Employees - Institute of Pharmacology - Polish Academy of Sciences

Comparative effectiveness of abatacept, apremilast, secukinumab and ustekinumab treatment of psoriatic arthritis: a systematic review and network meta-analysis. P Kawalec, P Holko, P Moćko, A Pilc
Rheumatology international, 10.1007/s00296-017-3919-7
PMID:29285605

The involvement of monoaminergic neurotransmission in the antidepressant-like action of scopolamine in the tail suspension test. Agnieszka Pałucha-Poniewiera, Karolina Podkowa, Tomasz Lenda, Andrzej Pilc
Progress in neuro-psychopharmacology & biological psychiatry, S0278-5846(17)30220-8 10.1016/j.pnpbp.2017.06.022
PMID:28647535

Expression of group III metabotropic glutamate receptors in the reproductive system of male mice. Marcin Marciniak, Barbara Chruscicka, Tomasz Lech, Grzegorz Burnat, Andrzej Pilc
Reproduction, fertility, and development, 10.1071/RD14132
PMID:25066043

Disease activity, quality of life, and indirect costs of ulcerative colitis in Poland. Paweł Kawalec, Ewa Stawowczyk, Małgorzata Mossakowska, Andrzej Pilc
Przeglad gastroenterologiczny, 10.5114/pg.2017.66324
PMID:28337239

Safety Profile of Biologic Drugs in the Treatment of Inflammatory Bowel Diseases: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials. Paweł Moćko, Paweł Kawalec, Andrzej Pilc
Clinical drug investigation, 10.1007/s40261-016-0459-y
PMID:27599485

Serotonin transporter and receptor ligands with antidepressant activity as neuroprotective and proapoptotic agents. Zdzislaw Chilmonczyk, Andrzej J Bojarski, Andrzej Pilc, Ingebrigt Sylte
Pharmacological reports : PR, S1734-1140(16)30162-1 10.1016/j.pharep.2017.01.011
PMID:28324844

Involvement of GABAB Receptor Signaling in Antipsychotic-like Action of the Novel Orthosteric Agonist of the mGlu4 Receptor, LSP4-2022. Monika Woźniak, Francine Acher, Marcin Marciniak, Magdalena Lasoń-Tyburkiewicz, Piotr Gruca, Mariusz Papp, Andrzej Pilc, Joanna M Wierońska
Current neuropharmacology,
PMID:26769224

Health-Related Quality of Life Impairment and Indirect Cost of Crohn's Disease: A Self-Report Study in Poland. Przemysław Holko, Paweł Kawalec, Małgorzata Mossakowska, Andrzej Pilc
PloS one, 10.1371/journal.pone.0168586
PMID:27992531

The transparency of published health technology assessment-based recommendations on pharmaceutical reimbursement in Poland. Tomasz Bochenek, Ewa Kocot, Marcin Rodzinka, Brian Godman, Katarzyna Maciejewska, Susan Kamal, Andrzej Pilc
Expert review of pharmacoeconomics & outcomes research, 10.1080/14737167.2017.1262767
PMID:27882823

The correlation between HTA recommendations and reimbursement status of orphan drugs in Europe. Paweł Kawalec, Anna Sagan, Andrzej Pilc
Orphanet journal of rare diseases, 10.1186/s13023-016-0501-4
PMID:27600717

Antidepressant-like effects of scopolamine in mice are enhanced by the group II mGlu receptor antagonist LY341495. Karolina Podkowa, Adrian Podkowa, Kinga Sałat, Tomasz Lenda, Andrzej Pilc, Agnieszka Pałucha-Poniewiera
Neuropharmacology, S0028-3908(16)30367-7 10.1016/j.neuropharm.2016.08.031
PMID:27569995

Effectiveness and safety of vedolizumab for treatment of Crohn's disease: a systematic review and meta-analysis. Paweł Moćko, Paweł Kawalec, Beata Smela-Lipińska, Andrzej Pilc
Archives of medical science : AMS,
PMID:27695501

Cost-utility analysis of 1-year treatment with adalimumab/standard care and standard care alone for ulcerative colitis in Poland. Ewa Stawowczyk, Paweł Kawalec, Andrzej Pilc
European journal of clinical pharmacology,
PMID:27497991

Cost-Effectiveness Analysis of 1-Year Treatment with Golimumab/Standard Care and Standard Care Alone for Ulcerative Colitis in Poland. Ewa Stawowczyk, Paweł Kawalec, Andrzej Pilc
PloS one, 10.1371/journal.pone.0160444
PMID:27494322

Glutamate-Based Drug Discovery for Novel Antidepressants. Agnieszka Pałucha-Poniewiera, Andrzej Pilc
Expert opinion on drug discovery, 10.1080/17460441.2016.1213234
PMID:27409299

Safety profile of biologic drugs in the therapy of Crohn disease: A systematic review and network meta-analysis. Paweł Moćko, Paweł Kawalec, Andrzej Pilc
Pharmacological reports : PR, S1734-1140(16)30100-1 10.1016/j.pharep.2016.07.013
PMID:27686963

Neurochemical and behavioral studies on the 5-HT1A-dependent antipsychotic action of the mGlu4 receptor agonist LSP4-2022. Monika Woźniak, Krystyna Gołembiowska, Karolina Noworyta-Sokołowska, Francine Acher, Paulina Cieślik, Magdalena Kusek, Krzysztof Tokarski, Andrzej Pilc, Joanna M Wierońska
Neuropharmacology, S0028-3908(16)30278-7 10.1016/j.neuropharm.2016.06.025
PMID:27465045

Safety Profile of Biologic Drugs in the Therapy of Ulcerative Colitis: A Systematic Review and Network Meta-Analysis. Paweł Moćko, Paweł Kawalec, Andrzej Pilc
Pharmacotherapy, 10.1002/phar.1785
PMID:27312826

Vedolizumab Compared with Certolizumab in the Therapy of Crohn Disease: A Systematic Review and Indirect Comparison. Paweł Kawalec, Pawel Moćko, Andrzej Pilc, Maria Radziwon-Zalewska, Iwona Malinowska-Lipień
Pharmacotherapy, 10.1002/phar.1784
PMID:27292108

The usefulness of monitored therapy using Clozapine concentration in the blood serum for determining drug dose in Polish schizophrenic patients. Jadwiga Piwowarska, Maria Radziwoń-Zaleska, Martyna Dmochowska, Ewa Szepietowska, Halina Matsumoto, Grażyna Sygitowicz, Andrzej Pilc, Jacek Łukaszkiewicz
Pharmacological reports : PR, S1734-1140(16)30086-X 10.1016/j.pharep.2016.06.016
PMID:27588387

Disease activity, quality of life and indirect costs of psoriatic arthritis in Poland. Paweł Kawalec, Krzysztof Piotr Malinowski, Andrzej Pilc
Rheumatology international, 10.1007/s00296-016-3514-3
PMID:27339273

Group II mGlu receptor antagonist LY341495 enhances the antidepressant-like effects of ketamine in the forced swim test in rats. Karolina Podkowa, Bartłomiej Pochwat, Piotr Brański, Andrzej Pilc, Agnieszka Pałucha-Poniewiera
Psychopharmacology, 10.1007/s00213-016-4325-7
PMID:27286960

Decreased sensitivity to paroxetine-induced inhibition of peripheral blood mononuclear cell growth in depressed and antidepressant treatment-resistant patients. S Rzezniczek, M Obuchowicz, W Datka, M Siwek, D Dudek, K Kmiotek, K Oved, N Shomron, D Gurwitz, A Pilc
Translational psychiatry, 10.1038/tp.2016.90
PMID:27244236

Cost-Utility Analysis of Infliximab with Standard Care versus Standard Care Alone for Induction and Maintenance Treatment of Patients with Ulcerative Colitis in Poland. Ewa Stawowczyk, Paweł Kawalec, Andrzej Pilc
Pharmacotherapy, 10.1002/phar.1742
PMID:27007213

An indirect comparison of infliximab versus adalimumab or golimumab for active ulcerative colitis. Paweł Kawalec, Andrzej Pilc
Archives of medical science : AMS,
PMID:27695502

Over-the-counter medicine and dietary supplement consumption among academic youth in Poland. Tomasz Bochenek, Brian Godman, Katarzyna Lipowska, Karolina Mikrut, Sandra Zuziak, Magdalena Pedzisz, Aneta Nowak, Andrzej Pilc
Expert review of pharmacoeconomics & outcomes research, 10.1586/14737167.2016.1154790
PMID:26886826

