CONTENTS (PDF format)

REVIEW - Third generation antiepileptic drugs: mechanisms of action, pharmacokinetics and interactions. Jarogniew J. Łuszczki (p. 197) Abstract / Article (PDF format) REVIEW - Rimonabant: an antagonist drug of the endocannabinoid system for the treatment of obesity. Carlos E. Leite, Clei A. Mocelin, Guilherme O. Petersen, Mirna B. Leal, Flavia V. Thiesen (p. 217) Abstract / Article (PDF format) REVIEW - Pharmacology of dimethyl sulfoxide in cardiac and CNS damage. Stanley W. Jacob, Jack C. de la Torre (p. 225) Abstract / Article (PDF format) Influence of bupropion and calcium channel antagonists on the nicotine-induced memory-related response of mice in the elevated plus maze. Grażyna Biała, Marta Kruk (p. 236) Abstract / Article (PDF format) Characterization of the anticonvulsant activity of doxepin in various experimental seizure models in mice. Xian-Yu Sun, Lei Zhang, Cheng-Xi Wei, Hu-Ri Piao, Zhe-Shan Quan (p. 245) Abstract / Article (PDF format) Influence of agmatine on the protective action of numerous antiepileptic drugs against pentetrazole-induced seizures in mice. Jarogniew J. Łuszczki, Remigiusz Czernecki, Monika Dudra-Jastrzębska, Kinga K. Borowicz, Stanisław J. Czuczwar (p. 252) Abstract / Article (PDF format) 5-HT-induced depression of the spinal monosynaptic reflex potential utilizes different types of 5-HT receptors depending on Mg2+ availability. Shripad B. Deshpande, Amar N. Maurya, Jitendra N. Singh (p. 261) Abstract / Article (PDF format) Lack of effect of naltrexone on the spinal synergism between morphine and non steroidal anti-inflammatory drugs. Hugo F. Miranda, Gianni Pinardi (p. 268) Abstract / Article (PDF format) Role of potassium channels in the relaxant effect of levosimendan in guinea pig tracheal preparations. Bilsen Eksert, Coşkun Usta (p. 275) Abstract / Article (PDF format) Il-1beta, IL-6, and TNF gene polymorphisms do not affect the treatment outcome of rheumatoid arthritis patients with leflunomide. Andrzej Pawlik, Magdalena Herczyńska, Mateusz Kurzawski, Krzysztof Safranow, Violetta Dziedziejko, Zygmunt Juzyszyn, Marek Droździk (p. 281) Abstract / Article (PDF format) Antitumor effects of a selenium heteropoly complex in K562 cells. Yang Jun-Ying, Xu Cun-Shuan (p. 288) Abstract / Article (PDF format) Antigenotoxic effect of genistein against 7,12-dimethylbenz[a]anthracene induced genotoxicity in bone marrow cells of female Wistar rats. Pachaiappan Pugalendhi, Shanmugam Manoharan, Kuppusamy Panjamurthy, Subramanian Balakrishnan, Madhavan R. Nirmal (p. 296) Abstract / Article (PDF format) Effects of the cannabinoid CB1 receptor antagonist AM 251 on the reinstatement of nicotine-conditioned place preference by drug priming in rats. Barbara Budzyńska, Marta Kruk, Grażyna Biała (p. 304) Abstract / Article (PDF format) SHORT COMMUNICATIONS Neonatal co-lesion by DSP-4 and 5,7-DHT produces adulthood behavioral sensitization to dopamine D2 receptor agonists. Przemysław Nowak, Dariusz Nitka, Adam Kwieciński, Jadwiga Jośko, Jacek Drab, Dorota Pojda-Wilczek, Jacek Kasperski, Richard M. Kostrzewa, Ryszard Brus (p. 311) Abstract / Article (PDF format) Investigation of the acute effect of leptin on the inhibition of glycogen catabolism by insulin in rat liver perfused in