CONTENTS (PDF format)

MINIREVIEW - Treatment of depression: clinical aspects. Dominika Dudek (p. 1) Abstract / Article (PDF format) Effect of antidepressants on the phospholipase A2 activity in plasma membranes of the rat brain cortex. Krzysztof Kucia, Andrzej Małecki, Bożena Gabryel, Henryk I. Trzeciak (p. 5) Abstract / Article (PDF format) Exploratory activity and a conditioned fear response: correlation with cortical and subcortical binding of the alpha4beta2 nicotinic receptor agonist [3H]-epibatidine. Halina Sienkiewicz-Jarosz, Piotr Maciejak, Andrzej Bidziński, Janusz Szyndler, Marek Siemiątkowski, Agnieszka Członkowska, Małgorzata Lehner, Adam Płaźnik (p. 17) Abstract / Article (PDF format) Effects of calcium and magnesium on peripheral nerve conduction. Tufan Mert, Yasemin Gunes, Mustafa Guven, Ismail Gunay, Dilek Ozcengiz (p. 25) Abstract / Article (PDF format) Enhancement of circulatory antioxidants by alpha-ketoglutarate during sodium valproate treatment in Wistar rats. Murugesan Vidya, Perumal Subramanian (p. 31) Abstract / Article (PDF format) S-allylcysteine inhibits circulatory lipid peroxidation and promotes antioxidants in N-nitrosodiethylamine-induced carcinogenesis. Sivapatham Sundaresan, Perumal Subramanian (p. 37) Abstract / Article (PDF format) Effect of Casearia esculenta root extract on blood glucose and plasma antioxidant status in streptozotocin diabetic rats. Annamalai Prakasam, Subramaniam Sethupathy, Kodukkur V. Pugalendi (p. 43) Abstract / Article (PDF format) Effects of local anesthetics on pregnant uterine muscles. Bilge Karsli, Nurten Kayacan, Zuhal Kucukyavuz, Caner Mimaroglu (p. 51) Abstract / Article (PDF format) Effect of erythromycin on contractile response of uterine smooth muscle strips in non-pregnant rats. Heng Liu, Tianmin Zhu, Yongming Ma, Songyi Qu (p. 57) Abstract / Article (PDF format) Effects of simvastatin on the development of osteopenia caused by ovariectomy in rats. Maria Pytlik, Waldemar Janiec, Małgorzata Misiarz-Myrta, Iwona Gubała (p. 63) Abstract / Article (PDF format) Ischemic and pharmacological induction of delayed cellular protection in inos gene-disrupted mice myocytes. Mohammed A. Nayeem, Syed J. Mustafa (p. 73) Abstract / Article (PDF format) Comparative pharmacokinetics of propranolol and atenolol in primary hyperlipidemia. Bogumiła Telatyńska, Jerzy Wójcicki, Marek Droździk, Barbara Gawrońska-Szklarz, Violetta Sulżyc-Bielicka, Rozalia Sterna (p. 81) Abstract / Article (PDF format) SHORT COMMUNICATIONS Antiulcer activity of levcromakalim and nicorandil in albino rats: a comparative study. Manoj Bose, Vijay M. Motghare, Ganesh N. Dakhale, Avinash V. Turankar (p. 91) Abstract / Article (PDF format) Relationship between the level and time of exposure to tobacco smoke and urine nicotine and cotinine concentration. Ewa Florek, Wojciech Piekoszewski, Jagna Wrzosek (p. 97) Abstract / Article (PDF format) Influence of LY 300164, an AMPA/kainate receptor antagonist upon the anticonvulsant action of antiepileptic drugs against aminophylline-induced seizures in mice. Mariusz Świąder, Hubert Kuźniar, Zdzisław Kleinrok, Stanisław J. Czuczwar (p. 103) Abstract / Article (PDF format) PRELIMINARY COMMUNICATION 1-Methylnicotinamide: a potent anti-inflammatory agent of vitamin origin. Jerzy Gębicki, Anna Sysa-Jędrzejowska, Jan Adamus, Anna Woźniacka, Małgorzata Rybak, Jacek Zielonka (p. 109) Abstract / Article (PDF format) Abstracts of Seventh Conference on PROGRESS IN ETIOPATHOGENESIS OF SEIZURES (p. 115) (PDF format)

