Copyright © 1999 by Institute of Pharmacology
Polish Academy of Sciences 		Pol. J. Pharmacol., 1999, 51, 167-172
ISSN 1230-6002
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ROLE OF CALCIUM IONS IN VERTEBRATE PHOTOTRANSDUCTION
 Wojciech A. Gorczyca
 Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, PL 53-114 Wroc³aw, Poland

Role of calcium ions in vertebrate phototransduction. W.A. GORCZYCA. Pol. J. Pharmacol., 1999, 51, 167-172.

In the recent years several new regulatory calcium-binding proteins were identified in vertebrate photoreceptor cells. Calcium ions can regulate different stages of visual transduction acting through calcium-binding proteins. It is also accepted that Ca2+-mediated feedback pathways underlie the light adaptation mechanisms in photoreceptor cells. This article describes the role of calcium ions in the cascade of enzymatic reactions contributing to the vertebrate rod cell phototransduction and to light adaptation.

Key words: calcium ions, phototransduction, signal transduction, calcium-binding proteins, rod cells
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