situ. Erica G. Mario, Eledir S. Leonardo, Bruna K. Bassoli, Priscila Cassolla, Glaucia R. Borba-Murad, Roberto B. Bazotte, Helenir M. de Souza (p. 319) Abstract / Article (PDF format) Use of transgenic (knockout) mice reveals a site distinct from the alpha2A-adrenoceptors for agmatine in the vas deferens. Wilson C. Santos, Lucia Garcez-do-Carmo, Eliane C. da Silva, Ricardo de Pascual, Neide H. Jurkiewicz, Aron Jurkiewicz, Luis Gandía (p. 325) Abstract / Article (PDF format) Contribution of NO, ATP-sensitive K+ channels and protaglandins to adenosine receptor agonists-induced relaxation of the rat tail artery. Katarzyna Kędzior, Renata Szczepańska, Ivan Kocić (p. 330) Abstract / Article (PDF format) Acute doxorubicin pulmotoxicity in rats with malignant neoplasm is effectively treated with fullenerol C60(OH)24 through inhibition of oxidative stress. Rade Injac, Natasa Radic, Biljana Govedarica, Martina Perse, Anton Cerar, Aleksandar Djordjevic, Borut Strukelj (p. 335) Abstract / Article (PDF format) 4-Thio-uridylate (UD29) interferes with the function of protein -SH and inhibits HIV replication in vitro. Zoltán Beck, Andrea Kis, Erika Berényi, Péter Kovács, László Fésüs, János Aradi (p. 343) Abstract / Article (PDF format) Abstracts of THE EIGHTEENTH DAYS OF NEUROPSYCHOPHARMACOLOGY Oral communications (p. 351) Posters (p. 369)

CONTENTS (PDF format)

REVIEW - Physiology and pharmacology of melatonin in relation to biological rhythms. Jolanta B. Zawilska, Debra J. Skene, Josephine Arendt (p. 383) Abstract / Article (PDF format) REVIEW - Atherosclerotic risk among children taking antiepileptic drugs. Tomasz Jakubus, Małgorzata Michalska-Jakubus, Krzysztof Łukawski, Agnieszka Janowska, Stanisław J. Czuczwar (p. 411) Abstract / Article (PDF format) Stress-opioid interactions: a comparison of morphine and methadone. Ewa Taracha, Paweł Mierzejewski, Małgorzata Lehner, Stanisław J. Chrapusta, Maria Kała, Wojciech Lechowicz, Adam Hamed, Anna Skórzewska, Wojciech Kostowski, Adam Płaźnik (p. 424) Abstract / Article (PDF format) Lipid peroxidation and antioxidant protection in patients during acute depressive episodes and in remission after fluoxetine treatment. Piotr Gałecki, Janusz Szemraj, Małgorzata Bieńkiewicz, Antoni Florkowski, Elżbieta Gałecka (p. 436) Abstract / Article (PDF format) No association of three GRIN2B polymorphisms with lithium response in bipolar patients. Aleksandra Szczepankiewicz, Maria Skibińska, Aleksandra Suwalska, Joanna Hauser, Janusz K. Rybakowski (p. 448) Abstract / Article (PDF format) Effect of fluoxetine on tolerance to the analgesic effect of morphine in mice with skin cancer. Alireza Mohajjel Nayebi, Hassan Rezazadeh, Yousef Parsa (p. 453) Abstract / Article (PDF format) Synergistic interaction of gabapentin with tiagabine in the hot-plate test in mice: an isobolographic analysis. Jarogniew J. Łuszczki, Agnieszka Kołacz, Ewa Wojda, Mirosław Czuczwar, Krzysztof Przesmycki, Stanisław J. Czuczwar (p. 459) Abstract / Article (PDF format) Blocking angiogenesis with peptides that inhibit the activity of procollagen C-endopeptidase. Marta Lesiak, Aleksandra Auguściak-Duma, Anna Szydło, Aleksander L. Sieroń (p. 468) Abstract / Article (PDF format) Structure, stability, and antiplatelet activity of O-acyl