Employees - Institute of Pharmacology - Polish Academy of Sciences

Antidepressant, anxiolytic and procognitive effects of subacute and chronic ketamine in the chronic mild stress model of depression. Mariusz Papp, Piotr Gruca, Magdalena Lason-Tyburkiewicz, Paul Willner
Behavioural pharmacology, 10.1097/FBP.0000000000000259
PMID:27759570

The Effect of Chronic Treatment with Lurasidone on Rat Liver Cytochrome P450 Expression and Activity in the Chronic Mild Stress Model of Depression. Marta Kot, Anna Haduch, Mariusz Papp, Władysława A Daniel
Drug metabolism and disposition: the biological fate of chemicals, 10.1124/dmd.117.077826
PMID:28935656

S 47445 Produces Antidepressant- and Anxiolytic-Like Effects through Neurogenesis Dependent and Independent Mechanisms. Indira Mendez-David, Jean-Philippe Guilloux, Mariusz Papp, Laurent Tritschler, Elisabeth Mocaer, Alain M Gardier, Sylvie Bretin, Denis J David
Frontiers in pharmacology, 10.3389/fphar.2017.00462
PMID:28769796

Dopaminergic mechanisms in memory consolidation and antidepressant reversal of a chronic mild stress-induced cognitive impairment`. Mariusz Papp, Piotr Gruca, Magdalena Lason-Tyburkiewicz, Ewa Litwa, Monika Niemczyk, Katarzyna Tota-Glowczyk, Paul Willner
Psychopharmacology, 10.1007/s00213-017-4651-4
PMID:28567697

Stimulatory effect of desipramine on lung metastases of adenocarcinoma MADB 106 in stress highly-sensitive and stress non-reactive rats. Beata Grygier, Marta Kubera, Danuta Wrona, Adam Roman, Agnieszka Basta-Kaim, Piotr Gruca, Mariusz Papp, Zofia Rogoz, Monika Leskiewicz, Boguslawa Budziszewska, Magdalena Regulska, Barbara Korzeniak, Katarzyna Curzytek, Katarzyna Glombik, Joanna Slusarczyk, Michael Maes, Wladyslaw Lason
Progress in neuro-psychopharmacology & biological psychiatry, S0278-5846(17)30063-5 10.1016/j.pnpbp.2017.04.024
PMID:28433460

Basal prolactin levels in rat plasma correlates with response to antidepressant treatment in animal model of depression. A Faron-Górecka, M Kuśmider, K Szafran-Pilch, M Kolasa, D Żurawek, P Gruca, M Papp, J Solich, P Pabian, M Dziedzicka-Wasylewska
Neuroscience letters, S0304-3940(17)30254-9 10.1016/j.neulet.2017.03.034
PMID:28336340

Chronic Mild Stress-Induced Alterations of Local Protein Synthesis: A Role for Cognitive Impairment. Francesca Calabrese, Paola Brivio, Piotr Gruca, Magdalena Lason-Tyburkiewicz, Mariusz Papp, Marco A Riva
ACS chemical neuroscience, 10.1021/acschemneuro.6b00392
PMID:28094500

Involvement of GABAB Receptor Signaling in Antipsychotic-like Action of the Novel Orthosteric Agonist of the mGlu4 Receptor, LSP4-2022. Monika Woźniak, Francine Acher, Marcin Marciniak, Magdalena Lasoń-Tyburkiewicz, Piotr Gruca, Mariusz Papp, Andrzej Pilc, Joanna M Wierońska
Current neuropharmacology,
PMID:26769224

Qualitative and quantitative changes in phospholipids and proteins investigated by spectroscopic techniques in animal depression model. J Depciuch, M Sowa-Kucma, G Nowak, M Papp, P Gruca, P Misztak, M Parlinska-Wojtan
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, S1386-1425(16)30722-3 10.1016/j.saa.2016.12.007
PMID:28063309

Reciprocal MicroRNA Expression in Mesocortical Circuit and Its Interplay with Serotonin Transporter Define Resilient Rats in the Chronic Mild Stress. Dariusz Zurawek, Maciej Kusmider, Agata Faron-Gorecka, Piotr Gruca, Paulina Pabian, Joanna Solich, Magdalena Kolasa, Mariusz Papp, Marta Dziedzicka-Wasylewska
Molecular neurobiology, 10.1007/s12035-016-0107-9
PMID:27660265

