Department of Phytochemistry

Our studies are focused on biologically active secondary metabolites from plants and plant tissue cultures, with special interest in compounds biosynthesized by the plants of Cichorieae and Inuleae tribes (Asteraceae family). Recently, we have been investigating formerly unexamined Lactuca species of African and Asian origin, in a search of antioxidative and anti-inflammatory compounds.

Scope of research:

• plant secondary metabolites - isolation and structure identification/elucidation,
• qualitative and quantitative analysis of bioactive compounds in a plant material,
• regulation of plant metabolism in vitro and in vivo,
• bioactivity assays,
• tissue cultures of medicinal plants.

• Thymol derivatives from the roots of Xerolekia speciosissima an endemic species of the pre-Alpine area Kłeczek N., Malarz J., Kosecka-Strojek M., Musielak B., Stojakowska A. 2019. DOI: 10.1016/j.phytol.2019.01.010
• Sesquiterpene lactones and phenolics from roots of Leontodon hispidus subsp. hispidus

  Michalska K., Pieron K., Stojakowska A. 2018. Nat. Prod. Commun., 13, 393-394.

• Phenolics and terpenoids from a wild edible plant Lactuca orientalis (Boiss.) Boiss.: A preliminary study

  Stojakowska A., Michalska K., Kłeczek N., Malarz J., Beharav A. 2018. J. Food Comp. Anal., 69, 20-24.
  

• Bioactive phenolics from in vitro cultures of Lactuca aculeata Boiss. et Kotschy Stojakowska A., Malarz J. 2017. Phytochem. Lett., 19, 7-11
• Sesquiterpenoids from roots of Lactuca sativa var. angustana cv. "Gruener Stern"

  Michalska K., Michalski O., Stojakowska A. 2016. DOI 10.1016/j.phytol.2016.10.023

• Hydroxycinnamates from elecampane (Inula helenium L.) callus culture

  Stojakowska A., Malarz J., Kiss A.K. 2016. Acta Physiol. Plant., 38, 41, DOI 10.1007/s11738-016-2069-y

• Acylated hydroxycinnamic acid glucosides from flowers of Telekia speciosa Stojakowska A., Malarz J., Żylewski M., Kisiel W. 2015. Phytochemistry Lett., 12, 257-261
• Chemical constituents of Lactuca dregeana Michalska K., Kisiel W., Stojakowska A. 2015. Biochem. Syst. Ecol., 59, 302-304.
• Quantitative analysis of sesquiterpene lactones and thymol derivatives in extracts from Telekia speciosa Stojakowska A., Malarz J., Kisiel W. 2015. Phytochemistry Lett., 11, 378-383.
• Variation of sesquiterpene lactone contents in Lactuca georgica natural populations from Armenia Beharav A., Stojakowska A., Ben-David R., Malarz J., Michalska K., Kisiel W. 2015. Genet. Resour. Crop Evol., 62, 431-441.
• Chemical constituents from Lactuca inermis, a wild African species.

  Michalska K., Kisiel W.
  Biochem. Syst. Ecol., 2014, 55, 104-106.

• A new neolignan glucoside from hairy roots of Cichorium intybus Malarz J., Stojakowska A., Szneler E., Kisiel W. 2013. Phytochemistry Lett., 6, 59-61
• Phenolic constituents of Lactuca tenerrima Michalska K., Stojakowska A., Kisiel W. 2012. Biochem. Syst. Ecol., 42, 32-34.
• Terpenoids from a multiple shoot culture of Telekia speciosa Stojakowska A., Malarz J., Kisiel W. 2011. Acta Soc. Bot. Pol., 80, 253-256.
• Caffeic acid derivatives from a hairy root culture of Lactuca virosa Stojakowska A., Malarz J., Szewczyk A., Kisiel W. 2012. Acta Physiol. Plant., 34, 291-298.