CONTENTS (PDF format)

REVIEW - Huntington’s disease: pathogenesis to animal models. Puneet Kumar, Harikesh Kalonia, Anil Kumar (p. 1) Abstract / Article (PDF format) REVIEW - Liver X receptor (LXR) and the reproductive system - a potential novel target for therapeutic intervention. Jerzy Bełtowski, Andrzej Semczuk (p. 15) Abstract / Article (PDF format) MINIREVIEW - Role of endothelin-1 receptor blockers on hemodynamic parameters and oxidative stress. Aleksandra Piechota, Andrzej Polańczyk, Anna Gorąca (p. 28) Abstract / Article (PDF format) 9-Methyl-beta-carboline has restorative effects in an animal model of Parkinson's disease. Catrin Wernicke, Julian Hellmann, Barbara Zięba, Katarzyna Kuter, Krystyna Ossowska, Monika Frenzel, Norbert A. Dencher, Hans Rommelspacher (p. 35) Abstract / Article (PDF format) Effects of blockade of central dopamine D1 and D2 receptors on thermoregulation, metabolic rate and running performance. Cláudio H. Balthazar, Laura H. R. Leite, Roberta M. M. Ribeiro, Danusa D. Soares, Cândido C. Coimbra (p. 54) Abstract / Article (PDF format) Effects of 2-chloroadenosine on cortical epileptic afterdischarges in immature rats. Marie Pometlová, Hana Kubová, Pavel Mareš (p. 62) Abstract / Article (PDF format) Synthesis and pharmacological evaluation of pyrrolidin-2-one derivatives as antiarrhythmic, antihypertensive and alpha-adrenolytic agents. Katarzyna Kulig, Cindy Spieces, Jacek Sapa, Christa Caspers, Barbara Filipek, Barbara Malawska (p. 68) Abstract / Article (PDF format) Does nebivolol influence serum concentrations of proinflammatory cytokines in hypertensive (SHR) and normotensive (WKY) rats?. Dorota Górska, Michał Dudarewicz, Elżbieta Czarnecka, Dariusz Andrzejczak (p. 86) Abstract / Article (PDF format) Estrogen-induced relaxation of the rat tail artery is attenuated in rats with pulmonary hypertension. Ivan Kocić, Renata Szczepańska, Iga Wapniarska (p. 95) Abstract / Article (PDF format) Effects of statins on nitric oxide/cGMP signaling in human umbilical vein endothelial cells. Claudia Meda, Christian Plank, Olga Mykhaylyk, Kurt Schmidt, Bernd Mayer (p. 100) Abstract / Article (PDF format) Gastric anti-ulcerative and anti-inflammatory activity of metyrosine in rats. Abdulmecit Albayrak, Beyzagul Polat, Elif Cadirci, Ahmet Hacimuftuoglu, Zekai Halici, Mine Gulapoglu, Fatih Albayrak, Halis Suleyman (p. 113) Abstract / Article (PDF format) Metabolic and monocyte-suppressing actions of fenofibrate in patients with mixed dyslipidemia and early glucose metabolism disturbances. Robert Krysiak, Aldona Stachura-Kułach, Bogusław Okopień (p. 120) Abstract / Article (PDF format) N-acetylcysteine inhibits IL-8 and MMP-9 release and ICAM-1 expression by bronchoalveolar cells from interstitial lung disease patients. Dorota M. Radomska-Leśniewska, Ewa Skopińska-Różewska, Ewa Jankowska-Steifer, Małgorzata Sobiecka, Anna M. Sadowska, Agata Hevelke, Jacek Malejczyk (p. 131) Abstract / Article (PDF format) Local pulmonary opioid network in patients with lung cancer: a putative modulator of respiratory function. Małgorzata Krajnik, Michael Schäfer, Piotr Sobański, Janusz Kowalewski, Elżbieta Bloch-Bogusławska, Zbigniew Zylicz, Shaaban A. Mousa (p. 139) Abstract / Article (PDF format) Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression. Nian-Hong Chen, Jian-Wen