Metabotropic glutamate receptors as targets for new antipsychotic drugs: Historical perspective and critical comparative assessment. Joanna M Wierońska, Stevin H Zorn, Dario Doller, Andrzej Pilc
Pharmacology & therapeutics, S0163-7258(15)00199-0 10.1016/j.pharmthera.2015.10.007
PMID:26549541

Neuroprotective effects of mGluR II and III activators against staurosporine- and doxorubicin-induced cellular injury in SH-SY5Y cells: New evidence for a mechanism involving inhibition of AIF translocation. D Jantas, A Greda, M Leskiewicz, B Grygier, A Pilc, W Lason
Neurochemistry international, 10.1016/j.neuint.2014.12.011 S0197-0186(15)00003-0
PMID:25661514

A novel mGlu4 selective agonist LSP4-2022 increases behavioral despair in mouse models of antidepressant action. Karolina Podkowa, Szymon Rzeźniczek, Marcin Marciniak, Francine Acher, Andrzej Pilc, Agnieszka Pałucha-Poniewiera
Neuropharmacology, 10.1016/j.neuropharm.2015.05.039 S0028-3908(15)00242-7
PMID:26074092

Functional Selectivity and Antidepressant Activity of Serotonin 1A Receptor Ligands. Zdzisław Chilmonczyk, Andrzej Jacek Bojarski, Andrzej Pilc, Ingebrigt Sylte
International journal of molecular sciences, 10.3390/ijms160818474
PMID:26262615

A Qualitative Approach to a Better Understanding of the Problems Underlying Drug Shortages, as Viewed from Belgian, French and the European Union's Perspectives. Petronille Bogaert, Tomasz Bochenek, Anna Prokop, Andrzej Pilc
PloS one, 10.1371/journal.pone.0125691
PMID:25942432

Efavirenz-Based Regimens in Antiretroviral-Naive HIV-Infected Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Joanna Kryst, Paweł Kawalec, Andrzej Pilc
PloS one, 10.1371/journal.pone.0124279
PMID:25933004

mGlu₅-GABAB interplay in animal models of positive, negative and cognitive symptoms of schizophrenia. Joanna M Wierońska, Natalia Kłeczek, Monika Woźniak, Piotr Gruca, Magdalena Łasoń-Tyburkiewicz, Mariusz Papp, Piotr Brański, Grzegorz Burnat, Andrzej Pilc
Neurochemistry international, 10.1016/j.neuint.2015.03.010 S0197-0186(15)00061-3
PMID:25863284

Pregabalin for the treatment of social anxiety disorder. Paweł Kawalec, Agnieszka Cierniak, Andrzej Pilc, Gabriel Nowak
Expert opinion on investigational drugs, 10.1517/13543784.2014.979283
PMID:25361817

Zinc deficiency in rats is associated with up-regulation of hippocampal NMDA receptor. Urszula Doboszewska, Magdalena Sowa-Kućma, Katarzyna Młyniec, Bartłomiej Pochwat, Malgorzata Hołuj, Beata Ostachowicz, Andrzej Pilc, Gabriel Nowak, Bernadeta Szewczyk
Progress in neuro-psychopharmacology & biological psychiatry, 10.1016/j.pnpbp.2014.09.013 S0278-5846(14)00189-4
PMID:25290638

Tetracycline-based system for controlled inducible expression of group III metabotropic glutamate receptors. Barbara Chruścicka, Grzegorz Burnat, Piotr Brański, Paulina Chorobik, Tomasz Lenda, Marcin Marciniak, Andrzej Pilc
Journal of biomolecular screening, 10.1177/1087057114559183
PMID:25394730

Is the mGlu5 receptor a possible target for new antidepressant drugs? Agnieszka Pałucha-Poniewiera, Joanna M Wierońska, Piotr Brański, Grzegorz Burnat, Barbara Chruścicka, Andrzej Pilc
Pharmacological reports : PR,
PMID:24552998

[The role of the cytostatic drugs unit in rationalization of hospital drugs management--the case study and the analysis of drug utilization]. Sandra Zuziak, Roman Topór-Madry, Andrzej Pilc, Tomasz Bochenek
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego,
PMID:25154199

NMDA antagonists under investigation for the treatment of major depressive disorder. Bartłomiej Pochwat, Agnieszka Pałucha-Poniewiera, Bernadeta Szewczyk, Andrzej Pilc, Gabriel Nowak
Expert opinion on investigational drugs, 10.1517/13543784.2014.918951
PMID:24818801

The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT1A receptor signaling: mechanistic studies. Joanna M Wierońska, Anna Sławińska, Magdalena Łasoń-Tyburkiewicz, Piotr Gruca, Mariusz Papp, Stevin H Zorn, Darío Doller, Natalia Kłeczek, Karolina Noworyta-Sokołowska, Krystyna Gołembiowska, Andrzej Pilc
Psychopharmacology, 10.1007/s00213-014-3657-4
PMID:25012236

Are pharmacological properties of anticoagulants reflected in pharmaceutical pricing and reimbursement policy? Out-patient treatment of venous thromboembolism and utilization of anticoagulants in Poland. T Bochenek, M Czarnogorski, R Nizankowski, A Pilc
European review for medical and pharmacological sciences, 7474
PMID:24943977

Prolonged administration of antidepressant drugs leads to increased binding of [(3)H]MPEP to mGlu5 receptors. Gabriel Nowak, Lucyna Pomierny-Chamioło, Agata Siwek, Ewa Niedzielska, Bartosz Pomierny, Agnieszka Pałucha-Poniewiera, Andrzej Pilc
Neuropharmacology, 10.1016/j.neuropharm.2014.04.016 S0028-3908(14)00152-X
PMID:24796254

Inhibitory actions of mGlu4 receptor ligands on cocaine-, but not nicotine-, induced sensitizing and conditioning locomotor responses in rats. Magdalena Zaniewska, Edmund Przegaliński, Małgorzata Filip, Andrzej Pilc, Darío Doller
Pharmacological reports : PR, 10.1016/j.pharep.2013.12.001 S1734-1140(14)00035-8
PMID:24911071

Neuroprotective effects of metabotropic glutamate receptor group II and III activators against MPP(+)-induced cell death in human neuroblastoma SH-SY5Y cells: the impact of cell differentiation state. D Jantas, A Greda, S Golda, M Korostynski, B Grygier, A Roman, A Pilc, W Lason
Neuropharmacology, 10.1016/j.neuropharm.2014.03.019 S0028-3908(14)00124-5
PMID:24713472

Lu AF21934, a positive allosteric modulator of mGlu4 receptors, reduces the harmaline-induced hyperactivity but not tremor in rats. Krystyna Ossowska, Jadwiga Wardas, Klemencja Berghauzen-Maciejewska, Urszula Głowacka, Katarzyna Kuter, Andrzej Pilc, Stevin H Zorn, Dario Doller
Neuropharmacology, 10.1016/j.neuropharm.2014.03.018 S0028-3908(14)00123-3
PMID:24726309

The effectiveness of dimethyl fumarate monotherapy in the treatment of relapsing-remitting multiple sclerosis: a systematic review and meta-analysis. Paweł Kawalec, Alicja Mikrut, Natalia Wiśniewska, Andrzej Pilc
Current neuropharmacology, 10.2174/1570159X12666140115214801
PMID:24851089

Activation of the mTOR signaling pathway in the antidepressant-like activity of the mGlu5 antagonist MTEP and the mGlu7 agonist AMN082 in the FST in rats. Agnieszka Pałucha-Poniewiera, Bernadeta Szewczyk, Andrzej Pilc
Neuropharmacology, 10.1016/j.neuropharm.2014.03.001 S0028-3908(14)00085-9
PMID:24631968

Oxidative stress markers in affective disorders. Marcin Siwek, Magdalena Sowa-Kućma, Dominika Dudek, Krzysztof Styczeń, Bernadeta Szewczyk, Katarzyna Kotarska, Paulina Misztakk, Agnieszka Pilc, Małgorzata Wolak, Gabriel Nowak
Pharmacological reports : PR,
PMID:24553004

The antidepressant-like action of mGlu5 receptor antagonist, MTEP, in the tail suspension test in mice is serotonin dependent. Agnieszka Pałucha-Poniewiera, Piotr Brański, Joanna M Wierońska, Katarzyna Stachowicz, Anna Sławińska, Andrzej Pilc
Psychopharmacology,
PMID:23958941

