Department of Brain Biochemistry
-
Vitamin D3 and Ischemic Stroke: A Narrative Review.
Władysław Lasoń, Danuta Jantas, Monika Leśkiewicz, Magdalena Regulska, Agnieszka Basta-Kaim
Antioxidants (Basel, Switzerland), 2120 10.3390/antiox11112120
PMID:36358492 -
The Impact of the Combined Administration of 1MeTIQ and MK-801 on Cell Viability, Oxidative Stress Markers, and Glutamate Release in the Rat Hippocampus.
Agnieszka Wąsik, Magdalena Białoń, Danuta Jantas, Marcelina Żarnowska
Neurotoxicity research, 10.1007/s12640-021-00428-9
PMID:34665405 -
undefined
Danuta Jantas, Janusz Malarz, Thanh Nguyen Le, Anna Stojakowska
International journal of molecular sciences, 10363 10.3390/ijms221910363
PMID:34638702 -
Preclinical Evidence for the Interplay between Oxidative Stress and RIP1-Dependent Cell Death in Neurodegeneration: State of the Art and Possible Therapeutic Implications.
Danuta Jantas, Władysław Lasoń
Antioxidants (Basel, Switzerland), 1518 10.3390/antiox10101518
PMID:34679652 -
Neuroprotective Effects of Methyl Caffeate against Hydrogen Peroxide-Induced Cell Damage: Involvement of Caspase 3 and Cathepsin D Inhibition.
Danuta Jantas, Jakub Chwastek, Janusz Malarz, Anna Stojakowska, Władysław Lasoń
Biomolecules, E1530 10.3390/biom10111530
PMID:33182454 -
Back and to the Future: From Neurotoxin-Induced to Human Parkinson's Disease Models.
Mikko Airavaara, Ilmari Parkkinen, Julia Konovalova, Katrina Albert, Piotr Chmielarz, Andrii Domanskyi
Current protocols in neuroscience, 10.1002/cpns.88
PMID:32049438 -
MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System.
Emmi Pakarinen, Tatiana Danilova, Vootele Võikar, Piotr Chmielarz, Petteri Piepponen, Mikko Airavaara, Mart Saarma, Maria Lindahl
eNeuro, ENEURO.0477-19.2019 10.1523/ENEURO.0477-19.2019
PMID:32005751 -
Neuroprotective Effects of Necrostatin-1 Against Oxidative Stress-Induced Cell Damage: an Involvement of Cathepsin D Inhibition.
Danuta Jantas, Jakub Chwastek, Beata Grygier, Władysław Lasoń
Neurotoxicity research, 10.1007/s12640-020-00164-6
PMID:31960265 -
Interplay between MicroRNAs and Oxidative Stress in Neurodegenerative Diseases.
Julia Konovalova, Dmytro Gerasymchuk, Ilmari Parkkinen, Piotr Chmielarz, Andrii Domanskyi
International journal of molecular sciences, E6055 10.3390/ijms20236055
PMID:31801298 -
Functionally Distinctive Ptch Receptors Establish Multimodal Hedgehog Signaling in the Tooth Epithelial Stem Cell Niche.
Martin Binder, Piotr Chmielarz, Peter J Mckinnon, Leah C Biggs, Irma Thesleff, Anamaria Balic
Stem cells (Dayton, Ohio), 10.1002/stem.3042
PMID:31145830 -
Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism.
Grzegorz Kreiner, Katarzyna Rafa-Zabłocka, Justyna Barut, Piotr Chmielarz, Marta Kot, Monika Bagińska, Rosanna Parlato, Władysława Anna Daniel, Irena Nalepa
Scientific reports, 10.1038/s41598-019-41756-3
PMID:30918302 -
Selective Depletion of CREB in Serotonergic Neurons Affects the Upregulation of Brain-Derived Neurotrophic Factor Evoked by Chronic Fluoxetine Treatment.
Katarzyna Rafa-Zabłocka, Grzegorz Kreiner, Monika Bagińska, Irena Nalepa
Frontiers in neuroscience, 10.3389/fnins.2018.00637
PMID:30294251 -
What have we learned recently from transgenic mouse models about neurodegeneration? The most promising discoveries of this millennium.
