Professor Marzena Maćkowiak, PhD
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Effect of Psilocybin and Ketamine on Brain Neurotransmitters, Glutamate Receptors, DNA and Rat Behavior.
Adam Wojtas, Agnieszka Bysiek, Agnieszka Wawrzczak-Bargiela, Zuzanna Szych, Iwona Majcher-Maślanka, Monika Herian, Marzena Maćkowiak, Krystyna Gołembiowska
International journal of molecular sciences, 6713 10.3390/ijms23126713
PMID:35743159
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Neurotoxicological profile of the hallucinogenic compound 25I-NBOMe.
Monika Herian, Adam Wojtas, Marzena Maćkowiak, Agnieszka Wawrzczak-Bargiela, Anna Solarz, Agnieszka Bysiek, Katarzyna Madej, Krystyna Gołembiowska
Scientific reports, 10.1038/s41598-022-07069-8
PMID:35190675
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Prenatal Exposure to Triclocarban Impairs ESR1 Signaling and Disrupts Epigenetic Status in Sex-Specific Ways as Well as Dysregulates the Expression of Neurogenesis- and Neurotransmitter-Related Genes in the Postnatal Mouse Brain.
Agnieszka Wnuk, Joanna Rzemieniec, Karolina Przepiórska, Bernadeta Angelika Pietrzak, Marzena Maćkowiak, Małgorzata Kajta
International journal of molecular sciences, 13121 10.3390/ijms222313121
PMID:34884933
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Magdalena Kusek, Marcin Siwiec, Joanna Ewa Sowa, Bartosz Bobula, Wiktor Bilecki, Izabela Ciurej, Maria Kaczmarczyk, Tomasz Kowalczyk, Marzena Maćkowiak, Grzegorz Hess, Krzysztof Tokarski
Neuropharmacology, S0028-3908(21)00334-8 10.1016/j.neuropharm.2021.108779
PMID:34481835
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Inhibition of BET Proteins during Adolescence Affects Prefrontal Cortical Development: Relevance to Schizophrenia.
Wiktor Bilecki, Agnieszka Wawrzczak-Bargieła, Iwona Majcher-Maślanka, Magdalena Chmelova, Marzena Maćkowiak
International journal of molecular sciences, 8710 10.3390/ijms22168710
PMID:34445411
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Prenatal MAM treatment altered fear conditioning following social isolation: Relevance to schizophrenia.
Wiktor Bilecki, Joachim Latusz, Kinga Gawlińska, Magdalena Chmelova, Marzena Maćkowiak
Behavioural brain research, S0166-4328(21)00119-4 10.1016/j.bbr.2021.113231
PMID:33737089
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Chronic Lorcaserin Treatment Reverses the Nicotine Withdrawal-Induced Disruptions to Behavior and Maturation in Developing Neurons in the Hippocampus of Rats.
Magdalena Zaniewska, Agnieszka Nikiforuk, Urszula Głowacka, Sabina Brygider, Julita Wesołowska, Ewa Litwa, Marzena Maćkowiak
International journal of molecular sciences, E868 10.3390/ijms22020868
PMID:33467149
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Knockdown of the astrocytic glucocorticoid receptor in the central nucleus of the amygdala diminishes conditioned fear expression and anxiety.
Lucja Wiktorowska, Wiktor Bilecki, Magdalena Tertil, Lucja Kudla, Lukasz Szumiec, Marzena Mackowiak, Ryszard Przewlocki
Behavioural brain research, S0166-4328(20)30794-4 10.1016/j.bbr.2020.113095
PMID:33359366
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Early-life blockade of NMDA receptors induces epigenetic abnormalities in the adult medial prefrontal cortex: possible involvement in memory impairment in trace fear conditioning.
Joachim Latusz, Marzena Maćkowiak
Psychopharmacology, 10.1007/s00213-019-05362-5
PMID:31654083
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Adolescent social isolation affects parvalbumin expression in the medial prefrontal cortex in the MAM-E17 model of schizophrenia.