The antipsychotic-like effects of positive allosteric modulators of metabotropic glutamate mGlu4 receptors in rodents. Anna Sławińska, Joanna M Wierońska, Katarzyna Stachowicz, Marcin Marciniak, Magdalena Lasoń-Tyburkiewicz, Piotr Gruca, Mariusz Papp, Magdalena Kusek, Krzysztof Tokarski, Darío Doller, Andrzej Pilc
British journal of pharmacology, 10.1111/bph.12254
PMID:23714045

Tumor necrosis factor-α antibodies (infliximab, adalimumab and certolizumab) in Crohn's disease: systematic review and meta-analysis. Paweł Kawalec, Alicja Mikrut, Natalia Wiśniewska, Andrzej Pilc
Archives of medical science : AMS, 10.5114/aoms.2013.38670
PMID:24273556

Zinc, magnesium and NMDA receptor alterations in the hippocampus of suicide victims. Magdalena Sowa-Kućma, Bernadeta Szewczyk, Krystyna Sadlik, Wojciech Piekoszewski, Franciszek Trela, Włodzimierz Opoka, Ewa Poleszak, Andrzej Pilc, Gabriel Nowak
Journal of affective disorders, 10.1016/j.jad.2013.08.009 S0165-0327(13)00626-5
PMID:24055117

Involvement of NMDA and AMPA receptors in the antidepressant-like activity of antidepressant drugs in the forced swim test. Małgorzata Wolak, Agata Siwek, Bernadeta Szewczyk, Ewa Poleszak, Andrzej Pilc, Piotr Popik, Gabriel Nowak
Pharmacological reports : PR,
PMID:24145093

Nevirapine-based regimens in HIV-infected antiretroviral-naive patients: systematic review and meta-analysis of randomized controlled trials. Paweł Kawalec, Joanna Kryst, Alicja Mikrut, Andrzej Pilc
PloS one, 10.1371/journal.pone.0076587
PMID:24116123

[Clinical efficacy and safety of prolonged use of the valganciclovir for the treatment of cytomegalovirus disease in patients after kidney transplantation]. Paweł Kawalec, Monika Szkultecka-Debek, Justyna Maks, Anna Paszulewicz, Aneta Kaweczyńska-Lasoń, Andrzej Pilc
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego,
PMID:23984598

Zinc deficiency alters responsiveness to antidepressant drugs in mice. Katarzyna Młyniec, Bogusława Budziszewska, Witold Reczyński, Urszula Doboszewska, Andrzej Pilc, Gabriel Nowak
Pharmacological reports : PR,
PMID:23950580

The reversal of cognitive, but not negative or positive symptoms of schizophrenia, by the mGlu₂/₃ receptor agonist, LY379268, is 5-HT₁A dependent. Joanna M Wierońska, A Sławińska, K Stachowicz, M Łasoń-Tyburkiewicz, P Gruca, M Papp, A Pilc
Behavioural brain research, 10.1016/j.bbr.2013.08.007 S0166-4328(13)00483-X
PMID:23948211

The effectiveness of tofacitinib, a novel Janus kinase inhibitor, in the treatment of rheumatoid arthritis: a systematic review and meta-analysis. Paweł Kawalec, Alicja Mikrut, Natalia Wiśniewska, Andrzej Pilc
Clinical rheumatology, 10.1007/s10067-013-2329-9
PMID:23877486

Glutamate-based anxiolytic ligands in clinical trials. Joanna M Wierońska, Andrzej Pilc
Expert opinion on investigational drugs, 10.1517/13543784.2013.803066
PMID:23718208

The antipsychotic-like effects of the mGlu group III orthosteric agonist, LSP1-2111, involves 5-HT₁A signalling. Joanna M Wierońska, Francine C Acher, Anna Sławińska, Piotr Gruca, Magdalena Lasoń-Tyburkiewicz, Mariusz Papp, Andrzej Pilc
Psychopharmacology, 10.1007/s00213-013-3005-0
PMID:23474845

Glutamate-based antidepressants: preclinical psychopharmacology. Andrzej Pilc, Joanna M Wierońska, Phil Skolnick
Biological psychiatry, 10.1016/j.biopsych.2013.01.021 S0006-3223(13)00092-9
PMID:23453290

Time course of zinc deprivation-induced alterations of mice behavior in the forced swim test. Katarzyna Młyniec, Claire Linzi Davies, Bogusława Budziszewska, Włodzimierz Opoka, Witold Reczyński, Magdalena Sowa-Kućma, Urszula Doboszewska, Andrzej Pilc, Gabriel Nowak
Pharmacological reports : PR,
PMID:22814010

Different pattern of changes in calcium binding proteins immunoreactivity in the medial prefrontal cortex of rats exposed to stress models of depression. Monika Zadrożna, Barbara Nowak, Magdalena Łasoń-Tyburkiewicz, Małgorzata Wolak, Magdalena Sowa-Kućma, Mariusz Papp, Grażyna Ossowska, Andrzej Pilc, Gabriel Nowak
Pharmacological reports : PR,
PMID:22358102

A selective mGlu7 receptor antagonist MMPIP reversed antidepressant-like effects of AMN082 in rats. Agnieszka Pałucha-Poniewiera, Andrzej Pilc
Behavioural brain research, 10.1016/j.bbr.2012.10.004 S0166-4328(12)00643-2
PMID:23085340

Sipuleucel-T immunotherapy for castration-resistant prostate cancer. A systematic review and meta-analysis. Paweł Kawalec, Anna Paszulewicz, Przemysław Holko, Andrzej Pilc
Archives of medical science : AMS, 10.5114/aoms.2012.31610
PMID:23185184

Simultaneous alterations of brain and plasma serotonin concentrations and liver cytochrome P450 in rats fed on a tryptophan-free diet. Marta Kot, Andrzej Pilc, Władysława A Daniel
Pharmacological research, 10.1016/j.phrs.2012.06.009
PMID:22749902

Involvement of mGlu5 and NMDA receptors in the antidepressant-like effect of acamprosate in the tail suspension test. Agnieszka Pałucha-Poniewiera, Andrzej Pilc
Progress in neuro-psychopharmacology & biological psychiatry, 10.1016/j.pnpbp.2012.05.015
PMID:22651960

mGlu2/3 and mGlu5 receptors: potential targets for novel antidepressants. Shigeyuki Chaki, Yukio Ago, Agnieszka Palucha-Paniewiera, Francesco Matrisciano, Andrzej Pilc
Neuropharmacology, 10.1016/j.neuropharm.2012.05.022 S0028-3908(12)00220-1
PMID:22640631

Anxiolytic- but not antidepressant-like activity of Lu AF21934, a novel, selective positive allosteric modulator of the mGlu₄ receptor. Anna Sławińska, Joanna M Wierońska, Katarzyna Stachowicz, Agnieszka Pałucha-Poniewiera, Michelle A Uberti, Maria A Bacolod, Dario Doller, Andrzej Pilc
Neuropharmacology, 10.1016/j.neuropharm.2012.05.001 S0028-3908(12)00174-8
PMID:22634361

Anxiolytic-like activity of MGS0039, a selective group II mGlu receptor antagonist, is serotonin- and GABA-dependent. Katarzyna Stachowicz, Joanna Wierońska, Helena Domin, Shigeyuki Chaki, Andrzej Pilc
Pharmacological reports : PR,
PMID:22001975

Anxiolytic-like activity of zinc in rodent tests. Anna Partyka, Magdalena Jastrzębska-Więsek, Bernadeta Szewczyk, Katarzyna Stachowicz, Anna Sławińska, Ewa Poleszak, Urszula Doboszewska, Andrzej Pilc, Gabriel Nowak
Pharmacological reports : PR,
PMID:22001993

Investigational NMDA receptor modulators for depression. Bernadeta Szewczyk, Agnieszka Pałucha-Poniewiera, Ewa Poleszak, Andrzej Pilc, Gabriel Nowak
Expert opinion on investigational drugs, 10.1517/13543784.2012.638916
PMID:22097925

The GABA B receptor agonist CGP44532 and the positive modulator GS39783 reverse some behavioural changes related to positive syndromes of psychosis in mice. J M Wierońska, M Kusek, K Tokarski, J Wabno, W Froestl, A Pilc
British journal of pharmacology, 10.1111/j.1476-5381.2011.01301.x
PMID:21371011

Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia. Joanna M Wierońska, Katarzyna Stachowicz, Francine Acher, Tomasz Lech, Andrzej Pilc
Psychopharmacology, 10.1007/s00213-011-2502-2
PMID:21952670

NMDA but not AMPA glutamatergic receptors are involved in the antidepressant-like activity of MTEP during the forced swim test in mice. Lucyna Pomierny-Chamioło, Ewa Poleszak, Andrzej Pilc, Gabriel Nowak
Pharmacological reports : PR,
PMID:21273676

