Karolina Przepiórska-Drońska, MSc
Position
Laboratory technical assistant with higher education
Laboratory technical assistant with higher education
Department
Department of Drug Addiction Pharmacology
Department of Drug Addiction Pharmacology
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Amorfrutin B Protects Mouse Brain Neurons from Hypoxia/Ischemia by Inhibiting Apoptosis and Autophagy Processes Through Gene Methylation- and miRNA-Dependent Regulation.
Karolina Przepiórska, Agnieszka Wnuk, Cordian Beyer, Małgorzata Kajta
Molecular neurobiology, 10.1007/s12035-022-03087-9
PMID:36324052 -
Prenatal Exposure to Triclocarban Impairs ESR1 Signaling and Disrupts Epigenetic Status in Sex-Specific Ways as Well as Dysregulates the Expression of Neurogenesis- and Neurotransmitter-Related Genes in the Postnatal Mouse Brain.
Agnieszka Wnuk, Joanna Rzemieniec, Karolina Przepiórska, Bernadeta Angelika Pietrzak, Marzena Maćkowiak, Małgorzata Kajta
International journal of molecular sciences, 13121 10.3390/ijms222313121
PMID:34884933 -
Posttreatment Strategy Against Hypoxia and Ischemia Based on Selective Targeting of Nonnuclear Estrogen Receptors with PaPE-1.
A Wnuk, K Przepiórska, B A Pietrzak, M Kajta
Neurotoxicity research, 10.1007/s12640-021-00441-y
PMID:34797527 -
Post-Treatment with Amorfrutin B Evokes PPARγ-Mediated Neuroprotection against Hypoxia and Ischemia.
Agnieszka Wnuk, Karolina Przepiórska, Bernadeta A Pietrzak, Małgorzata Kajta
Biomedicines, 854 10.3390/biomedicines9080854
PMID:34440058 -
Selective Targeting of Non-nuclear Estrogen Receptors with PaPE-1 as a New Treatment Strategy for Alzheimer's Disease.
Agnieszka Wnuk, Karolina Przepiórska, Joanna Rzemieniec, Bernadeta Pietrzak, Małgorzata Kajta
Neurotoxicity research, 10.1007/s12640-020-00289-8
PMID:33025361
- A popular-science article "From birth to old age - amorfrutin B in neuroprotection" Karolina Przepiórska
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Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer’s disease - 2023-01-01 - 2026-01-01
NCN PRELUDIUM Grant; 2022/45/N/NZ7/01418; 2023-2026. Ongoing.
Principal Investigator of the grant: Karolina PrzepiórskaThe scientific supervisor of the grant: Professor Małgorzata Kajta
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The first place in the competition for a popular-science article "From birth to old age - amorfrutin B in neuroprotection" - the Organizer: board of Directors of the Maj Institute of Pharmacology of the Polish Academy of Sciences.
2021-09-30
interests
keywords
- animal models
- apoptosis
- asphyxia
- Benzophenone-3
- DDE
- DDT
- epigenetics
- excitotoxicity
- frontal cortex
- gene expression
- hippocampus
- hypoxia
- hypoxia
- ischemia
- miRNA
- molecular biology
- necrosis
- neurodegeneration
- neuroprotection
- neurotoxicity
- peroxisome proliferator-activated receptors – PPARs
- pharmacotherapy
- primary neuronal cell cultures
- retinoid X receptors – RXRs
- selective aryl hydrocarbon receptor modulators – SAhRMs
- selective estrogen receptor modulators – SERMs
- selective nuclear receptor modulators
- stroke