Agnieszka Pałucha - Poniewiera, PhD
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The involvement of monoaminergic neurotransmission in the antidepressant-like action of scopolamine in the tail suspension test.
Agnieszka Pałucha-Poniewiera, Karolina Podkowa, Tomasz Lenda, Andrzej Pilc
Progress in neuro-psychopharmacology & biological psychiatry, S0278-5846(17)30220-8 10.1016/j.pnpbp.2017.06.022
PMID:28647535
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Antidepressant-like effects of scopolamine in mice are enhanced by the group II mGlu receptor antagonist LY341495.
Karolina Podkowa, Adrian Podkowa, Kinga Sałat, Tomasz Lenda, Andrzej Pilc, Agnieszka Pałucha-Poniewiera
Neuropharmacology, S0028-3908(16)30367-7 10.1016/j.neuropharm.2016.08.031
PMID:27569995
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Glutamate-Based Drug Discovery for Novel Antidepressants.
Agnieszka Pałucha-Poniewiera, Andrzej Pilc
Expert opinion on drug discovery, 10.1080/17460441.2016.1213234
PMID:27409299
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Group II mGlu receptor antagonist LY341495 enhances the antidepressant-like effects of ketamine in the forced swim test in rats.
Karolina Podkowa, Bartłomiej Pochwat, Piotr Brański, Andrzej Pilc, Agnieszka Pałucha-Poniewiera
Psychopharmacology, 10.1007/s00213-016-4325-7
PMID:27286960
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Activation of mTOR dependent signaling pathway is a necessary mechanism of antidepressant-like activity of zinc.
Bernadeta Szewczyk, Bartłomiej Pochwat, Anna Rafało, Agnieszka Palucha-Poniewiera, Helena Domin, Gabriel Nowak
Neuropharmacology, 10.1016/j.neuropharm.2015.08.026 S0028-3908(15)30071-X
PMID:26297535
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A novel mGlu4 selective agonist LSP4-2022 increases behavioral despair in mouse models of antidepressant action.
Karolina Podkowa, Szymon Rzeźniczek, Marcin Marciniak, Francine Acher, Andrzej Pilc, Agnieszka Pałucha-Poniewiera
Neuropharmacology, 10.1016/j.neuropharm.2015.05.039 S0028-3908(15)00242-7
PMID:26074092
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Is the mGlu5 receptor a possible target for new antidepressant drugs?
Agnieszka Pałucha-Poniewiera, Joanna M Wierońska, Piotr Brański, Grzegorz Burnat, Barbara Chruścicka, Andrzej Pilc
Pharmacological reports : PR,
PMID:24552998
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NMDA antagonists under investigation for the treatment of major depressive disorder.
Bartłomiej Pochwat, Agnieszka Pałucha-Poniewiera, Bernadeta Szewczyk, Andrzej Pilc, Gabriel Nowak
Expert opinion on investigational drugs, 10.1517/13543784.2014.918951
PMID:24818801
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Prolonged administration of antidepressant drugs leads to increased binding of [(3)H]MPEP to mGlu5 receptors.
Gabriel Nowak, Lucyna Pomierny-Chamioło, Agata Siwek, Ewa Niedzielska, Bartosz Pomierny, Agnieszka Pałucha-Poniewiera, Andrzej Pilc
Neuropharmacology, 10.1016/j.neuropharm.2014.04.016 S0028-3908(14)00152-X
PMID:24796254
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Activation of the mTOR signaling pathway in the antidepressant-like activity of the mGlu5 antagonist MTEP and the mGlu7 agonist AMN082 in the FST in rats.
Agnieszka Pałucha-Poniewiera, Bernadeta Szewczyk, Andrzej Pilc
Neuropharmacology, 10.1016/j.neuropharm.2014.03.001 S0028-3908(14)00085-9
PMID:24631968
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The antidepressant-like action of mGlu5 receptor antagonist, MTEP, in the tail suspension test in mice is serotonin dependent.
Agnieszka Pałucha-Poniewiera, Piotr Brański, Joanna M Wierońska, Katarzyna Stachowicz, Anna Sławińska, Andrzej Pilc
Psychopharmacology,
PMID:23958941
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A selective mGlu7 receptor antagonist MMPIP reversed antidepressant-like effects of AMN082 in rats.
Agnieszka Pałucha-Poniewiera, Andrzej Pilc
Behavioural brain research, 10.1016/j.bbr.2012.10.004 S0166-4328(12)00643-2
PMID:23085340
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Involvement of mGlu5 and NMDA receptors in the antidepressant-like effect of acamprosate in the tail suspension test.