Alterations in hippocampal calcium-binding neurons induced by stress models of depression: a preliminary assessment. Barbara Nowak, Monika Zadrożna, Grażyna Ossowska, Magdalena Sowa-Kućma, Piotr Gruca, Mariusz Papp, Małgorzata Dybała, Andrzej Pilc, Gabriel Nowak
Pharmacological reports : PR,
PMID:21273679

On the mechanism of anti-hyperthermic effects of LY379268 and LY487379, group II mGlu receptors activators, in the stress-induced hyperthermia in singly housed mice. J M Wierońska, K Stachowicz, P Brański, A Pałucha-Poniewiera, A Pilc
Neuropharmacology, 10.1016/j.neuropharm.2011.07.042
PMID:21855555

The effect of physical activity on the brain derived neurotrophic factor: from animal to human studies. J A Zoladz, A Pilc
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society,
PMID:21081796

Metabotropic glutamate receptor 4 novel agonist LSP1-2111 with anxiolytic, but not antidepressant-like activity, mediated by serotonergic and GABAergic systems. Joanna M Wierońska, Katarzyna Stachowicz, Agnieszka Pałucha-Poniewiera, Francine Acher, Piotr Brański, Andrzej Pilc
Neuropharmacology, 10.1016/j.neuropharm.2010.08.008
PMID:20713068

On the mechanism of the antidepressant-like action of group II mGlu receptor antagonist, MGS0039. Agnieszka Pałucha-Poniewiera, Joanna M Wierońska, Piotr Brański, Katarzyna Stachowicz, Shigeyuki Chaki, Andrzej Pilc
Psychopharmacology, 10.1007/s00213-010-1978-5
PMID:20703449

The antidepressant-like action of metabotropic glutamate 7 receptor agonist N,N'-bis(diphenylmethyl)-1,2-ethanediamine (AMN082) is serotonin-dependent. Agnieszka Pałucha-Poniewiera, Piotr Brański, Tomasz Lenda, Andrzej Pilc
The Journal of pharmacology and experimental therapeutics, 10.1124/jpet.110.169730
PMID:20562216

Chronic treatment with zinc and antidepressants induces enhancement of presynaptic/extracellular zinc concentration in the rat prefrontal cortex. Magdalena Sowa-Kućma, Magdalena Kowalska, Marek Szlósarczyk, Krystyna Gołembiowska, Włodzimierz Opoka, Bogusław Baś, Andrzej Pilc, Gabriel Nowak
Amino acids, 10.1007/s00726-010-0641-0
PMID:20532950

Serum zinc level in depressed patients during zinc supplementation of imipramine treatment. Marcin Siwek, Dominika Dudek, Małgorzata Schlegel-Zawadzka, Agnieszka Morawska, Wojciech Piekoszewski, Włodzimierz Opoka, Andrzej Zieba, Andrzej Pilc, Piotr Popik, Gabriel Nowak
Journal of affective disorders, 10.1016/j.jad.2010.04.024
PMID:20493532

Zinc-induced adaptive changes in NMDA/glutamatergic and serotonergic receptors. Agnieszka Cichy, Magdalena Sowa-Kućma, Beata Legutko, Lucyna Pomierny-Chamioło, Agata Siwek, Anna Piotrowska, Bernadeta Szewczyk, Ewa Poleszak, Andrzej Pilc, Gabriel Nowak
Pharmacological reports : PR,
PMID:20081255

GABAergic dysfunction in mGlu7 receptor-deficient mice as reflected by decreased levels of glutamic acid decarboxylase 65 and 67kDa and increased reelin proteins in the hippocampus. Joanna M Wierońska, P Brański, A Siwek, M Dybala, G Nowak, A Pilc
Brain research, 10.1016/j.brainres.2010.03.078
PMID:20353761

The involvement of NMDA and AMPA receptors in the mechanism of antidepressant-like action of zinc in the forced swim test. B Szewczyk, E Poleszak, M Sowa-Kućma, A Wróbel, S Słotwiński, J Listos, P Wlaź, A Cichy, A Siwek, M Dybała, K Gołembiowska, A Pilc, Gabriel Nowak
Amino acids, 10.1007/s00726-009-0412-y
PMID:19956994

Group III mGlu receptor agonist, ACPT-I, attenuates morphine-withdrawal symptoms after peripheral administration in mice. Agnieszka Pałucha-Poniewiera, Kinga Novák, Andrzej Pilc
Progress in neuro-psychopharmacology & biological psychiatry, 10.1016/j.pnpbp.2009.07.029
PMID:19660510

The group III mGlu receptor agonist ACPT-I exerts anxiolytic-like but not antidepressant-like effects, mediated by the serotonergic and GABA-ergic systems. K Stachowicz, A Kłodzińska, A Palucha-Poniewiera, S Schann, P Neuville, A Pilc
Neuropharmacology, 10.1016/j.neuropharm.2009.06.005
PMID:19539634

Olfactory bulbectomy and amitriptyline treatment influences mGlu receptors expression in the mouse brain hippocampus. Joanna M Wierońska, Beata Legutko, Dorota Dudys, Andrzej Pilc
Pharmacological reports : PR,
PMID:19211976

D-serine, a selective glycine/N-methyl-D-aspartate receptor agonist, antagonizes the antidepressant-like effects of magnesium and zinc in mice. Ewa Poleszak, Bernadeta Szewczyk, Aleksandra Wlaź, Sylwia Fidecka, Piotr Wlaź, Andrzej Pilc, Gabriel Nowak
Pharmacological reports : PR,
PMID:19211995

Endurance training increases plasma brain-derived neurotrophic factor concentration in young healthy men. J A Zoladz, A Pilc, J Majerczak, M Grandys, J Zapart-Bukowska, K Duda
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society,
PMID:19258661

Zinc supplementation augments efficacy of imipramine in treatment resistant patients: a double blind, placebo-controlled study. Marcin Siwek, Dominika Dudek, Ian A Paul, Magdalena Sowa-Kućma, Andrzej Zieba, Piotr Popik, Andrzej Pilc, Gabriel Nowak
Journal of affective disorders, 10.1016/j.jad.2009.02.014
PMID:19278731

Metabotropic glutamate receptors in the tripartite synapse as a target for new psychotropic drugs. Joanna M Wierońska, Andrzej Pilc
Neurochemistry international, 10.1016/j.neuint.2009.02.019
PMID:19428811

Antidepressant activity of zinc and magnesium in view of the current hypotheses of antidepressant action. Bernadeta Szewczyk, Ewa Poleszak, Magdalena Sowa-Kućma, Marcin Siwek, Dominika Dudek, Beata Ryszewska-Pokraśniewicz, Maria Radziwoń-Zaleska, Włodzimierz Opoka, Janusz Czekaj, Andrzej Pilc, Gabriel Nowak
Pharmacological reports : PR,
PMID:19066406

The involvement of serotonergic system in the antidepressant effect of zinc in the forced swim test. Bernadeta Szewczyk, Ewa Poleszak, Piotr Wlaź, Andrzej Wróbel, Eliza Blicharska, Agnieszka Cichy, Małgorzata Dybała, Agata Siwek, Lucyna Pomierny-Chamioło, Anna Piotrowska, Piotr Brański, Andrzej Pilc, Gabriel Nowak
Progress in neuro-psychopharmacology & biological psychiatry, 10.1016/j.pnpbp.2008.12.011
PMID:19150479

The use of citation indicators to identify and support high-quality research in Poland. Andrzej Pilc
Archivum immunologiae et therapiae experimentalis, 10.1007/s00005-008-0042-1
PMID:19043671

Activation of the NMDA/glutamate receptor complex antagonizes the NMDA antagonist-induced antidepressant-like effects in the forced swim test. Ewa Poleszak, Piotr Wlaź, Andrzej Wróbel, Małgorzata Dybała, Magdalena Sowa, Sylwia Fidecka, Andrzej Pilc, Gabriel Nowak
Pharmacological reports : PR,
PMID:18048961

Lack of NMDA-AMPA interaction in antidepressant-like effect of CGP 37849, an antagonist of NMDA receptor, in the forced swim test. Małgorzata Dybała, Agata Siwek, Ewa Poleszak, Andrzej Pilc, Gabriel Nowak
Journal of neural transmission (Vienna, Austria : 1996), 10.1007/s00702-008-0128-2
PMID:18839056