Grzegorz Kreiner
Pharmacological reports : PR, S1734-1140(17)30841-1 10.1016/j.pharep.2018.09.006
PMID:30312896 -
New evidences for a role of mGluR7 in astrocyte survival: Possible implications for neuroprotection.
Danuta Jantas, Tomasz Lech, Sławomir Gołda, Andrzej Pilc, Władysław Lasoń
Neuropharmacology, S0028-3908(18)30585-9 10.1016/j.neuropharm.2018.08.035
PMID:30170084 -
The Protective Effect of Repeated 1MeTIQ Administration on the Lactacystin-Induced Impairment of Dopamine Release and Decline in TH Level in the Rat Brain.
Agnieszka Wąsik, Irena Romańska, Agnieszka Zelek-Molik, Irena Nalepa, Lucyna Antkiewicz-Michaluk
Neurotoxicity research, 10.1007/s12640-018-9939-6
PMID:30129004
-
Aneta Fraczek-Szczypta, Danuta Jantas, Filip Ciepiela, Justyna Grzonka. Graphene oxide-conductive polymer nanocomposite coatings obtained by the EPD method as substrates for neurite outgrowth. Diamond & Related Materials 102 (2020) 107663.
-
Marek Piotrowski, Danuta Jantas, Monika Leśkiewicz, Krzysztof Szczepanowicz, Piotr Warszyński, Władysław Lasoń. Polyelectrolyte-coated nanocapsules containing cyclosporine A protect neuronal-like cells against oxidative stress-induced cell damage. Colloids and Surfaces A: Physicochemical and Engineering Aspects Volume 555, 20 October 2018, Pages 264-269.
-
Aneta Fraczek-Szczypta, Danuta Jantas, Filip Ciepiela, Justyna Grzonka, Andrzej Bernasike, Mateusz Marzec. Carbon nanomaterials coatings – Properties and influence on nerve cells response. Diamond and Related Materials Volume 84, April 2018, Pages 127–140.
- M. Szczęch, K. Szczepanowicz, D. Jantas, M. Piotrowski, A. Kida, W. Lasoń, P. Warszyński. Neuroprotective action of undecylenic acid (UDA) encapsulated into PCL nanocarriers. Colloids and Surfaces A 532 (2017) 41–47.
-
Marek Piotrowski, Krzysztof Szczepanowicz, Danuta Jantas, Monika Leskiewicz, Władysław Lason, Piotr Warszynski. Emulsion-core and polyelectrolyte-shell nanocapsules: biocompatibility and neuroprotection against SH-SY5Y cells. J Nanopart Res (2013) 15:1-12.
-
Gręda A., Jantas D. Dysfunkcje mitochondriów w chorobach neurodegeneracyjnych: potencjalny punkt uchwytu dla leków neuroprotekcyjnych. Postępy Biologii Komórki, TOM 39 2012 NR 3 (321–344). Review in Polish.
-
Danuta Jantas. Thyreoliberin (TRH) – the regulatory neuropeptide of CNS homeostasis. Advances in Cell Biology 2010, 2:138-152.
- Jantas D. Cell-Based Systems of Depression: An Overview. In: Herbal Medicine in Depression. Ed. Clara Grosso. Springer, Switzerland 2016, p. 75-117. DOI 10.1007/978-3-319-14021-6.
- Lasoń W., Jantas D. Rola epigenetyki w mechanizmach i leczeniu padaczki (The role of epigenetics in pathomechanisms and epilepsy treatment). Article In Polish. Epileptologia 2009, 17:113-122.
- Jantas-Skotniczna D. Estrogeny – nie tylko hormony płciowe (Rola estrogenów w Ośrodkowym Układzie Nerwowym). [Estrogens – not only sexual hormons (The role of estrogens In Central Nervous System)]. Wszechświat, 2004; 105: 191-194. Review. Polish.
- Jantas-Skotniczna D. ALS – cichy zabójca (Nasze szanse w walce ze stwardnieniem bocznym zanikowym). [ALS – the sileni killer (Our chances to combat Amyotropic Lateral Sclerosis)]. Wszechświat, 2006; 107: 31-33. Review. Polish.