Liu, Jian-Jiang Zhong (p. 150) Abstract / Article (PDF format) Fluvastatin increases tyrosinase synthesis induced by alpha-melanocyte-stimulating hormone in B16F10 melanoma cells. Ryszard Galus, Justyna Niderla, Dariusz Śladowski, Emir Sajjad, Krzysztof Włodarski, Jarosław Jóźwiak (p. 164) Abstract / Article (PDF format) Systemic perfluorohexane attenuates lung injury induced by lipopolysaccharide in rats: the role of heme oxygenase-1. Zhi-Jun Ge, Guo-Jun Jiang, Yan-Ping Zhao, Guo-Xiang Wang, Yong-Fei Tan (p. 170) Abstract / Article (PDF format) Strong antioxidant activity of carane derivatives. Tadeusz Librowski, Andrzej Moniczewski (p. 178) Abstract / Article (PDF format) Scavenging and antioxidant potential of physiological taurine concentrations against different reactive oxygen/nitrogen species. Max W. S. Oliveira, Juliane B. Minotto, Marcos R. de Oliveira, Alfeu Zanotto-Filho, Guilherme A. Behr, Ricardo F. Rocha, José C. F. Moreira, Fábio Klamt (p. 185) Abstract / Article (PDF format) SHORT COMMUNICATION Effect of p-isopropoxyphenylsuccinimide monohydrate on the anticonvulsant action of carbamazepine, phenobarbital, phenytoin and valproate in the mouse maximal electroshock-induced seizure model. Jarogniew J. Łuszczki, Sergey L. Kocharov, Stanisław J. Czuczwar (p. 194) Abstract / Article (PDF format)

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REVIEW - Retigabine: the newer potential antiepileptic drug. Piotr Czuczwar, Agnieszka Wojtak, Anna-Cioczek Czuczwar, Jolanta Parada-Turska, Ryszard Maciejewski, Stanisław J. Czuczwar (p. 211) Abstract / Article (PDF format) REVIEW - Guillain-Barré syndrome (GBS). Anand B. Pithadia, Nimisha Kakadia (p. 220) Abstract / Article (PDF format) REVIEW - COX-2 as a target for cancer chemotherapy. Nilanjan Ghosh, Rituparna Chaki, Vivekananda Mandal, Subhash C. Mandal (p. 233) Abstract / Article (PDF format) Effect of acute and chronic treatment with QCF-3 (4-benzylpiperazin-1-yl) (quinoxalin-2-yl) methanone, a novel 5-HT3 receptor antagonist, in animal models of depression. Thangaraj Devadoss, Dilip K. Pandey, Radhakrishnan Mahesh, Shushil K. Yadav (p. 245) Abstract / Article (PDF format) Buspirone improves 6-hydroxydopamine-induced catalepsy through stimulation of nigral 5-HT1A receptors in rats. Alireza M. Nayebi, Siyamak R. Rad, Mehdi Saberian, Saeid Azimzadeh, Morteza Samini (p. 258) Abstract / Article (PDF format) Pregnenolone sulfate infused in lateral septum of male rats impairs novel object recognition memory. Federico Nanfaro, Ricardo Cabrera, Vanesa Bazzocchini, Myrian Laconi, Roberto Yunes (p. 265) Abstract / Article (PDF format) Evaluation of the anticonvulsant activity of 6-(4-chlorophenyoxy)-tetrazolo[5,1-a]phthalazine in various experimental seizure models in mice. Xian-Yu Sun, Cheng-Xi Wei, Xian-Qing Deng, Zhi-Gang Sun, Zhe-Shan Quan (p. 273) Abstract / Article (PDF format) Pharmaco-EEG-based assessment of the interaction between ethanol and oxcarbazepine. Bogusława Pietrzak, Elżbieta Czarnecka (p. 278) Abstract / Article (PDF format) Anti-inflammatory plasma cytokines in children and adolescents with migraine headaches. Leszek Boćkowski, Joanna Śmigielska-Kuzia, Wojciech Sobaniec, Beata Żelazowska-Rutkowska, Wojciech Kułak, Krzysztof Sendrowski (p. 287) Abstract / Article (PDF format) Analysis of the