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OBITUARY - Professor Jerzy Maj, M.D., Ph.D. (1922–2003). Edmund Przegaliński, Jerzy Vetulani (p. 127) (PDF format) OBITUARY - Dr. Anna Czyrak (1957–2003). Edmund Przegaliński (p. 131) (PDF format) REVIEW - Significance of dysfunctional glutamatergic transmission for the development of psychotic symptoms. Małgorzata Pietraszek (p. 133) Abstract / Article (PDF format) Synergistic effect of SCH 58261, an adenosine A2A receptor antagonist, and L-DOPA on the reserpine-induced muscle rigidity in rats. Jadwiga Wardas (p. 155) Abstract / Article (PDF format) Lack of changes in cortical [3H]-muscimol binding in rats sensitized to nicotine-induced enhancement of dopamine metabolism. Halina Sienkiewicz-Jarosz, Agnieszka I. Członkowska, Małgorzata Lehner, Piotr Maciejak, Marek Siemiątkowski, Janusz Szyndler, Aleksandra Wisłowska, Małgorzata Zienowicz, Andrzej Bidziński, Wojciech Kostowski, Adam Płaźnik (p. 165) Abstract / Article (PDF format) Influence of AIDA on certain behaviors in rats subjected to experimental hypoxia. Agnieszka Nadlewska, Halina Car, Róża J. Wiśniewska, Konstanty Wiśniewski (p. 171) Abstract / Article (PDF format) Role of nitric oxide in anticonvulsant effects of benzodiazepines in mice. Sylwia Talarek, Sylwia Fidecka (p. 181) Abstract / Article (PDF format) Study on the influence of potent inhibitors of neuronal nitric oxide synthase on the antinociceptive and anticonvulsant activity of benzodiazepines in mice. Sylwia Fidecka (p. 193) Abstract / Article (PDF format) Influence of nifedipine, nitrendipine and verapamil at low concentration on antipyrine metabolism examined by extracorporeal rat liver perfusion. Adam Szeląg, Jan Magdalan, Maria Rutkowska, Wojciech Dziewiszek, Małgorzata Trocha, Małgorzata Rzepka, Małgorzata Pieśniewska, Lidia Fereniec (p. 203) Abstract / Article (PDF format) Intraperitoneal administration of salicylate dose-dependently prevents stress-induced ulcer formation in rats. Akçahan Gepdiremen, Halis Süleyman (p. 209) Abstract / Article (PDF format) Effects of amiloride and bumetanide on ion transport in the caecum of rabbit. Danuta I. Kosik-Bogacka, Bolesław Banach, Tomasz Tyrakowski, Alina Kozłowska, Sylwia Kozłowska (p. 213) Abstract / Article (PDF format) Effect of amiloride and bumetanide on ionic currents in the epithelium of caecum from starved rabbits. Danuta Kosik-Bogacka, Bolesław Banach, Tomasz Tyrakowski (p. 221) Abstract / Article (PDF format) Induction of caspase 3 and modulation of some apoptotic genes in human acute promyelocytic leukemia HL-60 cells by carboplatin with amifostine. Marek Mirowski, Marek Różalski, Urszula Krajewska, Ewa Balcerczak, Wojciech Młynarski, Ryszard Wierzbicki (p. 227) Abstract / Article (PDF format) Differential effect of betulin and betulinic acid on cytokine production in human whole blood cell cultures. Barbara Zdzisińska, Wojciech Rzeski, Roman Paduch, Agnieszka Szuster-Ciesielska, Józef Kaczor, Katarzyna Wejksza, Martyna Kandefer-Szerszeń (p. 235) Abstract / Article (PDF format) Comparison of the effects of azathioprine and its novel non-mercaptopurine analog on antibody response in rabbits. Saafan Al-Safi, Bassam Tashtoush, Mohamad Hassan (p. 239) Abstract / Article (PDF format) SHORT COMMUNICATIONS Pituitary adenylate cyclase-activating polypeptide (PACAP)-evoked increase in cyclic AMP production in chick cerebral cortex: lack of a role of the protein kinase C pathway. Jolanta B. Zawilska, Pawel Niewiadomski, Jerzy Z. Nowak (p. 245) Abstract / Article (PDF format) Metabolism of lidocaine by liver microsomes from streptozotocin-diabetic rats. Barbara Gawrońska-Szklarz, Dawid Musiał, Marek Droździk, Bartosz Paprota (p. 251) Abstract / Article (PDF format) PRELIMINARY COMMUNICATIONS Desensitization of H2-like histamine receptors stimulating cyclic AMP formation in the chick cerebral cortex. Paulina Sędkowska, Jolanta B. Zawilska, Jerzy Z. Nowak (p. 255) Abstract / Article (PDF format) Investigations of anti-inflammatory and analgesic activities of prednisolone solid dispersion prepared with skimmed milk. Nefise O. Sahin, Tadeusz Librowski (p. 261) Abstract / Article (PDF format) Abstracts of the TWELVTH DAYS of NEUROPSYCHOPHARMACOLOGY (p. 275) Lectures / Oral presentations (PDF format)

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Effects of adenosine receptor agonists and antagonists in amphetamine-induced conditioned place preference test in rats. Ewa Poleszak, Danuta Malec (p. 319) Abstract / Article (PDF format) Calcium channel antagonists suppress nicotine-induced place preference and locomotor sensitization in rodents. Grażyna Biała (p. 327) Abstract / Article (PDF format) Behavioral effects of D-AP7 in rats subjected to experimental hypoxia. Agnieszka Nadlewska, Halina Car, Róża Wiśniewska, Zdzisław Hoły, Konstanty Wiśniewski (p. 337) Abstract / Article (PDF format) Influence of NMDA, a potent agonist of glutamate receptors, on behavioral activity in 4-week streptozotocin-induced diabetic rats. Konstanty Wiśniewski, Małgorzata Fedosiewicz-Wasiluk, Zdzisław Z. Hoły, Halina Car, Emilia Grzęda (p. 345) Abstract / Article (PDF format) In vitro immunoregulatory effects of antidepressants in healthy volunteers. Agnieszka Szuster-Ciesielska, Anna Tustanowska-Stachura, Maria Słotwińska, Halina Marmurowska-Michałowska, Martyna Kandefer-Szerszeń (p. 353) Abstract / Article (PDF format) Influence of vigabatrin, a novel antiepileptic drug, on the anticonvulsant activity of conventional antiepileptics in pentetrazole-induced seizures in mice. Mariusz Świąder, Jarogniew Łuszczki, Marian Wielosz, Stanisław J. Czuczwar (p. 363) Abstract / Article (PDF format) Brain regional gamma-aminobutyric acid (GABA) and locomotor activity: effect of long-term aldrin exposure. Sk. Jamaluddin, Mrinal K. Poddar (p. 371) Abstract / Article (PDF format) Contribution of the histaminergic receptor subtypes to histamine-induced cerebellar granular neurotoxicity. Akcahan Gepdiremen, Mehmet E. Buyukokuroglu, Ahmet Hacimuftuoglu, Halis Suleyman (p. 383) Abstract / Article (PDF format) Antioxidant properties of newly synthesized N-propargylamine derivatives of nitroxyl: a comparison with deprenyl. Agata Kochman, Janusz Skolimowski, Lidia Gębicka, Diana Metodiewa (p. 389) Abstract / Article (PDF format) Influence of N-acetylcysteine on bioactivation of nitroglycerin to nitric oxide and S-nitrosothiols in the liver and brain of mice. Maria Sokołowska, Lidia Włodek (p. 401) Abstract / Article (PDF format) Influence of mianserin on the activity of some hypotensive drugs in spontaneously hypertensive rats. Dorota Górska, Dariusz Andrzejczak (p. 409) Abstract / Article (PDF format) Gender differences in effects of pinacidil but not diazoxide on heart automatism in the isolated guinea pig right atria. Ivan Kocić, Marta Gruchała, Jacek Petrusewicz (p. 419) Abstract / Article (PDF format) New treatment methods in verapamil poisoning: experimental studies. Jan Magdalan (p. 425) Abstract / Article (PDF format) Effects of doxycycline on development