Laboratory of Biochemical Pharmacology


Welcome to the website of the Laboratory of Biochemical Pharmacology. We are part of the Department of Pharmacology, Maj  Institute of Pharmacology, Polish Academy of Sciences in Krakow. Our team consists of people with different educational background, who share a passion to discover the mechanisms of action of drugs. The subject of our preclinical research concerns mechanism of action psychoactive drugs, especially antidepressants and antipsychotics.

Research methods and models used in the our Laboratory are very advanced, diverse and constantly developed - from cell cultures to transgenic animals, from radioisotope techniques (saturation and competition analyzes, receptor autoradiography) to studies of receptor protein interactions in the brain using the PLA technique, in situ hybridization, RT-PCR and miRNA measurements; basically it's hard to list them all.

 

Our strength is an excellent well-coordinated team, interdisciplinary and closely cooperating, which means that no new technique is difficult for us.


More publications
  • 1. Faron-Górecka A, Szafran-Pilch K. (2016) Prolactin and Somatostatin Responses to Antidepressant Therapy. In: López-Muñoz F., Srinivasan V., de Berardis D., Álamo C., Kato T. (eds) Melatonin, Neuroprotective Agents and Antidepressant Therapy. Springer, N


  • Understanding GPCR dimerization. Methods in Cell Biology, Elsevier https://doi.org/10.1016/bs.mcb.2018.08.005

    Faron-Górecka A, Kuśmider M, Solich J, Górecki A, Dziedzicka-Wasylewska M. (2020) Genetic variants in dopamine receptors influence on heterodimerization in the context of antipsychotic drug action. Progress in Molecular Biology and Translational Science, Elsevier  https://doi.org/10.1016/bs.pmbts.2019.11.008

    Faron-Górecka A, Szlachta M, Kolasa M, Solich J, Górecki A, Kuśmider M, Żurawek D, Dziedzicka-Wasylewska M. (2019) Understanding GPCR dimerization. Methods in Cell Biology, Elsevier https://doi.org/10.1016/bs.mcb.2018.08.005

    Faron-Górecka A, Szafran-Pilch K. (2016) Prolactin and Somatostatin Responses to Antidepressant Therapy. In: López-Muñoz F., Srinivasan V., de Berardis D., Álamo C., Kato T. (eds) Melatonin, Neuroprotective Agents and Antidepressant Therapy. Springer, New Delhi 

    Zurawek D., Faron-Górecka A, Kuśmider M, Solich J, Kolasa M, Szafran-Pilch K, Kmiotek K, Gruca P, Papp M, Dziedzicka-Wasylewska M. (2015) Dopamine D1 and D2 Receptors in Chronic Mild Stress: Analysis of Dynamic Receptor Changes in an Animal Model of Depression Using In Situ Hybridization and Autoradiography. In: Tiberi M. (eds) Dopamine Receptor Technologies. Neuromethods, vol 96. Humana Press, New York, NY

    Łukasiewicz S, Faron-Górecka A, Dziedzicka-Wasylewska M. (2013) A Biophysical Approach for the Study of Dopamine Receptor Oligomerization. In: Kabbani N. (eds) Dopamine. Methods in Molecular Biology (Methods and Protocols), vol 964. Humana Press, Totowa, NJ

More publications
  • Molecular mechanism of the unique action of clozapine in the context of heterodimerization of receptors associated with G proteins., Agata Faron - Górecka, PhD
  • Endogenous markers of the effectiveness of depression therapy in the model of chronic mild stress (CMS). , Agata Faron - Górecka, PhD
more_grants
  • FNP scholarship for young scientists (START Program), Agata Faron - Górecka, PhD
    Monday, 30 November -0001
  • FNP scholarship for young scientists (START Program), Agata Faron - Górecka, PhD
    Monday, 30 November -0001
more_awards