excitatory motor response evoked by nicotinic and muscarinic blockade of ovine small bowel. Krzysztof W. Romański (p. 292) Abstract / Article (PDF format) Effects of aspirin on the levels of hydrogen sulfide and sulfane sulfur in mouse tissues. Anna Bilska, Małgorzata Iciek, Inga Kwiecień, Karol Kaniecki, Magdalena Paliborek, Eugeniusz Somogyi, Joanna Piotrowska, Bogdan Wiliński, Marta Góralska, Zbigniew Srebro, Lidia Włodek (p. 304) Abstract / Article (PDF format) Aldosterone augments LOX-1-mediated low-density lipoprotein uptake in human umbilical artery endothelial cells. Ashraf Taye, Tatsuya Sawamura, Henning Morawietz (p. 311) Abstract / Article (PDF format) Anticancer activity of newly synthesized azaphenothiazines from NCI's anticancer screening bank. Krystian Pluta, Małgorzata Jeleń, Beata Morak-Młodawska, Michał Zimecki, Jolanta Artym, Maja Kocięba (p. 319) Abstract / Article (PDF format) Modulation of P-glycoprotein activity by the substituted quinoxalinone compound QA3 in adriamycin-resistant K562/A02 cells. Li-Rui Sun, Julia Li Zhong, Shu-Xiang Cui, Xun Li, Stephen Geoffrey Ward, Yan-Qiu Shi, Xiao-Fan Zhang, Yan-Na Cheng, Jian-Jun Gao, Xian-Jun Qu (p. 333) Abstract / Article (PDF format) Effect of simvastatin on nitric oxide synthases (eNOS, iNOS) and arginine and its derivatives (ADMA, SDMA) in ischemia/reperfusion injury in rat liver. Małgorzata Trocha, Anna Merwid-Ląd, Andrzej Szuba, Ewa Chlebda, Małgorzata Pieśniewska, Tomasz Sozański, Adam Szeląg (p. 343) Abstract / Article (PDF format) Selenitetriglicerydes affect CYP1A1 and QR activity by involvement of reactive oxygen species and Nrf2 transcription factor. Piotr Suchocki, Irena Misiewicz-Krzemińska, Katarzyna Skupińska, Katarzyna Niedźwiecka, Katarzyna Lubelska, Zbigniew Fijałek, Teresa Kasprzycka-Guttman (p. 352) Abstract / Article (PDF format) Activities of biotransformation enzymes and flubendazole metabolism in lambs (Ovis aries): effect of gender and flubendazole therapy. Hana Bártiková, Veronika Křižová, Martina Štěpničková, Jiři Lamka, Vladimir Kubiček, Lenka Skálová, Barbora Szotáková (p. 362) Abstract / Article (PDF format) Residual fraction of the area under the curve as a qualitative criterion in pharmacokinetic studies. Tomasz Grabowski, Jerzy J. Jaroszewski, Piotr Jakubowski (p. 374) Abstract / Article (PDF format) SHORT COMMUNICATIONS Effects of sildenafil on pentylenetetrazol-induced convulsions in mice and amygdala-kindled seizures in rats. Dorota Nieoczym, Katarzyna Socała, Chris Rundfeldt, Piotr Wlaź (p. 383) Abstract / Article (PDF format) Effects of sarcosine, a glycine transporter type 1 inhibitor, in two mouse seizure models. Katarzyna Socała, Dorota Nieoczym, Chris Rundfeldt, Piotr Wlaź (p. 392) Abstract / Article (PDF format) Carbamazepine intoxication in alcohol dependent epileptic patients. Wojciech Piekoszewski, Ewa Florek, Dorota Szpak, Lucyna Kramer, Wojciech Jawień (p. 398) Abstract / Article (PDF format) Early co-administration of vitamin E acetate and methylcobalamin improves thermal hyperalgesia and motor nerve conduction velocity following sciatic nerve crush injury in rats. Aashish S. Morani, Subhash L. Bodhankar (p. 405) Abstract / Article (PDF format) Antiplatelet effect of statins is augmented in diabetic rabbits. Ivan Kocić, Beata Racek-Król, Iga Wapniarska, Izabela Rusiecka, Robert Wasilewski, Marcin Bitel (p. 410) Abstract / Article (PDF format) Synthesis and cytotoxic activity of G3 PAMAM-NH2 dendrimer-modified digoxin and proscillardin A conjugates in breast cancer cells. Katarzyna Winnicka, Krzysztof Bielawski, Anna Bielawska (p. 414) Abstract / Article (PDF format) Abstracts of the Third Conference on PROGRESS IN EPILEPSY AND ANTIEPILETIC DRUGS (p. 427) (PDF format)

