Professor Krystyna Gołembiowska, PhD

Position
Professor

Department
Department of Pharmacology

lab
Team II

nfgolemb@cyf-kr.edu.pl

+48 12 6623211

room: Ojcowska

Biologist, neuropharmacologist, specialist in medical biology. Research field focused on mechanism of new neuroprotective, antidepressant, antipsychotic drugs, the role of oxidative stress in brain neurodegeneration. Lately, investigates the effects of psychoactive drugs, the so called ‘legal highs’ (in particular psychedelics, psychostimulants) on brain neurotransmission and behavior in animal models and their possible neurotoxicity. At present, the underlying mechanism of psilocybin as novel, rapid acting antidepressant.

Effect of Psilocybin and Ketamine on Brain Neurotransmitters, Glutamate Receptors, DNA and Rat Behavior. Adam Wojtas, Agnieszka Bysiek, Agnieszka Wawrzczak-Bargiela, Zuzanna Szych, Iwona Majcher-Maślanka, Monika Herian, Marzena Maćkowiak, Krystyna Gołembiowska
International journal of molecular sciences, 6713 10.3390/ijms23126713
PMID:35743159
undefined Micaela Tirri, Sabrine Bilel, Raffaella Arfè, Giorgia Corli, Beatrice Marchetti, Tatiana Bernardi, Federica Boccuto, Giovanni Serpelloni, Francesco Botrè, Fabio De-Giorgio, Krystyna Golembiowska, Matteo Marti
Frontiers in psychiatry, 10.3389/fpsyt.2022.875722
PMID:35530025
Neurotoxicological profile of the hallucinogenic compound 25I-NBOMe. Monika Herian, Adam Wojtas, Marzena Maćkowiak, Agnieszka Wawrzczak-Bargiela, Anna Solarz, Agnieszka Bysiek, Katarzyna Madej, Krystyna Gołembiowska
Scientific reports, 10.1038/s41598-022-07069-8
PMID:35190675
Neurotoxicity of MDMA: Main effects and mechanisms. Giulia Costa, Krystyna Gołembiowska
Experimental neurology, S0014-4886(21)00302-2 10.1016/j.expneurol.2021.113894
PMID:34655576
Tolerance to neurochemical and behavioral effects of the hallucinogen 25I-NBOMe. Monika Herian, Mateusz Skawski, Adam Wojtas, Małgorzata K Sobocińska, Karolina Noworyta, Krystyna Gołembiowska
Psychopharmacology, 10.1007/s00213-021-05860-5
PMID:34032876
Neurochemical and Behavioral Effects of a New Hallucinogenic Compound 25B-NBOMe in Rats. Adam Wojtas, Monika Herian, Mateusz Skawski, Małgorzata Sobocińska, Alejandro González-Marín, Karolina Noworyta-Sokołowska, Krystyna Gołembiowska
Neurotoxicity research, 10.1007/s12640-020-00297-8
PMID:33337517
Contribution of serotonin receptor subtypes to hallucinogenic activity of 25I-NBOMe and to its effect on neurotransmission. Monika Herian, Adam Wojtas, Małgorzata Katarzyna Sobocińska, Mateusz Skawski, Alejandro González-Marín, Krystyna Gołembiowska
Pharmacological reports : PR, 10.1007/s43440-020-00181-4
PMID:33174181
Functional characterization of a novel opioid, PZM21, and its effects on the behavioural responses to morphine. Lucja Kudla, Ryszard Bugno, Urszula Skupio, Lucja Wiktorowska, Wojciech Solecki, Adam Wojtas, Krystyna Golembiowska, Ferenc Zádor, Sándor Benyhe, Szymon Buda, Wioletta Makuch, Barbara Przewlocka, Andrzej J Bojarski, Ryszard Przewlocki
British journal of pharmacology, 10.1111/bph.14805
PMID:31347704
Bioanalytical methodology for determination of glutamate and aspartate for use in pharmacological sciences with application of Integrated Calibration Method. Paweł Świt, Katarzyna Kamińska, Monika Herian
Talanta, S0039-9140(19)30870-7 10.1016/j.talanta.2019.120237
PMID:31514830
Hallucinogen-Like Action of the Novel Designer Drug 25I-NBOMe and Its Effect on Cortical Neurotransmitters in Rats. Monika Herian, Adam Wojtas, Katarzyna Kamińska, Paweł Świt, Anna Wach, Krystyna Gołembiowska
Neurotoxicity research, 10.1007/s12640-019-00033-x
PMID:30989482
Methcathinone and 3-Fluoromethcathinone Stimulate Spontaneous Horizontal Locomotor Activity in Mice and Elevate Extracellular Dopamine and Serotonin Levels in the Mouse Striatum. Jakub Wojcieszak, Dariusz Andrzejczak, Adam Wojtas, Krystyna Gołembiowska, Jolanta B Zawilska
Neurotoxicity research, 10.1007/s12640-018-9973-4
PMID:30377956
Effects of exposure to 5-MeO-DIPT during adolescence on brain neurotransmission and neurotoxicity in adult rats. Karolina Noworyta-Sokołowska, Katarzyna Kamińska, Joanna Rzemieniec, Agnieszka Wnuk, Jakub Wojcieszak, Anna Maria Górska, Grzegorz Kreiner, Małgorzata Kajta, Krystyna Gołembiowska
Forensic toxicology, 10.1007/s11419-018-0433-x
PMID:30636982
The effect of chronic co-treatment with risperidone and novel antidepressant drugs on the dopamine and serotonin levels in the rats frontal cortex. Katarzyna Kamińska, Anna Górska, Karolina Noworyta-Sokołowska, Adam Wojtas, Zofia Rogóż, Krystyna Gołembiowska
Pharmacological reports : PR, S1734-1140(17)30811-3 10.1016/j.pharep.2018.04.009
PMID:30144663