-
The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopamine receptor ligands, Danuta Jantas, PhD
Consortium partner in project SONATA 17 UMO-2021/43/D/NZ7/00891 -
Project PASIFIC Call 1 TheraLanOx "Neuroprotective properties of theranostic lanthanide oxide nanoparticles against neurotoxin-induced cellular models of Parkinson’s disease", Danuta Jantas, PhD
Project PI: Dr Rugmani Meenambal; project supervisors: Dr hab. Danuta Jantas and Prof. dr hab. Piotr Warszyński
-
Hybrid carbon composites for stimulation of cells of the central nervous system, Danuta Jantas, PhD
Consortium partner in project OPUS 20 2020/39/B/ST5/02126 -
Evaluation of the influence of progressive noradrenergic neurodegeneration on dopaminergic system functioning in context of presymptomatic phase of Parkinson's disease., Grzegorz Kreiner, PhD
OPUS13 2017/25/B/NZ7/02406
Principal Investigator: Dr Grzegorz Kreiner -
, Professor Irena Nalepa, PhD
-
, Professor Irena Nalepa, PhD
-
Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment, Grzegorz Kreiner, PhD
OPUS7 2014/13/B/NZ7/02293
Principal Investigator: Dr Grzegorz Kreiner -
The study on the role of metabotropic glutamate receptor subtype 8 (mGluR8) in cancer cells - potential target for new anticancer drugs, Danuta Jantas, PhD
Grant NCN OPUS 3 2012/05/B/NZ3/00452.
-
Pharmacological evaluation of possible neuroprotective strategies in novel genetic mouse models of progressive neurodegeneration, based on tissue specific inducible Cre/loxP system , Grzegorz Kreiner, PhD
OPUS2 2011/03/B/NZ7/05949
Principal Investigator: Dr Grzegorz Kreiner
-
The study on the neuroprotective potential of metabotropic glutamate group II and III receptors in in vitro and in vivo apoptosis models, Danuta Jantas, PhD
Grant KBN nr N N405 611638. -
, Professor Irena Nalepa, PhD
-
Investigation of noradrenergic and glucocorticoid system interactions in GRDBHCre mice and their evaluation as a potential model of depression, Grzegorz Kreiner, PhD
POIG 01.01.02-12-004/09 DeMeTer (Depression – Mechanisms – Therapy).
Task 1.1 Subtask 1.1.2. Main topic: Modelling of depression – strategy of learning about its aetiology. Principal Investigator of task 1.2: Dr Grzegorz Kreiner
-
, Professor Irena Nalepa, PhD
-
2020 - Bronze Cross of Merit from President of Poland; for significant contribution to science development in Poland, Danuta Jantas, PhD
Tuesday, 29 June 2021 -
2017 - Publons Peer Review Award, Multidisciplinary, Danuta Jantas, PhD
Friday, 1 September 2017 -
2009 - Young Investigator Award, Neuropeptides Festival, Salzburg, Austria. , Danuta Jantas, PhD
Thursday, 23 July 2009
interests
techniques
- analysis and interpretation of big genomic data-sets
- cDNA microarrays
- chronic psychosocial stress
- conditioned place aversion
- conditioned place preference
- fear conditioning
- genotyping
- immune cells tissue cultures
- in vitro transfection
- protein microarrays
- spectroscopy UV-VIS
- tail flick test
- TLDA microarrays
keywords
- Alzheimer disease
- animal models
- antidepressants
- apoptosis
- bioinformatics
- depression
- drug addiction
- G-protein coupled receptors
- gene expression
- glia
- Glioblastoma
- glutamate
- glutamatergic receptors
- hippocampus
- imipramine
- metabotropic glutamate receptors
- mitochondrial proteins
- molecular biology
- mouse
- neurodegeneration
- neurons
- neuroprotection
- neurotoxicity
- neurotrophic factors
- NMDA receptor
- noradrenaline
- Parkinson's disease
- prefrontal cortex
- psychopharmacology
- rat
- second messengers
- signaling proteins
- stress
- synapse
- thalamus
- treatment-resistant depression