The Effect of Chronic Mild Stress and Imipramine on the Markers of Oxidative Stress and Antioxidant System in Rat Liver. Weronika Duda, Katarzyna Curzytek, Marta Kubera, Małgorzata Iciek, Danuta Kowalczyk-Pachel, Anna Bilska-Wilkosz, Elżbieta Lorenc-Koci, Monika Leśkiewicz, Agnieszka Basta-Kaim, Bogusława Budziszewska, Magdalena Regulska, Joanna Ślusarczyk, Piotr Gruca, Mariusz Papp, Michael Maes, Władysław Lasoń, Lucyna Antkiewicz-Michaluk
Neurotoxicity research, 10.1007/s12640-016-9614-8
PMID:26961706

Antidepressant, anxiolytic and procognitive effects of rivastigmine and donepezil in the chronic mild stress model in rats. Mariusz Papp, Piotr Gruca, Magdalena Lason-Tyburkiewicz, Paul Willner
Psychopharmacology, 10.1007/s00213-016-4206-0
PMID:26769042

Chronic mild stress-induced alterations of clock gene expression in rat prefrontal cortex: modulatory effects of prolonged lurasidone treatment. Francesca Calabrese, Elisa Savino, Mariusz Papp, Raffaella Molteni, Marco A Riva
Pharmacological research, 10.1016/j.phrs.2015.12.023 S1043-6618(15)30086-4
PMID:26742719

Chronic mild stress influences nerve growth factor through a matrix metalloproteinase-dependent mechanism. Mateusz Kucharczyk, Anna Kurek, Jan Detka, Joanna Slusarczyk, Mariusz Papp, Katarzyna Tota, Agnieszka Basta-Kaim, Marta Kubera, Wladyslaw Lason, Bogusława Budziszewska
Psychoneuroendocrinology, 10.1016/j.psyneuen.2015.12.019 S0306-4530(15)30045-7
PMID:26771945

Time-dependent miR-16 serum fluctuations together with reciprocal changes in the expression level of miR-16 in mesocortical circuit contribute to stress resilient phenotype in chronic mild stress - An animal model of depression. Dariusz Zurawek, Maciej Kusmider, Agata Faron-Gorecka, Piotr Gruca, Paulina Pabian, Magdalena Kolasa, Joanna Solich, Kinga Szafran-Pilch, Mariusz Papp, Marta Dziedzicka-Wasylewska
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, S0924-977X(15)00363-6 10.1016/j.euroneuro.2015.11.013
PMID:26628105

Stress-induced anhedonia is associated with the activation of the inflammatory system in the rat brain: Restorative effect of pharmacological intervention. Andrea C Rossetti, Mariusz Papp, Piotr Gruca, Maria Serena Paladini, Giorgio Racagni, Marco A Riva, Raffaella Molteni
Pharmacological research, 10.1016/j.phrs.2015.10.022 S1043-6618(15)00262-5
PMID:26535964

mGlu₅-GABAB interplay in animal models of positive, negative and cognitive symptoms of schizophrenia. Joanna M Wierońska, Natalia Kłeczek, Monika Woźniak, Piotr Gruca, Magdalena Łasoń-Tyburkiewicz, Mariusz Papp, Piotr Brański, Grzegorz Burnat, Andrzej Pilc
Neurochemistry international, 10.1016/j.neuint.2015.03.010 S0197-0186(15)00061-3
PMID:25863284

Effects of chronic mild stress on the development of drug dependence in rats. Mariusz Papp, Piotr Gruca, Magdalena Lason-Tyburkiewicz, Ewa Litwa, Paul Willner
Behavioural pharmacology, 10.1097/FBP.0000000000000046
PMID:24949570

Attenuation of anhedonia by cariprazine in the chronic mild stress model of depression. Mariusz Papp, Piotr Gruca, Magdalena Lasoń-Tyburkiewicz, Nika Adham, Béla Kiss, István Gyertyán
Behavioural pharmacology, 10.1097/FBP.0000000000000070
PMID:25083572