Agnieszka Pałucha-Poniewiera, Andrzej Pilc
Progress in neuro-psychopharmacology & biological psychiatry, 10.1016/j.pnpbp.2012.05.015
PMID:22651960
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mGlu2/3 and mGlu5 receptors: potential targets for novel antidepressants.
Shigeyuki Chaki, Yukio Ago, Agnieszka Palucha-Paniewiera, Francesco Matrisciano, Andrzej Pilc
Neuropharmacology, 10.1016/j.neuropharm.2012.05.022 S0028-3908(12)00220-1
PMID:22640631
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Anxiolytic- but not antidepressant-like activity of Lu AF21934, a novel, selective positive allosteric modulator of the mGlu₄ receptor.
Anna Sławińska, Joanna M Wierońska, Katarzyna Stachowicz, Agnieszka Pałucha-Poniewiera, Michelle A Uberti, Maria A Bacolod, Dario Doller, Andrzej Pilc
Neuropharmacology, 10.1016/j.neuropharm.2012.05.001 S0028-3908(12)00174-8
PMID:22634361
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Investigational NMDA receptor modulators for depression.
Bernadeta Szewczyk, Agnieszka Pałucha-Poniewiera, Ewa Poleszak, Andrzej Pilc, Gabriel Nowak
Expert opinion on investigational drugs, 10.1517/13543784.2012.638916
PMID:22097925
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On the mechanism of anti-hyperthermic effects of LY379268 and LY487379, group II mGlu receptors activators, in the stress-induced hyperthermia in singly housed mice.
J M Wierońska, K Stachowicz, P Brański, A Pałucha-Poniewiera, A Pilc
Neuropharmacology, 10.1016/j.neuropharm.2011.07.042
PMID:21855555
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Metabotropic glutamate receptor 4 novel agonist LSP1-2111 with anxiolytic, but not antidepressant-like activity, mediated by serotonergic and GABAergic systems.
Joanna M Wierońska, Katarzyna Stachowicz, Agnieszka Pałucha-Poniewiera, Francine Acher, Piotr Brański, Andrzej Pilc
Neuropharmacology, 10.1016/j.neuropharm.2010.08.008
PMID:20713068
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On the mechanism of the antidepressant-like action of group II mGlu receptor antagonist, MGS0039.
Agnieszka Pałucha-Poniewiera, Joanna M Wierońska, Piotr Brański, Katarzyna Stachowicz, Shigeyuki Chaki, Andrzej Pilc
Psychopharmacology, 10.1007/s00213-010-1978-5
PMID:20703449
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The antidepressant-like action of metabotropic glutamate 7 receptor agonist N,N'-bis(diphenylmethyl)-1,2-ethanediamine (AMN082) is serotonin-dependent.
Agnieszka Pałucha-Poniewiera, Piotr Brański, Tomasz Lenda, Andrzej Pilc
The Journal of pharmacology and experimental therapeutics, 10.1124/jpet.110.169730
PMID:20562216
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Group III mGlu receptor agonist, ACPT-I, attenuates morphine-withdrawal symptoms after peripheral administration in mice.
Agnieszka Pałucha-Poniewiera, Kinga Novák, Andrzej Pilc
Progress in neuro-psychopharmacology & biological psychiatry, 10.1016/j.pnpbp.2009.07.029
PMID:19660510
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The group III mGlu receptor agonist ACPT-I exerts anxiolytic-like but not antidepressant-like effects, mediated by the serotonergic and GABA-ergic systems.
K Stachowicz, A Kłodzińska, A Palucha-Poniewiera, S Schann, P Neuville, A Pilc
Neuropharmacology, 10.1016/j.neuropharm.2009.06.005
PMID:19539634
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Peripheral administration of group III mGlu receptor agonist ACPT-I exerts potential antipsychotic effects in rodents.
A Pałucha-Poniewiera, A Kłodzińska, K Stachowicz, K Tokarski, G Hess, S Schann, M Frauli, P Neuville, A Pilc
Neuropharmacology, 10.1016/j.neuropharm.2008.06.033
PMID:18619473
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Antidepressant-like activity of 8-Br-cAMP, a PKA activator, in the forced swim test.
Piotr Brański, Agnieszka Palucha, Bernadeta Szewczyk, Joanna M Wierońska, Andrzej Pilc, Gabriel Nowak
Journal of neural transmission (Vienna, Austria : 1996), 10.1007/s00702-008-0023-x
PMID:18239846
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Chronic imipramine treatment reduces inhibitory properties of group II mGlu receptors without affecting their density or affinity.
