Department of Brain Biochemistry
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Vitamin D3 and Ischemic Stroke: A Narrative Review.
Władysław Lasoń, Danuta Jantas, Monika Leśkiewicz, Magdalena Regulska, Agnieszka Basta-Kaim
Antioxidants (Basel, Switzerland), 2120 10.3390/antiox11112120
PMID:36358492 -
Introduction to the Special Section on
Katarzyna Głombik, Katarzyna Kuter-Nowak
Pharmacological reports : PR, 10.1007/s43440-022-00421-9
PMID:36149597 -
The influence of preconditioning with low dose of LPS on paraquat-induced neurotoxicity, microglia activation and expression of α-synuclein and synphilin-1 in the dopaminergic system.
Katarzyna Z Kuter, Maria Śmiałowska, Krystyna Ossowska
Pharmacological reports : PR, 10.1007/s43440-021-00340-1
PMID:34762280 -
The Impact of the Combined Administration of 1MeTIQ and MK-801 on Cell Viability, Oxidative Stress Markers, and Glutamate Release in the Rat Hippocampus.
Agnieszka Wąsik, Magdalena Białoń, Danuta Jantas, Marcelina Żarnowska
Neurotoxicity research, 10.1007/s12640-021-00428-9
PMID:34665405 -
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Danuta Jantas, Janusz Malarz, Thanh Nguyen Le, Anna Stojakowska
International journal of molecular sciences, 10363 10.3390/ijms221910363
PMID:34638702 -
Preclinical Evidence for the Interplay between Oxidative Stress and RIP1-Dependent Cell Death in Neurodegeneration: State of the Art and Possible Therapeutic Implications.
Danuta Jantas, Władysław Lasoń
Antioxidants (Basel, Switzerland), 1518 10.3390/antiox10101518
PMID:34679652 -
Beyond the GFAP-Astrocyte Protein Markers in the Brain.
Agnieszka M Jurga, Martyna Paleczna, Justyna Kadluczka, Katarzyna Z Kuter
Biomolecules, 1361 10.3390/biom11091361
PMID:34572572 -
Antiparkinsonian-like effects of CPL500036, a novel selective inhibitor of phosphodiesterase 10A, in the unilateral rat model of Parkinson's disease.
Tomasz Lenda, Krystyna Ossowska, Klemencja Berghauzen-Maciejewska, Mikołaj Matłoka, Jerzy Pieczykolan, Maciej Wieczorek, Jolanta Konieczny
European journal of pharmacology, S0014-2999(21)00614-2 10.1016/j.ejphar.2021.174460
PMID:34469756 -
Increased Beta-Hydroxybutyrate Level Is Not Sufficient for the Neuroprotective Effect of Long-Term Ketogenic Diet in an Animal Model of Early Parkinson's Disease. Exploration of Brain and Liver Energy Metabolism Markers.
Katarzyna Z Kuter, Łukasz Olech, Urszula Głowacka, Martyna Paleczna
International journal of molecular sciences, 7556 10.3390/ijms22147556
PMID:34299176 -
Neuroprotective Effects of Methyl Caffeate against Hydrogen Peroxide-Induced Cell Damage: Involvement of Caspase 3 and Cathepsin D Inhibition.
Danuta Jantas, Jakub Chwastek, Janusz Malarz, Anna Stojakowska, Władysław Lasoń
Biomolecules, E1530 10.3390/biom10111530
PMID:33182454 -
Back and to the Future: From Neurotoxin-Induced to Human Parkinson's Disease Models.
Mikko Airavaara, Ilmari Parkkinen, Julia Konovalova, Katrina Albert, Piotr Chmielarz, Andrii Domanskyi
Current protocols in neuroscience, 10.1002/cpns.88
PMID:32049438 -
Overview of General and Discriminating Markers of Differential Microglia Phenotypes.
Agnieszka M Jurga, Martyna Paleczna, Katarzyna Z Kuter
Frontiers in cellular neuroscience, 10.3389/fncel.2020.00198
PMID:32848611 -
The role of glia in Parkinson's disease: Emerging concepts and therapeutic applications.
Katarzyna Z Kuter, M Angela Cenci, Anna R Carta
Progress in brain research, S0079-6123(20)30021-2 10.1016/bs.pbr.2020.02.004
PMID:32247363 -
MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System.
Emmi Pakarinen, Tatiana Danilova, Vootele Võikar, Piotr Chmielarz, Petteri Piepponen, Mikko Airavaara, Mart Saarma, Maria Lindahl
eNeuro, ENEURO.0477-19.2019 10.1523/ENEURO.0477-19.2019
PMID:32005751 -
Neuroprotective Effects of Necrostatin-1 Against Oxidative Stress-Induced Cell Damage: an Involvement of Cathepsin D Inhibition.
Danuta Jantas, Jakub Chwastek, Beata Grygier, Władysław Lasoń
Neurotoxicity research, 10.1007/s12640-020-00164-6
PMID:31960265
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Aneta Fraczek-Szczypta, Danuta Jantas, Filip Ciepiela, Justyna Grzonka. Graphene oxide-conductive polymer nanocomposite coatings obtained by the EPD method as substrates for neurite outgrowth. Diamond & Related Materials 102 (2020) 107663.
