Department of Phytochemistry

Our studies are focused on biologically active secondary metabolites from plants and plant tissue cultures, with special interest in compounds biosynthesized by the plants of Cichorieae and Inuleae tribes (Asteraceae family). Recently, we have been investigating formerly unexamined Lactuca species of African and Asian origin, in a search of antioxidative and anti-inflammatory compounds.

 

 

Scope of research:

 

  • plant secondary metabolites - isolation and structure identification/elucidation,
  • qualitative and quantitative analysis of bioactive compounds in a plant material,
  • regulation of plant metabolism in vitro and in vivo,
  • bioactivity assays,
  • tissue cultures of medicinal plants.

 

 

In cooperation with other research teams and institutions we perform analyses of selected compounds in a plant material of different origin, provide pure compounds for bioactivity evaluation and share plant materials for biological studies.
More publications
  • Natural products from Tolpis barbata (L.) Gaertn. (Asteraceae,Cichorieae)

    Michalska K., Malarz J., Paul W., Stojakowska A. Biochem. Syst. Ecol., 2019, 86, 103922
  • Associations between root-inhabiting fungi and 40 species of medicinal plants with potential applications in the pharmaceutical and biotechnological industries Piszczek P., Kuszewska K., Błaszkowski J., Sochacka-Obruśnik A., Stojakowska A., Zubek S. Appl. Soil Ecol., 2019, 137, 69-77
  • Further sesquiterpenoids and phenolics from two species of Taraxacum F.H.Wigg. and cytotoxic activity of taraxinic acid and its derivatives

    Michalska K., Galanty A., Michalski O., Stojakowska A. Phytochem. Lett., 2019, 30, 296-301
  • Thymol derivatives from the roots of Xerolekia speciosissima an endemic species of the pre-Alpine area Kłeczek N., Malarz J., Kosecka-Strojek M., Musielak B., Stojakowska A. 2019, 30, 235-237. DOI: 10.1016/j.phytol.2019.01.010
  • Sesquiterpene lactones and phenolics from roots of Leontodon hispidus subsp. hispidus

    Michalska K., Pieron K., Stojakowska A. 2018. Nat. Prod. Commun., 13, 393-394.
  • Phenolics and terpenoids from a wild edible plant Lactuca orientalis (Boiss.) Boiss.: A preliminary study

    Stojakowska A., Michalska K., Kłeczek N., Malarz J., Beharav A. 2018. J. Food Comp. Anal., 69, 20-24.
  • Bioactive phenolics from in vitro cultures of Lactuca aculeata Boiss. et Kotschy Stojakowska A., Malarz J. 2017. Phytochem. Lett., 19, 7-11
  • Sesquiterpenoids from roots of Lactuca sativa var. angustana cv. "Gruener Stern"

    Michalska K., Michalski O., Stojakowska A. 2017, 20, 425-428. DOI 10.1016/j.phytol.2016.10.023

  • Hydroxycinnamates from elecampane (Inula helenium L.) callus culture

    Stojakowska A., Malarz J., Kiss A.K. 2016. Acta Physiol. Plant., 38, 41, DOI 10.1007/s11738-016-2069-y
  • Acylated hydroxycinnamic acid glucosides from flowers of Telekia speciosa Stojakowska A., Malarz J., Żylewski M., Kisiel W. 2015. Phytochemistry Lett., 12, 257-261
  • Chemical constituents of Lactuca dregeana Michalska K., Kisiel W., Stojakowska A. 2015. Biochem. Syst. Ecol., 59, 302-304.
  • Quantitative analysis of sesquiterpene lactones and thymol derivatives in extracts from Telekia speciosa Stojakowska A., Malarz J., Kisiel W. 2015. Phytochemistry Lett., 11, 378-383.
  • Variation of sesquiterpene lactone contents in Lactuca georgica natural populations from Armenia Beharav A., Stojakowska A., Ben-David R., Malarz J., Michalska K., Kisiel W. 2015. Genet. Resour. Crop Evol., 62, 431-441.
  • Chemical constituents from Lactuca inermis, a wild African species.

    Michalska K., Kisiel W.
    Biochem. Syst. Ecol., 2014, 55, 104-106.

  • A new neolignan glucoside from hairy roots of Cichorium intybus Malarz J., Stojakowska A., Szneler E., Kisiel W. 2013. Phytochemistry Lett., 6, 59-61
More publications
  • The influence of the serotonergic system on the regulation of liver CYP activity in hepatocellular carcinoma, Marta Kot, PhD

  • Sonata 4 2012/07/D/NZ4/00814, Marta Kot, PhD

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Head

Anna Stojakowska, PhD

Phone number: +48 12 6623254
E-mail: stoja@if-pan.krakow.pl

interests

techniques

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