derivatives of salicylic acid and lipophilic esters of acethylsalicylate. Ilya B. Zavodnik, Elena Lapshina, Elena Sudnikovich, Magdalena Boncler, Bogusława Luzak, Marcin Różalski, Magdalena Helińska, Cezary Watała (p. 476) Abstract / Article (PDF format) Enhanced oxidative stress in hypertrophic cardiomyopathy. Paweł P. Dimitrow, Anetta Undas, Paweł Wołkow, Wiesława Tracz, Jacek S. Dubiel (p. 491) Abstract / Article (PDF format) CCN2 protein is an announcing marker for cardiac remodeling following STZ-induced moderate hyperglycemia in mice. Karol A. Kamiński, Barbara Szepietowska, Tomasz Bonda, Marcin Kożuch, Joanna Mencel, Andrzej Małkowski, Krzysztof Sobolewski, Oksana Kovalchuk, Lech Chyczewski, Małgorzata Szelachowska, Maria Górska, Włodzimierz J. Musiał, Maria M. Winnicka (p. 496) Abstract / Article (PDF format) Effect of interleukin 6 deficiency on the expression of Bci-2 and Bax in the murine heart. Karol A. Kamiński, Marcin Kożuch, Tomasz A. Bonda, Maria M. Stepaniuk, Ewa Waszkiewicz, Lech Chyczewski, Włodzimierz J. Musiał, Maria M. Winnicka (p. 504) Abstract / Article (PDF format) Reason for the aggravation of diseases caused by inflammation and the ineffectiveness of NSAIDs on these diseases in rainy weather. Halis Suleyman, Elif Cadirci, Abdulmecit Albayrak, Zekai Halici, Beyzagul Polat, Ahmet Hacimuftuoglu, Hamit H. Alp (p. 514) Abstract / Article (PDF format) Altered response of human umbilical artery to 5-HT in gestational diabetic pregnancy. Miroslav Radenković, Nebojša Radunović, Paja Momčilov, Leposava Grbović (p. 520) Abstract / Article (PDF format) Thalidomide affects the skeletal system of ovariectomized rats. Ilona Kaczmarczyk-Sedlak, Joanna Folwarczna, Henryk L. Trzeciak (p. 529) Abstract / Article (PDF format) Role of TLR ligands in epicutaneously induced contrasupression. Monika Majewska, Krzysztof Bryniarski, Maria Ptak, Katarzyna Zając, Magdalena Zemelka, Francis M. Lobo, Włodzimierz Ptak, Marian Szczepanik (p. 539) Abstract / Article (PDF format) Influence of cyclophosphamide and its metabolic products on the activity of peritoneal macrophages in mice. Krzysztof Bryniarski, Marian Szczepanik, Maria Ptak, Magdalena Zemelka, Włodzimierz Ptak (p. 550) Abstract / Article (PDF format) SHORT COMMUNICATIONS Effect of prenatal manganese intoxication on [3H]glucose uptake in the brain of rats lesioned as neonates with 6-hydroxydopamine. Adam Kwieciński (p. 558) Abstract / Article (PDF format) Effects of androsterone on convulsions in various seizure models in mice. Katarzyna Mróz, Tomasz Mróz, Marian Wielosz, Piotr Tutka (p. 564) Abstract / Article (PDF format) Abstracts of THE FIRST CONFERENCE ON PROGRESS IN EPILEPSY AND ANTIEPILEPTIC DRUGS PDF format Erratum for: Pharmacol. Rep., 2007, 59, no. 5 (p. 490) PDF format

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OBITUARY - Professor Sławomir S. Rump, M.D., D.Sc. Physician, pharmacologist, toxicologist, scientific advisor (1929-2009). Marek Kowalczyk (p. 593) Article (PDF format) REVIEW - Role of the NF-kappaB in the pathogenesis of diabetes and its associated complications. Sandip Patel, Dev Santani (p. 595) Abstract / Article (PDF format) Serum cortisol concentration in patients with major depression after treatment with clomipramine. Jadwiga