Effects of GABAB receptor ligands in rodent tests of anxiety-like behavior. Anna Partyka, Aleksandra Kłodzińska, Bernadeta Szewczyk, Joanna M Wierońska, Ewa Chojnacka-Wójcik, Tadeusz Librowski, Barbara Filipek, Gabriel Nowak, Andrzej Pilc
Pharmacological reports : PR,
PMID:18195467

Effects of South African traditional medicine in animal models for depression. Mikael E Pedersen, Bernadeta Szewczyk, Katarzyna Stachowicz, Joanna Wieronska, Jacob Andersen, Gary I Stafford, Johannes van Staden, Andrzej Pilc, Anna K Jäger
Journal of ethnopharmacology, 10.1016/j.jep.2008.08.030
PMID:18809486

Antidepressant-like activity of zinc: further behavioral and molecular evidence. Magdalena Sowa-Kućma, Beata Legutko, Bernadeta Szewczyk, Kinga Novak, Paweł Znojek, Ewa Poleszak, Mariusz Papp, Andrzej Pilc, Gabriel Nowak
Journal of neural transmission (Vienna, Austria : 1996), 10.1007/s00702-008-0115-7
PMID:18766297

Peripheral administration of group III mGlu receptor agonist ACPT-I exerts potential antipsychotic effects in rodents. A Pałucha-Poniewiera, A Kłodzińska, K Stachowicz, K Tokarski, G Hess, S Schann, M Frauli, P Neuville, A Pilc
Neuropharmacology, 10.1016/j.neuropharm.2008.06.033
PMID:18619473

Antidepressant-like activity of 8-Br-cAMP, a PKA activator, in the forced swim test. Piotr Brański, Agnieszka Palucha, Bernadeta Szewczyk, Joanna M Wierońska, Andrzej Pilc, Gabriel Nowak
Journal of neural transmission (Vienna, Austria : 1996), 10.1007/s00702-008-0023-x
PMID:18239846

Citalopram influences mGlu7, but not mGlu4 receptors' expression in the rat brain hippocampus and cortex. Joanna M Wierońska, Kinga Kłak, Agnieszka Pałucha, Piotr Brański, Andrzej Pilc
Brain research,
PMID:17976546

Mood disorders: regulation by metabotropic glutamate receptors. Andrzej Pilc, Shigeyuki Chaki, Gabriel Nowak, Jeffrey M Witkin
Biochemical pharmacology, 10.1016/j.bcp.2007.09.021
PMID:18164691

Anxiolytic-like action of MTEP expressed in the conflict drinking Vogel test in rats is serotonin dependent. K Stachowicz, K Gołembiowska, M Sowa, G Nowak, E Chojnacka-Wójcik, A Pilc
Neuropharmacology,
PMID:17870136

NMDA/glutamate mechanism of antidepressant-like action of magnesium in forced swim test in mice. Ewa Poleszak, Piotr Wlaź, Ewa Kedzierska, Dorota Nieoczym, Andrzej Wróbel, Sylwia Fidecka, Andrzej Pilc, Gabriel Nowak
Pharmacology, biochemistry, and behavior,
PMID:17825400

Activation of the mGlu7 receptor elicits antidepressant-like effects in mice. Agnieszka Palucha, Kinga Klak, Piotr Branski, Herman van der Putten, Peter J Flor, Andrzej Pilc
Psychopharmacology,
PMID:17622518

Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs. Agnieszka Palucha, Andrzej Pilc
Pharmacology & therapeutics,
PMID:17582504

Anxiolytic-like effects of group III mGlu receptor ligands in the hippocampus involve GABAA signaling. Katarzyna Stachowicz, Ewa Chojnacka-Wójcik, Kinga Kłak, Andrzej Pilc
Pharmacological reports : PR,
PMID:17220539

Metabotropic glutamate receptors. A Pilc, K Ossowska
Amino acids,
PMID:17245617

The influence of group III metabotropic glutamate receptor stimulation by (1S,3R,4S)-1-aminocyclo-pentane-1,3,4-tricarboxylic acid on the parkinsonian-like akinesia and striatal proenkephalin and prodynorphin mRNA expression in rats. J Konieczny, J Wardas, K Kuter, A Pilc, K Ossowska
Neuroscience,
PMID:17224239

Effect of MPEP treatment on brain-derived neurotrophic factor gene expression. Beata Legutko, Bernadeta Szewczyk, Lucyna Pomierny-Chamioło, Gabriel Nowak, Andrzej Pilc
Pharmacological reports : PR,
PMID:16845218

MPEP, mGlu5 receptor antagonist, regulates NPYmRNA expression in hippocampal and amygdalar neurons. Maria Smiałowska, Joanna M Wierońska, Piotr Brański, Ewa Obuchowicz, Andrzej Pilc
Polish journal of pharmacology,
PMID:15662083

Selective mGlu5 receptor antagonist MTEP attenuates naloxone-induced morphine withdrawal symptoms. Agnieszka Pałucha, Piotr Brański, Andrzej Pilc
Polish journal of pharmacology,
PMID:15662102

Intraamygdaloid administration of BIBO 3304 increases water intake and extends anxiolytic effects. Joanna M Wierońska, Katarzyna Stachowicz, Aleksandra Kłodzińska, Maria Smiałowska, Andrzej Pilc
Polish journal of pharmacology,
PMID:15662103

Anxiolytic-like effect of group III mGlu receptor antagonist is serotonin-dependent. K Stachowicz, E Chojnacka-Wójcik, K Kłak, A Pilc
Neuropharmacology,
PMID:17020774

Antidepressant-like activity of CGP 36742 and CGP 51176, selective GABAB receptor antagonists, in rodents. G Nowak, A Partyka, A Pałucha, B Szewczyk, J M Wierońska, M Dybała, M Metz, T Librowski, W Froestl, M Papp, A Pilc
British journal of pharmacology,
PMID:16921399

Combined administration of PHCCC, a positive allosteric modulator of mGlu4 receptors and ACPT-I, mGlu III receptor agonist evokes antidepressant-like effects in rats. K Kłak, A Pałucha, P Brański, M Sowa, A Pilc
Amino acids,
PMID:16868652

Zinc and depression. An update. Gabriel Nowak, Bernadeta Szewczyk, Andrzej Pilc
Pharmacological reports : PR,
PMID:16382189

Lack of the antianxiety-like effect of (S)-3,4-DCPG, an mGlu8 receptor agonist, after central administration in rats. Katarzyna Stachowicz, Kinga Kłak, Andrzej Pilc, Ewa Chojnacka-Wójcik
Pharmacological reports : PR,
PMID:16382208

Application of magnetic resonance diffusion anisotropy imaging for the assessment neuroprotecting effects of MPEP, a selective mGluR5 antagonist, on the rat spinal cord injury in vivo. Tomasz Banasik, Andrzej Jasiński, Andrzej Pilc, Katarzyna Majcher, Paweł Brzegowy
Pharmacological reports : PR,
PMID:16382209

Effects of acute and chronic treatment with magnesium in the forced swim test in rats. Ewa Poleszak, Piotr Wlaź, Ewa Kedzierska, Maria Radziwon-Zaleska, Andrzej Pilc, Sylwia Fidecka, Gabriel Nowak
Pharmacological reports : PR,
PMID:16227649

An influence of ligands of metabotropic glutamate receptor subtypes on parkinsonian-like symptoms and the striatopallidal pathway in rats. K Ossowska, J Konieczny, J Wardas, M Pietraszek, K Kuter, S Wolfarth, A Pilc
Amino acids,
PMID:16699817

Increase in synaptic hippocampal zinc concentration following chronic but not acute zinc treatment in rats. Bernadeta Szewczyk, Magdalena Sowa, Artur Czupryn, Joanna M Wierońska, Piotr Brański, Krystyna Sadlik, Włodzimierz Opoka, Wojciech Piekoszewski, Maria Smiałowska, Jolanta Skangiel-Kramska, Andrzej Pilc, Gabriel Nowak
Brain research,
PMID:16674928

GABAergic hypotheses of anxiety and depression: focus on GABA-B receptors. Andrzej Pilc, Gabriel Nowak
Drugs of today (Barcelona, Spain : 1998),
PMID:16395415

MTEP, a new selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5), produces antiparkinsonian-like effects in rats. K Ossowska, J Konieczny, S Wolfarth, A Pilc
Neuropharmacology,
PMID:15919101

Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist. Agnieszka Pałucha, Piotr Brański, Bernadeta Szewczyk, Joanna M Wierońska, Kinga Kłak, Andrzej Pilc
Pharmacology, biochemistry, and behavior,
PMID:16040106