of changes in histomorphometric parameters of bones induced by bilateral ovariectomy in rats. Joanna Folwarczna, Maria Pytlik, Waldemar Janiec (p. 433) Abstract / Article (PDF format) SHORT COMMUNICATION Endogenous level of kynurenic acid and activities of kynurenine aminotransferases following transient global ischemia in the gerbil hippocampus. Elżzbieta Luchowska, Piotr Luchowski, Anna Sarnowska, Marian Wielosz, Waldemar A. Turski, Ewa M. Urbańska (p. 443) Abstract / Article (PDF format) PRELIMINARY COMMUNICATIONS Anxiolytic-like effects of preferential dopamine D3 receptor agonists in an animal model. Zofia Rogóż, Grażyna Skuza, Aleksandra Kłodzińska (p. 449) Abstract / Article (PDF format) Reduced potency of zinc to interact with NMDA receptors in hippocampal tissue of suicide victims. Gabriel Nowak, Bernadeta Szewczyk, Krystyna Sadlik, Wojciech Piekoszewski, Franciszek Trela, Ewa Florek, Andrzej Pilc (p. 455) Abstract / Article (PDF format) Central activity of new xanthone derivatives with chiral center in some pharmacological tests in mice. Magdalena Jastrzębska-Więsek, Tadeusz Librowski, Ryszard Czarnecki, Henryk Marona, Gabriel Nowak (p. 461) Abstract / Article (PDF format) Inflammation-induced alternations in local and central Met-enkephalin in mice. Magdalena Chadzinska, Anna Scislowska-Czarnecka, Krystyna Pierzchala-Koziec, Barbara Plytycz (p. 467) Abstract / Article (PDF format) Abstracts of Symposium THIRTY YEARS OF COOPERATION BETWEEN GERMAN AND POLISH PHARMACOLOGISTS. NEW PERSPECTIVES IN THE COMMON EUROPE (p. 479) (PDF Format)

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REVIEW - Progress in pharmacotherapy of thrombosis. Krzysztof Labuzek, Robert Krysiak, Bogusław Okopien, Zbigniew S. Herman (p. 523) Abstract / Article (PDF format) REVIEW - Is nitric oxide involved in the anticonvulsant action of antiepileptic drugs? Katarzyna Wojtal, Anna Gniatkowska-Nowakowska, Stanisław J. Czuczwar (p. 535) Abstract / Article (PDF format) Novel 4-alkyl-1-arylpiperazines and 1,2,3,4-tetrahydroisoquinolines containing diphenylmethylamino or diphenylmethoxy fragment with differentiated 5-HT1A/5-HT2A/D2 receptor activity. Maria H. Paluchowska, Maria J. Mokrosz , Sijka Charakchieva-Minol, Beata Duszyńska, Aneta Kozioł, Anna Wesołowska, Katarzyna Stachowicz, Ewa Chojnacka-Wójcik (p. 543) Abstract / Article (PDF format) Synthesis and 5-HT1A/5-HT2A receptor activity of new N-[3-(4-phenylpiperazin-1-yl)-propyl] derivatives of 3-spiro-cyclohexanepyrrolidine-2,5-dione and 3-spiro-beta-tetralonepyrrolidine-2,5-dione. Jolanta Obniska, Maciej Pawłowski, Marcin Kołaczkowski, Anna Czopek, Beata Duszyńska, Aleksandra Kłodzińska, Ewa Tatarczyńska, Ewa Chojnacka-Wójcik (p. 553) Abstract / Article (PDF format) Individual and combined effects of N6-cyclopentyladenosine, flunarizine and diazepam on aminophylline-induced recurrent generalized seizures in mice. Juliet Jaishree, Subramanyam Kumaresan, Suresh Sudha, Joy David, Chanda Kulkarni (p. 559) Abstract / Article (PDF format) Synthesis and anticonvulsant activities of 4-N-substituted arylsemicarbazones. Surendra N. Pandeya, Sonia Kohli, Nadeem Siddique, James P. Stables (p. 565) Abstract / Article (PDF format) Pharmacological evidence that methylene blue inhibits noradrenaline neuronal uptake in the rat vas deferens. Agnaldo B. Chies, Ricardo C. Custódio, Gregório L. de Souza, Fernando M.A. Corręa, Oduvaldo C.M. Pereira (p. 573) Abstract / Article (PDF format) Effect of the vascular endothelium on contractions induced by