Marzena Maćkowiak, Joachim Latusz, Urszula Głowacka, Ewelina Bator, Wiktor Bilecki
Metabolic brain disease, 10.1007/s11011-018-0359-3
PMID:30519836
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Triclocarban Disrupts the Epigenetic Status of Neuronal Cells and Induces AHR/CAR-Mediated Apoptosis.
M Kajta, A Wnuk, J Rzemieniec, W Lason, M Mackowiak, E Chwastek, M Staniszewska, I Nehring, A K Wojtowicz
Molecular neurobiology, 10.1007/s12035-018-1285-4
PMID:30097849
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Adolescent Social Isolation Affects Schizophrenia-Like Behavior in the MAM-E17 Model of Schizophrenia.
Ewelina Bator, Joachim Latusz, Urszula Głowacka, Aleksandra Radaszkiewicz, Kinga Mudlaff, Marzena Maćkowiak
Neurotoxicity research, 10.1007/s12640-018-9888-0
PMID:29536265
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Adolescent environmental enrichment prevents the emergence of schizophrenia-like abnormalities in a neurodevelopmental model of schizophrenia.
Ewelina Bator, Joachim Latusz, Krzysztof Wędzony, Marzena Maćkowiak
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, S0924-977X(17)32004-7 10.1016/j.euroneuro.2017.11.013
PMID:29174863
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Fear memory in a neurodevelopmental model of schizophrenia based on the postnatal blockade of NMDA receptors.
Joachim Latusz, Aleksandra Radaszkiewicz, Ewelina Bator, Krzysztof Wędzony, Marzena Maćkowiak
Pharmacological reports : PR, S1734-1140(16)30288-2 10.1016/j.pharep.2016.10.012
PMID:27907838
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Early-life stress increases the survival of midbrain neurons during postnatal development and enhances reward-related and anxiolytic-like behaviors in a sex-dependent fashion.
Agnieszka Chocyk, Iwona Majcher-Maślanka, Aleksandra Przyborowska, Marzena Maćkowiak, Krzysztof Wędzony
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, S0736-5748(15)00409-8 10.1016/j.ijdevneu.2015.05.002
PMID:25980793
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Valproic acid (VPA) reduces sensorimotor gating deficits and HDAC2 overexpression in the MAM animal model of schizophrenia.
Ewelina Bator, Joachim Latusz, Aleksandra Radaszkiewicz, Krzysztof Wędzony, Marzena Maćkowiak
Pharmacological reports : PR, 10.1016/j.pharep.2015.04.004 S1734-1140(15)00073-0
PMID:26481530
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Potential roles of NCAM/PSA-NCAM proteins in depression and the mechanism of action of antidepressant drugs.
Krzysztof Wędzony, Agnieszka Chocyk, Marzena Maćkowiak
Pharmacological reports : PR,
PMID:24552994
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MK-801, a NMDA receptor antagonist, increases phosphorylation of histone H3 in the rat medial prefrontal cortex.
Marzena Maćkowiak, Rafał Guzik, Dorota Dudys, Ewelina Bator, Krzysztof Wędzony
Pharmacological reports : PR,
PMID:24399707
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Neuroligins, synapse balance and neuropsychiatric disorders.
Marzena Maćkowiak, Patrycja Mordalska, Krzysztof Wędzony
Pharmacological reports : PR, 10.1016/j.pharep.2014.04.011 S1734-1140(14)00167-4
PMID:25149987
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Prenatal MAM administration affects histone H3 methylation in postnatal life in the rat medial prefrontal cortex.
Marzena Maćkowiak, Ewelina Bator, Joachim Latusz, Patrycja Mordalska, Krzysztof Wędzony
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 10.1016/j.euroneuro.2013.05.013 S0924-977X(13)00175-2
PMID:23932495
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Impact of maternal separation on neural cell adhesion molecules expression in dopaminergic brain regions of juvenile, adolescent and adult rats.