The effect of chronic co-treatment with risperidone and novel antidepressant drugs on the dopamine and serotonin levels in the rats frontal cortex. Katarzyna Kamińska, Anna Górska, Karolina Noworyta-Sokołowska, Adam Wojtas, Zofia Rogóż, Krystyna Gołembiowska
Pharmacological reports : PR, 10.1016/j.pharep.2018.04.009
PMID:32002949
The Effects of Exposure to Mephedrone During Adolescence on Brain Neurotransmission and Neurotoxicity in Adult Rats. Katarzyna Kamińska, Karolina Noworyta-Sokołowska, Anna Górska, Joanna Rzemieniec, Agnieszka Wnuk, Adam Wojtas, Grzegorz Kreiner, Małgorzata Kajta, Krystyna Gołembiowska
Neurotoxicity research, 10.1007/s12640-018-9908-0
PMID:29713996
The effect of repeated-intermittent exposure to 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) during adolescence on learning and memory in adult rats. Karolina Noworyta-Sokołowska, Anna Maria Górska, Krystyna Gołembiowska
Pharmacological reports : PR, S1734-1140(17)30762-4 10.1016/j.pharep.2018.04.001
PMID:30096487
The effect of repeated-intermittent exposure to 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) during adolescence on learning and memory in adult rats. Karolina Noworyta-Sokołowska, Anna Maria Górska, Krystyna Gołembiowska
Pharmacological reports : PR, 10.1016/j.pharep.2018.04.001
PMID:32002966
Effects of the new generation α-pyrrolidinophenones on spontaneous locomotor activities in mice, and on extracellular dopamine and serotonin levels in the mouse striatum. Jakub Wojcieszak, Dariusz Andrzejczak, Adam Wojtas, Krystyna Gołembiowska, Jolanta B Zawilska
Forensic toxicology, 10.1007/s11419-018-0409-x
PMID:29963204
Neurochemical and Neurotoxic Effects of MDMA (Ecstasy) and Caffeine After Chronic Combined Administration in Mice. Anna Maria Górska, Katarzyna Kamińska, Agnieszka Wawrzczak-Bargieła, Giulia Costa, Micaela Morelli, Ryszard Przewłocki, Grzegorz Kreiner, Krystyna Gołembiowska
Neurotoxicity research, 10.1007/s12640-017-9831-9
PMID:29134560
Melatonin Supports CYP2D-Mediated Serotonin Synthesis in the Brain. Anna Haduch, Ewa Bromek, Jacek Wójcikowski, Krystyna Gołembiowska, Władysława A Daniel
Drug metabolism and disposition: the biological fate of chemicals, 10.1124/dmd.115.067413
PMID:26884482
Risperidone and escitalopram co-administration: A potential treatment of schizophrenia symptoms with less side effects. Katarzyna Kamińska, Karolina Noworyta-Sokołowska, Alexandra Jurczak, Anna Górska, Zofia Rogóż, Krystyna Gołembiowska
Pharmacological reports : PR, S1734-1140(16)30166-9 10.1016/j.pharep.2016.09.010
PMID:27755991
Neurotoxic Effects of 5-MeO-DIPT: A Psychoactive Tryptamine Derivative in Rats. Karolina Noworyta-Sokołowska, Katarzyna Kamińska, Grzegorz Kreiner, Zofia Rogóż, Krystyna Gołembiowska
Neurotoxicity research,
PMID:27461536
Neurochemical and behavioral studies on the 5-HT1A-dependent antipsychotic action of the mGlu4 receptor agonist LSP4-2022. Monika Woźniak, Krystyna Gołembiowska, Karolina Noworyta-Sokołowska, Francine Acher, Paulina Cieślik, Magdalena Kusek, Krzysztof Tokarski, Andrzej Pilc, Joanna M Wierońska
Neuropharmacology, S0028-3908(16)30278-7 10.1016/j.neuropharm.2016.06.025
PMID:27465045
The influence of aripiprazole and olanzapine on neurotransmitters level in frontal cortex of prenatally stressed rats. P Ratajczak, K Kus, K Gołembiowska, K Noworyta-Sokołowska, A Woźniak, T Zaprutko, E Nowakowska
Environmental toxicology and pharmacology, S1382-6689(16)30185-5 10.1016/j.etap.2016.07.007
PMID:27458700
NMDA Receptors on Dopaminoceptive Neurons Are Essential for Drug-Induced Conditioned Place Preference. Magdalena Sikora, Krzysztof Tokarski, Bartosz Bobula, Joanna Zajdel, Kamila Jastrzębska, Przemysław Eligiusz Cieślak, Magdalena Zygmunt, Joanna Sowa, Magdalena Smutek, Katarzyna Kamińska, Krystyna Gołembiowska, David Engblom, Grzegorz Hess, Ryszard Przewlocki, Jan Rodriguez Parkitna
eNeuro, 10.1523/ENEURO.0084-15.2016 ENEURO.0084-15.2016
PMID:27294197
Alterations of Bio-elements, Oxidative, and Inflammatory Status in the Zinc Deficiency Model in Rats. Urszula Doboszewska, Bernadeta Szewczyk, Magdalena Sowa-Kućma, Karolina Noworyta-Sokołowska, Paulina Misztak, Joanna Gołębiowska, Katarzyna Młyniec, Beata Ostachowicz, Mirosław Krośniak, Agnieszka Wojtanowska-Krośniak, Krystyna Gołembiowska, Marek Lankosz, Wojciech Piekoszewski, Gabriel Nowak
Neurotoxicity research, 10.1007/s12640-015-9571-7
PMID:26581375
Effect of Some Psychoactive Drugs Used as 'Legal Highs' on Brain Neurotransmitters. Krystyna Gołembiowska, Alexandra Jurczak, Katarzyna Kamińska, Karolina Noworyta-Sokołowska, Anna Górska
Neurotoxicity research, 10.1007/s12640-015-9569-1
PMID:26501352
5-HT7 receptor modulates GABAergic transmission in the rat dorsal raphe nucleus and controls cortical release of serotonin. Magdalena Kusek, Joanna Sowa, Katarzyna Kamińska, Krystyna Gołembiowska, Krzysztof Tokarski, Grzegorz Hess
