Publications


Analgesic Properties of Opioid/NK1 Multitarget Ligands with Distinct in Vitro Profiles in Naive and Chronic Constriction Injury Mice. Joanna Starnowska, Roberto Costante, Karel Guillemyn, Katarzyna Popiolek-Barczyk, Nga N Chung, Carole Lemieux, Attila Keresztes, Joost Van Duppen, Adriano Mollica, John Streicher, Jozef Vanden Broeck, Peter W Schiller, Dirk Tourwé, Joanna Mika, Steven Ballet, Barbara Przewlocka
ACS chemical neuroscience, 10.1021/acschemneuro.7b00226
PMID:28699350

Wednesday, 26 July 2017
Bifunctional opioid/nociceptin hybrid KGNOP1 effectively attenuates pain-related behaviour in a rat model of neuropathy. Joanna Starnowska, Karel Guillemyn, Wioletta Makuch, Joanna Mika, Steven Ballet, Barbara Przewlocka
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, S0928-0987(17)30164-1 10.1016/j.ejps.2017.03.029
PMID:28347772

Friday, 24 March 2017
Microglial Inhibition Influences XCL1/XCR1 Expression and Causes Analgesic Effects in a Mouse Model of Diabetic Neuropathy. Magdalena Zychowska, Ewelina Rojewska, Anna Piotrowska, Grzegorz Kreiner, Joanna Mika
Anesthesiology, 10.1097/ALN.0000000000001219
PMID:27387353

Wednesday, 17 August 2016
Maraviroc reduces neuropathic pain through polarization of microglia and astroglia - Evidence from in vivo and in vitro studies. Anna Piotrowska, Klaudia Kwiatkowski, Ewelina Rojewska, Wioletta Makuch, Joanna Mika
Neuropharmacology, 10.1016/j.neuropharm.2016.04.024 S0028-3908(16)30164-2
PMID:27117708

Saturday, 18 June 2016
Direct and indirect pharmacological modulation of CCL2/CCR2 pathway results in attenuation of neuropathic pain - In vivo and in vitro evidence. Anna Piotrowska, Klaudia Kwiatkowski, Ewelina Rojewska, Joanna Slusarczyk, Wioletta Makuch, Agnieszka Basta-Kaim, Barbara Przewlocka, Joanna Mika
Journal of neuroimmunology, 10.1016/j.jneuroim.2016.04.017 S0165-5728(16)30095-9
PMID:27397071

Tuesday, 3 May 2016
Bifunctional Peptide-Based Opioid Agonist-Nociceptin Antagonist Ligands for Dual Treatment of Acute and Neuropathic Pain. Karel Guillemyn, Joanna Starnowska, Camille Lagard, Jolanta Dyniewicz, Ewelina Rojewska, Joanna Mika, Nga N Chung, Valérie Utard, Piotr Kosson, Andrzej W Lipkowski, Lucie Chevillard, Pol Arranz-Gibert, Meritxell Teixidó, Bruno Megarbane, Dirk Tourwé, Frédéric Simonin, Barbara Przewlocka, Peter W Schiller, Steven Ballet
Journal of medicinal chemistry, 10.1021/acs.jmedchem.5b01976
PMID:27035422

Thursday, 14 April 2016
Blockade of Toll-Like Receptors (TLR2, TLR4) Attenuates Pain and Potentiates Buprenorphine Analgesia in a Rat Neuropathic Pain Model. Agnieszka M Jurga, Ewelina Rojewska, Anna Piotrowska, Wioletta Makuch, Dominika Pilat, Barbara Przewlocka, Joanna Mika
Neural plasticity, 10.1155/2016/5238730
PMID:26962463

Thursday, 10 March 2016
Anti-inflammatory properties of tianeptine on lipopolysaccharide-induced changes in microglial cells involve toll-like receptor-related pathways. Joanna Slusarczyk, Ewa Trojan, Katarzyna Glombik, Anna Piotrowska, Boguslawa Budziszewska, Marta Kubera, Katarzyna Popiolek-Barczyk, Wladyslaw Lason, Joanna Mika, Agnieszka Basta-Kaim
Journal of neurochemistry, 10.1111/jnc.13452
PMID:26640965

Monday, 15 February 2016
Blockade of IL-18 signaling diminished neuropathic pain and enhanced the efficacy of morphine and buprenorphine. Dominika Pilat, Anna Piotrowska, Ewelina Rojewska, Agnieszka Jurga, Joanna Ślusarczyk, Wioletta Makuch, Agnieszka Basta-Kaim, Barbara Przewlocka, Joanna Mika
Molecular and cellular neurosciences, 10.1016/j.mcn.2015.12.013 S1044-7431(15)30053-1
PMID:26763728

Tuesday, 5 January 2016
Pharmacological kynurenine 3-monooxygenase enzyme inhibition significantly reduces neuropathic pain in a rat model. Ewelina Rojewska, Anna Piotrowska, Wioletta Makuch, Barbara Przewlocka, Joanna Mika
Neuropharmacology, 10.1016/j.neuropharm.2015.10.040 S0028-3908(15)30163-5
PMID:26524415

Sunday, 3 January 2016