Joanna Wierońska, PhD
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Involvement of GABAB Receptor Signaling in Antipsychotic-like Action of the Novel Orthosteric Agonist of the mGlu4 Receptor, LSP4-2022.
Monika Woźniak, Francine Acher, Marcin Marciniak, Magdalena Lasoń-Tyburkiewicz, Piotr Gruca, Mariusz Papp, Andrzej Pilc, Joanna M Wierońska
Current neuropharmacology,
PMID:26769224
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Neurochemical and behavioral studies on the 5-HT1A-dependent antipsychotic action of the mGlu4 receptor agonist LSP4-2022.
Monika Woźniak, Krystyna Gołembiowska, Karolina Noworyta-Sokołowska, Francine Acher, Paulina Cieślik, Magdalena Kusek, Krzysztof Tokarski, Andrzej Pilc, Joanna M Wierońska
Neuropharmacology, S0028-3908(16)30278-7 10.1016/j.neuropharm.2016.06.025
PMID:27465045
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Metabotropic glutamate receptors as targets for new antipsychotic drugs: Historical perspective and critical comparative assessment.
Joanna M Wierońska, Stevin H Zorn, Dario Doller, Andrzej Pilc
Pharmacology & therapeutics, S0163-7258(15)00199-0 10.1016/j.pharmthera.2015.10.007
PMID:26549541
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mGlu₅-GABAB interplay in animal models of positive, negative and cognitive symptoms of schizophrenia.
Joanna M Wierońska, Natalia Kłeczek, Monika Woźniak, Piotr Gruca, Magdalena Łasoń-Tyburkiewicz, Mariusz Papp, Piotr Brański, Grzegorz Burnat, Andrzej Pilc
Neurochemistry international, 10.1016/j.neuint.2015.03.010 S0197-0186(15)00061-3
PMID:25863284
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Is the mGlu5 receptor a possible target for new antidepressant drugs?
Agnieszka Pałucha-Poniewiera, Joanna M Wierońska, Piotr Brański, Grzegorz Burnat, Barbara Chruścicka, Andrzej Pilc
Pharmacological reports : PR,
PMID:24552998
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The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT1A receptor signaling: mechanistic studies.
Joanna M Wierońska, Anna Sławińska, Magdalena Łasoń-Tyburkiewicz, Piotr Gruca, Mariusz Papp, Stevin H Zorn, Darío Doller, Natalia Kłeczek, Karolina Noworyta-Sokołowska, Krystyna Gołembiowska, Andrzej Pilc
Psychopharmacology, 10.1007/s00213-014-3657-4
PMID:25012236
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The antidepressant-like action of mGlu5 receptor antagonist, MTEP, in the tail suspension test in mice is serotonin dependent.
Agnieszka Pałucha-Poniewiera, Piotr Brański, Joanna M Wierońska, Katarzyna Stachowicz, Anna Sławińska, Andrzej Pilc
Psychopharmacology,
PMID:23958941
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The antipsychotic-like effects of positive allosteric modulators of metabotropic glutamate mGlu4 receptors in rodents.
Anna Sławińska, Joanna M Wierońska, Katarzyna Stachowicz, Marcin Marciniak, Magdalena Lasoń-Tyburkiewicz, Piotr Gruca, Mariusz Papp, Magdalena Kusek, Krzysztof Tokarski, Darío Doller, Andrzej Pilc
British journal of pharmacology, 10.1111/bph.12254
PMID:23714045
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The reversal of cognitive, but not negative or positive symptoms of schizophrenia, by the mGlu₂/₃ receptor agonist, LY379268, is 5-HT₁A dependent.
Joanna M Wierońska, A Sławińska, K Stachowicz, M Łasoń-Tyburkiewicz, P Gruca, M Papp, A Pilc
Behavioural brain research, 10.1016/j.bbr.2013.08.007 S0166-4328(13)00483-X
PMID:23948211
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Glutamate-based anxiolytic ligands in clinical trials.
Joanna M Wierońska, Andrzej Pilc
Expert opinion on investigational drugs, 10.1517/13543784.2013.803066
PMID:23718208
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The antipsychotic-like effects of the mGlu group III orthosteric agonist, LSP1-2111, involves 5-HT₁A signalling.
Joanna M Wierońska, Francine C Acher, Anna Sławińska, Piotr Gruca, Magdalena Lasoń-Tyburkiewicz, Mariusz Papp, Andrzej Pilc
Psychopharmacology, 10.1007/s00213-013-3005-0
PMID:23474845
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Glutamate-based antidepressants: preclinical psychopharmacology.
Andrzej Pilc, Joanna M Wierońska, Phil Skolnick
Biological psychiatry, 10.1016/j.biopsych.2013.01.021 S0006-3223(13)00092-9
PMID:23453290
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The GABA B receptor agonist CGP44532 and the positive modulator GS39783 reverse some behavioural changes related to positive syndromes of psychosis in mice.
J M Wierońska, M Kusek, K Tokarski, J Wabno, W Froestl, A Pilc
British journal of pharmacology, 10.1111/j.1476-5381.2011.01301.x
PMID:21371011
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Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia.
Joanna M Wierońska, Katarzyna Stachowicz, Francine Acher, Tomasz Lech, Andrzej Pilc
Psychopharmacology, 10.1007/s00213-011-2502-2
PMID:21952670
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On the mechanism of anti-hyperthermic effects of LY379268 and LY487379, group II mGlu receptors activators, in the stress-induced hyperthermia in singly housed mice.
J M Wierońska, K Stachowicz, P Brański, A Pałucha-Poniewiera, A Pilc
Neuropharmacology, 10.1016/j.neuropharm.2011.07.042
PMID:21855555
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Metabotropic glutamate receptor 4 novel agonist LSP1-2111 with anxiolytic, but not antidepressant-like activity, mediated by serotonergic and GABAergic systems.
Joanna M Wierońska, Katarzyna Stachowicz, Agnieszka Pałucha-Poniewiera, Francine Acher, Piotr Brański, Andrzej Pilc
Neuropharmacology, 10.1016/j.neuropharm.2010.08.008
PMID:20713068
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GABAergic dysfunction in mGlu7 receptor-deficient mice as reflected by decreased levels of glutamic acid decarboxylase 65 and 67kDa and increased reelin proteins in the hippocampus.
Joanna M Wierońska, P Brański, A Siwek, M Dybala, G Nowak, A Pilc
Brain research, 10.1016/j.brainres.2010.03.078
PMID:20353761
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Metabotropic glutamate receptors in the tripartite synapse as a target for new psychotropic drugs.
Joanna M Wierońska, Andrzej Pilc
Neurochemistry international, 10.1016/j.neuint.2009.02.019
PMID:19428811
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