Lurasidone exerts antidepressant properties in the chronic mild stress model through the regulation of synaptic and neuroplastic mechanisms in the rat prefrontal cortex. Alessia Luoni, Flavia Macchi, Mariusz Papp, Raffaella Molteni, Marco A Riva
The international journal of neuropsychopharmacology, 10.1093/ijnp/pyu061 pyu061
PMID:25522402

Differential stress response in rats subjected to chronic mild stress is accompanied by changes in CRH-family gene expression at the pituitary level. Magdalena Kolasa, Agata Faron-Górecka, Maciej Kuśmider, Kinga Szafran-Pilch, Joanna Solich, Dariusz Żurawek, Piotr Gruca, Mariusz Papp, Marta Dziedzicka-Wasylewska
Peptides, 10.1016/j.peptides.2014.09.008 S0196-9781(14)00276-9
PMID:25236411

The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT1A receptor signaling: mechanistic studies. Joanna M Wierońska, Anna Sławińska, Magdalena Łasoń-Tyburkiewicz, Piotr Gruca, Mariusz Papp, Stevin H Zorn, Darío Doller, Natalia Kłeczek, Karolina Noworyta-Sokołowska, Krystyna Gołembiowska, Andrzej Pilc
Psychopharmacology, 10.1007/s00213-014-3657-4
PMID:25012236

1,2,3,4-Tetrahydroisoquinoline produces an antidepressant-like effect in the forced swim test and chronic mild stress model of depression in the rat: Neurochemical correlates. Edyta Możdżeń, Mariusz Papp, Piotr Gruca, Agnieszka Wąsik, Irena Romańska, Jerzy Michaluk, Lucyna Antkiewicz-Michaluk
European journal of pharmacology, 10.1016/j.ejphar.2014.01.075 S0014-2999(14)00138-1
PMID:24561050

Prolactin and its receptors in the chronic mild stress rat model of depression. A Faron-Górecka, M Kuśmider, M Kolasa, D Zurawek, P Gruca, M Papp, K Szafran, J Solich, P Pabian, I Romańska, L Antkiewicz-Michaluk, M Dziedzicka-Wasylewska
Brain research, 10.1016/j.brainres.2014.01.031 S0006-8993(14)00084-5
PMID:24508286

The antipsychotic-like effects of positive allosteric modulators of metabotropic glutamate mGlu4 receptors in rodents. Anna Sławińska, Joanna M Wierońska, Katarzyna Stachowicz, Marcin Marciniak, Magdalena Lasoń-Tyburkiewicz, Piotr Gruca, Mariusz Papp, Magdalena Kusek, Krzysztof Tokarski, Darío Doller, Andrzej Pilc
British journal of pharmacology, 10.1111/bph.12254
PMID:23714045

Antidepressant-like activity of magnesium in the chronic mild stress model in rats: alterations in the NMDA receptor subunits. Bartłomiej Pochwat, Bernadeta Szewczyk, Magdalena Sowa-Kucma, Agata Siwek, Urszula Doboszewska, Wojciech Piekoszewski, Piotr Gruca, Mariusz Papp, Gabriel Nowak
The international journal of neuropsychopharmacology, 10.1017/S1461145713001089
PMID:24067405

The reversal of cognitive, but not negative or positive symptoms of schizophrenia, by the mGlu₂/₃ receptor agonist, LY379268, is 5-HT₁A dependent. Joanna M Wierońska, A Sławińska, K Stachowicz, M Łasoń-Tyburkiewicz, P Gruca, M Papp, A Pilc
Behavioural brain research, 10.1016/j.bbr.2013.08.007 S0166-4328(13)00483-X
PMID:23948211

The antipsychotic-like effects of the mGlu group III orthosteric agonist, LSP1-2111, involves 5-HT₁A signalling. Joanna M Wierońska, Francine C Acher, Anna Sławińska, Piotr Gruca, Magdalena Lasoń-Tyburkiewicz, Mariusz Papp, Andrzej Pilc
Psychopharmacology, 10.1007/s00213-013-3005-0
PMID:23474845

Mesolimbic dopamine D₂ receptor plasticity contributes to stress resilience in rats subjected to chronic mild stress. Dariusz Zurawek, Agata Faron-Górecka, Maciej Kuśmider, Magdalena Kolasa, Piotr Gruca, Mariusz Papp, Marta Dziedzicka-Wasylewska
Psychopharmacology, 10.1007/s00213-013-2990-3
PMID:23377023