Agnieszka Pałucha, Piotr Brański, Kinga Kĺak, Magdalena Sowa
Pharmacological reports : PR,
PMID:18048952
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Citalopram influences mGlu7, but not mGlu4 receptors' expression in the rat brain hippocampus and cortex.
Joanna M Wierońska, Kinga Kłak, Agnieszka Pałucha, Piotr Brański, Andrzej Pilc
Brain research,
PMID:17976546
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Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
Agnieszka Palucha, Kinga Klak, Piotr Branski, Herman van der Putten, Peter J Flor, Andrzej Pilc
Psychopharmacology,
PMID:17622518
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Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs.
Agnieszka Palucha, Andrzej Pilc
Pharmacology & therapeutics,
PMID:17582504
-
Selective mGlu5 receptor antagonist MTEP attenuates naloxone-induced morphine withdrawal symptoms.
Agnieszka Pałucha, Piotr Brański, Andrzej Pilc
Polish journal of pharmacology,
PMID:15662102
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Are compounds acting at metabotropic glutamate receptors the answer to treating depression?
Agnieszka Palucha
Expert opinion on investigational drugs,
PMID:17107280
-
Antidepressant-like activity of CGP 36742 and CGP 51176, selective GABAB receptor antagonists, in rodents.
G Nowak, A Partyka, A Pałucha, B Szewczyk, J M Wierońska, M Dybała, M Metz, T Librowski, W Froestl, M Papp, A Pilc
British journal of pharmacology,
PMID:16921399
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Combined administration of PHCCC, a positive allosteric modulator of mGlu4 receptors and ACPT-I, mGlu III receptor agonist evokes antidepressant-like effects in rats.
K Kłak, A Pałucha, P Brański, M Sowa, A Pilc
Amino acids,
PMID:16868652
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Anxiolytic action of group II and III metabotropic glutamate receptors agonists involves neuropeptide Y in the amygdala.
Joanna M Wierońska, Bernadeta Szewczyk, Agnieszka Pałucha, Piotr Brański, Barbara Zieba, Maria Smiałowska
Pharmacological reports : PR,
PMID:16382191
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Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist.
Agnieszka Pałucha, Piotr Brański, Bernadeta Szewczyk, Joanna M Wierońska, Kinga Kłak, Andrzej Pilc
Pharmacology, biochemistry, and behavior,
PMID:16040106
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The involvement of glutamate in the pathophysiology of depression.
A Palucha, A Pilc
Drug news & perspectives,
PMID:16034483
-
Group III mGlu receptor agonists produce anxiolytic- and antidepressant-like effects after central administration in rats.
A Pałucha, E Tatarczyńska, P Brański, B Szewczyk, J M Wierońska, K Kłak, E Chojnacka-Wójcik, G Nowak, A Pilc
Neuropharmacology,
PMID:14680755
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In the amygdala anxiolytic action of mGlu5 receptors antagonist MPEP involves neuropeptide Y but not GABAA signaling.
Joanna M Wierońska, Maria Smiałowska, Piotr Brański, Fabrizio Gasparini, Aleksandra Kłodzińska, Bernadeta Szewczyk, Agnieszka Pałucha, Ewa Chojnacka-Wójcik, Andrzej Pilc
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
PMID:14666119
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Antidepressant-like effect of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist in the olfactory bulbectomized rats.
J M Wieronska, B Szewczyk, P Branski, A Palucha, A Pilc
Amino acids,
PMID:12373540
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Involvement of CRF but not NPY in the anxiety regulation via NMDA receptors.
Joanna M Wierońska, Bernadeta Szewczyk, Agnieszka Pałucha, Piotr Brański, Maria Smiałowska
Polish journal of pharmacology,
PMID:14730109
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Antidepressant-like effects of acute and chronic treatment with zinc in forced swim test and olfactory bulbectomy model in rats.
Gabriel Nowak, Bernadeta Szewczyk, Joanna M Wieronska, Piotr Branski, Agnieszka Palucha, Andrzej Pilc, Krystyna Sadlik, Wojciech Piekoszewski
Brain research bulletin,
PMID:12832002
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On the role of metabotropic glutamate receptors in the mechanisms of action of antidepressants.
Agnieszka Pałucha, Andrzej Pilc
Polish journal of pharmacology,
PMID:12866712
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Interaction of zinc with antidepressants in the forced swimming test in mice.