The involvement of glutamate in the pathophysiology of depression. A Palucha, A Pilc
Drug news & perspectives,
PMID:16034483

Enhancement of antidepressant-like activity by joint administration of imipramine and magnesium in the forced swim test: Behavioral and pharmacokinetic studies in mice. Ewa Poleszak, Piotr Wlaź, Bernadeta Szewczyk, Ewa Kedzierska, Elzbieta Wyska, Tadeusz Librowski, Joanna Szymura-Oleksiak, Sylwia Fidecka, Andrzej Pilc, Gabriel Nowak
Pharmacology, biochemistry, and behavior,
PMID:15936065

Anxiolytic-like effects of PHCCC, an allosteric modulator of mGlu4 receptors, in rats. Katarzyna Stachowicz, Kinga Kłak, Aleksandra Kłodzińska, Ewa Chojnacka-Wojcik, Andrzej Pilc
European journal of pharmacology,
PMID:15363989

Zinc treatment induces cortical brain-derived neurotrophic factor gene expression. Gabriel Nowak, Beata Legutko, Bernadeta Szewczyk, Mariusz Papp, Marek Sanak, Andrzej Pilc
European journal of pharmacology,
PMID:15145706

Antidepressant- and anxiolytic-like activity of magnesium in mice. Ewa Poleszak, Bernadeta Szewczyk, Ewa Kedzierska, Piotr Wlaź, Andrzej Pilc, Gabriel Nowak
Pharmacology, biochemistry, and behavior,
PMID:15159129

Anxiolytic-like effects of MTEP, a potent and selective mGlu5 receptor agonist does not involve GABA(A) signaling. Aleksandra Klodzinska, Ewa Tatarczyńska, Ewa Chojnacka-Wójcik, Gabriel Nowak, Nicholas D P Cosford, Andrzej Pilc
Neuropharmacology,
PMID:15275823

Effect of zinc supplementation on antidepressant therapy in unipolar depression: a preliminary placebo-controlled study. Gabriel Nowak, Marcin Siwek, Dominika Dudek, Andrzej Zieba, Andrzej Pilc
Polish journal of pharmacology,
PMID:14730113

Group III mGlu receptor agonists produce anxiolytic- and antidepressant-like effects after central administration in rats. A Pałucha, E Tatarczyńska, P Brański, B Szewczyk, J M Wierońska, K Kłak, E Chojnacka-Wójcik, G Nowak, A Pilc
Neuropharmacology,
PMID:14680755

In the amygdala anxiolytic action of mGlu5 receptors antagonist MPEP involves neuropeptide Y but not GABAA signaling. Joanna M Wierońska, Maria Smiałowska, Piotr Brański, Fabrizio Gasparini, Aleksandra Kłodzińska, Bernadeta Szewczyk, Agnieszka Pałucha, Ewa Chojnacka-Wójcik, Andrzej Pilc
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
PMID:14666119

The role of striatal metabotropic glutamate receptors in Parkinson's disease. K Ossowska, J Konieczny, J Wardas, K Gołembiowska, S Wolfarth, A Pilc
Amino acids,
PMID:12373537

In vitro and in vivo characterization of MPEP, an allosteric modulator of the metabotropic glutamate receptor subtype 5: review article. R Kuhn, A Pagano, N Stoehr, I Vranesic, P J Flor, K Lingenhöhl, W Spooren, C Gentsch, A Vassout, A Pilc, F Gasparini
Amino acids,
PMID:12373539

Antidepressant-like effect of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist in the olfactory bulbectomized rats. J M Wieronska, B Szewczyk, P Branski, A Palucha, A Pilc
Amino acids,
PMID:12373540

Reduced potency of zinc to interact with NMDA receptors in hippocampal tissue of suicide victims. Gabriel Nowak, Bernadeta Szewczyk, Kystyna Sadlik, Wojciech Piekoszewski, Franciszek Trela, Ewa Florek, Andrzej Pilc
Polish journal of pharmacology,
PMID:14506326

Antidepressant-like effects of acute and chronic treatment with zinc in forced swim test and olfactory bulbectomy model in rats. Gabriel Nowak, Bernadeta Szewczyk, Joanna M Wieronska, Piotr Branski, Agnieszka Palucha, Andrzej Pilc, Krystyna Sadlik, Wojciech Piekoszewski
Brain research bulletin,
PMID:12832002

LY-354740 (Eli Lilly). Andrzej Pilc
IDrugs : the investigational drugs journal,
PMID:12789623

On the role of metabotropic glutamate receptors in the mechanisms of action of antidepressants. Agnieszka Pałucha, Andrzej Pilc
Polish journal of pharmacology,
PMID:12866712

Interaction of zinc with antidepressants in the forced swimming test in mice. Bernadeta Szewczyk, Piotr Brański, Joanna M Wierońska, Agnieszka Pałucha, Andrzej Pilc, Gabriel Nowak
Polish journal of pharmacology,
PMID:12866724

Anxiolytic- and antidepressant-like effects of group III metabotropic glutamate agonist (1S,3R,4S)-1-aminocyclopentane-1,3,4-tricarboxylic acid (ACPT-I) in rats. Ewa Tatarczyńska, Agnieszka Pałucha, Bernadeta Szewczyk, Ewa Chojnacka-Wójcik, Joanna Wierońska, Andrzej Pilc
Polish journal of pharmacology,
PMID:12866729

Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats. A Pilc, A Kłodzińska, P Brański, G Nowak, A Pałucha, B Szewczyk, E Tatarczyńska, E Chojnacka-Wójcik, J M Wierońska
Neuropharmacology,
PMID:12213272

Group II mGlu receptor agonists inhibit behavioural and electrophysiological effects of DOI in mice. Aleksandra Kłodzinska, Maria Bijak, Krzysztof Tokarski, Andrzej Pilc
Pharmacology, biochemistry, and behavior,
PMID:12117586

The striatum as a target for anti-rigor effects of an antagonist of mGluR1, but not an agonist of group II metabotropic glutamate receptors. Krystyna Ossowska, Jolanta Konieczny, Andrzej Pilc, Stanislaw Wolfarth
Brain research,
PMID:12231232

Inhibitory effects of MPEP, an mGluR5 antagonist, and memantine, an N-methyl-D-aspartate receptor antagonist, on morphine antinociceptive tolerance in mice. Ewa Kozela, Andrzej Pilc, Piotr Popik
Psychopharmacology,
PMID:12442203

Effect of chronic imipramine or electroconvulsive shock on the expression of mGluR1a and mGluR5a immunoreactivity in rat brain hippocampus. M Smiałowska, B Szewczyk, P Brański, J M Wierońska, A Pałucha, M Bajkowska, A Pilc
Neuropharmacology,
PMID:12128002

Glutamate receptor ligands as anxiolytics. E Chojnacka-Wójcik, A Kłodzinska, A Pilc
Current opinion in investigational drugs (London, England : 2000),
PMID:11892923

Changes in the expression of metabotropic glutamate receptor 5 (mGluR5) in the rat hippocampus in an animal model of depression. J M Wierońska, P Brański, B Szewczyk, A Pałucha, M Papp, P Gruca, E Moryl, A Pilc
Polish journal of pharmacology,
PMID:11985342

Developmental changes in the modulation of cyclic amp accumulation by activation of metabotropic glutamate receptors. A Pałucha, P Brański, B Kroczka, J Wierońska, A Pilc
Polish journal of pharmacology,
PMID:11990066

Effects of anxiolytic drugs on some behavioral consequences in olfactory bulbectomized rats. J M Wierońska, M Papp, A Pilc
Polish journal of pharmacology,
PMID:11990071

The antianxiety-like effects of antagonists of group I and agonists of group II and III metabotropic glutamate receptors after intrahippocampal administration. E Tatarczyńska, A Kłodzińska, B Kroczka, E Chojnacka-Wójcik, A Pilc
Psychopharmacology,
PMID:11685389

Blockade of the metabotropic glutamate receptor subtype 5 (mGluR5) produces antiparkinsonian-like effects in rats. K Ossowska, J Konieczny, S Wolfarth, J Wierońska, A Pilc
Neuropharmacology,
PMID:11543761

[Zinc homeostasis and glutamatergic system in the pathogenesis and treatment of depression]. G Nowak, A Zieba, D Dudek, M Schlegel-Zawadzka, A Pilc
Psychiatria polska,
PMID:11490890

Anxiolytic-like effects of group I metabotropic glutamate antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) in rats. A Kłodzińska, E Tatarczyńska, E Chojnacka-Wójcik, A Pilc
Polish journal of pharmacology,
PMID:11334240