Different pattern of changes in calcium binding proteins immunoreactivity in the medial prefrontal cortex of rats exposed to stress models of depression. Monika Zadrożna, Barbara Nowak, Magdalena Łasoń-Tyburkiewicz, Małgorzata Wolak, Magdalena Sowa-Kućma, Mariusz Papp, Grażyna Ossowska, Andrzej Pilc, Gabriel Nowak
Pharmacological reports : PR,
PMID:22358102

The 5-HT3 receptor antagonists ICS 205-930 and GR38032F, putative anxiolytic drugs, differ from diazepam in their pharmacological profile. M Papp, E Przegalinski
Journal of psychopharmacology (Oxford, England), 10.1177/026988118900300103
PMID:22156306

Models of affective illness: chronic mild stress in the rat. Mariusz Papp
Current protocols in pharmacology, 10.1002/0471141755.ph0509s57
PMID:22684722

Long-lasting increase in [³H]CP55,940 binding to CB1 receptors following cocaine self-administration and its withdrawal in rats. Przemysław Adamczyk, Agata Faron-Górecka, Maciej Kuśmider, Marta Dziedzicka-Wasylewska, Mariusz Papp, Małgorzata Filip
Brain research, 10.1016/j.brainres.2012.02.052
PMID:22425184

The effects of cannabinoid CB1, CB2 and vanilloid TRPV1 receptor antagonists on cocaine addictive behavior in rats. Przemysław Adamczyk, Joanna Miszkiel, Andrew C McCreary, Małgorzata Filip, Mariusz Papp, Edmund Przegaliński
Brain research, 10.1016/j.brainres.2012.01.030
PMID:22325096

Effects of serotonin (5-HT)6 receptor ligands on responding for cocaine reward and seeking in rats. Katarzyna Fijał, Agnieszka Pachuta, Andrew C McCreary, Karolina Wydra, Ewa Nowak, Mariusz Papp, Przemysław Bieńkowski, Jolanta Kotlińska, Małgorzata Filip
Pharmacological reports : PR,
PMID:21273657

Effects of melatonin in a place preference conditioning depend on the time of administration. Mariusz Papp, Ewa Litwa, Magdalena Łasoń-Tyburkiewicz, Piotr Gruca
Pharmacological reports : PR,
PMID:21273659

Alterations in hippocampal calcium-binding neurons induced by stress models of depression: a preliminary assessment. Barbara Nowak, Monika Zadrożna, Grażyna Ossowska, Magdalena Sowa-Kućma, Piotr Gruca, Mariusz Papp, Małgorzata Dybała, Andrzej Pilc, Gabriel Nowak
Pharmacological reports : PR,
PMID:21273679

Effect of chronic mild stress and imipramine on the proteome of the rat dentate gyrus. Sylwia Kedracka-Krok, Ewelina Fic, Urszula Jankowska, Marcin Jaciuk, Piotr Gruca, Mariusz Papp, Maciej Kusmider, Joanna Solich, Janusz Debski, Michal Dadlez, Marta Dziedzicka-Wasylewska
Journal of neurochemistry, 10.1111/j.1471-4159.2010.06652.x
PMID:20180829

Effects of imipramine or GABA(B) receptor ligands on the immobility, swimming and climbing in the forced swim test in rats following discontinuation of cocaine self-administration. Małgorzata Frankowska, Anna Gołda, Karolina Wydra, Piotr Gruca, Mariusz Papp, Małgorzata Filip
European journal of pharmacology, 10.1016/j.ejphar.2009.10.049
PMID:19878670

Antidepressant-like activity of zinc: further behavioral and molecular evidence. Magdalena Sowa-Kućma, Beata Legutko, Bernadeta Szewczyk, Kinga Novak, Paweł Znojek, Ewa Poleszak, Mariusz Papp, Andrzej Pilc, Gabriel Nowak
Journal of neural transmission (Vienna, Austria : 1996), 10.1007/s00702-008-0115-7
PMID:18766297

Effect of imipramine treatment on plasma dopamine beta-hydroxylase activity in chronic mild stress in rats. Mariola Grabowska, Małgorzata Schlegel-Zawadzka, Mariusz Papp, Gabriel Nowak
Polish journal of pharmacology,
PMID:15662096

