2nd article Open Access in Pharmacological Reports 2/2020

We strongly recommend reading an interesting article titled "Long-term vigabatrin treatment modifies pentylenetetrazole-induced seizures in mice: focused on GABA brain concentration" published in Open Access (Pharmacological Reports 2/2020):

https://rdcu.be/b3WsG

Authors: Mariusz J. Świąder, Katarzyna Świąder, Izabela Zakrocka, Maciej Krzyżanowski, Andrzej Wróbel, Jarogniew J. Łuszczka, Stanisław J. Czuczwar.

The presented results confirm anticonvulsive activity of VGB through GABA metabolism alteration and suggest care when combining VGB with ETX or CLO in the therapy.