noradrenaline and phenylephrine in perforating branch of the human internal mammary artery. Srđan Pešić, Leposava Grbović, Aleksandar Jovanović, Miroslav Radenković, Dragica Stojić (p. 581) Abstract / Article (PDF format) Ethanol induced delayed cellular protection in mouse cardiac myocytes: role of inducible nitric oxide synthase. Mohammed A. Nayeem (p. 595) Abstract / Article (PDF format) Glycine modulates hepatic lipid accumulation in alcohol-induced liver injury. Rajagopal Senthilkumar, Periyasamy Viswanathan, Namasivayam Nalini (p. 603) Abstract / Article (PDF format) Evaluation of ofloxacin penetration into the skin after a single oral dose assessed by cutaneous microdialysis. Stanisława Bielecka-Grzela, Adam Klimowicz (p. 613) Abstract / Article (PDF format) Effect of experimental diabetes on pharmacokinetic parameters of lidocaine and MEGX in rats. Barbara Gawrońska-Szklarz, David H. Musiał, Andrzej Pawlik, Bartosz Paprota (p. 619) Abstract / Article (PDF format) Influence of tamoxifen on the mandible bone and hard teeth tissues of animals. Ewa Sobolewska, Bogumila Frączak, Janusz Kubrak, Joanna Ziółkowska, Iwona Noceń (p. 625) Abstract / Article (PDF format) Proximal tubule damage in patients treated with gentamicin or amikacin. Piotr Wiland, Jacek Szechiński (p. 631) Abstract / Article (PDF format) Gender differences in the pharmacokinetics of ethanol in saliva and blood after oral ingestion. Wojciech Gubała, Dariusz Zuba (p. 639) Abstract / Article (PDF format) SHORT COMMUNICATION Effect of nimesulide, rofecoxib and celecoxib on gastric tissue glutathione level in rats with indomethacin-induced gastric ulcerations. Konca Altinkaynak, Halis Süleyman, Fatih Akçay (p. 645) Abstract / Article (PDF format) PRELIMINARY COMMUNICATIONS Influence of some convulsant agents on the protective activity of a novel antiepileptic drug, felbamate, against maximal electroshock in mice. Mariusz Świąder, Maciej Gąsior, Marian Wielosz, Stanisław J. Czuczwar (p. 649) Abstract / Article (PDF format) Effects of cytochrome P-450 inducers on the perazine metabolism in a primary culture of human hepatocytes. Jacek Wójcikowski, Lydiane Pichard-Garcia, Patrick Maurel, Władysława A. Daniel (p. 655) Abstract / Article (PDF format) Comparative effect of physiological levels of leptin and insulin on cyclic AMP-induced stimulation of hepatic glycogen breakdown. Márcia Vardanega-Peicher, Rui Curi, Helenir M. Souza, Glaucia R. Borba-Murad, V.L.D. Siqueira, Sharize B. Galende, Roberto B. Bazotte (p. 659) Abstract / Article (PDF format)

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REVIEW - Role of glucocorticoids in the regulation of dopaminergic neurotransmission. Anna Czyrak, Marzena Maćkowiak, Agnieszka Chocyk, Katarzyna Fijał, Krzysztof Wędzony (p. 667) Abstract / Article (PDF format) REVIEW - Perspectives of losigamone in epilepsy treatment. Żaneta Kimber-Trojnar, Kinga K. Borowicz, Robert Małek, Grzegorz Sobieszek, Barbara Piskorska, Stanisław J. Czuczwar (p. 675) Abstract / Article (PDF format) REVIEW - Zonisamide: a new antiepileptic drug. Grzegorz Sobieszek, Kinga K. Borowicz, Żaneta Kimber-Trojnar, Robert Małek, Barbara Piskorska, Stanisław J. Czuczwar (p. 683) Abstract / Article (PDF format) REVIEW - Remacemide - a novel potential antiepileptic drug. Robert Małek, Kinga K. Borowicz, Żaneta Kimber-Trojnar, Grzegorz Sobieszek, Barbara Piskorska, Stanisław J. Czuczwar (p. 691) Abstract / Article (PDF format) MINIREVIEW - Anthocyanins in medicine. Edward Kowalczyk, Paweł Krzesiński, Marcin