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Editorial. Stefan Chłopicki (p. 452) (PDF Format) Welcome address. Lady Daphne Vane (p. 453) (PDF format) Sir John Robert Vane (1927-2004). Ryszard J. Gryglewski (p. 454) (PDF format) REVIEW - Vane blood-bathed technique reveals the significance of adrenergic reaction in myocardial infarction. Krystyna Herbaczyńska-Cedro, Leszek Ceremużyński (p. 457) Abstract / Article (PDF format) REVIEW - Vane's blood-bathed organ technique adapted to examine the endothelial effects of cardiovascular drugs in vivo. Ryszard J. Gryglewski, Zygmunt Mackiewicz (p. 462) Abstract / Article (PDF format) REVIEW - Red blood cells (RBCs), epoxyeicosatrienoic acids (EETs) and adenosine triphosphate (ATP). Houli Jiang, Gail D. Anderson, John C. McGiff (p. 468) Abstract / Article (PDF format) REVIEW - Regulation of cAMP by phosphodiesterases in erythrocytes. Shaquria P. Adderley, Randy S. Sprague, Alan H. Stephenson, Madelyn S. Hanson (p. 475) Abstract / Article (PDF format) Nicotinamide N-methyltransferase (NNMT) and 1-methylnicotinamide (MNA) in experimental hepatitis induced by concanavalin A in the mouse. Magdalena Sternak, Tamara I. Khomich, Andrzej Jakubowski, Małgorzata Szafarz, Wojciech Szczepański, Magdalena Białas, Marta Stojak, Joanna Szymura-Oleksiak, Stefan Chłopicki (p. 483) Abstract / Article (PDF format) Endurance training increases exercise-induced prostacyclin release in young, healthy men – relationship with VO2max. Jerzy A. Zoladz, Joanna Majerczak, Krzysztof Duda, Stefan Chłopicki (p. 494) Abstract / Article (PDF format) REVIEW - Transcellular biosynthesis of eicosanoids. Angelo Sala, Giancarlo Folco, Robert C. Murphy (p. 503) Abstract / Article (PDF format) REVIEW - Anti-allergic drugs and the Annexin-A1 system. Samia Yazid, Samir S. Ayoub, Egle Solito, Simon McArthur, Phuong Vo, Neil Dufton, Roderick J. Flower (p. 511) Abstract / Article (PDF format) REVIEW - Vane's discovery of the mechanism of action of aspirin changed our understanding of its clinical pharmacology. Regina M. Botting (p. 518) Abstract / Article (PDF format) REVIEW - Aspirin-induced asthma: a tribute to John Vane as a source of inspiration. Andrzej Szczeklik (p. 526) Abstract / Article (PDF format) REVIEW - NSAIDs and cardiovascular disease: transducing human pharmacology results into clinical read-outs in the general population. Marta L. Capone, Stefania Tacconelli, Luis Garcia Rodriguez, Paola Patrignani (p. 530) Abstract / Article (PDF format) REVIEW - Cytochrome P450-dependent metabolism of omega-6 and omega-3 long-chain polyunsaturated fatty acids. Cosima Arnold, Anne Konkel, Robert Fischer, Wolf-Hagen Schunck (p. 536) Abstract / Article (PDF format) REVIEW - New light on the anti-colitic actions of therapeutic aminosalicylates: the role of heme oxygenase. Brendan J.R. Whittle, Csaba Varga (p. 548) Abstract / Article (PDF format)

