Copyright © 1999 by Institute of Pharmacology
Polish Academy of Sciences 		Pol. J. Pharmacol., 1999, 51, 253-256
ISSN 1230-6002
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SHORT COMMUNICATION
 ANALGESIC ACTIVITY OF THIOUREIDO DERIVATIVES OF ARYLSEMICARBAZONES
 Vibha Mishraa, Surendra N. Pandeyab#, Paras N. Singhb, Dinesh C. Rupainwara
 a Department of Applied Chemistry, b Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi - 221 005, India

Analgesic activity of thioureido derivatives of arylsemicarbazones. V. MISHRA, S.N. PANDEYA, P.N. SINGH, D.C. RUPAINWAR. Pol. J. Pharmacol., 1999, 51, 253-256.

The synthesis of a series of novel arylsemicarbazones derived from 4-aminoacetophe-none and their evaluation for analgesic activity are described. The p-chloro-substituted derivatives (12-15) are extremely potent compounds as compared to standard drugs currently being used.

Key words: thioureido, semicarbazones, analgesic activity
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