Agnieszka Chocyk, Dorota Dudys, Aleksandra Przyborowska, Marzena Maćkowiak, Krzysztof Wędzony
Pharmacological reports : PR,
PMID:21273681
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Cocaine enhances ST8SiaII mRNA expression and neural cell adhesion molecule polysialylation in the rat medial prefrontal cortex.
M Maćkowiak, P Mordalska, D Dudys, M Korostyński, E Bator, K Wedzony
Neuroscience, 10.1016/j.neuroscience.2011.04.030
PMID:21536109
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The impact of maternal separation on the number of tyrosine hydroxylase-expressing midbrain neurons during different stages of ontogenesis.
A Chocyk, A Przyborowska, D Dudys, I Majcher, M Maćkowiak, K Wędzony
Neuroscience, 10.1016/j.neuroscience.2011.03.008
PMID:21396433
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Maternal separation affects the number, proliferation and apoptosis of glia cells in the substantia nigra and ventral tegmental area of juvenile rats.
A Chocyk, D Dudys, A Przyborowska, I Majcher, M Maćkowiak, K Wędzony
Neuroscience, 10.1016/j.neuroscience.2010.11.037
PMID:21108994
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Hetero-dimerization of serotonin 5-HT(2A) and dopamine D(2) receptors.
Sylwia Lukasiewicz, Agnieszka Polit, Sylwia Kędracka-Krok, Krzysztof Wędzony, Marzena Maćkowiak, Marta Dziedzicka-Wasylewska
Biochimica et biophysica acta, 10.1016/j.bbamcr.2010.08.010
PMID:20831885
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ERK signalling pathway is not involved in PSA-NCAM-dependent alterations of hippocampal plasticity evoked by CB1 receptor activation.
Marzena Maćkowiak, Dorota Dudys, Krzysztof Wedzony
Pharmacological reports : PR,
PMID:20081235
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Impact of postnatal dexamethasone on psychotomimetic effects of MK-801 measured on adult rats.
Krzysztof Wedzony, Katarzyna Markowicz-Kula, Agnieszka Chocyk, Katarzyna Fijał, Aleksandra Przyborowska, Marzena Maćkowiak
Pharmacological reports : PR,
PMID:20081238
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5-HT1A receptors mediate detrimental effects of cocaine on long-term potentiation and expression of polysialylated neural cell adhesion molecule protein in rat dentate gyrus.
M Grzegorzewska, M Maćkowiak, K Wedzony, G Hess
Neuroscience, 10.1016/j.neuroscience.2009.12.015
PMID:20006974
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Detrimental effect of postnatal blockade of N-methyl-D-aspartate receptors on sensorimotor gating is reversed by neuroleptic drugs.
Krzysztof Wedzony, Katarzyna Fijał, Marzena Maćkowiak, Agnieszka Chocyk
Pharmacological reports : PR,
PMID:19211977
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Activation of CB1 cannabinoid receptors impairs memory consolidation and hippocampal polysialylated neural cell adhesion molecule expression in contextual fear conditioning.
M Maćkowiak, A Chocyk, D Dudys, K Wedzony
Neuroscience, 10.1016/j.neuroscience.2008.11.037
PMID:19110037
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Repeated risperidone treatment increases the expression of NCAM and PSA-NCAM protein in the rat medial prefrontal cortex.
Marzena Maćkowiak, Dorota Dudys, Agnieszka Chocyk, Krzysztof Wedzony
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 10.1016/j.euroneuro.2008.10.001
PMID:19042107
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A search for colocalization of serotonin 5-HT2A and 5-HT1A receptors in the rat medial prefrontal and entorhinal cortices--immunohistochemical studies.
K Wedzony, A Chocyk, M Maćkowiak
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society,
PMID:18622042
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Aryl hydrocarbon receptor-mediated apoptosis of neuronal cells: a possible interaction with estrogen receptor signaling.