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OBITUARY - Professor Zbigniew Stanisław Herman - pharmacologist, physician (1935-2010). Ewa Obuchowicz (p. 561) (PDF format) REVIEW - Potential role of the 5-HT6 receptor in depression and anxiety: an overview of preclinical data. Anna Wesołowska (p. 564) Abstract / Article (PDF format) REVIEW - Role of oxycodone and oxycodone/naloxone in cancer pain management. Wojciech Leppert (p. 578) Abstract / Article (PDF format) REVIEW - Immunological aspects of epilepsy. Radosław Zarczuk, Dariusz Łukasik, Marian Jędrych, Kinga K. Borowicz (p. 592) Abstract / Article (PDF format) Neonatal DSP-4 treatment impairs 5-HT1B receptor reactivity in adult rats. Behavioral and biochemical studies. Marzena Ferdyn-Drosik, Przemysław Nowak, Kamila Bojanek, Michał Bałasz, Jacek Kasperski, Dariusz Skaba, Rafał Muchacki, Richard M. Kostrzewa (p. 608) Abstract / Article (PDF format) Involvement of 5-hydroxytryptamine type 3 receptors in sevoflurane-induced hypnotic and analgesic effects in mice. Li-Hua Hang, Dong-Hua Shao, Hong Wang, Jian-Ping Yang (p. 621) Abstract / Article (PDF format) Effects of sildenafil treatment on the development of tolerance to diazepam-induced motor impairment and sedation in mice. Sylwia Talarek, Jolanta Orzelska, Joanna Listos, Sylwia Fidecka (p. 627) Abstract / Article (PDF format) Hesperidin pre-treatment attenuates NO-mediated cerebral ischemic reperfucion injury and memory dysfunction. Vaibhav Gaur, Anil Kumar (p. 635) Abstract / Article (PDF format) Chronic ethanol exposure changes dopamine D2 receptor splicing during retinoic acid-induced differentiation of human SH-SY5Y cells. Catrin Wernicke, Julian Hellmann, Ulrich Finckh, Hans Rommelspacher (p. 649) Abstract / Article (PDF format) Intracerebroventricular administration of riluzole prevents morphine-induced apoptosis in the lumbar region of the rat spinal cord. Kambiz Hassanzadeh, Bohlool Habibi-asl, Leila Roshangar, Mahboob Nemati, Masood Ansarin, Safar Farajnia (p. 664) Abstract / Article (PDF format) Effects of chromium picolinate on vascular reactivity and cardiac ischemia-reperfusion injury in spontaneously hypertensive rats. Worku Abebe, Jun Yao Liu, Hereward Wimborne, Mahmood S. Mozaffari (p. 674) Abstract / Article (PDF format) Evaluation of terfenadine and ketoconazole-induced QT prolongation in conscious telemetered guinea pigs. Satyendra K. Rajput, Jitendra N. Singh, Shyam S. Sharma (p. 683) Abstract / Article (PDF format) Comparative effects of beta-carbolines on platelet aggregation and lipid membranes. Hironori Tsuchiya, Shuichi Ohmoto (p. 689) Abstract / Article (PDF format) Functional effects of polyamines via activation of human beta1- and beta2-adrenoceptors stably expressed in CHO cells. Clara Meana, Javier Bordallo, Carmen Bordallo, Lorena Suárez, Begona Cantabrana, Manuel Sánchez (p. 696) Abstract / Article (PDF format) Fullerenol C50(OH)24 prevents doxorubicin-induced acute cardiotoxicity in rats. Vukosava Milic Torres, Branislava Srdjenovic, Vesna Jacevic, Viktorija Dragojevic Simic, Aleksandar Djordjevic, Ana Luísa Simplício (p. 707) Abstract / Article (PDF format) Influence of long-term leflunomide treatment on serum amyloid concentration in rheumatoid arthritis patients. Bożena Targońska-Stępniak, Magdalena Dryglewska, Maria Majdan (p. 719) Abstract / Article (PDF format) Activation of the erythrocyte plasma membrane redox system by resveratrol: a possible mechanism for antioxidant properties. Syed Ibrahim Rizvi, Kanti Bhooshan Pandey (p. 726) Abstract / Article (PDF format) Effect of carnosine treatment on oxidative stress in serum, apoB-containing lipoproteins fraction and erythrocytes of aged rats. Ahmet F. Aydín, Zeynep Küskü-Kiraz, Semra Dogru-Abbasoglu, Müjdat Uysal (p. 733) Abstract / Article (PDF format) Investigation of allele and genotype frequencies of CYP2C9, CYP2C19 and VKORC1 in Iran. Negar Azarpira, Soha Namazi, Fatemeh Hendijani, Maryam Banan, Masumeh Darai (p. 740) Abstract / Article (PDF format) SHORT COMMUNICATIONS Pentazocine pretreatment suppresses fentanyl-induced cough. Qing Ai, YiPing Hu, YanJuan Wang, ShuoXiong Wu, Zhong Qin, Jun Wang, GuiLong Wang, JianYu Zhang, MingHao An (p. 747) Abstract / Article (PDF format) Influence of vitamin C on markers of oxidative stress in the earliest period of ischemic stroke. Monika Lagowska-Lenard, Zbigniew Stelmasiak, Halina Bartosik-Psujek (p. 751) Abstract / Article (PDF format) Effect of simvastatin treatment on rat livers subjected to ischemia/reperfusion. Małgorzata Trocha, Anna Merwid-Ląd, Ewa Chlebda, Małgorzata Pieśniewska, Tomasz Sozański, Adam Szeląg (p. 757) Abstract / Article (PDF format)

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REVIEW - Humanins, the neuroprotective and cytoprotective peptides with antiapoptotic and anti-inflammatory properties. Barbara Zapała, Łukasz Kaczyński, Beata Kieć-Wilk, Teresa Staszel, Anna Knapp, G. Hege Thoresen, Iwona Wybrańska, Aldona Dembińska-Kieć (p. 767) Abstract / Article (PDF format) REVIEW - Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB): a new potential therapeutic target in athertosclerosis?. Józefa Dąbek, Andrzej Kułach, Zbigniew Gąsior (p. 778) Abstract / Article (PDF format) Memory restorative role of statins in experimental dementia: an evidence of their cholesterol dependent and independent actions. Yogita Dalla, Nirmal Singh, Amteshwar Singh Jaggi, Dhandeep Singh (p. 784) Abstract / Article (PDF format) Rimonabant attenuates sensitization, cross-sensitization and cross-reinstatement of place preference induced by nicotine and ethanol. Grażyna Biała, Barbara Budzyńska (p. 797) Abstract / Article (PDF format) Influence of ethacrynic acid on the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock seizure model. Krzysztof Łukawski, Grażyna Świderska, Jarogniew J. Łuszczki, Stanisław J. Czuczwar (p. 808) Abstract / Article (PDF format) Cytosolic phospholipase A2 inhibition is involved in the protective effect of nortriptyline in primary astrocyte cultures exposed to combined oxygen-glucose deprivation. Bożena Gabryel, Anna Bielecka, Anna Stolecka, Jacek Bernacki, Józef Langfort (p. 814) Abstract / Article (PDF format) Metformin has adenosine-monophosphate activated protein kinase (AMPK)-independent effects on LPS-stimulated rat primary microglial cultures. Krzysztof Łabuzek, Sebastian Liber, Bożena Gabryel, Bogusław Okopień (p. 827) Abstract / Article (PDF format) New antinociceptive agents related to dihydrosphingosine. Fátima de Campos Buzzi, Mauricio Fracasso, Valdir Cechinel Filho,Ricardo Escarcena, Esther del Olmo, Arturo San Feliciano (p. 849) Abstract / Article (PDF format) Effects