antinociception by fentanyl in rats. Tufan Mert, Yasemin Gunes, Dilek Oscengiz (p. 1427) Abstract / Article (PDF format) Paracetamol treatment increases telomerase activity in rat embryonic liver cells. Augustinus Bader, Oliver Petters, Mario Keller, Sanja Pavlica (p. 1435) Abstract / Article (PDF format) Novel I1-imidazoline S43126 enhance insulin action in PC12 cells. Jerusalem Tesfai, Louis Crane, Genevieve Baziard-Mouysset, Wentsworth Kennedy, Lincoln P. Edwards (p. 1442) Abstract / Article (PDF format) Acute myocardial ischemia enhances the vanilloid TRPV1 and serotonin 5-HT3 receptor-mediated Bezold-Jarish reflex in rats. Sebastian Ł. Łupiński, Eberhard Schlicker, Anna Pędzińska-Betiuk, BArbara Malinowska (p. 1450) Abstract / Article (PDF format) Effects of two isomers of DDT and their metabolite DDE on CYP1A1 and AhR function in human placental cells. Anna K. Wójtowicz, Ewelina Honkisz, Dorota Zięba-Przybylska, Tomasz Milewicz, Małgorzata Kajta (p. 1460) Abstract / Article (PDF format) Cytoprotective effects of CSTMP, a novel stilbene derivative, against H2O2-induced oxidative stress in human endothelial cells. Li Zhai, Peng Zhang, Ren_yuan Sun, Xin-Yong Liu, Wei-Guo Liu, Xiu-Li Guo (p. 1469) Abstract / Article (PDF format) Effects of bestatin on phagocytic cells in cyclophosphamide-treated mice. Magdalena Lis, Bożena Obmińska-Mrukowicz (p. 1481) Abstract / Article (PDF format) Effect of neuroleptics on cytochrome P450 2C11 (CYP2C11) in rat liver. Anna Haduch, Jacek Wójcikowski, Władysława A. Daniel (p. 1491) Abstract / Article (PDF format) Oleanolic acid derivative methyl 3,11-dioxoolean-12-en-28-olate targets multidrug resistance related to ABCB1. Anna Paszel, Błażej Rubiś, Barbara Bednarczyk-Cwynar, Lucjusz Zaprutko, Mariusz Kaczmarek, Johann Hofmann, Maria Rybczyńska (p. 1500) Abstract / Article (PDF format) Comparison of the pharmacokinetics of paracetamol from two generic products in patients after total gastric resection. Edyta Szałek, Agnieszka Kamińska, Dawid Murawa, Karol Połom, Bartosz Urbaniak, Matylda Sobiech, Edmund Grześkowiak, Tomasz Grabowski, Anna Wolc, Zenon J. Kokot, Paweł Murawa (p. 1518) Abstract / Article (PDF format) SHORT COMMUNICATIONS NMDA and AMPA receptors are involved in the antidepressant-like activity of tianeptine in the forced swim test in mice. Piotr Wlaź, Regina Kasperek, Aleksandra Wlaź, Michał Szumiło, Andrzej Wróbel, Gabriel Nowak, Ewa Poleszak (p. 1526) Abstract / Article (PDF format) Enhancement of the anti-immobility action of antidepressants by risperidone in the forced swimming test in mice. Zofia Rogóż, Marcin Kabziński (p. 1533) Abstract / Article (PDF format) Different pattern of changes in calcium binding proteins immunoreactivity in the medial prefrontal cortex of rats exposed to stress models of depression. Monika Zadrożna, Barbara Nowak, Magdalena Łasoń-Tyburkiewicz, Małgorzata Wolak, Magdalena Sowa-Kućma, Mariusz Papp, Grażyna Ossowska, Andrzej Pilc, Gabriel Nowak (p. 1539) Abstract / Article (PDF format) Anxiolytic-like effects of olanzapine, risperidone and fluoxetine in the elevated plus-maze test in rats. Zofia Rogóż, Grażyna Skuza (p. 1547) Abstract / Article (PDF format) Effects of the histamine (H)3 receptor antagonist ABT-239 on acute and repeated nicotine locomotor responses in rats. Joanna Miszkiel, Marta Kruk, Andrew C. McCreary, Edmund Przegaliński, Grażyna Biała, Małgorzata Filip (p. 1553) Abstract / Article (PDF format) Low-dose oral caffeine induces a specific form of behavioral sensitization in rats. Kevin T. Ball, Alex Poplawsky (p. 1560) Abstract / Article (PDF format) Effects of PB190 and PB212, new sigma receptor ligands, on glucocorticoid receptor-mediated gene transcription in LMCAT cells. Grażyna Skuza, Magdalena Szymańska, Bogusława Budziszewska, Carmen Abate, Francesco Berardi (p. 1564) Abstract / Article (PDF format) Kynurenic acid: a new effector of valproate action? Piotr Maciejak, Janusz Szyndler, Danuta Turzyńska, Alicja Sobolewska, Adam Płaźnik (p. 1569) Abstract / Article (PDF format) Effects of simvastatin on the pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, after oral and intravenous administration in rats: possible role of P-glycoprotein and CYP3A4 inhibition by simvastatin. Dong Hyun-Choi, Jin-Seok Choi, Cheng Li, Jun-Shik Choi (p. 1574) Abstract / Article (PDF format)