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Copyright © 1998 by Institute of Pharmacology Polish Academy of Sciences

Pol. J. Pharmacol., 1998, 50, 453-456 ISSN 1230-6002

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PRELIMINARY COMMUNICATION
MECHANICAL REACTIVITY OF ISOLATED HUMAN AND GUINEA-PIG PORTAL VEINS TO SPASMOGENS
Kohsuke Uchida^1#, Atsushi Sakuma², Hiroaki Kogure², Yasuo Ohno³, Yuichiro Kamikawa¹
Departments of ¹ Pharmacology and ² Surgery II, Dokkyo University School of Medicine, Mibu, Tochigi 321-0293, Japan,
³ Division of Pharmacology, National Institute of Hygienic Sciences, Setagaya, Tokyo 158-0098, Japan

Mechanical reactivity of isolated human and guinea-pig portal veins to spasmogens. K. UCHIDA, A. SAKUMA, H. KOGURE, Y. OHNO, Y. KAMIKAWA. Pol. J. Pharmacol., 1998, 50, 453-456. The pattern of mechanical reactivity to prostaglandin F2alpha and endothelin-1 was different in circular muscle preparations of the extra-hepatic portal vein of humans and guinea-pigs. Key words: human, guinea-pig, isolated portal vein, circular smooth muscle, alfa-receptor, prostaglandin F2alfa, endothelin-1

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