Wojciech Kuban, PhD
Adjunct
I have devoted my professional career to developing proven research innovation because I find pleasure in discovery. The opportunity to learn a new things and ideas would always an extra reward for me.
I have background as an accomplished know-how scientist with 15+ years of experience delivering complex solutions for top organizations in the technology, healthcare, and pharmaceutical GMP quality assurance sectors as Charles River Ireland (Drug Validation and Development), Selvita Poland (Drug Development), National Institutes of Health, Bethesda USA (DNA Repair and Metabolism), A*STAR - Agency for Science, Technology and Research, Singapore and Children's Medical Research Institute, Australia (Gene Therapy AAV).
My present research is driven by the desire to create safer and more effective medical therapy for neurological and psychiatric conditions.
I am interested in process of drug delivery and metabolism in the human brain. My work focuses on tissue culture engineering and on creating methods for observing pathway stages of drugs within the cerebral tissue: absorption, distribution, metabolism, and excretion.
Mine intention is make discovery and development the most economical, transportable, and accessible methods for neurological disorder prevention.
I believe in collaborative environment that promotes the free exchange of ideas and encourages creative blending of technology and modern biological science.
I am always gratified to educate a future generation of biotechnologist and biomedical engineers.
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Cytochrome P450 expression and regulation in the brain.
Wojciech Kuban, Władysława Anna Daniel
Drug metabolism reviews, 10.1080/03602532.2020.1858856
PMID:33356626 -
Replication fidelity in E. coli: Differential leading and lagging strand effects for dnaE antimutator alleles.
Karolina Makiela-Dzbenska, Katarzyna H Maslowska, Wojciech Kuban, Damian Gawel, Piotr Jonczyk, Roel M Schaaper, Iwona J Fijalkowska
DNA repair, S1568-7864(19)30163-6 10.1016/j.dnarep.2019.102643
PMID:31324532 -
Removal of misincorporated ribonucleotides from prokaryotic genomes: an unexpected role for nucleotide excision repair.
Alexandra Vaisman, John P McDonald, Donald Huston, Wojciech Kuban, Lili Liu, Bennett Van Houten, Roger Woodgate
PLoS genetics, 10.1371/journal.pgen.1003878
PMID:24244177 -
Mechanisms employed by Escherichia coli to prevent ribonucleotide incorporation into genomic DNA by Pol V.
John P McDonald, Alexandra Vaisman, Wojciech Kuban, Myron F Goodman, Roger Woodgate
PLoS genetics, 10.1371/journal.pgen.1003030
PMID:23144626 -
Escherichia coli UmuC active site mutants: effects on translesion DNA synthesis, mutagenesis and cell survival.
Wojciech Kuban, Alexandra Vaisman, John P McDonald, Kiyonobu Karata, Wei Yang, Myron F Goodman, Roger Woodgate
DNA repair, 10.1016/j.dnarep.2012.06.005
PMID:22784977