Publications


Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents. Tomasz Stefański, Renata Mikstacka, Rafał Kurczab, Zbigniew Dutkiewicz, Małgorzata Kucińska, Marek Murias, Małgorzata Zielińska-Przyjemska, Michał Cichocki, Anna Teubert, Mariusz Kaczmarek, Adam Hogendorf, Stanisław Sobiak
European journal of medicinal chemistry, S0223-5234(17)30953-4 10.1016/j.ejmech.2017.11.050
PMID:29291446

Tuesday, 12 December 2017
The Effect of Carboxamide/Sulfonamide Replacement in Arylpiperazinylalkyl Derivatives on Activity to Serotonin and Dopamine Receptors. Piotr Kowalski, Paweł Śliwa, Grzegorz Satała, Rafał Kurczab, Ilona Bartos, Karol Zuchowicz
Archiv der Pharmazie, 10.1002/ardp.201700090
PMID:28846141

Monday, 28 August 2017
Lactose esters: synthesis and biotechnological applications. Jakub Staroń, Janusz M Dąbrowski, Ewelina Cichoń, Maciej Guzik
Critical reviews in biotechnology, 10.1080/07388551.2017.1332571
PMID:28585445

Tuesday, 6 June 2017
Reaction mechanism of sterol hydroxylation by steroid C25 dehydrogenase - Homology model, reactivity and isoenzymatic diversity. Agnieszka Rugor, Anna Wójcik-Augustyn, Ewa Niedzialkowska, Stefan Mordalski, Jakub Staroń, Andrzej Bojarski, Maciej Szaleniec
Journal of inorganic biochemistry, S0162-0134(17)30009-0 10.1016/j.jinorgbio.2017.04.027
PMID:28482186

Monday, 8 May 2017
Low-basicity 5-HT7 Receptor Agonists Synthesized Using the van Leusen Multicomponent Protocol. Adam S Hogendorf, Agata Hogendorf, Rafał Kurczab, Grzegorz Satała, Tomasz Lenda, Maria Walczak, Gniewomir Latacz, Jadwiga Handzlik, Katarzyna Kieć-Kononowicz, Joanna M Wierońska, Monika Woźniak, Paulina Cieślik, Ryszard Bugno, Jakub Staroń, Andrzej J Bojarski
Scientific reports, 10.1038/s41598-017-00822-4
PMID:28473721

Thursday, 4 May 2017
The impact of the halogen bonding on D2 and 5-HT1A/5-HT7 receptor activity of azinesulfonamides of 4-[(2-ethyl)piperidinyl-1-yl]phenylpiperazines with antipsychotic and antidepressant properties. Anna Partyka, Rafał Kurczab, Vittorio Canale, Grzegorz Satała, Krzysztof Marciniec, Agnieszka Pasierb, Magdalena Jastrzębska-Więsek, Maciej Pawłowski, Anna Wesołowska, Andrzej J Bojarski, Paweł Zajdel
Bioorganic & medicinal chemistry, S0968-0896(16)30902-6 10.1016/j.bmc.2017.04.046
PMID:28529043

Thursday, 4 May 2017
The computer-aided discovery of novel family of the 5-HT6 serotonin receptor ligands among derivatives of 4-benzyl-1,3,5-triazine. Dorota Łażewska, Rafał Kurczab, Małgorzata Więcek, Katarzyna Kamińska, Grzegorz Satała, Magdalena Jastrzębska-Więsek, Anna Partyka, Andrzej J Bojarski, Anna Wesołowska, Katarzyna Kieć-Kononowicz, Jadwiga Handzlik
European journal of medicinal chemistry, S0223-5234(17)30290-8 10.1016/j.ejmech.2017.04.033
PMID:28441580

Thursday, 13 April 2017
The influence of the negative-positive ratio and screening database size on the performance of machine learning-based virtual screening. Rafał Kurczab, Andrzej J Bojarski
PloS one, 10.1371/journal.pone.0175410
PMID:28384344

Thursday, 6 April 2017
Novel 5-HT7R antagonists, arylsulfonamide derivatives of (aryloxy)propyl piperidines: Add-on effect to the antidepressant activity of SSRI and DRI, and pro-cognitive profile. Vittorio Canale, Anna Partyka, Rafał Kurczab, Martyna Krawczyk, Tomasz Kos, Grzegorz Satała, Bartłomiej Kubica, Magdalena Jastrzębska-Więsek, Anna Wesołowska, Andrzej J Bojarski, Piotr Popik, Paweł Zajdel
Bioorganic & medicinal chemistry, S0968-0896(17)30359-0 10.1016/j.bmc.2017.03.057
PMID:28391970

Wednesday, 29 March 2017
Pyrano[2,3,4-cd]indole as a Scaffold for Selective Nonbasic 5-HT6R Ligands. Jakub Staroń, Stefan Mordalski, Dawid Warszycki, Grzegorz Satała, Adam Hogendorf, Andrzej J Bojarski
ACS medicinal chemistry letters, 10.1021/acsmedchemlett.6b00482
PMID:28435524

Monday, 27 March 2017