Copyright © 1999 by Institute of Pharmacology
Polish Academy of Sciences
Pol. J. Pharmacol., 1999, 51, 113-117
ISSN 1230-6002

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MINIREVIEW
TRANSCELLULAR BIOSYNTHESIS OF EICOSANOIDS1
Ryszard J. Gryglewski
Department of Pharmacology, Medical College, Jagiellonian University, Grzegórzecka 16, PL 31-531 Kraków, Poland

Transcellular biosynthesis of eicosanoids. R.J. GRYGLEWSKI. Pol. J. Pharmacol., 1999, 51, 113-117.

Transcellular biosynthesis of prostacyclin (platelets/endothelial cells), cysteinyl-leukotrienes (granulocytes/endothelial cells) or lipoxins (granulocytes/renal cells) constitute a new approach to the therapy of thrombosis, ischaemic heart disease and glomerulonephritis.

Key words: eicosanoids, transcellular biosynthesis, thrombosis, coronary disease, aspirin-induced asthma, glomerulonephritis

  1 Plenary lecture presented during XIII Congress of the Polish Pharmacological Society, September 1998
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