Anxiolytic-like activity of agomelatine and melatonin in three animal models of anxiety. Mariusz Papp, Ewa Litwa, Piotr Gruca, Elisabeth Mocaër
Behavioural pharmacology,
PMID:16377959

Antidepressant-like activity of CGP 36742 and CGP 51176, selective GABAB receptor antagonists, in rodents. G Nowak, A Partyka, A Pałucha, B Szewczyk, J M Wierońska, M Dybała, M Metz, T Librowski, W Froestl, M Papp, A Pilc
British journal of pharmacology,
PMID:16921399

Zinc treatment induces cortical brain-derived neurotrophic factor gene expression. Gabriel Nowak, Beata Legutko, Bernadeta Szewczyk, Mariusz Papp, Marek Sanak, Andrzej Pilc
European journal of pharmacology,
PMID:15145706

Behavioural and biochemical studies of citalopram and WAY 100635 in rat chronic mild stress model. Mariusz Papp, Irena Nalepa, Lucyna Antkiewicz-Michaluk, Connie Sánchez
Pharmacology, biochemistry, and behavior,
PMID:11900821

Selective blockade of drug-induced place preference conditioning by ACPC, a functional NDMA-receptor antagonist. Marius Papp, Piotr Gruca, Paul Willner
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
PMID:12431848

Effect of agomelatine in the chronic mild stress model of depression in the rat. Mariusz Papp, Piotr Gruca, Pierre-Alain Boyer, Elisabeth Mocaër
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
PMID:12655314

The NK1-receptor antagonist NKP608 has an antidepressant-like effect in the chronic mild stress model of depression in rats. M Papp, A Vassout, C Gentsch
Behavioural brain research,
PMID:10996404

Changes in dopamine receptor mRNA expression following chronic mild stress and chronic antidepressant treatment. M Dziedzicka-Wasylewska, P Willner, M Papp
Behavioural pharmacology,
PMID:9832973

Effect of chronic mild stress and prolonged treatment with imipramine on the levels of endogenous Met-enkephalin in the rat dopaminergic mesolimbic system. M Dziedzicka-Wasylewska, M Papp
Polish journal of pharmacology,
PMID:9112628

Effect of chronic treatment with imipramine on interleukin 1 and interleukin 2 production by splenocytes obtained from rats subjected to a chronic mild stress model of depression. M Kubera, A Symbirtsev, A Basta-Kaim, J Borycz, A Roman, M Papp, M Claesson
Polish journal of pharmacology,
PMID:9112692

Antidepressant-like effects of 1-aminocyclopropanecarboxylic acid and D-cycloserine in an animal model of depression. M Papp, E Moryl
European journal of pharmacology,
PMID:8982680

Pharmacological validation of the chronic mild stress model of depression. M Papp, E Moryl, P Willner
European journal of pharmacology,
PMID:8838448

Differential effects of agents acting at various sites of the NMDA receptor complex in a place preference conditioning model. M Papp, E Moryl, M L Maccecchini
European journal of pharmacology,
PMID:8997600

Discriminative stimulus effects of the NMDA receptor antagonists MK-801 and CGP 37849 in rats. W Zajaczkowski, E Moryl, M Papp
Pharmacology, biochemistry, and behavior,
PMID:8870053

Effect of chronic mild stress on circadian rhythms in the locomotor activity in rats. Z Gorka, E Moryl, M Papp
Pharmacology, biochemistry, and behavior,
PMID:8728562

The effect of 5-HT1A receptor ligands in a chronic mild stress model of depression. E Przegaliński, E Moryl, M Papp
Neuropharmacology,
PMID:8570028

The effect of chronic treatment with imipramine on the immunoreactivity of animals subjected to a chronic mild stress model of depression. M Kubera, A Basta-Kaim, M Papp
Immunopharmacology,
PMID:8557522

Different effects of short- and long-term treatment with imipramine on the apomorphine- and food-induced place preference conditioning in rats. M Papp
Pharmacology, biochemistry, and behavior,
PMID:3227037

Differential effects of short-and long-term antidepressant treatments on the food-induced place preference conditioning in rats. M. Papp
Behavioural pharmacology,
PMID:11175388

Professor Mariusz Papp, PhD

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