Department of Pharmacology


The Department of Pharmacology includes:

Laboratory of Pharmacology and Brain Biostructure

Laboratory of Behavioral Pharmacology

Laboratory of Biochemical Pharmacology

Affective Cognitive Neuroscience Laboratory

Team I

Team II

More publications
  • A popular-science article "From birth to old age - amorfrutin B in neuroprotection" Karolina Przepiórska

    Link to the article
  • GOŁEMBIOWSKA K.: Pharmacology and Neurotoxicity of 5-MeO-DIPT. In: Kostrzewa R.M. (eds) Handbook of Neurotoxicity. Springer, Cham, 2021, 1-12. 


  • Popular science article "Sunscreen cream - friend or foe?" Agnieszka Wnuk

    Link to the article
  • In search of new therapeutic strategies for the treatment of hypoxia-ischemia-induced brain damages. An article in Polish.

    NAUKA, 2016, 3:55-73. Kajta M, Rzemieniec J, Rużyłło W.

  • Neurobiology of optimism (article in polish) The article was published in journal "Wszechświat" and is based on a talk given during the 2014 Brain Awarness Week in Krakow.

    http://www.ptpk.org/tydzien_mozgu/tydzien_mozgu_2014.html#art_5
  • How hormonally active environmental contaminants affect the brain? An article in Polish. Wszechświat, 2012, 113:10-13. Kajta M.
  • Molecular mechanisms of estrogen action in the central nervous system. An article in Polish. Chapter in the script: Cellular signaling pathways. Edited by I. Nalepa. XXI Zimowa Szkoła Instytutu Farmakologii PAN. Mogilany, 2004, 61-69. Kajta M.
  • Neuronal cell cultures. An article in Polish. Chapter XVII in the book: Cell and Tissue Cultures. Edited by S. Stokłosowa. PWN, Warszawa, 2004, 277-290. Kajta M.
  • 1. Faron-Górecka A, Szafran-Pilch K. (2016) Prolactin and Somatostatin Responses to Antidepressant Therapy. In: López-Muñoz F., Srinivasan V., de Berardis D., Álamo C., Kato T. (eds) Melatonin, Neuroprotective Agents and Antidepressant Therapy. Springer, N


  • Understanding GPCR dimerization. Methods in Cell Biology, Elsevier https://doi.org/10.1016/bs.mcb.2018.08.005

    Faron-Górecka A, Kuśmider M, Solich J, Górecki A, Dziedzicka-Wasylewska M. (2020) Genetic variants in dopamine receptors influence on heterodimerization in the context of antipsychotic drug action. Progress in Molecular Biology and Translational Science, Elsevier  https://doi.org/10.1016/bs.pmbts.2019.11.008

    Faron-Górecka A, Szlachta M, Kolasa M, Solich J, Górecki A, Kuśmider M, Żurawek D, Dziedzicka-Wasylewska M. (2019) Understanding GPCR dimerization. Methods in Cell Biology, Elsevier https://doi.org/10.1016/bs.mcb.2018.08.005

    Faron-Górecka A, Szafran-Pilch K. (2016) Prolactin and Somatostatin Responses to Antidepressant Therapy. In: López-Muñoz F., Srinivasan V., de Berardis D., Álamo C., Kato T. (eds) Melatonin, Neuroprotective Agents and Antidepressant Therapy. Springer, New Delhi 

    Zurawek D., Faron-Górecka A, Kuśmider M, Solich J, Kolasa M, Szafran-Pilch K, Kmiotek K, Gruca P, Papp M, Dziedzicka-Wasylewska M. (2015) Dopamine D1 and D2 Receptors in Chronic Mild Stress: Analysis of Dynamic Receptor Changes in an Animal Model of Depression Using In Situ Hybridization and Autoradiography. In: Tiberi M. (eds) Dopamine Receptor Technologies. Neuromethods, vol 96. Humana Press, New York, NY

    Łukasiewicz S, Faron-Górecka A, Dziedzicka-Wasylewska M. (2013) A Biophysical Approach for the Study of Dopamine Receptor Oligomerization. In: Kabbani N. (eds) Dopamine. Methods in Molecular Biology (Methods and Protocols), vol 964. Humana Press, Totowa, NJ
  • Effects of Synthetic Cathinones on Brain Neurotransmitters.