Piwowarska, Małgorzata Wrzosek, Maria Radziwoń-Zaleska, Beata Ryszewska-Pokraśniewicz, Michał Skalski, Halina Matsumoto, Agata Biernacka-Bazyluk, Waldemar Szelenberger, Jan Pachecka (p. 604) Abstract / Article (PDF format) Prenatal stress decreases glycogen synthase kinase-3 phosphorylation in the rat frontal cortex. Magdalena Szymańska, Anna Suska, Bogusława Budziszewska, Lucylla Jaworska-Feil, Agnieszka Basta-Kaim, Monika Leśkiewicz, Marta Kubera, Aleksandra Gergont, Sławomir Kroczka, Marek Kaciński, Władysław Lasoń (p. 612) Abstract / Article (PDF format) 2-Methyl-6-phenylethynyl-pyridine (MPEP), a non-competitive mGluR5 antagonist, differentially affects the anticonvulsant activity of four conventional antiepileptic drugs against amygdala-kindled seizures in rats. Kinga K. Borowicz, Jarogniew J. Łuszczki, Stanisław J. Czuczwar (p. 621) Abstract / Article (PDF format) Bradykinin receptor antagonists and cyclooxygenase inhibitors in vincristine- and streptozotocin-induced hyperaslgesia. Magdalena Bujalska, Helena Makulska-Nowak (p. 631) Abstract / Article (PDF format) Optimization of lidocaine application in tumescent local anesthesia. Krystyna Głowacka, Krystyna Orzechowaska-Juzwenko, Andrzej Bieniek, Anna Wiela-Hojeńska, Magdalena Hurkacz (p. 641) Abstract / Article (PDF format) Effect of HMG-CoA (3-hydroxy-3-methyl-glutaryl-CoA) reductase inhibitors on the concentration of insulin-like growth factor-1 (IGF-1) in hypercholesterolemic patients. Janusz Szkodziński, Wojciech Romanowski, Bartosz Hudzik, Andrzej Kaszuba, Ewa Nowakowska-Zajdel, Ryszard Szkilnik, Barbara Pietrasińska, Barbara Zubelewicz-Szkodzińska (p. 654) Abstract / Article (PDF format) Beneficial effects of L-arginine against diabetes-induced oxidative stress in gastrointestinal tissues in rats. Nitin I. Kochar, Sudhir N. Umathe (p. 665) Abstract / Article (PDF format) Accelerated thrombus lysis in the blood of plasminogen activator inhibitor deficient mice is inhbited by PAI-1 with a very long half-life. Jerzy Jankun, Ansari M. Aleem, Radosław Struniawski, Wiesława Łysiak-Szydłowska, Steven H. Selman, Ewa Skrzypczak-Jankun (p. 673) Abstract / Article (PDF format) Effects of taurine on contractions of the porcine coronary artery. Yu Liu, Longgang Niu, Wenjing Zhan, Lijuan Cui, Xuanping Zhang, Yueqin Liang, Mingsheng Zhang (p. 681) Abstract / Article (PDF format) Association of the MDR1 (ABCB1) gene 3435C>T polymorphism with male infertility. Marek Droździk, Joanna Stefankiewicz, Rafał Kurzawa, Wanda Górnik, Tomasz Bączkowski, Mateusz Kurzawski (p. 690) Abstract / Article (PDF format) Effects of escin on acute inflammation and the immune system in mice. Tian Wang, Fenghua Fu, Leiming Zhang, Bin Han, Mei Zhu, Xiumei Zhang (p. 697) Abstract / Article (PDF format) Endogenous steroids are responsible for lactoferrin-induced myelopoiesis in mice. Michał Zimecki, Jolanta Artym, Maja Kocięba (p. 705) Abstract / Article (PDF format) Fluoroquinolones lower constitutive H2AX and ATM phosphorylation in TK6 lymphoblastoid cells via modulation of the intracellular redox status. H. Dorota Halicka, Daniel J. Smart, Frank Traganos, Gary M. Williams, Zbigniew Darzynkiewicz (p. 711) Abstract / Article (PDF format) Circadian time-dependent chemopreventive potential of withaferin-A