Influence of chronic imipramine administration on the CaM-KII activity in postsynaptic densities and synaptosomal plasma membrane fraction isolated from the rat frontal cortex and hippocampus. P Brański, A Pałucha, J Wierońska, B Kroczka, B Kownacka, A Pilc
Polish journal of pharmacology,
PMID:11334242

Antidepressant-like properties of zinc in rodent forced swim test. B Kroczka, P Branski, A Palucha, A Pilc, G Nowak
Brain research bulletin,
PMID:11470330

Possible involvement of mGluR1 together with group II and III mGluRs in ibotenate-stimulated cAMP formation in the rat brain cortical slices. A Pałucha, P Brański, B Kroczka, A Pilc
Polish journal of pharmacology,
PMID:11334227

Zinc exhibits an antidepressant-like effect in the forced swimming test in mice. B Kroczka, A Zieba, D Dudek, A Pilc, G Nowak
Polish journal of pharmacology,
PMID:11334234

(S)-4C3HPG, a mixed group I mGlu receptor antagonist and a group II agonist, administered intrastriatally, counteracts parkinsonian-like muscle rigidity in rats. E Lorenc-Koci, J Wardas, S Wolfarth, A Pilc
Brain research,
PMID:11382401

Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist. E Tatarczyńska, A Klodzińska, E Chojnacka-Wójcik, A Palucha, F Gasparini, R Kuhn, A Pilc
British journal of pharmacology,
PMID:11264235

Stimulation of group II metabotropic glutamate receptors or inhibition of group I ones exerts anxiolytic-like effects in rats. A Pilc, E Chojnacka-Wójcik, E Tatarczyńska, J Borycz, B Kroczka
Amino acids,
PMID:11026476

The role of glutamate receptors in antipsychotic drug action. K Ossowska, M Pietraszek, J Wardas, G Nowak, W Zajaczkowski, S Wolfarth, A Pilc
Amino acids,
PMID:11026477

The role of metabotropic glutamate receptor (mGluR) ligands in parkinsonian muscle rigidity. S Wolfarth, J Konieczny, E Lorenc-Koci, K Ossowska, A Pilc
Amino acids,
PMID:11026478

Selective agonist of group II glutamate metabotropic receptors, LY354740, inhibits tolerance to analgesic effects of morphine in mice. P Popik, E Kozela, A Pilc
British journal of pharmacology,
PMID:10903986

Effect of chronic antidepressant or electroconvulsive shock treatment on mGLuR1a immunoreactivity expression in the rat hippocampus. M Bajkowska, P Brański, M Smiałowska, A Pilc
Polish journal of pharmacology,
PMID:10817534

Selective group II glutamate metabotropic receptor agonist LY354740 attenuates pentetrazole- and picrotoxin-induced seizures. A Kłodzińska, E Chojnacka-Wójcik, A Pilc
Polish journal of pharmacology,
PMID:10817535

Differential effects of NMDA-receptor antagonists on long-term potentiation and hypoxic/hypoglycaemic excitotoxicity in hippocampal slices. T Frankiewicz, A Pilc, C G Parsons
Neuropharmacology,
PMID:10728884

Roles of group II metabotropic glutamate receptors in modulation of seizure activity. A Kłodzińska, M Bijak, E Chojnacka-Wójcik, B Kroczka, M Swiader, S J Czuczwar, A Pilc
Naunyn-Schmiedeberg's archives of pharmacology,
PMID:10731041

Potential anti-anxiety, anti-addictive effects of LY 354740, a selective group II glutamate metabotropic receptors agonist in animal models. A Kłodzińska, E Chojnacka-Wójcik, A Pałucha, P Brański, P Popik, A Pilc
Neuropharmacology,
PMID:10608278

The effect of prolonged imipramine and electroconvulsive shock treatment on calcium/calmodulin-dependent protein kinase II in the hippocampus of rat brain. A Pilc, P Branski, A Palucha, J Aronowski
Neuropharmacology,
PMID:10221763

LY354740, a group II metabotropic glutamate receptor agonist with potential antiparkinsonian properties in rats. J Konieczny, K Ossowska, S Wolfarth, A Pilc
Naunyn-Schmiedeberg's archives of pharmacology,
PMID:9826074

Antidepressant treatment influences group I of glutamate metabotropic receptors in slices from hippocampal CA1 region. A Pilc, P Brański, A Pałucha, K Tokarski, M Bijak
European journal of pharmacology,
PMID:9669500

Influence of imipramine treatment on the group I of metabotropic glutamate receptors in CA1 region of hippocampus. A Pałucha, P Brański, K Tokarski, M Bijak, A Pilc
Polish journal of pharmacology,
PMID:9566055

The anxiolytic-like effect of metabotropic glutamate receptor antagonists after intrahippocampal injection in rats. E Chojnacka-Wójcik, E Tatarczyńska, A Pilc
European journal of pharmacology,
PMID:9042585

The enhancement and the inhibition of noradrenaline-induced cyclic AMP accumulation in rat brain by stimulation of metabotropic glutamate receptors. B Legutko, A Pałucha, P Branski, A Pilc
Acta physiologica Hungarica,
PMID:9219617

Anxiolytic-like effects of metabotropic glutamate antagonist (RS)-alpha-methylserine-O-phosphate in rats. E Chojnacka-Wójcik, E Tatarczyńska, A Pilc
Polish journal of pharmacology,
PMID:9112693

The enhancement and the inhibition of noradrenaline-induced cyclic AMP accumulation in rat brain by stimulation of metabotropic glutamate receptors. A Pilc, B Legutko, A Czyrak
Progress in neuro-psychopharmacology & biological psychiatry,
PMID:8843491

The influence of prolonged antidepressant treatment on the changes in cyclic AMP accumulation induced by excitatory amino acids in rat cerebral cortical slices. A Pilc, B Legutko
Neuroreport,
PMID:8742423

Antidepressant treatment influences cyclic AMP accumulation induced by excitatory amino acids in rat brain. A Pilc, B Legutko
Polish journal of pharmacology,
PMID:8616518

The effect of interaction between (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R)-ACPD and noradrenaline on cyclic AMP accumulation: different actions in brain slices, primary glial and neuronal cell cultures. A Pilc, B Legutko, T Frankiewicz, A Czyrak
Polish journal of pharmacology,
PMID:7550553

Trans-(+-)-1-amino-1,3-cyclopentanedicarboxylate (trans-ACPD) stimulates cAMP accumulation in rat cerebral cortical slices but not in glial or neuronal cultures. A Pilc, B Legutko, T Frankiewicz, A Czyrak
Neuroscience letters,
PMID:8047276

The effect of chronic treatment with imipramine, ECS and nifedipine on the beta-adrenergic function in the rat hippocampal slices. T Frankiewicz, B Legutko, A Czyrak, A Pilc
Polish journal of pharmacology,
PMID:8401775

Chronic effects of imipramine and nifedipine on the beta-adrenergic function in neuronal and glial primary cultures. B Legutko, T Frankiewicz, A Czyrak, A Pilc
Polish journal of pharmacology,
PMID:8401776

N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, an irreversible receptor inactivator, as a tool for measurement of alpha 2-adrenoceptor occupancy in vivo. A Pilc, G Nowak, J Zak
European journal of pharmacology,
PMID:1348228

Pretreatment with N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline accelerates the electroshock-induced decrease in density of beta-adrenoceptors but not functional downregulation. A Pilc, J Vetulani
Neuropharmacology,
PMID:1972550

Antidepressant profile of 9-methyl-2[-3-(4-phenyl-1-piperazinylpropyl)]-1,2,3,4-tetrahydro-beta- carbolin-1-one (B-193). B Wiczyńska, L Antkiewicz-Michaluk, A Pilc, E Chojnacka-Wójcik, E Przegaliński
Polish journal of pharmacology and pharmacy,
PMID:2636891

An in vivo procedure for the selective inactivation of rat brain cerebral cortical alpha-adrenoceptors using N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ). A Pilc, J Vetulani, S Nomura, S J Enna
Brain research,
PMID:2570619

Reserpinization enhances electroconvulsive treatment effects on cortical alpha 1-adrenoceptors. A Pilc, I Nalepa, J Vetulani
European journal of pharmacology,
PMID:2852115

A comparison of norepinephrine stimulated inositol phosphate accumulation in cerebral cortex of the Acomys cahirinus, the laboratory mice and the rat. I Nalepa, A Pilc, E Chalecka-Franciszek, J Vetulani
Polish journal of pharmacology and pharmacy,
PMID:3222183