Bernadeta Szewczyk, Piotr Brański, Joanna M Wierońska, Agnieszka Pałucha, Andrzej Pilc, Gabriel Nowak
Polish journal of pharmacology,
PMID:12866724
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Anxiolytic- and antidepressant-like effects of group III metabotropic glutamate agonist (1S,3R,4S)-1-aminocyclopentane-1,3,4-tricarboxylic acid (ACPT-I) in rats.
Ewa Tatarczyńska, Agnieszka Pałucha, Bernadeta Szewczyk, Ewa Chojnacka-Wójcik, Joanna Wierońska, Andrzej Pilc
Polish journal of pharmacology,
PMID:12866729
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Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats.
A Pilc, A Kłodzińska, P Brański, G Nowak, A Pałucha, B Szewczyk, E Tatarczyńska, E Chojnacka-Wójcik, J M Wierońska
Neuropharmacology,
PMID:12213272
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Effect of chronic imipramine or electroconvulsive shock on the expression of mGluR1a and mGluR5a immunoreactivity in rat brain hippocampus.
M Smiałowska, B Szewczyk, P Brański, J M Wierońska, A Pałucha, M Bajkowska, A Pilc
Neuropharmacology,
PMID:12128002
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Changes in the expression of metabotropic glutamate receptor 5 (mGluR5) in the rat hippocampus in an animal model of depression.
J M Wierońska, P Brański, B Szewczyk, A Pałucha, M Papp, P Gruca, E Moryl, A Pilc
Polish journal of pharmacology,
PMID:11985342
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Developmental changes in the modulation of cyclic amp accumulation by activation of metabotropic glutamate receptors.
A Pałucha, P Brański, B Kroczka, J Wierońska, A Pilc
Polish journal of pharmacology,
PMID:11990066
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Intracellular distribution of psychotropic drugs in the grey and white matter of the brain: the role of lysosomal trapping.
W A Daniel, J Wójcikowski, A Pałucha
British journal of pharmacology,
PMID:11606321
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Influence of chronic imipramine administration on the CaM-KII activity in postsynaptic densities and synaptosomal plasma membrane fraction isolated from the rat frontal cortex and hippocampus.
P Brański, A Pałucha, J Wierońska, B Kroczka, B Kownacka, A Pilc
Polish journal of pharmacology,
PMID:11334242
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Antidepressant-like properties of zinc in rodent forced swim test.
B Kroczka, P Branski, A Palucha, A Pilc, G Nowak
Brain research bulletin,
PMID:11470330
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Possible involvement of mGluR1 together with group II and III mGluRs in ibotenate-stimulated cAMP formation in the rat brain cortical slices.
A Pałucha, P Brański, B Kroczka, A Pilc
Polish journal of pharmacology,
PMID:11334227
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Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist.
E Tatarczyńska, A Klodzińska, E Chojnacka-Wójcik, A Palucha, F Gasparini, R Kuhn, A Pilc
British journal of pharmacology,
PMID:11264235
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Potential anti-anxiety, anti-addictive effects of LY 354740, a selective group II glutamate metabotropic receptors agonist in animal models.
A Kłodzińska, E Chojnacka-Wójcik, A Pałucha, P Brański, P Popik, A Pilc
Neuropharmacology,
PMID:10608278
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The effect of prolonged imipramine and electroconvulsive shock treatment on calcium/calmodulin-dependent protein kinase II in the hippocampus of rat brain.
A Pilc, P Branski, A Palucha, J Aronowski
Neuropharmacology,
PMID:10221763
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Comparison of the effects of low and high concentrations of group I metabotropic receptor agonists on field potentials in the hippocampal CA1 region in vitro.
A Zahorodna, A Pałucha, M Bijak
Polish journal of pharmacology,
PMID:10091713
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Antidepressant treatment influences group I of glutamate metabotropic receptors in slices from hippocampal CA1 region.
A Pilc, P Brański, A Pałucha, K Tokarski, M Bijak
European journal of pharmacology,
PMID:9669500
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Influence of imipramine treatment on the group I of metabotropic glutamate receptors in CA1 region of hippocampus.
A Pałucha, P Brański, K Tokarski, M Bijak, A Pilc
Polish journal of pharmacology,
PMID:9566055
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The enhancement and the inhibition of noradrenaline-induced cyclic AMP accumulation in rat brain by stimulation of metabotropic glutamate receptors.
B Legutko, A Pałucha, P Branski, A Pilc
Acta physiologica Hungarica,
PMID:9219617
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