Frontiers in cellular neuroscience, 10.3389/fncel.2015.00324
PMID:26347612
Anti-inflammatory, antioxidant, and antiparkinsonian effects of adenosine A2A receptor antagonists. Małgorzata Zygmunt, Krystyna Gołembiowska, Anna Drabczyńska, Katarzyna Kieć-Kononowicz, Jacek Sapa
Pharmacology, biochemistry, and behavior, S0091-3057(15)00061-1 10.1016/j.pbb.2015.02.020
PMID:25735490
The role of adenosine A1 and A2A receptors in the caffeine effect on MDMA-induced DA and 5-HT release in the mouse striatum. A M Górska, K Gołembiowska
Neurotoxicity research, 10.1007/s12640-014-9501-0
PMID:25391902
The role of the dorsal noradrenergic pathway of the brain (locus coeruleus) in the regulation of liver cytochrome P450 activity. Marta Kot, Anna Sadakierska-Chudy, Anna Haduch, Marta Rysz, Ewa Bromek, Krystyna Gołembiowska, Wladyslawa A Daniel
European journal of pharmacology, 10.1016/j.ejphar.2015.01.014 S0014-2999(15)00036-9
PMID:25637782
The cytochrome P450 2D-mediated formation of serotonin from 5-methoxytryptamine in the brain in vivo: a microdialysis study. Anna Haduch, Ewa Bromek, Marta Kot, Katarzyna Kamińska, Krystyna Gołembiowska, Wladyslawa A Daniel
Journal of neurochemistry, 10.1111/jnc.13031
PMID:25581337
On the role of adenosine (A)₂A receptors in cocaine-induced reward: a pharmacological and neurochemical analysis in rats. Karolina Wydra, Krystyna Gołembiowska, Agata Suder, Katarzyna Kamińska, Kjell Fuxe, Małgorzata Filip
Psychopharmacology, 10.1007/s00213-014-3675-2
PMID:25027583
The effect of risperidone on the mirtazapine-induced changes in extracellular monoamines in the rat frontal cortex. Katarzyna Kamińska, Krystyna Gołembiowska, Zofia Rogóż
Pharmacological reports : PR, 10.1016/j.pharep.2014.06.009 S1734-1140(14)00220-5
PMID:25443725
The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT1A receptor signaling: mechanistic studies. Joanna M Wierońska, Anna Sławińska, Magdalena Łasoń-Tyburkiewicz, Piotr Gruca, Mariusz Papp, Stevin H Zorn, Darío Doller, Natalia Kłeczek, Karolina Noworyta-Sokołowska, Krystyna Gołembiowska, Andrzej Pilc
Psychopharmacology, 10.1007/s00213-014-3657-4
PMID:25012236
LPS-induced oxidative stress and inflammatory reaction in the rat striatum. Karolina Noworyta-Sokołowska, Anna Górska, Krystyna Gołembiowska
Pharmacological reports : PR,
PMID:24145080
Group III mGlu receptor agonist, ACPT-I, exerts potential neuroprotective effects in vitro and in vivo. Helena Domin, Krystyna Gołembiowska, Danuta Jantas, Katarzyna Kamińska, Barbara Zięba, Maria Smiałowska
Neurotoxicity research, 10.1007/s12640-013-9455-7
PMID:24402869
The effect of caffeine on MDMA-induced hydroxyl radical production in the mouse striatum. Anna Maria Górska, Karolina Noworyta-Sokołowska, Krystyna Gołembiowska
Pharmacological reports : PR, 10.1016/j.pharep.2014.03.003 S1734-1140(14)00089-9
PMID:24948078
Effect of risperidone on the fluoxetine-induced changes in extracellular dopamine, serotonin and noradrenaline in the rat frontal cortex. Katarzyna Kamińska, Krystyna Gołembiowska, Zofia Rogóż
Pharmacological reports : PR,
PMID:24399710
A partial lesion of the substantia nigra pars compacta and retrorubral field decreases the harmaline-induced glutamate release in the rat cerebellum. Krystyna Gołembiowska, Klemencja Berghauzen-Maciejewska, Anna Górska, Katarzyna Kamińska, Krystyna Ossowska
Brain research, 10.1016/j.brainres.2013.08.059 S0006-8993(13)01214-6
PMID:24012623
The role of brain noradrenergic system in the regulation of liver cytochrome P450 expression. Anna Sadakierska-Chudy, Anna Haduch, Marta Rysz, Krystyna Gołembiowska, Władysława A Daniel
Biochemical pharmacology, 10.1016/j.bcp.2013.07.017 S0006-2952(13)00453-X
PMID:23924605
Accumbal and pallidal dopamine, glutamate and GABA overflow during cocaine self-administration and its extinction in rats. Karolina Wydra, Krystyna Golembiowska, Magdalena Zaniewska, Katarzyna Kamińska, Luca Ferraro, Kjell Fuxe, Małgorzata Filip
Addiction biology, 10.1111/adb.12031
PMID:23311632
Novelty-seeking behaviors and the escalation of alcohol drinking after abstinence in mice are controlled by metabotropic glutamate receptor 5 on neurons expressing dopamine d1 receptors. Jan Rodriguez Parkitna, Magdalena Sikora, Sławomir Gołda, Krystyna Gołembiowska, Beata Bystrowska, David Engblom, Ainhoa Bilbao, Ryszard Przewlocki
Biological psychiatry, 10.1016/j.biopsych.2012.07.019 S0006-3223(12)00631-2
PMID:22902169
Effects of adenosine receptor antagonists on the in vivo LPS-induced inflammation model of Parkinson's disease. Krystyna Gołembiowska, Jadwiga Wardas, Karolina Noworyta-Sokołowska, Katarzyna Kamińska, Anna Górska
Neurotoxicity research, 10.1007/s12640-012-9372-1