Kura, Bartosz Szmigiel, Jan Błaszczyk (p. 699) Abstract / Article (PDF format) A competitive antagonist of NMDA receptors CGP 40116 attenuates experimental symptoms of schizophrenia evoked by MK-801. Wojciech Zajączkowski, Anna Czyrak, Krzysztof Wędzony (p. 703) Abstract / Article (PDF format) Intravenous self-administration of morphine and cocaine: a comparative study. Paweł Mierzejewski, Eliza Koroś, Steven R. Goldberg, Wojciech Kostowski, Roman Stefański (p. 713) Abstract / Article (PDF format) Effect of some convulsants on the protective activity of loreclezole and its combinations with valproate or clonazepam in amygdala-kindled rats. Kinga K. Borowicz, Stanisław J. Czuczwar (p. 727) Abstract / Article (PDF format) Influence of SIB 1893, a selective mGluR5 receptor antagonist, on the anticonvulsant activity of conventional antiepileptic drugs in two models of experimental epilepsy. Kinga K. Borowicz, Barbara Piskorska, Jarogniew Łuszczki, Stanisław J. Czuczwar (p. 735) Abstract / Article (PDF format) Deficit of endogenous kynurenic acid in the frontal cortex of rats with a genetic form of absence epilepsy. Rafał M. Kamiński, Elżbieta Zielińska, Andrzej Dekundy, Gilles van Luijtelaar, Waldemar A. Turski (p. 741) Abstract / Article (PDF format) Cyclic AMP formation in chicken brain: effect of vasoactive intestinal peptide, peptide histidine-isoleucine (PHI), and some PHI-related peptides. Agnieszka Dejda, Izabela Matczak, Anna Wiktorowska-Owczarek, Jerzy Z. Nowak (p. 747) Abstract / Article (PDF format) Physiological antagonism of angiotensin II and lipopolysaccharides in early endotoxemia: pharmacometric analysis. Grzegorz Grześk, Leszek Szadujkis-Szadurski (p. 753) Abstract / Article (PDF format) Lipid profile in mice fed a high-fat diet after exogenous leptin administration. Jawaharbabu Kalaivanisailaja, Vaiyapuri Manju, Namasivayam Nalini (p. 763) Abstract / Article (PDF format) Cardiomyocyte mitochondrial KATP channels participate in the antiarrhythmic and antiinfarct effects of KATP activators during ischemia and reperfusion in an intact anesthetized rabbit model. Biswadeep Das, Chayna Sarkar (p. 771) Abstract / Article (PDF format) Glucose 6-phosphate dehydrogenase: in vitro and in vivo effects of dantrolene sodium. Şükrü Beydemir, Ilhami Gülçin, Ö. Irfan Küfrevioglu, Mehmet Çiftçi (p. 787) Abstract / Article (PDF format) Altered cytokeratin expression during chemoprevention of hamster buccal pouch carcinogenesis by S-allylcysteine. Seetharaman Balasenthil, Kunchala S. Rao, Siddavaram Nagini (p. 793) Abstract / Article (PDF format) SHORT COMMUNICATION Nicotine diminishes anticonvulsant activity of antiepileptic drugs in mice. Mirosław Czuczwar, Jacek Kiś, Piotr Czuczwar, Marian Wielosz, Waldemar Turski (p. 799) Abstract / Article (PDF format) PRELIMINARY COMMUNICATION Evaluation of interaction between gabapentin and baclofen in the formalin test in mice. Mirosław Czuczwar, Jacek Kiś, Jarogniew Łuszczki, Waldemar A. Turski, Krzysztof Przesmycki (p. 803) Abstract / Article (PDF format) Report on the German-Polish symposium "Thirty years of cooperation between German and Polish pharmacologists. New perspectives in the Common Europe", Białowieża, September 18-21, 2003. Barbara Malinowska, Manfred Göthert, Edmund Przegaliński, Eberhard Schlicker (p. 807) Article (PDF format) Neurochemical Conference MOLECULAR BASIS OF NEUROLOGICAL DISEASES AND NEW THERAPEUTIC STRATEGIES ABSTRACTS Oral presentations / Posters (PDF format) PAPERS: MSRV pol sequence copy number