in 7,12-dimethyl-benz[a]anthracene-induced oral carcinogenesis. Shanmugam Manoharan, Kuppusamy Panjamurthy, Subramanian Balakrishnan, Kalaiarasan Vasudevan, Lakshmanan Vellaichamy (p. 719) Abstract / Article (PDF format) SHORT COMMUNICATIONS Synthesis and pharmacological properties of a new fluorescent opioid peptide analog. Monika Lukowiak, Piotr Kosson, Wim E. Hennink, Andrzej W. Lipkowski (p. 727) Abstract / Article (PDF format) Influence of orphenadrine upon the protective activity of various antiepileptics in the maximal electroshock-induced convulsions in mice. Mirosław Czuczwar, Jacek Cięszczyk, Katarzyna Czuczwar, Jacek Kiś, Tomasz Saran, Waldemar A. Turski (p. 732) Abstract / Article (PDF format) Characterization of acute adverse-effect profiles of selected antiepileptic drugs in the grip-strength test in mice. Anna Zadrożniak, Ewa Wojda, Aleksandra Wlaź, Jarogniew J. Łuszczki (p. 737) Abstract / Article (PDF format) Neuroprotective effect of N-acetylcysteine in neurons exposed to arachidonic acid during simulated ischemia in vitro. Natalia Pawlas, Andrzej Małecki (p. 743) Abstract / Article (PDF format) Kynurenic acid protects against the homocysteine-induced impairment of endothelial cells. Katarzyna Wejksza, Wojciech Rzeski, Waldemar A. Turski (p. 751) Abstract / Article (PDF format)

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REVIEW - Overview on 5-HT receptors and their role in physiology and pathology of the central nervous system. Małgorzata Filip, Michael Bader (p. 761) Abstract / Article (PDF format) REVIEW - Inhibitors of type 2 sodium glucose cotransporters - a new strategy for diabetes treatment. Aleksandra Bołdys, Bogusław Okopień (p. 778) Abstract / Article (PDF format) Characterization of the naturally occuring Arg344His variant of the human 5-HT3A receptor. Sandra Combrink, Arevat Kostanian, Jutta Walstab, Martin Barann, Michael Brüss, Manfred Göthert, Heinz Bönisch (p. 785) Abstract / Article (PDF format) Treatment with 1,2,3,4,-tetrahydroisoquinoline affects glutamate release in the striatum but not the binding of [3H]MK-801 to NMDA receptors in the dopaminergic structures of the rat brain. Elżbieta Lorenc-Koci, Krystyna Gołembiowska, Małgorzata Pietraszek, Jadwiga Wardas (p. 798) Abstract / Article (PDF format) Analgesic activity of 3-mono-substituted derivatives of dihydrofuran-2-one in experimental rodent models of pain. Kinga Sałat, Barbara Filipek, Krzysztof Więckowski, Barbara Malawska (p. 807) Abstract / Article (PDF format) Effect of caffeine on the anticonvulsant effects of oxcarbazepine, lamotrigine and tiagabine in a mouse model of generalized tonic-clonic seizures. Magdalena Chrościńska-Krawczyk, Neville Ratnaraj, Philip N. Patsalos, Stanisław J. Czuczwar (p. 819) Abstract / Article (PDF format) Anti-apoptotic effect of memantine against staurosporine- and low-potassium-induced cell death in cerebellar granule cells: a development-dependent effect. Danuta Jantas, Władysław Lasoń (p. 827) Abstract / Article (PDF format) Commonly used ryanodine receptor activator, 4-chloro-m-cresol (4CmC), is also an inhibitor of SERCA Ca2+ pumps. Fawaz Al-Mousa, Francesco Michelangeli (p. 838) Abstract / Article (PDF format) Influence of ABCB1 gene polymorphisms on the pharmacokinetics of