PMID:23296550
Glutamate input to noradrenergic neurons plays an essential role in the development of morphine dependence and psychomotor sensitization. Jan Rodriguez Parkitna, Wojciech Solecki, Krystyna Gołembiowska, Krzysztof Tokarski, Jakub Kubik, Sławomir Gołda, Martin Novak, Rosanna Parlato, Grzegorz Hess, Rolf Sprengel, Ryszard Przewłocki
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), 10.1017/S1461145711001568
PMID:22040728
The effect of adenosine A(2A) receptor antagonists on hydroxyl radical, dopamine, and glutamate in the striatum of rats with altered function of VMAT2. Krystyna Gołembiowska, Anna Dziubina
Neurotoxicity research, 10.1007/s12640-012-9316-9
PMID:22407500
Pharmacological characterization of the norepinephrine and dopamine reuptake inhibitor EB-1020: implications for treatment of attention-deficit hyperactivity disorder. Frank P Bymaster, Krystyna Golembiowska, Magdalena Kowalska, Yong Kee Choi, Frank I Tarazi
Synapse (New York, N.Y.), 10.1002/syn.21538
PMID:22298359
Effects of the triple reuptake inhibitor amitifadine on extracellular levels of monoamines in rat brain regions and on locomotor activity. Krystyna Golembiowska, Magdalena Kowalska, Frank P Bymaster
Synapse (New York, N.Y.), 10.1002/syn.21531
PMID:22213370
Partial lesion of the dopaminergic innervation of the ventral striatum induces Katarzyna Kuter, Wacław Kolasiewicz, Krystyna Gołembiowska, Anna Dziubina, Gert Schulze, Klemencja Berghauzen, Jadwiga Wardas, Krystyna Ossowska
Pharmacological reports : PR,
PMID:22358086
Effect of adenosine A(2A) receptor antagonists and L-DOPA on hydroxyl radical, glutamate and dopamine in the striatum of 6-OHDA-treated rats. Krystyna Gołembiowska, Anna Dziubina
Neurotoxicity research, 10.1007/s12640-011-9263-x
PMID:21830163
Selective mGluR1 antagonist EMQMCM inhibits the kainate-induced excitotoxicity in primary neuronal cultures and in the rat hippocampus. Maria Śmiałowska, Krystyna Gołembiowska, Małgorzata Kajta, Barbara Zięba, Anna Dziubina, Helena Domin
Neurotoxicity research, 10.1007/s12640-011-9293-4
PMID:22144346
Cytochrome P450 mediates dopamine formation in the brain in vivo. Ewa Bromek, Anna Haduch, Krystyna Gołembiowska, Władysława A Daniel
Journal of neurochemistry, 10.1111/j.1471-4159.2011.07339.x
PMID:21651557
Effect of metyrapone on the fluoxetine-induced change in extracellular dopamine, serotonin and their metabolites in the rat frontal cortex. Zofia Rogóż, Krystyna Gołembiowska
Pharmacological reports : PR,
PMID:21273658
Neuroprotective potential of mGluR5 antagonist MTEP: effects on kainate-induced excitotoxicity in the rat hippocampus. Helena Domin, Barbara Zięba, Krystyna Gołembiowska, Magdalena Kowalska, Anna Dziubina, Maria Śmiałowska
Pharmacological reports : PR,
PMID:21273662
Effects of low doses of intracerebroventricular 6-OHDA on the levels of monoaminergic neurotransmitters in rat brain structures. Anna Sadakierska-Chudy, Anna Haduch, Krystyna Gołembiowska, Władysława A Daniel
Pharmacological reports : PR,
PMID:21273682
Prenatal lipopolysaccharide treatment enhances MK-801-induced psychotomimetic effects in rats. A Basta-Kaim, K Fijał, B Budziszewska, M Regulska, M Leśkiewicz, M Kubera, K Gołembiowska, W Lasoń, K Wędzony
Pharmacology, biochemistry, and behavior, 10.1016/j.pbb.2010.12.026
PMID:21236292
Effect of venlafaxine and nicotine on the level of neurotransmitters and their metabolites in rat brains. A Czubak, E Nowakowska, K Golembiowska, K Kus, K Burda, J Metelska
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society,
PMID:20610865
Increased reactive oxygen species production in the brain after repeated low-dose pesticide paraquat exposure in rats. A comparison with peripheral tissues. Katarzyna Kuter, Przemysław Nowak, Krystyna Gołembiowska, Krystyna Ossowska
Neurochemical research, 10.1007/s11064-010-0163-x
PMID:20369291
Chronic treatment with zinc and antidepressants induces enhancement of presynaptic/extracellular zinc concentration in the rat prefrontal cortex. Magdalena Sowa-Kućma, Magdalena Kowalska, Marek Szlósarczyk, Krystyna Gołembiowska, Włodzimierz Opoka, Bogusław Baś, Andrzej Pilc, Gabriel Nowak
Amino acids, 10.1007/s00726-010-0641-0
PMID:20532950
Mazindol attenuates ketamine-induced cognitive deficit in the attentional set shifting task in rats. Agnieszka Nikiforuk, Krystyna Gołembiowska, Piotr Popik
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 10.1016/j.euroneuro.2009.08.001
PMID:19729284
The involvement of NMDA and AMPA receptors in the mechanism of antidepressant-like action of zinc in the forced swim test. B Szewczyk, E Poleszak, M Sowa-Kućma, A Wróbel, S Słotwiński, J Listos, P Wlaź, A Cichy, A Siwek, M Dybała, K Gołembiowska, A Pilc, Gabriel Nowak
Amino acids, 10.1007/s00726-009-0412-y