as a potential marker of multiple sclerosis. Mariola Zawada, Izabela Liweń, Monika Pernak, Danuta Januszkiewicz-Lewandowska, Karina Nowicka-Kujawska, Jolanta Rembowska, Krzysztof Lewandowski, Hanna Hertmanowska, Mieczysław Wender, Jerzy Nowak (p. 869) Abstract / Article (PDF format) Effect of immunomodulatory treatment of multiple sclerosis on lymphocyte surface immunomarkers. Grażyna Michałowska-Wender, Jacek Losy, Mieczysław Wender, Danuta Januszkiewicz-Lewandowska, Jerzy Nowak (p. 877) Abstract / Article (PDF format) Different vulnerability to cytotoxicity and susceptibility to protection of progenitors versus mature oligodendrocytes. Joanna Sypecka (p. 881) Abstract / Article (PDF format) Non-genomic effect of estradiol on plasma membrane calcium pump activity in vitro. Janusz Szemraj, Iwona Kawecka, Lilla Lachowicz, Ludmila Żylińska (p. 887) Abstract / Article (PDF format) Dual action of cyclin-dependent kinase inhibitors: induction of cell cycle arrest and apoptosis. A comparison of the effects exerted by roscovitine and cisplatin. Józefa Węsierska-Gądek, Marieta Gueorguieva, Marcel Horky (p. 895) Abstract / Article (PDF format) Cannabinoids alter recognition memory in rats. Piotr Kosiorek, Anna Hryniewicz, Izabela Bialuk, Agnieszka Zawadzka, Maria M. Winnicka (p. 903) Abstract / Article (PDF format) Apolipoprotein E4 and A(beta) peptide 1-42 inhibit polyphosphoinositide biosynthesis in rat brain cortex. Agata Zambrzycka, Maria Kacprzak (p. 911) Abstract / Article (PDF format) Transition metal ions significantly decrease phospholipase C activity degrading phosphatidylinositol-4,5-bisphosphate in the brain cortex. Agata Zambrzycka, Magdalena Cąkała, Monika Kamińska (p. 915) Abstract / Article (PDF format)

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REVIEW - Potential antidepressant activity of sigma ligands. Grażyna Skuza (p. 923) Abstract / Article (PDF format) REVIEW - Role of metabotropic glutamate receptors in animal models of Parkinson’s disease. Anna Senkowska, Krystyna Ossowska (p. 935) Abstract / Article (PDF format) Influence of acute and chronic 1,2,3,4-tetrahydroisoquinoline administration on the expression of proenkephalin mRNA in the rat striatum. Jadwiga Wardas, Małgorzata Zapała, Elżbieta Lorenc-Koci (p. 951) Abstract / Article (PDF format) Neonatal 5-hydroxytryptamine depletion induces depressive-like behavior in adult rats. Wojciech Kostowski, Paweł Krząścik (p. 957) Abstract / Article (PDF format) Effects of gabapentin and antidepressant drug combinations on convulsions and memory in mice. Ahsan N. Rizwan, Atif Ali, Yashomati Dua, Shanthi N. Pal, K.K. Pillai (p. 965) Abstract / Article (PDF format) Anxiolytic-like profile of propofol, a general anesthetic, in the plus-maze test in mice. Mehmet Kurt, S. Sirri Bilge, Osman Kukula, Suleyman Celik, Yuksel Kesim (p. 973) Abstract / Article (PDF format) Neuroprotective effect of NPY on kainate neurotoxicity in the hippocampus. Maria Śmiałowska, Joanna M. Wierońska, Bernadeta Szewczyk (p. 979) Abstract / Article (PDF format) Effect of L-arginine on memory in rats. Andrzej Plech, Tomasz Klimkiewicz, Beata Maksym (p. 987) Abstract / Article (PDF format) Effects of combined treatment with imipramine and metyrapone in the forced swimming test in rats. Behavioral and pharmacokinetic studies. Zofia Rogóż, Grażyna Skuza, Jacek Wójcikowski, Władysława A. Daniel (p. 993) Abstract / Article (PDF format) Effect of cyclooxygenase and NO synthase inhibitors administered centrally on antinociceptive action of