Department of Phytochemistry


Our studies are focused on biologically active secondary metabolites from plants and plant tissue cultures, with special interest in compounds biosynthesized by the plants of Cichorieae and Inuleae tribes (Asteraceae family). Recently, we have been investigating formerly unexamined Lactuca species of African and Asian origin, in a search of antioxidative and anti-inflammatory compounds.

 

 

Scope of research:

 

  • plant secondary metabolites - isolation and structure identification/elucidation,
  • qualitative and quantitative analysis of bioactive compounds in a plant material,
  • regulation of plant metabolism in vitro and in vivo,
  • bioactivity assays,
  • tissue cultures of medicinal plants.

 

 

In cooperation with other research teams and institutions we perform analyses of selected compounds in a plant material of different origin, provide pure compounds for bioactivity evaluation and share plant materials for biological studies.
more_publications
  • Bioactive phenolics from in vitro cultures of Lactuca aculeata Boiss. et Kotschy Stojakowska A., Malarz J. 2017. Phytochem. Lett., 19, 7-11
  • Sesquiterpenoids from roots of Lactuca sativa var. angustana cv. "Gruener Stern"

    Michalska K., Michalski O., Stojakowska A. 2016. DOI 10.1016/j.phytol.2016.10.023

  • Hydroxycinnamates from elecampane (Inula helenium L.) callus culture

    Stojakowska A., Malarz J., Kiss A.K. 2016. Acta Physiol. Plant., 38, 41, DOI 10.1007/s11738-016-2069-y

  • Acylated hydroxycinnamic acid glucosides from flowers of Telekia speciosa Stojakowska A., Malarz J., Żylewski M., Kisiel W. 2015. Phytochemistry Lett., 12, 257-261
  • Chemical constituents of Lactuca dregeana Michalska K., Kisiel W., Stojakowska A. 2015. Biochem. Syst. Ecol., 59, 302-304.
  • Quantitative analysis of sesquiterpene lactones and thymol derivatives in extracts from Telekia speciosa Stojakowska A., Malarz J., Kisiel W. 2015. Phytochemistry Lett., 11, 378-383.
  • Variation of sesquiterpene lactone contents in Lactuca georgica natural populations from Armenia Beharav A., Stojakowska A., Ben-David R., Malarz J., Michalska K., Kisiel W. 2015. Genet. Resour. Crop Evol., 62, 431-441.
  • Chemical constituents from Lactuca inermis, a wild African species.

    Michalska K., Kisiel W.
    Biochem. Syst. Ecol., 2014, 55, 104-106.

  • A new neolignan glucoside from hairy roots of Cichorium intybus Malarz J., Stojakowska A., Szneler E., Kisiel W. 2013. Phytochemistry Lett., 6, 59-61
  • Phenolic constituents of Lactuca tenerrima Michalska K., Stojakowska A., Kisiel W. 2012. Biochem. Syst. Ecol., 42, 32-34.
  • Terpenoids from a multiple shoot culture of Telekia speciosa Stojakowska A., Malarz J., Kisiel W. 2011. Acta Soc. Bot. Pol., 80, 253-256.
  • Caffeic acid derivatives from a hairy root culture of Lactuca virosa Stojakowska A., Malarz J., Szewczyk A., Kisiel W. 2012. Acta Physiol. Plant., 34, 291-298.
  • Variation of sesquiterpene lactones in Lactuca aculeata natural populations from Israel, Jordan and Turkey Beharav A., Ben-David R., Malarz J., Stojakowska A., Michalska K., Dolezalova I., Lebeda A., Kisiel W. 2010. Biochem. Syst. Ecol., 38, 602-611.
  • Terpenoids and phenolics from Inula ensifolia Stojakowska A., Malarz J., Zubek S., Turnau K., Kisiel W. 2010. Biochem. Syst. Ecol., 38, 232-235.
  • Interactions between mycorrhizal fungi and medicinal plants Zubek S., Stojakowska A., Kisiel W., Góralska K., Turnau K. 2009. In: Crop Plant Resistance to Biotic and Abiotic Factors: Current Potential and Future Demands. Feldman F., Alford D.V., Furk C. (Eds.). Deutsche Phytomedizinische Gesellschaft, Braunschweig, pp. 124-129
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