of subcutaneous and intracerebroventricular injection of physostigmine on the acute corneal nociception in rats. Esmaeal Tamaddonfard, Nasrin Hamzeh-Gooshchi (p. 858) Abstract / Article (PDF format) Pinealectomy aggravates acute pancreatitis in the rat. Jolanta Jaworek, Krystyna Żwirska-Korczala, Joanna Szklarczyk, Katarzyna Nawrot-Porąbka, Anna Leja-Szpak, Andrzej K. Jaworek, Romana Tomaszewska (p. 864) Abstract / Article (PDF format) Effect of clofibrate on vascular reactivity in a model of high blood pressure secondary to aortic coarctation. Luz Graciela Cervantes-Pérez, María de la Luz Ibarra-Lara, María Esther Rubio, Bruno Escalante, Francisca Pérez-Severiano, Elizabeth Soria-Castro, Margarita del Carmen Ramírez-Ortega, María Alicia Sánchez-Mendoza (p. 874) Abstract / Article (PDF format) Hypotensive effect of atorvastatin is not related to changes in inflammation and oxidative stress. Agnieszka M. Kuklińska, Barbara Mroczko, Włodzimierz J. Musiał, Robert Sawicki, Anna Kozieradzka, Monika Usowicz-Szaryńska, Karol Kamiński, Małgorzata Knapp, Maciej Szmitkowski (p. 883) Abstract / Article (PDF format) Cigarette smoke-induced biochemical perturbations in human erythrocytes and attenuation by epigallocatechin-3-gallate – tea catechin. Adikesavan Gokulakrishnan, Abdul Rahman Liyakath Ali (p. 891) Abstract / Article (PDF format) Effects of curcumin on the skeletal system in rats. Joanna Folwarczna, Maria Zych, Henryk I. Trzeciak (p. 900) Abstract / Article (PDF format) Effect of thymoquinone on the lung pathology and cytokine levels of ovalbumin-sensitized guinea pigs. Rana Keyhanmanesh, Mohammad H. Boskabady, Saeed Khamneh, Yoosef Doostar (p. 910) Abstract / Article (PDF format) Modulation of in vivo immunoglobulin production by endogenous histamine and H1R and H2R agonists and antagonists. Trivendra Tripathi, Mohammad Shahid, Haris M. Khan, Mahendra Pal Singh Negi, Mashiatullah Siddiqui, Rahat A. Khan (p. 917) Abstract / Article (PDF format) Effect of erythropoietin, 5-fluorouracil and SN-38 on the growth of DLD-1 cells. Anna Tankiewicz-Kwedlo, Dariusz Pawlak, Tomasz Domaniewski, Włodzimierz Buczko (p. 926) Abstract / Article (PDF format) SHORT COMMUNICATIONS Family-based study of brain-derived neurotrophic factor (BDNF) gene polymorphism in alcohol dependence. Anna Grzywacz, Agnieszka Samochowiec, Andrzej Ciechanowicz, Jerzy Samochowiec (p. 938) Abstract / Article (PDF format) Dose-response relationship analysis of pregabalin doses and their antinociceptive effects in hot-plate test in mice. Jarogniew J. Łuszczki (p. 942) Abstract / Article (PDF format) Anti-apoptotic effects of hyperoside via inhibition of NR2B-containing NMDA receptors. Xiao-Nan Zhang, Jin-Mao Li, Qi Yang, Bin Feng, Shui-bing Liu, Zhao-Hui Xu, Yan-Yan Guo, Ming-Gao Zhao (p. 949) Abstract / Article (PDF format) Quantification of metformin by the HPLC method in brain regions, cerebrospinal fluid and plasma of rats treated with lipopolysaccharide. Krzysztof Łabuzek, Dariusz Suchy, Bożena Gabryel, Anna Bielecka, Sebastian Liber, Bogusław Okopień (p. 956) Abstract / Article (PDF format)