PMID:19956994
Treatment with 1,2,3,4,-tetrahydroisoquinoline affects glutamate release in the striatum but not the binding of [3H]MK-801 to NMDA receptors in the dopaminergic structures of the rat brain. Elzbieta Lorenc-Koci, Krystyna Gołembiowska, Małgorzata Pietraszek, Jadwiga Wardas
Pharmacological reports : PR,
PMID:19904002
1-Methyl-1,2,3,4-tetrahydroisoquinoline antagonizes a rise in brain dopamine metabolism, glutamate release in frontal cortex and locomotor hyperactivity produced by MK-801 but not the disruptions of prepulse inhibition, and impairment of working memory in rat. Małgorzata Pietraszek, Jerzy Michaluk, Irena Romańska, Agnieszka Wasik, Krystyna Gołembiowska, Lucyna Antkiewicz-Michaluk
Neurotoxicity research, 10.1007/s12640-009-9097-y
PMID:19649683
Preclinical evaluation of the abuse potential of the analgesic bicifadine. Katherine L Nicholson, Robert L Balster, Krystyna Golembiowska, Magdalena Kowalska, Joseph P Tizzano, Phil Skolnick, Anthony S Basile
The Journal of pharmacology and experimental therapeutics, 10.1124/jpet.109.150540
PMID:19357320
Effect of adenosine A(2A) receptor antagonists on L-DOPA-induced hydroxyl radical formation in rat striatum. Krystyna Gołembiowska, Anna Dziubina, Magdalena Kowalska, Katarzyna Kamińska
Neurotoxicity research, 10.1007/s12640-009-9016-2
PMID:19384578
Dopamine in the Turkey retina-an impact of environmental light, circadian clock, and melatonin. Anna Lorenc-Duda, Małgorzata Berezińska, Anna Urbańska, Krystyna Gołembiowska, Jolanta B Zawilska
Journal of molecular neuroscience : MN, 10.1007/s12031-008-9153-8
PMID:18953673
Intraperitoneal zinc administration increases extracellular zinc in the rat prefrontal cortex. W Opoka, M Sowa-Kućma, M Kowalska, B Baś, K Gołembiowska, G Nowak
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society,
PMID:18953091
Paradoxical effects of adenosine receptor ligands on hydroxyl radical generation by L-DOPA in the rat striatum. Krystyna Gołembiowska, Anna Dziubina, Magdalena Kowalska, Katarzyna Kamińska
Pharmacological reports : PR,
PMID:18622056
Regulation of liver cytochrome P450 by activation of brain dopaminergic system: physiological and pharmacological implications. Jacek Wójcikowski, Krystyna Gołembiowska, Władysława Anna Daniel
Biochemical pharmacology, 10.1016/j.bcp.2008.04.016
PMID:18538745
Anxiolytic-like action of MTEP expressed in the conflict drinking Vogel test in rats is serotonin dependent. K Stachowicz, K Gołembiowska, M Sowa, G Nowak, E Chojnacka-Wójcik, A Pilc
Neuropharmacology,
PMID:17870136
The regulation of liver cytochrome p450 by the brain dopaminergic system. Jacek Wójcikowski, Krystyna Gołembiowska, Władysława Anna Daniel
Current drug metabolism,
PMID:17691922
Characterization of the antinociceptive actions of bicifadine in models of acute, persistent, and chronic pain. Anthony S Basile, Aaron Janowsky, Krystyna Golembiowska, Magdalena Kowalska, Eyal Tam, Morris Benveniste, Piotr Popik, Agnieszka Nikiforuk, Martyna Krawczyk, Gabriel Nowak, Philip A Krieter, Arnold S Lippa, Phil Skolnick, Elena Koustova
The Journal of pharmacology and experimental therapeutics,
PMID:17325229
Pharmacological profile of the Piotr Popik, Martyna Krawczyk, Krystyna Golembiowska, Gabriel Nowak, Aaron Janowsky, Phil Skolnick, Arnold Lippa, Anthony S Basile
Cellular and molecular neurobiology,
PMID:16636898
Glutamate concentration in whole saliva and taste responses to monosodium glutamate in humans. A Scinska-Bienkowska, E Wrobel, D Turzynska, A Bidzinski, E Jezewska, H Sienkiewicz-Jarosz, K Golembiowska, W Kostowski, A Kukwa, A Plaznik, P Bienkowski
Nutritional neuroscience,
PMID:16910167
The mechanism of 1,2,3,4-tetrahydroisoquinolines neuroprotection: the importance of free radicals scavenging properties and inhibition of glutamate-induced excitotoxicity. Lucyna Antkiewicz-Michaluk, Jerzy W Lazarewicz, Antoni Patsenka, Malgorzata Kajta, Elzbieta Zieminska, Elzbieta Salinska, Agnieszka Wasik, Krystyna Golembiowska, Jerzy Vetulani
Journal of neurochemistry,
PMID:16515537
1,2,3,4-Tetrahydroisoquinoline protects terminals of dopaminergic neurons in the striatum against the malonate-induced neurotoxicity. Elzbieta Lorenc-Koci, Krystyna Gołembiowska, Jadwiga Wardas
Brain research,
PMID:16004976
In-vivo effects of the 1,2,4-piperazine derivatives MM5 and MC1, putative 5-HT agonists, on dopamine and serotonin release in rat prefrontal cortex. Joanna Iskra-Jopa, Krystyna Gołembiowska, Anna Dziubina, Marcin Cybulski, Beata Duszyńska, Zdzisław Chilmonczyk
The Journal of pharmacy and pharmacology,
PMID:15720784
Striatal adenosine A(2A) receptor blockade increases extracellular dopamine release following l-DOPA administration in intact and dopamine-denervated rats. Krystyna Gołembiowska, Anna Dziubina
