Laboratory of Biochemical Pharmacology


Welcome to the website of the Laboratory of Biochemical Pharmacology. We are part of the Department of Pharmacology, Maj  Institute of Pharmacology, Polish Academy of Sciences in Krakow. Our team consists of people with different educational backgrounds, who share a passion for discovering the mechanisms of the action of drugs. The subject of our preclinical research concerns the mechanism of action of psychoactive drugs, especially antidepressants and antipsychotics in the context of drug resistance.

Research methods and models used in our Laboratory are very advanced, diverse, and constantly developed - from cell cultures to transgenic animals, from radioisotope techniques (saturation and competition analyses, receptor autoradiography) to studies of receptor protein interactions in the brain using the PLA technique, in situ hybridization, RT-PCR and miRNA measurements; basically, it's hard to list them all.

 

Our strength is an excellent well-coordinated team, interdisciplinary and closely cooperating, which means that no new technique is difficult for us.


In November 2022, a team has been awarded the Division V of Medical Sciences of the Polish Academy of Sciences for a series of publications: "Determination of the role of selected microRNAs as biomarkers of stress resilience".

More publications
  • 1. Faron-Górecka A, Szafran-Pilch K. (2016) Prolactin and Somatostatin Responses to Antidepressant Therapy. In: López-Muñoz F., Srinivasan V., de Berardis D., Álamo C., Kato T. (eds) Melatonin, Neuroprotective Agents and Antidepressant Therapy. Springer, N


  • Understanding GPCR dimerization. Methods in Cell Biology, Elsevier https://doi.org/10.1016/bs.mcb.2018.08.005

    Faron-Górecka A, Kuśmider M, Solich J, Górecki A, Dziedzicka-Wasylewska M. (2020) Genetic variants in dopamine receptors influence on heterodimerization in the context of antipsychotic drug action. Progress in Molecular Biology and Translational Science, Elsevier  https://doi.org/10.1016/bs.pmbts.2019.11.008

    Faron-Górecka A, Szlachta M, Kolasa M, Solich J, Górecki A, Kuśmider M, Żurawek D, Dziedzicka-Wasylewska M. (2019) Understanding GPCR dimerization. Methods in Cell Biology, Elsevier https://doi.org/10.1016/bs.mcb.2018.08.005

    Faron-Górecka A, Szafran-Pilch K. (2016) Prolactin and Somatostatin Responses to Antidepressant Therapy. In: López-Muñoz F., Srinivasan V., de Berardis D., Álamo C., Kato T. (eds) Melatonin, Neuroprotective Agents and Antidepressant Therapy. Springer, New Delhi 

    Zurawek D., Faron-Górecka A, Kuśmider M, Solich J, Kolasa M, Szafran-Pilch K, Kmiotek K, Gruca P, Papp M, Dziedzicka-Wasylewska M. (2015) Dopamine D1 and D2 Receptors in Chronic Mild Stress: Analysis of Dynamic Receptor Changes in an Animal Model of Depression Using In Situ Hybridization and Autoradiography. In: Tiberi M. (eds) Dopamine Receptor Technologies. Neuromethods, vol 96. Humana Press, New York, NY

    Łukasiewicz S, Faron-Górecka A, Dziedzicka-Wasylewska M. (2013) A Biophysical Approach for the Study of Dopamine Receptor Oligomerization. In: Kabbani N. (eds) Dopamine. Methods in Molecular Biology (Methods and Protocols), vol 964. Humana Press, Totowa, NJ

More publications
  • NCN OPUS 8 Molecular mechanism of the unique action of clozapine in the context of heterodimerization of receptors associated with G proteins., Agata Faron - Górecka, PhD
  • Endogenous markers of the effectiveness of depression therapy in the model of chronic mild stress (CMS). , Agata Faron - Górecka, PhD
  • , Professor Marta Dziedzicka - Wasylewska, PhD
  • , Professor Marta Dziedzicka - Wasylewska, PhD
  • , Professor Marta Dziedzicka - Wasylewska, PhD
  • , Professor Marta Dziedzicka - Wasylewska, PhD
  • , Professor Marta Dziedzicka - Wasylewska, PhD
  • , Professor Marta Dziedzicka - Wasylewska, PhD
  • , Professor Marta Dziedzicka - Wasylewska, PhD
  • , Professor Marta Dziedzicka - Wasylewska, PhD
  • , Professor Marta Dziedzicka - Wasylewska, PhD
more_grants
  • Scientific Award of the Faculty of Medical Sciences of the Polish Academy of Sciences: prof dr hab. Marta Dziedzicka-Wasylewska, dr hab. Agata Faron-Górecka, dr Joanna Solich, Agata Faron - Górecka, PhD
    Thursday, 17 November 2022
  • FNP scholarship for young scientists (START Program), Agata Faron - Górecka, PhD
    Saturday, 26 April 2008
  • FNP scholarship for young scientists (START Program), Agata Faron - Górecka, PhD
    Saturday, 21 April 2007
  • ECNP Travel Award - ECNP Workshop on Neuropsychopharmacology for Young Scientists in Europe, Nicea, France, Agata Faron - Górecka, PhD
    Thursday, 9 March 2006
  • ECNP Travel Award - ECNP Workshop on Neuropsychopharmacology for Young Scientists in Europe, Nicea, France, Agata Faron - Górecka, PhD
    Saturday, 8 March 0200
  • , Professor Marta Dziedzicka - Wasylewska, PhD
    Monday, 30 November -0001
more_awards