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Marek Piotrowski, Danuta Jantas, Monika Leśkiewicz, Krzysztof Szczepanowicz, Piotr Warszyński, Władysław Lasoń. Polyelectrolyte-coated nanocapsules containing cyclosporine A protect neuronal-like cells against oxidative stress-induced cell damage. Colloids and Surfaces A: Physicochemical and Engineering Aspects Volume 555, 20 October 2018, Pages 264-269.
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Aneta Fraczek-Szczypta, Danuta Jantas, Filip Ciepiela, Justyna Grzonka, Andrzej Bernasike, Mateusz Marzec. Carbon nanomaterials coatings – Properties and influence on nerve cells response. Diamond and Related Materials Volume 84, April 2018, Pages 127–140.
- M. Szczęch, K. Szczepanowicz, D. Jantas, M. Piotrowski, A. Kida, W. Lasoń, P. Warszyński. Neuroprotective action of undecylenic acid (UDA) encapsulated into PCL nanocarriers. Colloids and Surfaces A 532 (2017) 41–47.
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Marek Piotrowski, Krzysztof Szczepanowicz, Danuta Jantas, Monika Leskiewicz, Władysław Lason, Piotr Warszynski. Emulsion-core and polyelectrolyte-shell nanocapsules: biocompatibility and neuroprotection against SH-SY5Y cells. J Nanopart Res (2013) 15:1-12.
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Gręda A., Jantas D. Dysfunkcje mitochondriów w chorobach neurodegeneracyjnych: potencjalny punkt uchwytu dla leków neuroprotekcyjnych. Postępy Biologii Komórki, TOM 39 2012 NR 3 (321–344). Review in Polish.
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Danuta Jantas. Thyreoliberin (TRH) – the regulatory neuropeptide of CNS homeostasis. Advances in Cell Biology 2010, 2:138-152.
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Kuter, Cenci, Carta, The role of glia in Parkinson's disease: Emerging concepts and therapeutic applications, Progress in Brain Research Volume 252, 2020, Pages 131-168
Kuter K.Z., Cenci M.A., Carta A.R.
"The role of glia in Parkinson's disease: Emerging concepts and therapeutic applications"
Progress in Brain Research Volume 252, 2020, Pages 131-168
part of Recent Advances in Parkinson's Disease, edited by Björklund and CenciElsevier -
Astrocytes and microglia in Parkinson’s disease and its animal models. In: The Neuroscience of Parkinson's Disease. Vol 2. Genetics, neurology, behavior, and diet in Parkinson’s disease, 2020, Chapter 6, pp 83-101
Katarzyna Kuter
Astrocytes and microglia in Parkinson’s disease and its animal models. In: The Neuroscience of Parkinson's Disease. Vol 2. Genetics, neurology, behavior, and diet in Parkinson’s disease, 2020, Chapter 6, pp 83-101, Editors: Colin Martin and Victor Preedy, ISBN: 978-0-12-815950-7, published by Academic Press, Imprint of Elsevier, Published Date: 18th September 2020 - Jantas D. Cell-Based Systems of Depression: An Overview. In: Herbal Medicine in Depression. Ed. Clara Grosso. Springer, Switzerland 2016, p. 75-117. DOI 10.1007/978-3-319-14021-6.
- Lasoń W., Jantas D. Rola epigenetyki w mechanizmach i leczeniu padaczki (The role of epigenetics in pathomechanisms and epilepsy treatment). Article In Polish. Epileptologia 2009, 17:113-122.
- Jantas-Skotniczna D. Estrogeny – nie tylko hormony płciowe (Rola estrogenów w Ośrodkowym Układzie Nerwowym). [Estrogens – not only sexual hormons (The role of estrogens In Central Nervous System)]. Wszechświat, 2004; 105: 191-194. Review. Polish.
- Jantas-Skotniczna D. ALS – cichy zabójca (Nasze szanse w walce ze stwardnieniem bocznym zanikowym). [ALS – the sileni killer (Our chances to combat Amyotropic Lateral Sclerosis)]. Wszechświat, 2006; 107: 31-33. Review. Polish.