    GOŁEMBIOWSKA K., KAMIŃSKA K. Effects of Synthetic Cathinones on Brain Neurotransmitters. In: Zawilska J. B. (ed.) Synthetic Cathinones. Current Topics in Neurotoxicity 12. Springer International Publishing AG, Cham, 2018, p. 117-124.

  •       Tirri Micaela, Bilel Sabrine, Arfè Raffaella, Corli Giorgia, Marchetti Beatrice, Bernardi Tatiana, Boccuto Federica, Serpelloni Giovanni, Botrè Francesco, De-Giorgio Fabio, Golembiowska Krystyna, Marti Mateo. Effect of –NBOMe Compounds on sensorimotor, motor, and prepulse inhibition responses in mice in comparison with the 2C analogs and Lysergic Acid Diethylamide: from preclinical evidence to forensic implication in driving under the influence of drugs. Front. Psychiatry, April 2022, 13, 875722. https://doi.org/10.3389/fpsyt.2022.875722
  • GOŁEMBIOWSKA K., KAMIŃSKA K. Effects of Synthetic Cathinones on Brain Neurotransmitters. In: Zawilska J. B. (ed.) Synthetic Cathinones. Current Topics in Neurotoxicity 12. Springer International Publishing AG, Cham, 2018, p. 117-124. 
More publications
  • Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian brain cells, Bernadeta Pietrzak-Wawrzyńska, MSc
    NCN PRELUDIUM Grant; 2023/49/N/NZ7/03640 Principal Investigator of the project: Bernadeta A. Pietrzak-Wawrzyńska, MSc, The Scientific Supervisor of the project: Professor Małgorzata Kajta 
  • Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer’s disease, Karolina Przepiórska-Drońska, MSc
    NCN PRELUDIUM Grant; 2022/45/N/NZ7/01418; 2023-2026. Ongoing.
    Principal Investigator of the grant: Karolina PrzepiórskaThe scientific supervisor of the grant: Professor Małgorzata Kajta
  • Translational and interdisciplinary investigation of phenotypes of reinforcement sensitivity as predictors of the response to antidepressant treatment, Professor Rafał Ryguła, PhD
    Why do antidepressant drugs fail to work in some people suffering from depression, while for others they quickly bring relief of their symptoms? Are the positive outcomes of antidepressant treatment associated with sensitivity to reward and punishment? And if so, could screening of this sensitivity facilitate finding of the right treatment? Although the relationship between reinforcement sensitivity, affective disorders, and effectivity of pharmacological treatment has been widely postulated and brought together through influential theoretical narratives, until now, there has been no systematic study aimed at investigating these interactions. To address this need, in the present project, we will employ a novel animal model linking various levels of sensitivity to reward and punishment with a putative reactivity to antidepressant treatment. We will also compare the obtained results from animals with the data from humans taking antidepressant medications, using the pioneering online techniques and fully translational behavioural tests. Finally, we will verify, compare, and extend the results from animals and humans using computational modelling of behaviour. Based on the proposed experiments we will be able to conduct complex and multilevel verification of the hypothesis that trait sensitivity to reward and punishment (phenotype of reinforcement sensitivity) can determine the interindividual differences in the effectiveness of antidepressant treatment. Obtained results will be used to understand the phenomena of drug resistance and low effectiveness in antidepressant therapy.
  • New post-treatment strategy against stroke and perinatal asphyxia – a novel approach based on a selective activation of membrane estrogen receptors mERα and mERβ, Agnieszka Wnuk, , Agnieszka Wnuk, PhD
    NCN SONATA Grant; 2021/43/D/NZ7/00633; 2022-2025. Ongoing.Principal Investigator of the grant: Agnieszka Wnuk, PhD
  • Selective activation of non-nuclear Estrogen Receptor signaling with PaPE-1 as a novel therapeutic approach for sporadic Alzheimer’s Disease, Professor Małgorzata Kajta, PhD
    NCN OPUS Grant; 2020/39/B/NZ7/00974; 2021-2024. Ongoing.
    Principal Investigator of the grant: Małgorzata Kajta
  • Neurochemical basis of antidepressive properties of psychedelics in rodent model of depression OPUS 19 2020/37/B/NZ7/03753, Professor Krystyna Gołembiowska, PhD
    Neurochemical basis of antidepressive properties of psychedelics in rodent model of depression
  • #Webimmunization. How can online social networks create collective resilience against misinformation?”, Professor Rafał Ryguła, PhD