M Kajta, A K Wójtowicz, M Maćkowiak, W Lasoń
Neuroscience, 10.1016/j.neuroscience.2008.10.045
PMID:19027052
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Cocaine decreases the expression of PSA-NCAM protein and attenuates long-term potentiation via glucocorticoid receptors in the rat dentate gyrus.
Marzena Maćkowiak, Małgorzata Grzegorzewska, Bogusława Budziszewska, Agnieszka Chocyk, Grzegorz Hess, Krzysztof Wedzony
The European journal of neuroscience, 10.1111/j.1460-9568.2008.06255.x
PMID:18588533
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Glutamatergic neurons of rat medial prefrontal cortex innervating the ventral tegmental area are positive for serotonin 5-HT1A receptor protein.
K Wedzony, A Chocyk, W Kolasiewicz, M Maćkowiak
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society,
PMID:18195476
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Impact of postnatal blockade of N-methyl-D-aspartate receptors on rat behavior: a search for a new developmental model of schizophrenia.
K Wedzony, K Fijal, M Mackowiak, A Chocyk, W Zajaczkowski
Neuroscience, 10.1016/j.neuroscience.2008.03.016
PMID:18434025
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Acute activation of CB1 cannabinoid receptors transiently decreases PSA-NCAM expression in the dentate gyrus of the rat hippocampus.
Marzena Maćkowiak, Agnieszka Chocyk, Katarzyna Markowicz-Kula, Krzysztof Wedzony
Brain research,
PMID:17355876
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Neurogenesis in the adult brain.
Marzena Maćkowiak, Agnieszka Chocyk, Katarzyna Markowicz-Kula, Krzysztof Wedzony
Polish journal of pharmacology,
PMID:15662080
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Purvalanol A, inhibitor of cyclin-dependent kinases attenuates proliferation of cells in the dentate gyrus of the adult rat hippocampus.
Marzena Maćkowiak, Wacław Kolasiewicz, Katarzyna Markowicz-Kula, Krzysztof Wedzony
Pharmacological reports : PR,
PMID:16382206
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Acute and repeated administration of cocaine differentially regulates expression of PSA-NCAM-positive neurons in the rat hippocampus.
Marzena Maćkowiak, Katarzyna Markowicz-Kula, Katarzyna Fijał, Krzysztof Wedzony
Brain research,
PMID:16081054
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The effect of 'binge' cocaine administration on the expression of cyclin-dependent kinase 5 and its activator p35 in various regions of rat brain.
Krzysztof Wedzony, Katarzyna Markowicz-Kula, Agnieszka Chocyk, Katarzyna Fijał, Marzena Maćkowiak
Brain research,
PMID:16263094
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Alterations in the dendritic morphology of prefrontal pyramidal neurons in adult rats after blockade of NMDA receptors in the postnatal period.
Krzysztof Wedzony, Katarzyna Fijał, Marzena Maćkowiak
Brain research,
PMID:16257395
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Role of glucocorticoids in the regulation of dopaminergic neurotransmission.
Anna Czyrak, Marzena Maćkowiak, Agnieszka Chocyk, Katarzyna Fijał, Krzystof Wedzony
Polish journal of pharmacology,
PMID:14704461
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Serotonin 5-HT1A receptors might control the output of cortical glutamatergic neurons in rat cingulate cortex.
Anna Czyrak, Klaudia Czepiel, Marzena Maćkowiak, Agnieszka Chocyk, Krzysztof Wedzony
Brain research,
PMID:14519510
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Different pattern of brain c-Fos expression following re-exposure to ethanol or sucrose self-administration environment.