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The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopamine receptor ligands, Danuta Jantas, PhD
Consortium partner in project SONATA 17 UMO-2021/43/D/NZ7/00891 -
Project PASIFIC Call 1 TheraLanOx "Neuroprotective properties of theranostic lanthanide oxide nanoparticles against neurotoxin-induced cellular models of Parkinson’s disease", Danuta Jantas, PhD
Project PI: Dr Rugmani Meenambal; project supervisors: Dr hab. Danuta Jantas and Prof. dr hab. Piotr Warszyński
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Hybrid carbon composites for stimulation of cells of the central nervous system, Danuta Jantas, PhD
Consortium partner in project OPUS 20 2020/39/B/ST5/02126 -
grant NCN OPUS18 2019/35/B/NZ7/02862 Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic targets for Parkinson’s disease, Katarzyna Kuter - Nowak, PhD
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, Katarzyna Kuter - Nowak, PhD
NCN grant, OPUS 14 [2018-08-03 - 2021-08-02]
Title: "How microglia-astrocyte interaction affects neuronal functioning
in the dopaminergic system. Analysis of protective potential of drugs changing the glial phenotype"
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Evaluation of the influence of progressive noradrenergic neurodegeneration on dopaminergic system functioning in context of presymptomatic phase of Parkinson's disease., Grzegorz Kreiner, PhD
OPUS13 2017/25/B/NZ7/02406
Principal Investigator: Dr Grzegorz Kreiner -
, Professor Irena Nalepa, PhD
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, Professor Irena Nalepa, PhD
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Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment, Grzegorz Kreiner, PhD
OPUS7 2014/13/B/NZ7/02293
Principal Investigator: Dr Grzegorz Kreiner -
, Katarzyna Kuter - Nowak, PhD
“MOBILNOSC PLUS” scholarship sponsored by Polish Ministry of Science and Higher Education.
Title: „Protective role of astrocytes in the process of neurodegeneration of dopaminergic cells and during functional compensation of this process. Analysis of function and architecture of mitochondrial oxphos complexes and supercomplexes in animal models of early Morbus Parkinson.”
Performed during three 6 month visits at Technische Universität Darmstadt, Darmstadt, Germany in group of Prof. Norbert A. Dencher. -
NCN grant, OPUS 3, Katarzyna Kuter - Nowak, PhD
OPUS 3 grant nr 2012/05/B/NZ4/02599 financed by National Science Centre (NCN).
Title: „The role of astrocytes and cellular metabolism in functional compensation of degeneration of dopaminergic system in threats brain. Analysis of expression of AMPK and energy sensing proteins in aspect of Parkinson's disease.”
Performed in the Institute of Pharmacology, Polish Academy of Sciences – project leader. -
The study on the role of metabotropic glutamate receptor subtype 8 (mGluR8) in cancer cells - potential target for new anticancer drugs, Danuta Jantas, PhD
Grant NCN OPUS 3 2012/05/B/NZ3/00452.
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Pharmacological evaluation of possible neuroprotective strategies in novel genetic mouse models of progressive neurodegeneration, based on tissue specific inducible Cre/loxP system , Grzegorz Kreiner, PhD
OPUS2 2011/03/B/NZ7/05949
Principal Investigator: Dr Grzegorz Kreiner
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The study on the neuroprotective potential of metabotropic glutamate group II and III receptors in in vitro and in vivo apoptosis models, Danuta Jantas, PhD
Grant KBN nr N N405 611638. -
, Professor Irena Nalepa, PhD
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2020 - Bronze Cross of Merit from President of Poland; for significant contribution to science development in Poland, Danuta Jantas, PhD
Tuesday, 29 June 2021 -
Team Scientific Award of the 5th Medical Sciences PAS for a series of 3 publications "The role of astrocytes in mechanisms compensating for the degeneration of dopaminergic neurons and in the regulation of cellular energy of the black-striatal system in an animal model of early Parkinson's disease"., Katarzyna Kuter - Nowak, PhD
Wednesday, 11 December 2019 -
2017 - Publons Peer Review Award, Multidisciplinary, Danuta Jantas, PhD
Friday, 1 September 2017 -
2009 - Young Investigator Award, Neuropeptides Festival, Salzburg, Austria. , Danuta Jantas, PhD
Thursday, 23 July 2009 -
Award for publication woth high IF in 2018 granted by the Head of the Institute of Pharmacology, Katarzyna Kuter - Nowak, PhD
Monday, 30 November -0001
interests
techniques
- analysis and interpretation of big genomic data-sets
- cDNA microarrays
- chronic psychosocial stress
- conditioned place aversion
- conditioned place preference
- fear conditioning
- genotyping
- HPLC EC
- immune cells tissue cultures
- in vitro transfection
- mass sectroscopy
- microinfusions
- neurochemically specific lesions
- protein microarrays
- python programming
- spectroscopy UV-VIS
- tail flick test
- TLDA microarrays
keywords
- 6-OHDA
- Alzheimer disease
- animal models
- antidepressants
- apoptosis
- behavioural analysis
- bioinformatics
- depression
- drug addiction
- G-protein coupled receptors
- gene expression
- glia
- Glioblastoma
- glutamate
- glutamatergic receptors
- hippocampus
- imipramine
- ischemia
- metabotropic glutamate receptors
- mitochondrial proteins
- molecular biology
- mouse
- neurodegeneration
- neurons
- neuroprotection
- neurotoxicity
- neurotrophic factors
- NMDA receptor
- noradrenaline
- Parkinson's disease
- prefrontal cortex
- proteasome
- proteomics
- psychopharmacology
- rat
- second messengers
- signaling proteins
- stress
- synapse
- thalamus
- treatment-resistant depression