Team II
- Brain microdialysis in rats and mice
- High performance liquid chromatography (HPLC) with electrochemical, coulochemical and fluorescence detection
- Assessment of DNA damage using a comet assay
- Behavioral tests
- Demonstration of antioxidant and anti-inflammatory properties of A2A receptor antagonists as a new, non-dopaminergic treatment in Parkinson's disease.
- Caffeine-induced augmentation of psychostimulant and neurotoxic effects of MDMA (ecstasy) in mice.
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Effect of Psilocybin and Ketamine on Brain Neurotransmitters, Glutamate Receptors, DNA and Rat Behavior.
Adam Wojtas, Agnieszka Bysiek, Agnieszka Wawrzczak-Bargiela, Zuzanna Szych, Iwona Majcher-Maślanka, Monika Herian, Marzena Maćkowiak, Krystyna Gołembiowska
International journal of molecular sciences, 6713 10.3390/ijms23126713
PMID:35743159 -
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Micaela Tirri, Sabrine Bilel, Raffaella Arfè, Giorgia Corli, Beatrice Marchetti, Tatiana Bernardi, Federica Boccuto, Giovanni Serpelloni, Francesco Botrè, Fabio De-Giorgio, Krystyna Golembiowska, Matteo Marti
Frontiers in psychiatry, 10.3389/fpsyt.2022.875722
PMID:35530025 -
Neurotoxicological profile of the hallucinogenic compound 25I-NBOMe.
Monika Herian, Adam Wojtas, Marzena Maćkowiak, Agnieszka Wawrzczak-Bargiela, Anna Solarz, Agnieszka Bysiek, Katarzyna Madej, Krystyna Gołembiowska
Scientific reports, 10.1038/s41598-022-07069-8
PMID:35190675 -
Neurotoxicity of MDMA: Main effects and mechanisms.
Giulia Costa, Krystyna Gołembiowska
Experimental neurology, S0014-4886(21)00302-2 10.1016/j.expneurol.2021.113894
PMID:34655576 -
Tolerance to neurochemical and behavioral effects of the hallucinogen 25I-NBOMe.
Monika Herian, Mateusz Skawski, Adam Wojtas, Małgorzata K Sobocińska, Karolina Noworyta, Krystyna Gołembiowska
Psychopharmacology, 10.1007/s00213-021-05860-5
PMID:34032876 -
Neurochemical and Behavioral Effects of a New Hallucinogenic Compound 25B-NBOMe in Rats.
Adam Wojtas, Monika Herian, Mateusz Skawski, Małgorzata Sobocińska, Alejandro González-Marín, Karolina Noworyta-Sokołowska, Krystyna Gołembiowska
Neurotoxicity research, 10.1007/s12640-020-00297-8
PMID:33337517 -
Contribution of serotonin receptor subtypes to hallucinogenic activity of 25I-NBOMe and to its effect on neurotransmission.
Monika Herian, Adam Wojtas, Małgorzata Katarzyna Sobocińska, Mateusz Skawski, Alejandro González-Marín, Krystyna Gołembiowska
Pharmacological reports : PR, 10.1007/s43440-020-00181-4
PMID:33174181 -
Functional characterization of a novel opioid, PZM21, and its effects on the behavioural responses to morphine.
Lucja Kudla, Ryszard Bugno, Urszula Skupio, Lucja Wiktorowska, Wojciech Solecki, Adam Wojtas, Krystyna Golembiowska, Ferenc Zádor, Sándor Benyhe, Szymon Buda, Wioletta Makuch, Barbara Przewlocka, Andrzej J Bojarski, Ryszard Przewlocki
British journal of pharmacology, 10.1111/bph.14805
PMID:31347704 -
Bioanalytical methodology for determination of glutamate and aspartate for use in pharmacological sciences with application of Integrated Calibration Method.
Paweł Świt, Katarzyna Kamińska, Monika Herian
Talanta, S0039-9140(19)30870-7 10.1016/j.talanta.2019.120237
PMID:31514830 -
Hallucinogen-Like Action of the Novel Designer Drug 25I-NBOMe and Its Effect on Cortical Neurotransmitters in Rats.
Monika Herian, Adam Wojtas, Katarzyna Kamińska, Paweł Świt, Anna Wach, Krystyna Gołembiowska
Neurotoxicity research, 10.1007/s12640-019-00033-x
PMID:30989482 -
Methcathinone and 3-Fluoromethcathinone Stimulate Spontaneous Horizontal Locomotor Activity in Mice and Elevate Extracellular Dopamine and Serotonin Levels in the Mouse Striatum.
Jakub Wojcieszak, Dariusz Andrzejczak, Adam Wojtas, Krystyna Gołembiowska, Jolanta B Zawilska
Neurotoxicity research, 10.1007/s12640-018-9973-4
PMID:30377956 -
Effects of exposure to 5-MeO-DIPT during adolescence on brain neurotransmission and neurotoxicity in adult rats.