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REVIEW - Interleukin-1 (IL-1) in stress-induced activation of limbic-hypothalamic-pituitary adrenal axis. Anna Gądek-Michalska, Jan Bugajski (p. 969) Abstract / Article (PDF format) Important role of 3-methoxytyramine in the inhibition of cocaine sensitization by 1-methyl-1,2,3,4-tetrahydroisoquinoline: an in vivo microdialysis study. Agnieszka Wąsik, Irena Romańska, Lucyna Antkiewicz-Michaluk (p. 983) Abstract / Article (PDF format) Chronic ecstasy use increases neurotrophin-4 gene expression and protein levels in the rat brain. Homeira Hatami, Mohammad Ali Hossainpour-Faizi, Maryam Azarfarin, Parvin Azarfam (p. 998) Abstract / Article (PDF format) Effects of serotonin (5-HT)6 receptor ligands on responding for cocaine reward and seeking in rats. Katarzyna Fijał, Agnieszka Pachuta, Andrew C. McCreary, Karolina Wydra, Ewa Nowak, Mariusz Papp, Przemysław Bieńkowski, Jolanta Kotlińska, Małgorzata Filip (p. 1005) Abstract / Article (PDF format) Effect of metyrapone on the fluoxetine-induced change in extracellular dopamine, serotonin and their metabolites in the rat frontal cortex. Zofia Rogóż, Krystyna Gołembiowska (p. 1015) Abstract / Article (PDF format) Effects of melatonin in a place preference conditioning depend on the time of administration. Mariusz Papp, Ewa Litwa, Magdalena Łasoń-Tyburkiewicz, Piotr Gruca (p. 1023) Abstract / Article (PDF format) Effects of neurosteroids on the human corticotropin-releasing hormone gene. Bogusława Budziszewska, Anna Zając, Agnieszka Basta-Kaim, Monika Leśkiewicz, Małgorzata Steczkowska, Władysław Lasoń, Marek Kaciński (p. 1030) Abstract / Article (PDF format) 1-Methyl-1,2,3,4-tetrahydroisoquinoline and established uncompetitive NMDA receptor antagonists induce tolerance to excitotoxicity. Magdalena Kuszczyk, Marta Słomka, Lucyna Antkiewicz-Michaluk, Elżbieta Salińska, Jerzy W. Łazarewicz (p. 1041) Abstract / Article (PDF format) Neuroprotective potential of mGluR5 antagonist MTEP: effects on kainate-induced excitotoxicity in the rat hippocampus. Helena Domin, Barbara Zięba, Krystyna Gołembiowska, Magdalena Kowalska, Anna Dziubina, Maria Śmiałowska (p. 1051) Abstract / Article (PDF format) Influence of antidepressant drugs on chlorpromazine metabolism in human liver - an in vitro study. Jacek Wójcikowski, Władysława A. Daniel (p. 1062) Abstract / Article (PDF format) Amino acid metabolic processes in the temporal lobes assessed by proton magnetic resonance spectroscopy (1H MRS) in children with Down syndrome. Joanna Śmigielska-Kuzia, Leszek Boćkowski, Wojciech Sobaniec, Wojciech Kułak, Krzysztof Sendrowski (p. 1070) Abstract / Article (PDF format) Modulatory effect of high saturated fat diet-induced metabolic disturbances on angiogenic response in hepatocyte RXRalpha knockout mice. Urszula Raźny, Łukasz Wątor, Anna Polus, Beata Kieć-Wilk, Yu-Jui Yvonne Wan, Grzegorz Dyduch, Romana Tomaszewska, Aldona Dembińska-Kieć (p. 1078) Abstract / Article (PDF format) Hemostatic effects of simvastatin in subjects with impaired fasting glucose. Robert Krysiak, Anna Gdula-Dymek, Bogusław Okopień (p. 1090) Abstract / Article (PDF format) Hemostatic effects of fenofibrate in patients with mixed dyslipidemia and impaired fasting glucose. Robert Krysiak, Gabriela Handzlik, Bogusław Okopień (p. 1099) Abstract / Article (PDF format) Effects of standard treatment on the dynamics of matrix metalloproteinases gene expression in patients with acute coronary syndromes. 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