  • The role of cognitive bias in individual vulnerability to to the transition from controlled use to uncontrolled abuse of alcohol in an animal model., Professor Rafał Ryguła, PhD

  • Searching for effective strategies to protect neuronal cells against hypoxia and ischemia: Identification of neuroprotective mechanisms of the new ligands of AhR and PPARg in experimental models of stroke, Professor Małgorzata Kajta, PhD
    NCN OPUS Grant; 2018/31/B/NZ7/01815; 2019-2022. Ongoing.Principal Investigator of the grant: Małgorzata Kajta
  • Neuroscience boat, Professor Rafał Ryguła, PhD

  • , Professor Rafał Ryguła, PhD

  • Pharmacological and optogenetic investigation of the mechanism of action of Deep Brain Stimulation of the ventromedial prefrontal cortex in an animal model of treatmentresistant depression, Professor Mariusz Papp, PhD
    NCN grant no: 2017/25/B/NZ7/02710
  • The role of endoplasmic reticulum stress in the pathomechanisms of early-life stressinduced dysfunction of the prefronatal cortex and in the mechanisms of action of fluoxetine in children and adolescents, Agnieszka Chocyk, PhD

  • Sensitivity to negative feedback as a cognitive biomarker of depression in an animal model, Professor Rafał Ryguła, PhD
    Carried out in years 2017 - 2020. Received from Polish National Science Centre as a part of OPUS 12 program. P.I.: Rafal Rygula
  • Impact of early-life stress on maturation, permeability of blood brain-barrier and neuroinflammatory processes activation during ontogenetic development , Anna Solarz-Andrzejewska, PhD
    Preludium 12 2016/23/N/NZ4/01148 - kierownik
more_grants
  • Scientific Award of the Faculty of Medical Sciences of the Polish Academy of Sciences: prof dr hab. Marta Dziedzicka-Wasylewska, dr hab. Agata Faron-Górecka, dr Joanna Solich, Agata Faron - Górecka, PhD
    Thursday, 17 November 2022
  • The first place in the competition for a popular-science article "From birth to old age - amorfrutin B in neuroprotection" - the Organizer: board of Directors of the Maj Institute of Pharmacology of the Polish Academy of Sciences., Karolina Przepiórska-Drońska, MSc
    Thursday, 30 September 2021
  • Team Award of the V Faculty of Medical Sciences of the Polish Academy of Sciences for a series of publications., Agnieszka Wnuk, PhD
    Thursday, 22 November 2018
  • A Team Award of the V Faculty of Medical Sciences of the Polish Academy of Sciences for a series of publications. , Professor Małgorzata Kajta, PhD
    Thursday, 22 November 2018
  • Stipends START 2018 granted by The Foundation for Polish Science (FNP) stipends for the young scientists, Agnieszka Wnuk, PhD
    Saturday, 26 May 2018
  • The second place in the competition for a popular-science article "Sunscreen cream - friend or foe?"- the Organizer: Directorate of the IF PAS in Krakow , Agnieszka Wnuk, PhD
    Wednesday, 15 November 2017
  • Rafal Rygula: Prime Minister's award for habilitation, Professor Rafał Ryguła, PhD
    Thursday, 24 November 2016
  • FNP scholarship for young scientists (START Program), Agata Faron - Górecka, PhD
    Saturday, 26 April 2008
  • FNP scholarship for young scientists (START Program), Agata Faron - Górecka, PhD
    Saturday, 21 April 2007
  • ECNP Travel Award - ECNP Workshop on Neuropsychopharmacology for Young Scientists in Europe, Nicea, France, Agata Faron - Górecka, PhD
    Thursday, 9 March 2006
  • J. J. Supniewski Foundation award for scientific achievements., Professor Małgorzata Kajta, PhD
    Wednesday, 25 February 2004
  • ECNP Travel Award - ECNP Workshop on Neuropsychopharmacology for Young Scientists in Europe, Nicea, France, Agata Faron - Górecka, PhD
    Saturday, 8 March 0200
  • , Professor Marta Dziedzicka - Wasylewska, PhD
    Monday, 30 November -0001
more_awards
Head

Professor Mariusz Papp, PhD

Phone number: +48 12 6623352
E-mail: nfpapp@cyfronet.pl

interests

techniques

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