Krzysztof Wedzony, Eliza Koros, Anna Czyrak, Agnieszka Chocyk, Klaudia Czepiel, Katarzyna Fijal, Marzena Mackowiak, Artur Rogowski, Wojciech Kostowski, Przemyslaw Bienkowski
Naunyn-Schmiedeberg's archives of pharmacology,
PMID:14574439
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8-OHDPAT-induced disruption of prepulse inhibition in rats is attenuated by prolonged corticosterone treatment.
Anna Czyrak, Marzena Maćkowiak, Agnieszka Chocyk, Katarzyna Fijał, Anna Gadek-Michalska, Krzysztof Wedzony
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
PMID:12700680
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DOI, an agonist of 5-HT2A/2C serotonin receptor, alters the expression of cyclooxygenase-2 in the rat parietal cortex.
M Mackowiak, A Chocyk, M Sanak, A Czyrak, K Fijał, K Wedzony
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society,
PMID:12369737
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An AMPA receptor potentiator modulates hippocampal expression of BDNF: an in vivo study.
Marzena Mackowiak, Michael J O'Neill, Caroline A Hicks, David Bleakman, Phil Skolnick
Neuropharmacology,
PMID:12213254
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Inhibition of arachidonic acid cascade attenuates the induction of c-Fos proteins by DOI, 5-HT2A/2C receptor agonist, in the rat cortex.
Marzena Maćkowiak, Anna Czyrak, Krzysztof Wedzony
Polish journal of pharmacology,
PMID:12020047
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Kainate receptor agonists, antagonists and allosteric modulators.
D Bleakman, M R Gates, A M Ogden, M Mackowiak
Current pharmaceutical design,
PMID:11945137
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Prolonged corticosterone treatment alters the responsiveness of 5-HT1A receptors to 8-OH-DPAT in rat CA1 hippocampal neurons.
Anna Czyrak, Marzena Maćkowiak, Agnieszka Chocyk, Katarzyna Fijał, Krzysztof Tokarski, Maria Bijak, Krzysztof Wedzony
Naunyn-Schmiedeberg's archives of pharmacology,
PMID:12237750
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Distribution of dopamine D1 receptors in the nucleus paraventricularis of the hypothalamus in rats: an immunohistochemical study.
A Czyrak, A Chocyk, M Maćkowiak, K Fijał, K Wedzony
Brain research. Molecular brain research,
PMID:11146123
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[The involvement of 5-HT1a serotonin receptors in the pathophysiology and pharmacotherapy of schizophrenia].
M Maćkowiak, A Czyrak, K Wedzony
Psychiatria polska,
PMID:11059260
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Metyrapone, an inhibitor of corticosterone synthesis, blocks the kainic acid-induced expression of HSP 70.
A Czyrak, K Fijał, M Maćkowiak, W Zajaczkowski, K Wedzony
Synapse (New York, N.Y.),
PMID:11018788
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WAY 100135, an antagonist of 5-HT1A serotonin receptors, attenuates psychotomimetic effects of MK-801.
K Wedzony, M Maćkowiak, W Zajaczkowski, K Fijał, A Chocyk, A Czyrak
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
PMID:11027920
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Cortical localization of dopamine D4 receptors in the rat brain--immunocytochemical study.
K Wedzony, A Chocyk, M Maćkowiak, K Fijał, A Czyrak
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society,
PMID:10898094
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c-Fos proteins, induced by the serotonin receptor agonist DOI, are not expressed in 5-HT2A positive cortical neurons.
M Maćkowiak, A Chocyk, K Fijał, A Czyrak, K Wedzony
Brain research. Molecular brain research,
PMID:10521592
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Impact of metyrapone on MK-801-induced alterations in the rat dopamine D1 receptors.
A Czyrak, M Maćkowiak, K Fijał, A Chocyk, K Wedzony
Polish journal of pharmacology,
PMID:9566029
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The corticosterone synthesis inhibitor metyrapone decreases dopamine D1 receptors in the rat brain.