acetaminophen (Part II). Magdalena Bujalska (p. 1001) Abstract / Article (PDF format) Synthesis, in vitro and in vivo 5-HT1A/5-HT2A serotonin receptor activity of new hybrid 1,2,3,4-tetrahydro-gamma-carbolines with 1-(2-methoxyphenyl)piperazine moiety. Jan Boksa, Sijka Charakchieva-Minol, Beata Duszyńska, Ryszard Bugno, Aleksandra Kłodzińska, Ewa Tatarczyńska, Ewa Chojnacka-Wójcik, Andrzej J. Bojarski (p. 1013) Abstract / Article (PDF format) Nitric oxide- and prostaglandin-mediated cardioprotection by bradykinin in myocardial ischemia and reperfusion injury. Krishna K. Veeravalli, Annapurna Akula, Murali K. Kota (p. 1021) Abstract / Article (PDF format) Evaluation of the antiperoxidative effects of melatonin in ammonium acetate-treated Wistar rats. Peter J. Lena, Perumal Subramanian (p. 1031) Abstract / Article (PDF format) Taurine prevents acrylonitrile-induced oxidative stress in rat brain. Karthikeyan Mahalakshmi, Gullapalli Pushpakiran, Carani V. Anuradha (p. 1037) Abstract / Article (PDF format) Effects of classic and newer antidepressants on the oxidation pathways of caffeine in rat liver. In vitro study. Władysława A. Daniel, Marta Kot, Jacek Wójcikowski (p. 1045) Abstract / Article (PDF format) Influence of classic and atypical neuroleptics on caffeine oxidation in rat liver microsomes. Władysława A. Daniel, Marta Kot, Jacek Wójcikowski (p. 1055) Abstract / Article (PDF format) Pharmacokinetics of liposomes designed to carry glucocorticoids. Rafal Hrynyk, Gert Storm, Bart Metselaar, Marek Langner (p. 1063) Abstract / Article (PDF format) Effect of neutral endopeptidase inhibition on vascular response induced by exogenous angiotensin I in the isolated rat lung. Joanna B. Bartuś, Stefan Chłopicki (p. 1071) Abstract / Article (PDF format) Influence of carnosine on the cardiotoxicity of doxorubicin in rabbits. 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Bülent Aktan, Seyithan Taysi, Kenan Gümüştekin, Harun Üçünçü, Ramazan Memişogullari, Kürşad Save, Nuri Bakan (p. 1105) Abstract / Article (PDF format) Synthesis of some new 2,5-disubstituted 1,3,4-thiadiazoles containing isomeric pyridyl as potent antimicrobial agents. Khosrow Zamani, Khalil Faghihi, Malek S. Mehranjani (p. 1111) Abstract / Article (PDF format) SHORT COMMUNICATIONS Involvement of CRF but not NPY in the anxiety regulation via NMDA receptors. Joanna M. Wierońska, Bernadeta Szewczyk, Agnieszka Pałucha, Piotr Brański, Maria Śmiałowska (p. 1119) Abstract / Article (PDF format) Blocking impact of clozapine on cocaine locomotor and sensitizing effects in rats. Małgorzata Filip, Iwona Papla, Ewa Nowak, Edmund Przegaliński (p. 1125) Abstract / Article (PDF format) Inhibitory effect of some neuroactive steroids on cocaine-induced kindling in mice. 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Grażyna Skuza, Zofia Rogóż (p. 1149) Abstract / Article (PDF format) Opposite effects of clozapine and sulpiride on the lipopolysaccharide-induced inhibition of the GR-mediated gene transcription in fibroblast cells. Agnieszka Basta-Kaim, Bogusława Budziszewska, Lucylla Jaworska-Feil, Monika Leśkiewicz, Magdalena Tetich, Marta Kubera, Simon Scharpe, Władysław Lasoń (p. 1153) Abstract / Article (PDF format) Early exposure to hypertonic solution strongly intensifies the effects of K+ channel opener, rilmakalim, in guinea pig ventricular myocytes. Ivan Kocić, Yuji Hirano, Masayasu Hiraoka (p. 1159) Abstract / Article (PDF format) Abstracts of Symposium AN INTRIGUING NATURE OF ESTROGENS (PDF format) (p. 1165)