Neuropharmacology,
PMID:15275831
The role of striatal metabotropic glutamate receptors in Parkinson's disease. K Ossowska, J Konieczny, J Wardas, K Gołembiowska, S Wolfarth, A Pilc
Amino acids,
PMID:12373537
The role of striatal metabotropic glutamate receptors in degeneration of dopamine neurons: review article. K Gołembiowska, J Konieczny, K Ossowska, S Wolfarth
Amino acids,
PMID:12373538
Effect of the adenosine A2A receptor antagonist 8-(3-chlorostyryl)caffeine on L-DOPA biotransformation in rat striatum. Krystyna Gołembiowska, Anna Dziubina
Brain research,
PMID:14751592
Neuroprotective action of MPEP, a selective mGluR5 antagonist, in methamphetamine-induced dopaminergic neurotoxicity is associated with a decrease in dopamine outflow and inhibition of hyperthermia in rats. K Gołembiowska, J Konieczny, S Wolfarth, K Ossowska
Neuropharmacology,
PMID:12907309
Inhibition of amino acid release by 5-HT1B receptor agonist in the rat prefrontal cortex. Krystyna Gołembiowska, Anna Dziubina
Polish journal of pharmacology,
PMID:12866717
Pharmacological characterization of MP349, a novel 5-HT1A-receptor antagonist with anxiolytic-like activity, in mice and rats. Anna Wesołowska, Maria H Paluchowska, Krystyna Gołembiowska, Ewa Chojnacka-Wójcik
The Journal of pharmacy and pharmacology,
PMID:12803776
Differential effects of chronic haloperidol and clozapine administration on glutamatergic transmission in the fronto-parietal cortex in rats: microdialysis and electrophysiological studies. Małgorzata Pietraszek, Krystyna Gołembiowska, Maria Bijak, Krystyna Ossowska, Stanislaw Wolfarth
Naunyn-Schmiedeberg's archives of pharmacology,
PMID:12382070
Involvement of adenosine in the effect of antidepressants on glutamate and aspartate release in the rat prefrontal cortex. K Gołembiowska, A Dziubina
Naunyn-Schmiedeberg's archives of pharmacology,
PMID:11414661
Effect of acute and chronic administration of citalopram on glutamate and aspartate release in the rat prefrontal cortex. K Gołembiowska, A Dziubina
Polish journal of pharmacology,
PMID:11334237
Effect of adenosine kinase, adenosine deaminase and transport inhibitors on striatal dopamine and stereotypy after methamphetamine administration. K Gołembiowska, A Zylewska
Neuropharmacology,
PMID:10963755
Effect of acute and chronic administration of 1,2,3,4-tetrahydroisoquinoline on muscle tone, metabolism of dopamine in the striatum and tyrosine hydroxylase immunocytochemistry in the substantia nigra, in rats. E Lorenc-Koci, M Smiałowska, L Antkiewicz-Michaluk, K Gołembiowska, M Bajkowska, S Wolfarth
Neuroscience,
PMID:10682712
Effect of antidepressant drugs on veratridine-evoked glutamate and aspartate release in rat prefrontal cortex. K Gołembiowska, A Zylewska
Polish journal of pharmacology,
PMID:10389146
N6-2-(4-aminophenyl)ethyladenosine (APNEA), a putative adenosine A3 receptor agonist, enhances methamphetamine-induced dopamine outflow in rat striatum. K Gołembiowska, A Zylewska
Polish journal of pharmacology,
PMID:10091714
Agonists of A1 and A2A adenosine receptors attenuate methamphetamine-induced overflow of dopamine in rat striatum. K Golembiowska, A Zylewska
Brain research,
PMID:9739141
Effect of EMD 57445, the selective sigma receptor ligand, on the turnover and release of dopamine. G Skuza, K Gołembiowska, K Wedzony
Polish journal of pharmacology,
PMID:9662740
EMD 57445, the selective sigma receptor ligand, has no effect on the 5-hydroxytryptamine system. G Skuza, Z Rogóz, K Gołembiowska
Polish journal of pharmacology,
PMID:9566054
Adenosine receptors--the role in modulation of dopamine and glutamate release in the rat striatum. K Gołembiowska, A Zylewska
Polish journal of pharmacology,
PMID:9566030
Evidence that conditioned stress enhances outflow of dopamine in rat prefrontal cortex: a search for the influence of diazepam and 5-HT1A agonists. K Wedzony, M Maćkowiak, K Fijał, K Gołembiowska
Synapse (New York, N.Y.),
PMID:8923664
Ipsapirone enhances the dopamine outflow via 5-HT1A receptors in the rat prefrontal cortex. K Wedzony, M Maćkowiak, K Fijał, K Gołembiowska
European journal of pharmacology,
PMID:8813534
Adenosine kinase inhibitors augment release of adenosine from spinal cord slices. K Golembiowska, T D White, J Sawynok
European journal of pharmacology,
PMID:8832217
Modulation of adenosine release from rat spinal cord by adenosine deaminase and adenosine kinase inhibitors. K Golembiowska, T D White, J Sawynok
Brain research,
PMID:8616636
Differential effects of CGP 37849 and MK-801, competitive and noncompetitive NMDA antagonists, with respect to the modulation of sensorimotor gating and dopamine outflow in the prefrontal cortex of rats. K Wedzony, K Gołembiowska, M Zazula
