Publications

Dual Alleviation of Acute and Neuropathic Pain by Fused Opioid Agonist-Neurokinin 1 Antagonist Peptidomimetics. Cecilia Betti, Joanna Starnowska, Joanna Mika, Jolanta Dyniewicz, Lukasz Frankiewicz, Alexandre Novoa, Marta Bochynska, Attila Keresztes, Piotr Kosson, Wioletta Makuch, Joost Van Duppen, Nga N Chung, Jozef Vanden Broeck, Andrzej W Lipkowski, Peter W Schiller, Frans Janssens, Marc Ceusters, François Sommen, Theo Meert, Barbara Przewlocka, Dirk Tourwé, Steven Ballet
ACS medicinal chemistry letters, 10.1021/acsmedchemlett.5b00359
PMID:26713106
Tuesday, 29 December 2015
Blockade of Toll-Like Receptors (TLR2, TLR4) Attenuates Pain and Potentiates Buprenorphine Analgesia in a Rat Neuropathic Pain Model. Agnieszka M Jurga, Ewelina Rojewska, Anna Piotrowska, Wioletta Makuch, Dominika Pilat, Barbara Przewlocka, Joanna Mika
Neural plasticity, 10.1155/2016/5238730
PMID:26962463
Tuesday, 29 December 2015
IL-1 receptor antagonist improves morphine and buprenorphine efficacy in a rat neuropathic pain model. Dominika Pilat, Ewelina Rojewska, Agnieszka M Jurga, Anna Piotrowska, Wioletta Makuch, Barbara Przewlocka, Joanna Mika
European journal of pharmacology, 10.1016/j.ejphar.2015.05.058 S0014-2999(15)30056-X
PMID:26043968
Friday, 9 October 2015
PD98059 Influences Immune Factors and Enhances Opioid Analgesia in Model of Neuropathy. Ewelina Rojewska, Katarzyna Popiolek-Barczyk, Natalia Kolosowska, Anna Piotrowska, Magdalena Zychowska, Wioletta Makuch, Barbara Przewlocka, Joanna Mika
PloS one, 10.1371/journal.pone.0138583
PMID:26426693
Friday, 2 October 2015
Beneficial properties of maraviroc on neuropathic pain development and opioid effectiveness in rats. Klaudia Kwiatkowski, Anna Piotrowska, Ewelina Rojewska, Wioletta Makuch, Agnieszka Jurga, Joanna Slusarczyk, Ewa Trojan, Agnieszka Basta-Kaim, Joanna Mika
Progress in neuro-psychopharmacology & biological psychiatry, 10.1016/j.pnpbp.2015.07.005 S0278-5846(15)30013-0
PMID:26190414
Thursday, 16 July 2015
Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy. Katarzyna Popiolek-Barczyk, Natalia Kolosowska, Anna Piotrowska, Wioletta Makuch, Ewelina Rojewska, Agnieszka M Jurga, Dominika Pilat, Joanna Mika
Neural plasticity, 10.1155/2015/676473
PMID:26090236
Friday, 19 June 2015
A multi-target approach for pain treatment: dual inhibition of fatty acid amide hydrolase and TRPV1 in a rat model of osteoarthritis. Natalia Malek, Monika Mrugala, Wioletta Makuch, Natalia Kolosowska, Barbara Przewlocka, Marcin Binkowski, Martyna Czaja, Enrico Morera, Vincenzo Di Marzo, Katarzyna Starowicz
Pain, 10.1097/j.pain.0000000000000132
PMID:25719612
Saturday, 18 April 2015
Effects of chronic doxepin and amitriptyline administration in naïve mice and in neuropathic pain mice model. J Mika, A M Jurga, J Starnowska, M Wasylewski, E Rojewska, W Makuch, K Kwiatkowski, N Malek, B Przewlocka
Neuroscience, 10.1016/j.neuroscience.2015.03.003 S0306-4522(15)00214-6
PMID:25769941
Monday, 13 April 2015
Synthesis and biological evaluation of compact, conformationally constrained bifunctional opioid agonist - neurokinin-1 antagonist peptidomimetics. Karel Guillemyn, Patrycia Kleczkowska, Anna Lesniak, Jolanta Dyniewicz, Olivier Van der Poorten, Isabelle Van den Eynde, Attila Keresztes, Eva Varga, Josephine Lai, Frank Porreca, Nga N Chung, Carole Lemieux, Joanna Mika, Ewelina Rojewska, Wioletta Makuch, Joost Van Duppen, Barbara Przewlocka, Jozef Vanden Broeck, Andrzej W Lipkowski, Peter W Schiller, Dirk Tourwé, Steven Ballet
European journal of medicinal chemistry, 10.1016/j.ejmech.2014.12.033 S0223-5234(14)01142-8
PMID:25544687
Friday, 20 February 2015
The influence of microglia activation on the efficacy of amitriptyline, doxepin, milnacipran, venlafaxine and fluoxetine in a rat model of neuropathic pain. Magdalena Zychowska, Ewelina Rojewska, Wioletta Makuch, Barbara Przewlocka, Joanna Mika
European journal of pharmacology, 10.1016/j.ejphar.2014.11.022 S0014-2999(14)00803-6
PMID:25460025
Monday, 16 February 2015