The influence of electroshock on adrenoceptor function in rat brain cerebral cortex: selectivity for the alpha-adrenoceptor site. A Pilc, E Chalecka-Franaszek, I Nalepa, J Vetulani, S J Enna
European journal of pharmacology,
PMID:2850206

The role of alpha 2-adrenoceptors in the mechanism of action of antidepressant drugs. A Pilc
Polish journal of pharmacology and pharmacy,
PMID:2847126

Supersensitive beta-adrenergic receptors are down-regulated in rat brain by mianserin administration. A Pilc, S J Enna
Journal of neural transmission,
PMID:2822849

Antidepressant administration has a differential effect on rat brain alpha 2-adrenoceptor sensitivity to agonists and antagonists. A Pilc, S J Enna
European journal of pharmacology,
PMID:2880736

Activation of alpha-2 adrenergic receptors augments neurotransmitter-stimulated cyclic AMP accumulation in rat brain cerebral cortical slices. A Pilc, S J Enna
The Journal of pharmacology and experimental therapeutics,
PMID:2872324

Upregulation of gamma-aminobutyric acid (GABA) B binding sites in rat frontal cortex: a common action of repeated administration of different classes of antidepressants and electroshock. K G Lloyd, F Thuret, A Pilc
The Journal of pharmacology and experimental therapeutics,
PMID:2995646

Synergistic interaction between alpha- and beta-adrenergic receptors in rat brain slices: possible site for antidepressant drug action. A Pilc, S J Enna
Life sciences,
PMID:2995740

Chronic antidepressants and GABA A Pilc, K G Lloyd
Life sciences,
PMID:6092815

Alpha up-beta down adrenergic regulation: a possible mechanism of action of antidepressant treatments. J Vetulani, L Antkiewicz-Michaluk, A Rokosz-Pelc, A Pilc
Polish journal of pharmacology and pharmacy,
PMID:6089158

Electroshock-induced increase in [3H]prazosin binding to cortical membranes in reserpinized rats. A Pilc, A Rokosz-Pelc, J Vetulani
European journal of pharmacology,
PMID:6723780

Chronic electroconvulsive treatment enhances the density of [3H]prazosin binding sites in the central nervous system of the rat. J Vetulani, L Antkiewicz-Michaluk, A Rokosz-Pelc, A Pilc
Brain research,
PMID:6684967

Spaced electroconvulsive treatment: effects on responses associated with alpha 2- and 5-HT2-receptors. J Vetulani, J Szpak, A Pilc
The Journal of pharmacy and pharmacology,
PMID:6134806

Chronic treatment with imipramine: further functional evidence for the enhanced noradrenergic transmission in flexor reflex activity. J Maj, Z Górka, M Melzacka, A Rawłów, A Pilc
Naunyn-Schmiedeberg's archives of pharmacology,
PMID:6306487

The attenuation by chronic electroconvulsive treatment of hypothermia induced by histamine H2-receptor stimulants in rats. A Pilc, A Rokosz-Pelc
European journal of pharmacology,
PMID:6221937

Postdecapitation convulsions in the rat measured with an Animex motility meter: relation to central alpha-adrenoceptors. J Vetulani, A Pilc
European journal of pharmacology,
PMID:6129989

Histidine-induced bizarre behaviour in rats: the possible involvement of central cholinergic system. A Pilc, Z Rogóz, G Skuza
Neuropharmacology,
PMID:7121750

Cataleptogenic doses of morphine suppress 3H-spiroperidol binding to striatal membranes. K Golembiowska-Nikitin, A Pilc, J Vetulani
Naunyn-Schmiedeberg's archives of pharmacology,
PMID:7202125

Depression by chronic electroconvulsive treatment of clonidine hypotherma and [3H]clonidine binding to rat cortical membranes. A Pilc, J Vetulani
European journal of pharmacology,
PMID:6284527

Attenuation by chronic imipramine treatment of [3H]clonidine binding to cortical membranes and of clonidine-induced hypothermia: the influence of central chemosympathectomy. A Pilc, J Vetulani
Brain research,
PMID:6284303

The histamine-induced skin reaction in schizophrenic and normal subjects. R W Schayer, A Pilc, A Zaborwski, W Kazimierczak, C Maslinski
The Journal of clinical psychiatry,
PMID:7054159

Enhancement of responsiveness of the central serotonergic system and serotonin-2 receptor density in rat frontal cortex by electroconvulsive treatment. J Vetulani, U Lebrecht, A Pilc
European journal of pharmacology,
PMID:7318923

The effect of multiple imipramine administration on monoaminergic systems of the rat brain. J Vetulani, L Antkiewicz-Michaluk, K Gołembiowska-Nikitin, J Michaluk, A Pilc, A Rokosz
Polish journal of pharmacology and pharmacy,
PMID:6265887

The hyperthermic phase of histamine action in rats. A Pilc, J Z Nowak
Polish journal of pharmacology and pharmacy,
PMID:7255265

Rapid-eye-movement sleep deprivation inhibits clonidine-induced sedation in rats. E Mogilnicka, A Pilc
European journal of pharmacology,
PMID:7238581

Some central effects of impromidine, a potent agonist of histamine H2 receptors. A Pilc, Z Rogóz, B Byrska
Neuropharmacology,
PMID:6158709

The influence of 4-methylhistamine, an agonist of histamine H2 receptors on body temperature in rats. A Pilc, J Z Nowak
Neuropharmacology,
PMID:6448357

Opiates and specific receptor binding of [3H]clonidine. K Golembiowska-Nikitin, A Pilc, J Vetulani
The Journal of pharmacy and pharmacology,
PMID:6102136

Effect of histamine H2-receptor antagonists on concentration of noradrenaline, dopamine, 3,4-dihydroxyphenylacetic acid, serotonin and 5-hydroxyindoleacetic acid in rat brain. J Z Nowak, A Pilc
Polish journal of pharmacology and pharmacy,
PMID:42886

Two possible binding sites for 3H-clonidine in the rat cerebral cortex. J Vetulani, M Nielsen, A Pilc, K Goøembiowska-Nikitin
European journal of pharmacology,
PMID:499341

The action of histamine, histamine H1-and H2-receptor agonists on noradrenaline level in rat brain. J Z Nowak, A Pilc
Polish journal of pharmacology and pharmacy,
PMID:493177

Some behavioral effects of histamine H1-, and H2-receptor agonists in rats. J Z Nowak, A Pilc
Polish journal of pharmacology and pharmacy,
PMID:493178

Negligible binding of 3H-clonidine to histamine H2 receptor. A Pilc, K Gołembiowska-Nikitin, J Vetulani
European journal of pharmacology,
PMID:467507

The influence of histamine H2-receptor antagonists on monoaminergic systems in rat brain [proceedings]. J Z Nowak, A Pilc
Agents and actions,
PMID:37729

Influence of histamine on the serotonergic system of rat brain. A Pilc, J Z Nowak
European journal of pharmacology,
PMID:456425

A possible serotoninergic link in the hypothermic action of histamine [proceedings]. A Pilc, J Z Nowak
Agents and actions,
PMID:463709

An interaction of histamine H2-receptor antagonists with the noradrenergic system in rat brain. J Z Nowak, A Pilc, C Maśliński
European journal of pharmacology,
PMID:29763

Direct or indirect action of histamine on dopamine metabolism in the rat striatum? J Z Nowak, A Pilc
European journal of pharmacology,
PMID:590328

Separation of acetylcholine and catecholamine containing synaptic vesicles from brain cortex. A Nagy, G Várady, F Joó, Z Rakonczay, A Pilc
Journal of neurochemistry,
PMID:894301

The influence of mepyramine and burimamide on histamine induced catalepsy in the rat. J Z Nowak, A Pilc
Acta physiologica Polonica,
PMID:1241504

Histamine content and synthesis in central and pheripheral nerve structures during stress. C Maśliński, B Bielkiewicz, J Z Nowak, A Pilc
Agents and actions,
PMID:1180176

The influence of histamine liberator compound 48/80 on histamine level in sciatic nerve of the rat. A Pilc, J Z Nowak
Acta physiologica Polonica,
PMID:4456973

Catalepsia-like symptoms produced by histidine in rats. C Maśliński, U Lebrecht, J Z Nowak, A Pilc, Z Wieczorek-Fila
Agents and actions,
PMID:4798894

Effect of histidine on the formation of catalepsia-like symptoms in rats. J Z Nowak, A Pilc, Z Wieczorek-Fila, C Maśliński
Acta physiologica Polonica,
PMID:4795521

Professor Andrzej Pilc, PhD

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