azithromycin among healthy Chinese Han ethnic subjects. Xiao-Jing He, Li-Mei Zhao, Feng Qiu, Ya-Xin Sun, Jesse Li-Ling (p. 843) Abstract / Article (PDF format) Perazine at therapeutic drug concentrations inhibits human cytochrome P450 isoenzyme 1A2 (CYP1A2) and caffeine metabolism - an in vitro study. Jacek Wójcikowski, Władysława A. Daniel (p. 851) Abstract / Article (PDF format) Effects of ischemia-reperfusion and pretreatment with mildronate on rat liver mitochondrial function. Sonata Trumbeckaite, Marius Kinčius, Andrius Preidis, Monika Preidiene, Vincentas Veikutis, Vilmante Borutaite, Antanas Gulbinas (p. 859) Abstract / Article (PDF format) Chronic ß-adrenergic activation-induced left ventricular systolic dysfunction is associated with systemic release of TNF-alpha and IL-1-ß in rats. Santosh Kumar, Sandeep Seth, Amardeep Jaiswal, Rajesh Enjamoori, Amit K. Dinda, Ruma Ray, Subir K. Maulik (p. 870) Abstract / Article (PDF format) Enhancement of fibrynolysis by gel-filtered platelets and its quenching by cytochalasin B and GPIIb/IIIa antagonists. Satoru Hoki, Yuko Suzuki, Kazuo Umemura, Tetsumei Urano (p. 877) Abstract / Article (PDF format) Possible new organoselenium supplement - evaluation of its influence on the kidneys in comparison with inorganic sodium selenite. Irena Musik, Anna Hordyjewska, Anna Boguszewska-Czubara, Kazimierz Pasternak (p. 885) Abstract / Article (PDF format) Effect of atorvastatin on paraoxonase1 (PON1) and oxidative status. Amar Nagila, Thinnakorn Permpongpaiboon, Soontharee Tantrarongroj, Pomwalee Porapakkham, Kultira Chinwattana, Sara Deakin, Sureerut Porntadavity (p. 892) Abstract / Article (PDF format) Antihyperglycemic effects of ASP8497 in streptozotocin-nicotinamide induced diabetic rats: comparison with other dipeptidyl peptidase-IV inhibitors. Atsuo Tahara, Akiko Matsuyama-Yokono, Ryosuke Nakano, Yuka Someya, Masahiko Hayakawa, Masayuki Shibasaki (p. 899) Abstract / Article (PDF format) Effects of high-fat mixed-lipid diet and exercise on the antioxidant system in skeletal and cardiac muscles of rats with colon carcinoma. Martina Perše, Rade Injac, Borut Štrukelj, Anton Cerar (p. 909) Abstract / Article (PDF format) Erythropoietin inhibits liver gelatinases during galactosamine-induced hepatic damage in rats. Agnieszka Mądro, Jacek Kurzepa, Grażyna Czechowska, Maria Słomka, Krzysztof Celiński, Stanisława Szymonik-Lesiuk (p. 917) Abstract / Article (PDF format) SHORT COMMUNICATIONS Effect of repeated co-treatment with fluoxetine and amantadine on the behavioral reactivity of the central dopamine and serotonin system in rats. Zofia Rogóż, Grażyna Skuza (p. 924) Abstract / Article (PDF format) Lack of effect of sildenafil on cocaine-induced convulsions in mice. Dorota Nieoczym, Katarzyna Socała, Piotr Wlaź (p. 930) Abstract / Article (PDF format) Effect of pregnancy and tobacco smoke on the antioxidant activity of rutin in an animal model. Ewa Florek, Ewa Ignatowicz, Wojciech Piekoszewski (p. 935) Abstract / Article (PDF format) Effects of N-acetylcysteine and ebselen on arachidonic acid release from astrocytes and neurons cultured in normoxic or stimulated ischemic conditions. Natalia Pawlas, Katarzyna Nierwińska, Anna Stolecka, Bożena Gabryel, Anna Pudełko, Andrzej Małecki (p. 941) Abstract / Article (PDF format) Frequency of common CYP3A5 gene variants in healthy Polish newborn infants. Grażyna Adler, Beata Łoniewska, Miłosz Parczewski, Agnieszka Kordek, Andrzej Ciechanowicz (p. 947) Abstract / Article (PDF format) Erratum for: Pharmacol. Rep., 2009, 61, no. 4 (p. 952) PDF format