A Czyrak, K Wedzony, B Michalska, K Fijał, M Dziedzicka-Wasylewska, M Maćkowiak
Neuroscience,
PMID:9200731
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Prolonged treatment with antidepressants increases the 5-HT1A-mediated inhibition of hippocampal neurons without changing the 5-HT1A receptor binding.
K Tokarski, A Czyrak, M Maćkowiak, K Wedzony, M Bijak
Acta physiologica Hungarica,
PMID:9219632
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Single doses of MK-801, a non-competitive antagonist of NMDA receptors, increase the number of 5-HT1A serotonin receptors in the rat brain.
K Wedzony, M Maćkowiak, A Czyrak, K Fijał, B Michalska
Brain research,
PMID:9187317
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MP-3022, a new putative antagonist at pre- and postsynaptic 5-HT1A receptors.
E Przegaliński, M Filip, M Bijak, K Wedzony, B Budziszewska, K Tokarski, M Maćkowiak, K Fijał
Polish journal of pharmacology,
PMID:9112623
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Evidence that conditioned stress enhances outflow of dopamine in rat prefrontal cortex: a search for the influence of diazepam and 5-HT1A agonists.
K Wedzony, M Maćkowiak, K Fijał, K Gołembiowska
Synapse (New York, N.Y.),
PMID:8923664
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Ipsapirone enhances the dopamine outflow via 5-HT1A receptors in the rat prefrontal cortex.
K Wedzony, M Maćkowiak, K Fijał, K Gołembiowska
European journal of pharmacology,
PMID:8813534
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Imipramine increases the 5-HT1A receptor-mediated inhibition of hippocampal neurons without changing the 5-HT1A receptor binding.
M Bijak, K Tokarski, A Czyrak, M Maćkowiak, K Wedzony
European journal of pharmacology,
PMID:8813535
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Adaptive changes in the rat dopaminergic transmission following repeated lithium administration.
M Dziedzicka-Wasylewska, M Maćkowiak, K Fijat, K Wedzony
Journal of neural transmission (Vienna, Austria : 1996),
PMID:8872863
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The impact of a competitive and a non-competitive NMDA receptor antagonist on dopaminergic neurotransmission in the rat ventral tegmental area and substantia nigra.
K Wedzony, A Czyrak, M Maćkowiak, K Fijał
Naunyn-Schmiedeberg's archives of pharmacology,
PMID:8740145
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Structure-activity relationship studies of CNS agents. XII. 1-[4-(4-aryl-1-piperazinyl)butyl]-3,4-dihydro-2(1H)-quinolinones: new 5-HT1A, 5-HT2 and D2 ligands with a potential antipsychotic activity.
J L Mokrosz, E Chojnacka-Wójcik, A Dereń-Wesołek, A Kłodzińska, M Maćkowiak, Z Bielecka, M H Paluchowska
Drug design and discovery,
PMID:7548635
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Structure-activity relationship studies of CNS agents. Part 10(1): 1-Aryl-2-[3-(4-aryl-1-piperazinyl)propyl]-1,4-dihydro-3(2H)-isoquino linones: two modes of the interaction with the 5-HT1A receptor site.
J L Mokrosz, A J Bojarski, M Maćkowiak, Z Bielecka, J Boksa
Die Pharmazie,
PMID:8016178
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Effects of repeated treatment with fluoxetine and citalopram, 5-HT uptake inhibitors, on 5-HT1A and 5-HT2 receptors in the rat brain.
V Klimek, J Zak-Knapik, M Mackowiak
Journal of psychiatry & neuroscience : JPN,
PMID:8148368
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Structure-activity relationship studies of CNS agents. Part 9: 5-HT1A and 5-HT2 receptor affinity of some 2- and 3-substituted 1,2,3,4-tetrahydro-beta-carbolines.
A J Bojarski, M T Cegła, S Charakchieva-Minol, M J Mokrosz, M Maćkowiak, S Misztal, J L Mokrosz
Die Pharmazie,
PMID:8321880
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