Karolina Noworyta-Sokołowska, Katarzyna Kamińska, Joanna Rzemieniec, Agnieszka Wnuk, Jakub Wojcieszak, Anna Maria Górska, Grzegorz Kreiner, Małgorzata Kajta, Krystyna Gołembiowska
Forensic toxicology, 10.1007/s11419-018-0433-x
PMID:30636982 -
The effect of chronic co-treatment with risperidone and novel antidepressant drugs on the dopamine and serotonin levels in the rats frontal cortex.
Katarzyna Kamińska, Anna Górska, Karolina Noworyta-Sokołowska, Adam Wojtas, Zofia Rogóż, Krystyna Gołembiowska
Pharmacological reports : PR, 10.1016/j.pharep.2018.04.009
PMID:32002949 -
The effect of chronic co-treatment with risperidone and novel antidepressant drugs on the dopamine and serotonin levels in the rats frontal cortex.
Katarzyna Kamińska, Anna Górska, Karolina Noworyta-Sokołowska, Adam Wojtas, Zofia Rogóż, Krystyna Gołembiowska
Pharmacological reports : PR, S1734-1140(17)30811-3 10.1016/j.pharep.2018.04.009
PMID:30144663 -
The Effects of Exposure to Mephedrone During Adolescence on Brain Neurotransmission and Neurotoxicity in Adult Rats.
Katarzyna Kamińska, Karolina Noworyta-Sokołowska, Anna Górska, Joanna Rzemieniec, Agnieszka Wnuk, Adam Wojtas, Grzegorz Kreiner, Małgorzata Kajta, Krystyna Gołembiowska
Neurotoxicity research, 10.1007/s12640-018-9908-0
PMID:29713996
- GOŁEMBIOWSKA K.: Pharmacology and Neurotoxicity of 5-MeO-DIPT. In: Kostrzewa R.M. (eds) Handbook of Neurotoxicity. Springer, Cham, 2021, 1-12.
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Effects of Synthetic Cathinones on Brain Neurotransmitters.
GOŁEMBIOWSKA K., KAMIŃSKA K. Effects of Synthetic Cathinones on Brain Neurotransmitters. In: Zawilska J. B. (ed.) Synthetic Cathinones. Current Topics in Neurotoxicity 12. Springer International Publishing AG, Cham, 2018, p. 117-124.
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Tirri Micaela, Bilel Sabrine, Arfè Raffaella, Corli Giorgia, Marchetti Beatrice, Bernardi Tatiana, Boccuto Federica, Serpelloni Giovanni, Botrè Francesco, De-Giorgio Fabio, Golembiowska Krystyna, Marti Mateo. Effect of –NBOMe Compounds on sensorimotor, motor, and prepulse inhibition responses in mice in comparison with the 2C analogs and Lysergic Acid Diethylamide: from preclinical evidence to forensic implication in driving under the influence of drugs. Front. Psychiatry, April 2022, 13, 875722. https://doi.org/10.3389/fpsyt.2022.875722
- GOŁEMBIOWSKA K., KAMIŃSKA K. Effects of Synthetic Cathinones on Brain Neurotransmitters. In: Zawilska J. B. (ed.) Synthetic Cathinones. Current Topics in Neurotoxicity 12. Springer International Publishing AG, Cham, 2018, p. 117-124.
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Neurochemical basis of antidepressive properties of psychedelics in rodent model of depression OPUS 19 2020/37/B/NZ7/03753, Professor Krystyna Gołembiowska, PhD
Neurochemical basis of antidepressive properties of psychedelics in rodent model of depression -
Pharmacological properties and neurotoxicity of novel NBOMe derivatives, Professor Krystyna Gołembiowska, PhD
OPUS11 2016/21/B/NZ7/01131
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, Professor Krystyna Gołembiowska, PhD
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, Professor Krystyna Gołembiowska, PhD
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, Professor Krystyna Gołembiowska, PhD
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, Professor Krystyna Gołembiowska, PhD
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, Professor Krystyna Gołembiowska, PhD
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, Professor Krystyna Gołembiowska, PhD
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, Professor Krystyna Gołembiowska, PhD
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, Professor Krystyna Gołembiowska, PhD
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, Professor Krystyna Gołembiowska, PhD
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, Professor Krystyna Gołembiowska, PhD
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, Professor Krystyna Gołembiowska, PhD
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, Professor Krystyna Gołembiowska, PhD
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, Professor Krystyna Gołembiowska, PhD
interests
techniques
keywords
- adenosine
- adenosine receptors
- amphetamine
- animal models
- antidepressants
- antipsychotics
- anxiolytics
- apoptosis
- behavioural analysis
- chronic schizophrenia
- cognitive functions
- depression
- escitalopram
- excitotoxicity
- frontal cortex
- GABA
- glutamate
- glutamatergic receptors
- MDMA
- memory
- metabotropic glutamate receptors
- mirtazapine
- monoamines
- neurodegeneration
- neuroprotection
- neurotoxicity
- nigro-striatal dopaminergic system
- noradrenaline
- Parkinson's disease
- psychosis
- rat
- risperidone
- schizophrenia
- serotonin
- serotonin receptors
- striatum
- treatment-resistant depression
- working memory