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REVIEW - Nicotine dependence - human and animal studies, current pharmacotherapies and future perspectives. Magdalena Zaniewska, Edmund Przegaliński, Małgorzata Filip (p. 957) Abstract / Article (PDF format) REVIEW - Metamphetamine-induced neurotoxicity: the road to Parkinson's disease. Bessy Thrash, Kariharan Thiruchelvan, Manuj Ahuja, Vishnu Suppiramaniam, Muralikrishnan Dhanasekaran (p. 966) Abstract / Article (PDF format) REVIEW - Tramadol as an analgesic for mild to moderate cancer pain. Wojciech Leppert (p. 978) Abstract / Article (PDF format) REVIEW - Polymer-based non-viral gene delivery as a concept for the treatment of cancer. Anna Halama, Michał Kuliński, Tadeusz Librowski, Stanisław Lochyński (p. 993) Abstract / Article (PDF format) Cannabinoid CB1 receptors in rat medial prefrontal cortex are colocalized with calbindin- but not parvalbumin- and calretinin-positive GABA-ergic neurons. Krzysztof Wędzony, Agnieszka Chocyk (p. 1000) Abstract / Article (PDF format) ERK signalling pathway is not involved in PSA-NCAM-dependent alterations of hippocampal plasticity evoked by CB1 receptor activation. Marzena Maćkowiak, Dorota Dudys, Krzysztof Wędzony (p. 1008) Abstract / Article (PDF format) Influences of chronic venlafaxine, olanzapine and nicotine on the hippocampal and cortical concentrations of brain-derived neurotrophic factor (BDNF). Anna Czubak, Elżbieta Nowakowska, Krzysztof Kus, Kinga Burda, Jana Metelska, Wande Baer-Dubowska, Michał Cichocki (p. 1017) Abstract / Article (PDF format) Role of silent polymorphisms within the dopamine D1 receptor associated with schizophrenia on D1-D2 receptor hetero-dimerization. Katarzyna Grymek, Sylwia Lukasiewicz, Agata Faron-Górecka, Magdalena Tworzydlo, Agnieszka Polit, Marta Dziedzicka-Wasylewska (p. 1024) Abstract / Article (PDF format) Impact of postnatal dexamethasone on psychotomimetic effect of MK-801 measured on adult rats. Krzysztof Wędzony, Katarzyna Markowicz-Kula, Agnieszka Chocyk, Katarzyna Fijał, Aleksandra Przyborowska, Marzena Maćkowiak (p. 1034) Abstract / Article (PDF format) Effects of GABAB receptor agonists on cocaine hyperlocomotor and sensitizing effects in rats. Małgorzata Frankowska, Ewa Nowak, Małgorzata Filip (p. 1042) Abstract / Article (PDF format) Effect of co-administration of fluoxetine and amantadine on immunoendocrine parameters in rats subjected to a forced swimming test. Zofia Rogóż, Marta Kubera, Katarzyna Rogóż, Agnieszka Basta-Kaim, Bogusława Budziszewska (p. 1050) Abstract / Article (PDF format) Gestational manganese intoxication and anxiolytic-like effects of diazepam and the 5-HT1A receptor agonist 8-OH-DPAT in male Wistar rats. Adam Kwieciński, Przemysław Nowak (p. 1061) Abstract / Article (PDF format) Concomitant administration of fluoxetine and amantadine modulates the activity of peritoneal macrophages of rats subjected to a forced swimming test. Adam Roman, Zofia Rogóż, Marta