Naunyn-Schmiedeberg's archives of pharmacology,
PMID:7870195
Central effects of repeated treatment with CGP 37849, a competitive NMDA receptor antagonist with potential antidepressant activity. J Maj, V Klimek, K Gołembiowska, Z Rogóz, G Skuza
Polish journal of pharmacology,
PMID:7912134
Concomitant administration of MK-801 and desipramine enhances extracellular concentration of dopamine in the rat prefrontal cortex. K Wedzony, K Gołembiowska
Neuroreport,
PMID:8280864
MK-801-induced symptoms of sensitization. The lack of correlation with the extracellular concentration of dopamine in the rat prefrontal cortex. K Wedzony, K Gołembiowska, V Klimek
Brain research,
PMID:8275316
MK-801 elevates the extracellular concentration of dopamine in the rat prefrontal cortex and increases the density of striatal dopamine D1 receptors. K Wedzony, V Klimek, K Gołembiowska
Brain research,
PMID:8242376
Enhancement by ipsapirone of dopamine release in the rat striatum. K Gołembiowska, K Wedzony
Polish journal of pharmacology,
PMID:7693136
Effect of acute and chronic treatment of rats with the putative anxiolytic drug ipsapirone on the turnover of monoamine transmitters in various brain regions. A comparison with the 5-HT1A agonist 8-OH-DPAT. K Gołembiowska
Polish journal of pharmacology and pharmacy,
PMID:1359515
The effect of p-chloroamphetamine and p-chlorophenylalanine on the level of thyrotropin-releasing hormone and its receptors in some brain structures and lumbar spinal cord of the rat. E Przegaliński, L Jaworska, K Gołembiowska
Neuropeptides,
PMID:1383865
Melatonin increases serotonin N-acetyltransferase activity and decreases dopamine synthesis in light-exposed chick retina: in vivo evidence supporting melatonin-dopamine interaction in retina. J Z Nowak, A Kazula, K Gołembiowska
Journal of neurochemistry,
PMID:1402901
Serotonin, dopamine, noradrenaline and their metabolites: levels in the brain of the house cricket (Acheta domesticus L.) during a 24-hour period and after administration of quipazine--a 5-HT2 receptor agonist. E Pyza, K Gołembiowska, L Antkiewicz-Michaluk
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology,
PMID:1687530
Involvement of 5-HT1A receptors in the antidepressant-like activity of gepirone in the forced swimming test in rats. E Chojnacka-Wójcik, E Tatarczyńska, K Gołembiowska, E Przegaliński
Neuropharmacology,
PMID:1681449
The role of dopamine in regulation of thyrotropin-releasing hormone in the striatum and nucleus accumbens of the rat. E Przegaliński, L Jaworska, R Konarska, K Gołembiowska
Neuropeptides,
PMID:1680223
Ipsapirone, a new anxiolytic drug, stimulates catecholamine turnover in various regions of the rat brain. K Gołembiowska
Polish journal of pharmacology and pharmacy,
PMID:1980361
The effect of fenfluramine on the thyrotropin-releasing hormone (TRH) content in the rat brain structures and lumbar spinal cord. E Przegaliński, L Jaworska, K Gołembiowska
Neuropeptides,
PMID:2124333
Lateral hypothalamus-zona incerta region as an output station for the catalepsy induced by the blockade of striatal D1 and D2 dopamine receptors. K Ossowska, J Wardas, K Golembiowska, S Wolfarth
Brain research,
PMID:2154287
Effects of ipsapirone on the level of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in some regions of the rat brain. K Gołembiowska
Polish journal of pharmacology and pharmacy,
PMID:2479937
Evidence for increased apomorphine-sensitive dopaminergic effects after acute treatment with morphine. J Scheel-Krüger, K Golembiowska, E Mogilnicka
Psychopharmacology,
PMID:407614
Correction to: the Effects of Exposure to Mephedrone During Adolescence on Brain Neurotransmission and Neurotoxicity in Adult Rats. Katarzyna Kamińska, Karolina Noworyta-Sokołowska, Anna Górska, Joanna Rzemieniec, Agnieszka Wnuk, Adam Wojtas, Grzegorz Kreiner, Małgorzata Kajta, Krystyna Gołembiowska
,
PMID:30905052
Hallucinogenic activity, neurotransmitters release, anxiolytic and neurotoxic effects in Rat's brain following repeated administration of novel psychoactive compound 25B-NBOMe. Adam Wojtas, Monika Herian, Marzena Maćkowiak, Anna Solarz, Agnieszka Wawrzczak-Bargiela, Agnieszka Bysiek, Karolina Noworyta, Krystyna Gołembiowska
,
PMID:37689261
Introduction to the thematic collection Krystyna Gołembiowska
,
PMID:37904067
The possible place for psychedelics in pharmacotherapy of mental disorders. Adam Wojtas
,
PMID:37934320
Limbic System Response to Psilocybin and Ketamine Administration in Rats: A Neurochemical and Behavioral Study. Adam Wojtas, Agnieszka Bysiek, Agnieszka Wawrzczak-Bargiela, Marzena Maćkowiak, Krystyna Gołembiowska
,
PMID:38203271
Molecular and Medical Aspects of Psychedelics. Adam Wojtas, Krystyna Gołembiowska
,
PMID:38203411

