Dr. Wojciech Kuban enters the EU Joint Programe of Neurodegenerative Disease Research JPND

Dr. Wojciech Kuban from the Department of Department of Pharmacokinetics and Drug Metabolism together with the international consortium of researchers from Klinikum rechts der Isar der TU München, Helmholz-Zentrum München, Muskelzentrum/ALS Clinic St. Gallen, Le Centre Hospitalier Régional Universitaire de Tours, Hebrew University - Hadassah Medical Center Jerusalem, Göteborgs Universitet and external collaborators from Flinders University Adelaide, Universitätsmedizin Göttingen and University of Miami were awarded funding from the JPND program for their ambitious project titled "A premotor disease signature for ALS" (premodiALS).

The aim of the project is to identify early molecular markers that occur before the motor symptoms of ALS disease, i.e permanent damage to the upper and lower motor neurons with a devastating prognosis. The research will be conducted on clinical samples from patients from different countries using advanced diagnostic technology: mass spectrometry and targeted quantitative immunoassay. The obtained results will be additionally integrated and modeled by the bioinformatics team. The identified molecular marker will also be associated with general pathological patterns of ALS. The research aims to enable early detection of the disease, improve diagnostic accuracy, but also provide information on the molecular and pathophysiological causes of ALS, enabling effective treatment in the initial stage of the disease.

Congratulations!