Kubera, Dominika Nawrat, Irena Nalepa (p. 1069) Abstract / Article (PDF format) Effect of N-methyl-D-aspartate (NMDA) receptor antagonists on alpha-synuclein-evoked neuronal nitric oxide synthase activation in the rat brain. Agata Adamczyk, Grzegorz A. Czapski, Anna Kaźmierczak, Joanna B. Strosznajder (p. 1078) Abstract / Article (PDF format) Peripheral antinociceptive effects of MC4 receptor antagonists in a rat model of neuropathic pain - a biochemical and behavioural study. Katarzyna Starowicz, Shaaban A. Mousa, Ilona Obara, Agnieszka Chocyk, Ryszard Przewłocki, Krzysztof Wędzony, Halina Machelska, Barbara Przewłocka (p. 1086) Abstract / Article (PDF format) Magnesium ions and opioid agonists in vincristine-induced neuropathy. Magdalena Bujalska, Helena Makulska-Nowak, Stanisław W. Gumułka (p. 1096) Abstract / Article (PDF format) Inhibitory effects of amantadine on the production of pro-inflammatory cytokines by stimulated in vitro human blood. Marta Kubera, Michael Maes, Bogusława Budziszewska, Agnieszka Basta-Kaim, Monika Leśkiewicz, Beata Grygier, Zofia Rogóż, Władysław Lasoń (p. 1105) Abstract / Article (PDF format) Age-dependent stimulatory effect of desipramine and fluoxetine pretreatment on metastasis formation by B16F10 melanoma in male C57BL/6 mice. Marta Kubera, Beata Grygier, Beatriz Arteta, Krystyna Urbanska, Agnieszka Basta-Kaim, Bogusława Budziszewska, Monika Leśkiewicz, Elzbieta Kolaczkowska, Michael Maes, Marian Szczepanik, Monika Majewska, Wladyslaw Lason (p. 1113) Abstract / Article (PDF format) m-Trifluoromethyl-diphenyl diselenide attentuates pentylenetetrazole-induced seizures in mice by inhibiting GABA uptake in cerebral cortex slices. Marina Prigol, César A. Brüning, Benhur Godoi, Cristina W. Nogueira, Gilson Zeni (p. 1127) Abstract / Article (PDF format) Effect of atorvastatin and fenofibric acid on adipokine release from visceral and subcutaneous adipose tissue of patients with mixed dyslipidemia and normolipidemic subjects. Robert Krysiak, Krzysztof Łabuzek, Bogusław Okopień (p. 1134) Abstract / Article (PDF format) Sildenafil increases the force of right atrial contractions in vitro via the NO-guanylyl cyclase pathway involving ß-adrenoceptor linked mechanisms. Sadhana Kanoo, Shripad B. Deshpande (p. 1146) Abstract / Article (PDF format) Tumor anti-initiating activity of some novel 3,4-dihydropyrimidinones. Hanaa A. Tawfik, Fatma Bassyouni, Amira M. Gamal-Eldeen, Mona A. Abo-Zeid, Wageeh S. El-Hamouly (p. 1153) Abstract / Article (PDF format) Study of the cytotoxicity and antioxidant capacity of N/OFQ(1-13)NH2 and its structural analogues. Margarita Kirkova, Rositsa Zamfirova, Monika Leśkiewicz, Marta Kubera, Władysław Lasoń, Simeon Todorov (p. 1163) Abstract / Article (PDF format) SHORT COMMUNICATIONS Potentiation of the antidepressant-like effect of desipramine or reboxetine by metyrapone in the forced swimming test in rats. Zofia Rogóż (p. 1173) Abstract / Article (PDF format) Antidepressant-like effect of PRE-084, a selective sigma1 receptor agonist, in Albino Swiss and C57BL/6J mice. Grażyna Skuza, Zofia Rogóż (p. 1179) Abstract / Article (PDF format) Zinc-induced adaptive changes in NMDA/glutamatergic and serotonergic receptors. 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