More publications

GOŁEMBIOWSKA K.: Pharmacology and Neurotoxicity of 5-MeO-DIPT. In: Kostrzewa R.M. (eds) Handbook of Neurotoxicity. Springer, Cham, 2021, 1-12.
Effects of Synthetic Cathinones on Brain Neurotransmitters. GOŁEMBIOWSKA K., KAMIŃSKA K. Effects of Synthetic Cathinones on Brain Neurotransmitters. In: Zawilska J. B. (ed.) Synthetic Cathinones. Current Topics in Neurotoxicity 12. Springer International Publishing AG, Cham, 2018, p. 117-124.
Tirri Micaela, Bilel Sabrine, Arfè Raffaella, Corli Giorgia, Marchetti Beatrice, Bernardi Tatiana, Boccuto Federica, Serpelloni Giovanni, Botrè Francesco, De-Giorgio Fabio, Golembiowska Krystyna, Marti Mateo. Effect of –NBOMe Compounds on sensorimotor, motor, and prepulse inhibition responses in mice in comparison with the 2C analogs and Lysergic Acid Diethylamide: from preclinical evidence to forensic implication in driving under the influence of drugs. Front. Psychiatry, April 2022, 13, 875722. https://doi.org/10.3389/fpsyt.2022.875722
GOŁEMBIOWSKA K., KAMIŃSKA K. Effects of Synthetic Cathinones on Brain Neurotransmitters. In: Zawilska J. B. (ed.) Synthetic Cathinones. Current Topics in Neurotoxicity 12. Springer International Publishing AG, Cham, 2018, p. 117-124.

Neurochemical basis of antidepressive properties of psychedelics in rodent model of depression OPUS 19 2020/37/B/NZ7/03753 - 2020-11-20 - 2024-11-20
Neurochemical basis of antidepressive properties of psychedelics in rodent model of depression
Pharmacological properties and neurotoxicity of novel NBOMe derivatives - 2017-01-27 - 2020-01-26
OPUS11 2016/21/B/NZ7/01131

Professor Krystyna Gołembiowska, PhD

National

International

interests

techniques

keywords

contact

links

Website editor